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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pregabanyl-Plus Capsule is a combination medicine used in the treatment of neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset.
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Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregabanyl-Plus Capsule

Pregabanyl-Plus Capsule is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damage to sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

Pregabanyl-Plus Capsule contains Pregabalin, mecobalamin, alpha-lipoic acid, folic acid and pyridoxine. Pregabalin works by binding to the specific site on voltage-gated calcium channels, this helps relieve nerve pain and lowers the risk of seizures. Mecobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregabanyl-Plus Capsule helps in providing relief from neuropathic pain.

You are advised to take Pregabanyl-Plus Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, dry mouth and oedema. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Pregabanyl-Plus Capsule without consulting your doctor as it could cause withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Pregabanyl-Plus Capsule causes drowsiness and dizziness, so drive only if you are alert. Pregabanyl-Plus Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabanyl-Plus Capsule as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pregabanyl-Plus Capsule

Pregabanyl-Plus Capsule is used in the treatment of Neuropathic pain. The detailed uses of Pregabanyl-Plus Capsule are as follows:<br/>• Diabetic Neuropathy: Pregabanyl-Plus Capsule helps relieve burning, tingling, and numbness in the limbs caused by diabetes-related nerve damage.<br/>• Peripheral Neuropathy: Pregabanyl-Plus Capsule is used in various conditions where nerves outside the brain and spinal cord are damaged.<br/>• Sciatica & Radiculopathy: Pregabanyl-Plus Capsule eases nerve pain radiating from the spine to the legs or arms.<br/>• Post-Herpetic Neuralgia: Pregabanyl-Plus Capsule manages lingering nerve pain after shingles.<br/>• Vitamin B Deficiency–Related Neuropathy: Pregabanyl-Plus Capsule replenishes essential B vitamins to support nerve repair and function.<br/>

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Directions for Use

• Pregabanyl-Plus Capsule can be taken with or without food, or as advised by the doctor. • Follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness. • Swallow Pregabanyl-Plus Capsule as a whole with a glass of water. • Do not crush, chew, or break Pregabanyl-Plus Capsule , as this may impact absorption.

Medicinal Benefits

Pregabanyl-Plus Capsule is a combination of five drugs: Pregabalin, mecobalamin, alpha-lipoic acid, folic acid and pyridoxine. Pregabanyl-Plus Capsule is used to treat neuropathic pain. Pregabalin is an anti-convulsant that affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels, this helps relieve nerve pain and lowers the risk of seizures. Mecobalamin is a vitamin that helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Pyridoxine (Vitamin B6) is also very useful in facilitating myelin and neurotransmitter synthesis. Alpha-lipoic acid is an antioxidant that helps in providing a protective effect on the nerve tissues and brain. Folic acid is a vitamin that helps in providing essential nutrients to the nerves. Together, Pregabanyl-Plus Capsule helps in providing relief from neuropathic pain.  Additionally, Pregabanyl-Plus Capsule may also be used to treat diabetic neuropathy, fibromyalgia and postherpetic neuralgia.

How Pregabanyl-Plus Capsule Works

Pregabanyl-Plus Capsule contains Pregabalin, mecobalamin, alpha-lipoic acid, folic acid and pyridoxine. Pregabalin works by binding to the specific site on voltage-gated calcium channels, this helps relieve nerve pain and lowers the risk of seizures. Mecobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregabanyl-Plus Capsule helps in providing relief from neuropathic pain.

Storage

• Store in a cool and dry place away from sunlight.
• Store at temperatures not exceeding 25 degrees C. Protect from heat and moisture.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pregabanyl-Plus Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.
  • Perform balance exercises like heel raises, standing on one leg, and weight shifts with the guidance of a physical therapist.
  • Focus on strengthening leg muscles and core muscles for better stability.
  • Stay hydrated by drinking plenty of water as dehydration may lead to unsteadiness and dizziness.
  • Wear low-heeled shoes with good tread for better grip.
  • Change your surroundings by removing tripping hazards like clutter, loose rugs and poorly lit areas.
  • Avoid sudden position changes; stand up slowly and take your time to move around.
  • Watch out for rapid head movements that might trigger dizziness.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

What if I have taken an overdose of Pregabanyl-Plus Capsule

Never take more than the recommended dose. An overdose of Pregabanyl-Plus Capsule may cause symptoms like sleepiness, confusion state, agitation, restlessness, nausea, rashes and itching. Seek immediate medical help in case of accidental overdose.

Drug Warnings

Do not take Pregabanyl-Plus Capsule if you are allergic to any of its contents. Inform your doctor before taking Pregabanyl-Plus Capsule if you have or had heart problems or bipolar syndrome. Please do not stop taking Pregabanyl-Plus Capsule without consulting your doctor as it could cause withdrawal symptoms. Consult your doctor before starting Pregabanyl-Plus Capsule if you are pregnant or breastfeeding. Pregabanyl-Plus Capsule may cause drowsiness and dizziness, so drive only if you are alert. Pregabanyl-Plus Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabanyl-Plus Capsule as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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PregabalinHydromorphone
Severe
PregabalinPethidine
Severe

Drug-Drug Interactions

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PregabalinHydromorphone
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregabanyl-Plus Capsule:
Taking Ketamine with Pregabanyl-Plus Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabanyl-Plus Capsule and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregabanyl-Plus Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinEsketamine
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
When Pregabanyl-Plus Capsule and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabanyl-Plus Capsule and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregabanyl-Plus Capsule:
Using Pregabanyl-Plus Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregabanyl-Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregabanyl-Plus Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregabanyl-Plus Capsule if you are breastfeeding; your doctor will decide whether Pregabanyl-Plus Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Pregabanyl-Plus Capsule may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pregabanyl-Plus Capsule should not be given to children as the safety and efficacy have not been established.

FAQs

Pregabanyl-Plus Capsule is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damage to sensory nerves.

Pregabanyl-Plus Capsule contains Pregabalin, mecobalamin, pyridoxine, alpha-lipoic acid and folic acid. Pregabalin works by binding to the specific site on voltage-gated calcium channels, this helps in relieving nerve pain. Mecobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregabanyl-Plus Capsule helps in providing relief from neuropathic pain.

Pregabanyl-Plus Capsule is used to treat diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly causes pain in legs and feet.

Pregabanyl-Plus Capsule may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Pregabanyl-Plus Capsule may be used to treat fibromyalgia. Fibromyalgia is a condition which is characterised by musculoskeletal pain, tenderness, fatigue, sleep and mood issues.

Do not discontinue Pregabanyl-Plus Capsule without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Pregabanyl-Plus Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Pregabanyl-Plus Capsule .

Dry mouth could be a side-effect of Pregabanyl-Plus Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Country of origin

INDIA

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116
Other Info - PRE0707

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