Prekit-DM 75/30 Capsule 10's

This combination may be prescribed for different types of nerve-related pain, depending on the underlying condition and your doctor's assessment:

• Diabetic neuropathy: Helps relieve the burning, stabbing, or shooting nerve pain in the hands and feet caused by chronic high blood sugar.
• Postherpetic neuralgia: Eases the persistent, severe nerve pain that lingers long after a shingles rash has healed.
• Fibromyalgia: Reduces widespread muscle pain, tenderness, and fatigue by stabilising overactive pain signals in the central nervous system.
• Spinal cord injury pain: May be considered in certain cases of nerve pain following spinal cord injury, but this specific fixed-dose combination is not a standard treatment for all patients and should be used only when determined appropriate by your doctor.

By combining medicines that reduce abnormal pain signalling with vitamin B12 support, this treatment may provide several benefits for people experiencing persistent nerve pain:

• Effective Nerve Pain Relief: It significantly reduces the intensity of sharp, burning, or electric-shock-like sensations, allowing you to focus on your daily activities.
• Restful Sleep: Nerve pain often peaks at night, disrupting sleep. By calming hyperactive nerves, this medicine helps you sleep more comfortably.
• Improved Mobility: Easing chronic pain makes simple movements, light walking, and daily physical tasks much easier to perform.
• Nerve Health Support: Methylcobalamin provides vitamin B12, which supports normal nerve function and myelin maintenance, particularly when adequate vitamin B12 is required.

• Prekit-DM 75/30 Capsule 10's can be taken with or without food or as advised by your doctor.
• Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
• Swallow Prekit-DM 75/30 Capsule 10's as a whole with a glass of water.
• Do not crush break or chew it.

• Manage blood sugar: If you have diabetes, monitor your blood glucose regularly and follow your prescribed diabetes treatment, as good glucose control can help reduce the risk of further nerve damage.
• Stay physically active: Include suitable low-impact activities such as walking, swimming, or gentle stretching to maintain mobility and support overall circulation.
• Avoid alcohol: Avoid or limit alcohol as advised by your doctor, as excessive alcohol can worsen nerve damage and may increase dizziness and drowsiness when combined with this medicine.
• Protect your feet: Wear comfortable, well-fitting footwear and check your feet regularly for cuts, blisters, redness, or sores that may go unnoticed because of reduced sensation.
• Maintain a balanced diet: Include nutritious foods containing B vitamins, such as eggs, lean meats, dairy products, legumes, and green leafy vegetables, as part of a balanced diet that supports overall nerve and general health.

• Do not stop suddenly: Do not stop taking Prekit-DM 75/30 Capsule 10's without medical advice. Your doctor may gradually reduce the dose to minimise withdrawal or discontinuation symptoms.
• Take care with driving: Avoid driving, cycling, or operating machinery until you know how the medicine affects you, as dizziness, sleepiness, or reduced concentration may occur.
• Monitor your mood: Contact your doctor promptly if you notice significant mood changes, worsening anxiety, unusual behaviour, or thoughts of self-harm.
• Tell your doctor about other medicines: Inform your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take, as some may interact with duloxetine or pregabalin.
• Avoid alcohol: It is best to avoid alcohol during treatment, as it can increase dizziness and drowsiness and may add to the risk of liver problems associated with duloxetine
• Important mood warning: Duloxetine, an antidepressant, may increase the risk of suicidal thoughts and behaviours, particularly in children, adolescents, and young adults. Contact your doctor promptly if you notice significant changes in mood or behaviour, worsening depression, or thoughts of self-harm.