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compositionComposition:CYTARABINE-100MG
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Precitar 100mg Injection is an anticancer medicine used to treat leukemia (blood cancer). It contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in cancer cells, which is essential for cell growth, repair, and multiplication. Thus, It stops the multiplication of abnormal cells, leads to the development of cells in an unbalanced way and causes the death of cells.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYTARABINE-100MG

Manufacturer/Marketer :

Premedium Pharmaceuticals

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Precitar 100mg Injection

Precitar 100mg Injection is a prescription injection used to treat certain types of blood cancers, such as acute myeloid leukaemia and acute lymphocytic leukaemia. It is also used to treat or prevent cancer that has spread to the tissues covering the brain and spinal cord. This medicine works by targeting and stopping the growth of abnormal cancer cells in the body.

Because this medicine is given as an injection, a healthcare professional will give it to you in a hospital or clinic setting. The frequency of your treatment will depend on your specific condition and how well your body responds. Since it is given by injection, you do not need to worry about taking it with or without food, but staying well-hydrated before your appointments can help. Eating small, frequent, bland meals and avoiding raw foods can support your recovery during treatment.

Like all cancer treatments, Precitar 100mg Injection can cause some unwanted effects, such as nausea, temporary hair loss, or mouth sores. These are common and usually manageable, but you must contact your doctor immediately if you experience signs of infection, like a fever or chills.

Do not take this if you have had a severe allergic reaction to it in the past. Before starting, talk to your doctor if you have a history of liver damage, kidney disease, or blood disorders, as these conditions may require special monitoring or adjustments to your treatment.

It is important to discuss all other medicines you are taking, as some can increase the risk of side effects when combined with Precitar 100mg Injection. Avoid drinking alcohol and smoking, as they can worsen liver strain and general side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare team immediately, as this medicine can harm an unborn baby.

Uses of Precitar 100mg Injection

Your doctor may prescribe Precitar 100mg Injection to treat the following conditions:

  • Acute Myeloid Leukaemia (AML): Precitar 100mg Injection helps by slowing down or stopping the rapid production of abnormal white blood cells in the bone marrow.
  • Acute Lymphocytic Leukaemia (ALL): This medicine targets and destroys cancer cells that affect your lymphatic system and blood.
  • Meningeal Leukaemia: It is injected directly into the spinal fluid to treat or prevent the spread of leukaemia cells to the brain and spinal cord.

Key Benefits

Precitar 100mg Injection helps control certain blood cancers by slowing the growth and multiplication of abnormal cancer cells. This supports disease control, promotes remission in suitable patients, and allows healthy blood cells to recover during treatment.

  • Helps control blood cancers: Slows the growth and spread of rapidly dividing cancer cells, helping manage conditions such as leukaemia and lymphoma.
  • Supports remission: By reducing the number of abnormal cancer cells, it may help achieve or maintain remission when used as part of an appropriate treatment plan.
  • Allows healthy blood cells to recover: As cancer cells are reduced, the bone marrow can gradually restore the production of normal red blood cells, white blood cells, and platelets.
  • Treats cancer involving the central nervous system: When administered into the spinal fluid (intrathecally), Precitar 100mg Injection delivers treatment directly to the brain and spinal cord, helping control cancer cells in areas that intravenous chemotherapy may not adequately reach.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Precitar 100mg Injection will be administered in the hospital setting by a trained healthcare professional.
  • Do not self-administer.

How Precitar 100mg Injection Works

Precitar 100mg Injection contains cytarabine, which belongs to a group of medicines known as antimetabolites. It is designed to mimic the natural building blocks that your cells use to make DNA. When cancer cells rapidly divide, they absorb Precitar 100mg Injection, thinking it is a normal nutrient they need to grow. Once inside the cancer cells, the medicine interferes with their DNA production and repair processes. Because the cells cannot successfully copy their DNA, they are unable to multiply and ultimately die off. This selective targeting helps reduce the overall number of cancer cells in your blood and bone marrow.
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Alcohol

Unsafe

Avoid consumption of alcohol with Precitar 100mg Injection as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Precitar 100mg Injection. You should not become pregnant while on treatment with Precitar 100mg Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Precitar 100mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Precitar 100mg Injection causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Precitar 100mg Injection.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Precitar 100mg Injection. It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Precitar 100mg Injection as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Precitar 100mg Injection, combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

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Heart

Caution

Precitar 100mg Injection may be used in patients with heart problems, but only with close medical supervision. It can cause cardiac symptoms like fast or uneven heartbeat and chest pain, so monitoring is essential.

