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  3. Pro-Throm Injection 1's

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Pro-Throm Injection 1's, Pack of 1 INJECTION
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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Pro-Throm Injection is used to prevent and treat bleeding. It is mainly used to rapidly reverse anticoagulation caused by blood thinners like warfarin during severe bleeding or when emergency surgery or invasive procedures are required. It works by replenishing vitamin K-dependent coagulation factors II, VII, IX, and X, and antithrombotic proteins C and S, to restore normal blood clotting and prevent excessive bleeding.

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Composition :

HUMAN PROTHROMBIN COMPLEX-250IU

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Pro-Throm Injection

Pro-Throm Injection belongs to hemostatic agents used to prevent and treat bleeding, mainly used to rapidly reverse anticoagulation caused by blood thinners like warfarin during severe bleeding or when emergency surgery or invasive procedures are required.

Pro-Throm Injection contains clotting factors (Factor II, Factor VII, Factor IX, Factor X), which work by replenishing vitamin K-dependent coagulation factors and antithrombotic proteins to restore normal blood clotting and prevent excessive bleeding.

In some cases, Pro-Throm Injection may cause side effects such as headache, nausea, vomiting, and dizziness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor immediately.

Inform your doctor if you are allergic to any components in Pro-Throm Injection or have conditions like disseminated intravascular coagulation or heparin-induced thrombocytopenia. Inform your doctor about any history of thromboembolic events, seizures, or liver/kidney impairments. Talk with your doctor if you have had a heart or blood vessel-related event within the past 3 months, including a heart attack, stroke, transient ischemic attack, unstable angina, severe peripheral vascular disease, or blood clots. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety and efficacy of Pro-Throm Injection in pediatric patients under 18 years of age have not been established. Let your doctor know if you use any prescription or nonprescription medications, including vitamins or mineral supplements or herbal products.

Uses of Pro-Throm Injection

Pro-Throm Injection is used to prevent and treat bleeding. The detailed uses of Pro-Throm Injection are as follows:<br/>• Treatment of Bleeding: Pro-Throm Injection helps to manage excessive bleeding in patients.<br/>• Reversal of Anticoagulation: Pro-Throm Injection used to reverse the effects of blood thinners like warfarin in emergencies.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Pro-Throm Injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Pro-Throm Injection is used to treat bleeding by providing essential clotting factors (II, VII, IX, and X). It is mainly used to quickly reverse the effects of blood thinners like warfarin in emergencies when there is severe bleeding or before surgery. Pro-Throm Injection is also helpful for patients with haemophilia, liver disease, or vitamin K deficiency, as it replaces missing clotting factors and helps control bleeding. Additionally, it can be used to manage bleeding in conditions like disseminated intravascular coagulation (DIC).

How Pro-Throm Injection Works

Pro-Throm Injection contains clotting factors (Factor II, Factor VII, Factor IX, Factor X), which work by replenishing vitamin K-dependent coagulation factors and antithrombotic proteins to restore normal blood clotting and prevent excessive bleeding.

Storage

• Store in a cool and dry place away from sunlight.• Keep Pro-Throm Injection out of the sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Pro-Throm Injection
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

What if I have taken an overdose of Pro-Throm Injection

Pro-Throm Injection is a parenteral formulation. Hence, the chance of overdose may be less. However, keep track of your medicine as an overdose of Pro-Throm Injection may cause serious side effects. Seek immediate medical attention if you observe any unpleasant side effects.

Drug Warnings

Do not take Pro-Throm Injection if you are allergic to its components or have conditions like disseminated intravascular coagulation or heparin-induced thrombocytopenia. Inform your doctor about any history of thromboembolic events, seizures, or liver/kidney impairments. Talk with your doctor if you have had a heart or blood vessel-related event within the past 3 months, including a heart attack, stroke, transient ischemic attack, unstable angina, severe peripheral vascular disease, or blood clots. Consult your doctor if you are pregnant or breastfeeding. Pro-Throm Injection's safety and efficacy in children are unknown. Keep your doctor updated on your health and medications to minimize side effects and interactions.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat a balanced diet rich in vegetables and whole fruits.
  • Include green leafy vegetables, soybean and canola oil, and fortified meal replacement shakes.
  • Avoid smoking and alcohol consumption.
  • Avoid processed and fried food.
  • Exercising regularly helps in improving overall health.
  • Rest well, and get plenty of sleep.
  • Meditation and yoga can help lower stress.

Habit Forming

No

Therapeutic Class

HEMOSTATIC AGENTS
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Alcohol

Caution

It is not known if alcohol interacts with Pro-Throm Injection. Please consult your doctor if you have any concerns. However, avoid alcohol to prevent unpleasant reactions.

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Pregnancy

Caution

Inform the doctor if you are pregnant. Your doctor will prescribe it only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before receiving Pro-Throm Injection while breastfeeding, as it's unclear if the medication passes into breast milk.

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Driving

Consult your doctor

The effect of Pro-Throm Injection on driving or operating heavy machinery is unknown. Drive or operate machinery only if you feel alert.

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Liver

Safe if prescribed

Please consult the doctor if you have liver impairments or diseases. The doctor may suggest it only if the benefits outweigh the risks.

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Kidney

Caution

If you have kidney impairments, inform your doctor before taking Pro-Throm Injection. The doctor may suggest it only if the benefits outweigh the risks.

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Children

Consult your doctor

Consult a doctor before giving Pro-Throm Injection to children, as its safety and effectiveness in children have not been established.

FAQs

Pro-Throm Injection is used to prevent and treat bleeding. It is mainly used to rapidly reverse anticoagulation caused by blood thinners like warfarin during severe bleeding or when emergency surgery or invasive procedures are required.

Pro-Throm Injection works by replenishing vitamin K-dependent coagulation factors and antithrombotic proteins, restoring normal blood clotting and preventing excessive bleeding.

Yes, Pro-Throm Injection is effectively used in the prevention and treatment of bleeding.

Pro-Throm Injection is administered by a healthcare professional through an intravenous (IV) infusion. Do not self-administer.

Yes, Pro-Throm Injection is usually a safe and well-tolerated medication. However, it may cause side effects such as headache, nausea, vomiting, and dizziness.

The common side effects of Pro-Throm Injection may include headache, nausea, vomiting, and dizziness. Most of these side effects do not require medical attention and gradually resolve over time. However, if they persist or worsen, please consult your doctor.

Please consult your doctor if you are pregnant or breastfeeding before taking Pro-Throm Injection, as its effects on pregnancy and breastfeeding are not well known. Your doctor will suggest it only if the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PRO2486

Disclaimer

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Reference

  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC2906185/
  2. https://www.medicines.org.uk/emc/files/pil.7958.pdf
  3. https://www.fda.gov/media/85512/download
  4. https://www.intaspharma.com/wp-content/uploads/2021/12/Pro-throm-PIL-AW-047-02.pdf

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