Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:HUMAN PROTHROMBIN COMPLEX-250IU
prescription
Prescription Medicine
info
image icons
Best Price

₹18421 with coupons & bank offers*

View

Pro-Throm Injection is used to prevent and treat bleeding. It is mainly used to rapidly reverse anticoagulation caused by blood thinners like warfarin during severe bleeding or when emergency surgery or invasive procedures are required. It works by replenishing vitamin K-dependent coagulation factors II, VII, IX, and X, and antithrombotic proteins C and S, to restore normal blood clotting and prevent excessive bleeding.

Read more
Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

HUMAN PROTHROMBIN COMPLEX-250IU

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pro-Throm Injection

Pro-Throm Injection is an injection used to quickly replace clotting factors in the blood. It is primarily prescribed to stop or prevent severe bleeding in people taking blood thinners who need urgent surgery or are experiencing a major bleeding episode.

Because this medicine is used in emergencies, it is typically given as a single injection rather than a daily routine. Since it is injected directly into a vein, food intake does not affect how it works. While recovering, resting and avoiding activities that increase bleeding risks can help support your results.

Some people may experience mild side effects like headache, nausea, or mild pain at the injection site. However, because this medicine affects how your blood clots, you must seek immediate medical attention if you notice signs of blood clots, such as sudden leg pain or shortness of breath.

Do not take this if you have a known history of severe allergic reactions to heparin or active blood clots. Before receiving it is important to tell your healthcare team if you have recently had a heart attack, stroke, or a history of blood clots.

This medicine can interact with other blood-clotting medications, which can change how well your blood clots. If you are pregnant, breastfeeding, or elderly, talk to your doctor or pharmacist about the specific risks and benefits in your situation. This medicine should only be used under the supervision of a specialist in children and people with kidney problems, as the dose and monitoring plan may vary depending on age, weight, and the underlying medical condition.

Uses of Pro-Throm Injection

Your doctor may recommend this injection to help manage the following conditions:

  • Urgent reversal of blood thinner therapy: It quickly restores clotting factor levels to stop bleeding in people taking blood thinners who are experiencing severe bleeding.
  • Preparation for emergency surgery: It helps prevent excessive bleeding during urgent surgical procedures in patients whose blood clotting is delayed due to blood-thinning medications.
  • Congenital clotting factor deficiency: In certain cases where specific clotting proteins are low, it helps temporarily restore normal clotting to manage bleeding risks.

Key Benefits

This injection may provide the following health benefits:

  • Helps control serious bleeding quickly: This medicine helps restore normal blood clotting, helping to control serious bleeding and reduce the risk of complications from excessive blood loss.
  • Supports urgent surgical procedures: By improving your body's ability to form blood clots, this medicine may help reduce the risk of excessive bleeding during or after emergency or planned surgery when rapid clotting correction is needed.
Side effects of Pro-Throm Injection
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Pro-Throm Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Pro-Throm Injection Works

Pro-Throm Injection works by delivering concentrated clotting factors directly into your bloodstream. It contains human clotting factors II, VII, IX, and X. Some formulations also contain proteins C and S. These are natural proteins made by the liver that help your blood form clots and stop bleeding. When you take certain blood thinners, these clotting factors may be reduced or blocked, making it harder for your blood to clot. This medicine quickly replaces these clotting factors, allowing your body to form strong clots and help control bleeding.
bannner image

Alcohol

Caution

It is not known if alcohol interacts with Pro-Throm Injection. Please consult your doctor if you have any concerns. However, avoid alcohol to prevent unpleasant reactions.

bannner image

Pregnancy

Caution

Inform the doctor if you are pregnant. Your doctor will prescribe it only if the benefits outweigh the risks.

bannner image

Breast Feeding

Consult your doctor

Consult your doctor before receiving Pro-Throm Injection while breastfeeding, as it's unclear if the medication passes into breast milk.

bannner image

Driving

Consult your doctor

The effect of Pro-Throm Injection on driving or operating heavy machinery is unknown. Drive or operate machinery only if you feel alert.

bannner image

Liver

Safe if prescribed

Please consult the doctor if you have liver impairments or diseases. The doctor may suggest it only if the benefits outweigh the risks.

bannner image

Kidney

Caution

If you have kidney impairments, inform your doctor before taking Pro-Throm Injection. The doctor may suggest it only if the benefits outweigh the risks.

bannner image

Children

Consult your doctor

Consult a doctor before giving Pro-Throm Injection to children, as its safety and effectiveness in children have not been established.

bannner image

Heart

Caution

Pro-Throm Injection can generally be used in patients with heart problems, but only under close medical supervision.

bannner image

Geriatrics

Caution

Geriatric patients (age 60 and above) can receive Pro-Throm Injection, but with careful medical supervision.

What if I have taken an overdose of Pro-Throm Injection

Since this medication is injected by healthcare professionals, an overdose is rare. If you suspect you have received too much or experience severe symptoms like chest pain or sudden breathing difficulties, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Limit foods high in Vitamin K: Since this medicine is often used to reverse blood thinners, ask your doctor about your dietary intake of green leafy vegetables (like spinach and kale), as sudden changes in vitamin K intake can affect how your blood clots.
  • Avoid alcohol: Do not drink alcohol during your recovery, as it can thin your blood and increase the risk of bleeding.
  • Prevent injuries: Use a soft-bristled toothbrush and an electric razor to minimise the risk of cuts and bleeding while your clotting levels are stabilising.
  • Stay hydrated: Drink plenty of water to help support healthy blood circulation, unless advised otherwise by your doctor.
health query

Have a query?

How Soon It Starts Working

The time required for Pro-Throm Injection to start to work: The time required for Pro-Throm Injection to show its action is unknown. The time for which the effects of Pro-Throm Injection last: The duration of action for Pro-Throm Injection is unknown.

What if you forget to take Pro-Throm Injection

Because it is typically given in a controlled hospital setting for emergencies, missing a dose is highly unlikely. However, if you are receiving this on a schedule at home and miss a dose, contact your healthcare provider immediately for instructions.

Storage

•Do not freeze the medicine, and protect it from direct light. •Keep all vials, needles, and injection sets safely out of reach of children and pets.

Drug Warnings

  • Watch for clot symptoms: Monitor for unusual swelling, pain, or redness in your legs for several days after the injection, as this medicine may increase the risk of blood clots.
  • Check your blood pressure: Your medical team will monitor your blood pressure and heart rate during and after the injection.
  • Monitoring: Your doctor will perform blood clotting tests (such as INR) before and after treatment to check your response and need for further treatment.
  • Who should not receive this medicine: Do not receive this medicine if you are allergic to any ingredients, have disseminated intravascular coagulation (DIC) unless advised by your doctor, or have active blood clots.
  • Source of the medicine: This medicine is made from human plasma (the liquid part of blood). It undergoes careful screening and pathogen reduction processes, such as virus inactivation and filtration methods, to reduce the risk of infection transmission. Although the risk is extremely low, it cannot be eliminated.
  • After your treatment: Your doctor may repeat INR tests to check your response. If you take blood thinners, your doctor will advise when to restart them. You may be monitored in the hospital until your condition is stable.

Drug-Drug Interactions

verifiedApollotooltip
  • Antifibrinolytic medicines (such as tranexamic acid): Using these medicines together may increase the risk of blood clots. Your doctor will decide if this combination is appropriate for you.
  • Blood thinners (such as warfarin, heparin, or apixaban): This medicine may reduce the effect of blood-thinning treatment. Your doctor will advise you when it is safe to restart or adjust your blood thinner.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Login/Sign Up

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Pro-Throm Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Habit Forming

No

Therapeutic Class

[HEMOSTATIC AGENTS]

FAQs

Pro-Throm Injection is used to prevent and treat bleeding. It is mainly used to rapidly reverse anticoagulation caused by blood thinners like warfarin during severe bleeding or when emergency surgery or invasive procedures are required.
Pro-Throm Injection works by replenishing vitamin K-dependent coagulation factors and antithrombotic proteins, restoring normal blood clotting and preventing excessive bleeding.
Pro-Throm Injection is administered by a healthcare professional through an intravenous (IV) infusion. Do not self-administer.
The common side effects of Pro-Throm Injection may include headache, nausea, vomiting, and dizziness. Most of these side effects do not require medical attention and gradually resolve over time. However, if they persist or worsen, please consult your doctor.
Having a history of blood clots can increase your risk of complications, so your doctor will carefully weigh the benefits against the risks. Talk to your doctor to discuss your medical history.
You should avoid activities that carry a high risk of physical injury or bleeding, as well as alcohol, which can affect blood clotting. Talk to your doctor for specific advice.
There is limited information on the safety of injection during pregnancy, so it is only used when necessary. Talk to your doctor to understand the risks and benefits.
It is a highly concentrated injection of specific clotting proteins, whereas a blood transfusion replaces whole blood or plasma. Talk to your doctor about which option is right for you.
Yes, your healthcare provider will likely monitor your blood clotting levels closely to ensure your blood is clotting safely. Talk to your doctor.
Your doctor will assess your condition and may repeat blood clotting tests or provide additional treatment if needed. Any further dose will be decided by your healthcare team based on your response and medical condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PRO2486
whatsapp Floating Button
Buy Now
Add to Cart