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Geriatrics

Caution

Geriatric patients can receive Precitar 100mg Injection, but it may be more susceptible to side effects like low blood counts and neurotoxicity. Careful dosing and close medical monitoring are essential during treatment.

What if I have taken an overdose of Precitar 100mg Injection

Since your treatment is managed and injected by trained medical staff, an accidental overdose is highly unlikely. If you suspect you have received too much of this medicine or notice sudden, severe side effects, tell your healthcare provider or seek emergency medical attention immediately.

Diet & Lifestyle Advise

  • Practice strict food safety: Because this medicine can lower your white blood cell count, avoid raw or undercooked foods, wash all fruits and vegetables thoroughly, and ensure all dairy products are pasteurized to prevent infections.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys flush out the waste products of destroyed cancer cells and to help manage nausea.
  • Eat soft, bland foods: To prevent mouth sores, opt for soft foods like yogurt, mashed potatoes, and well-cooked vegetables. Avoid spicy, salty, or highly acidic foods.
  • Use a soft toothbrush: Brush your teeth gently with a soft-bristled toothbrush to protect your gums from bleeding when your platelet counts are low.
  • Wash your hands frequently: Keep your hands clean and avoid crowded areas or contact with people who are sick to protect yourself from infections.
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How Soon It Starts Working

The time required for Precitar 100mg Injection to start to work: Precitar 100mg Injection ideally shows its action within 15 minutes of administration. The time for which the effects of Precitar 100mg Injection last: Precitar 100mg Injection effect lasts for 12-24 hours.

What if you forget to take Precitar 100mg Injection

Because you will receive this medication under the direct supervision of a healthcare provider, it is unlikely that you will miss a dose. However, if you miss an appointment or need to reschedule, contact your doctor's office immediately to arrange a new time. Keeping your treatment on schedule is very important for the medicine to work effectively.

Storage

•Unopened vials should be stored at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the injection before use: Before each injection, ensure the solution is clear and free from visible particles. Do not use it if it appears cloudy, discoloured, or if the container is damaged.
  • Rotate injection sites: If you are self-administering subcutaneous injections, change the injection site with each dose to help reduce pain, bruising, and skin irritation.
  • Dispose of needles safely: Always discard used needles and syringes in a puncture-resistant sharps container. Never reuse needles or dispose of them in household waste.
  • Monitor for signs of infection: Check your temperature regularly and contact your doctor immediately if you develop a fever of 38°C (100.4°F) or higher, chills, sore throat, or any other signs of infection.
  • Avoid live vaccines: Do not receive live vaccines during treatment unless your doctor specifically advises you to, as your immune system may not respond normally.
  • Attend regular monitoring: Keep all scheduled appointments for blood tests so your doctor can monitor your blood cell counts, kidney function, liver function, and overall response to treatment.

verifiedApollotooltip
  • Live vaccines: Taking Precitar 100mg Injection while receiving live vaccines may increase your risk of developing a severe infection from the vaccine.
  • Digoxin: Precitar 100mg Injection may lower the absorption of digoxin tablets, making your heart medication less effective.
  • Other chemotherapy drugs: Combining this medicine with other cancer treatments can increase the risk of serious side effects, such as low blood counts and liver strain.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Precitar 100mg Injection when used as directed

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Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Precitar 100mg Injection is used to treat Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.
Precitar 100mg Injection contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Precitar 100mg Injection as it may cause infections.
Precitar 100mg Injection may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Precitar 100mg Injection if you are planning to become pregnant.
Precitar 100mg Injection contains cytarabine as its active component. It is an anticancer medicine which belongs to the class of anti-metabolites.
Precitar 100mg Injection is not considered a vesicant (irritant), but it should be administered carefully to prevent any potential issues.
No, ototoxicity (hearing damage) has not been reported with Precitar 100mg Injection use. However, if you experience any related symptoms, it is important to consult your doctor.
Yes, Precitar 100mg Injection is a cytotoxic (cell-damaging).
Yes, Precitar 100mg Injection may cause hair loss as this is one of its side effects. However, please, consult a doctor if this persists for longer durations.
Precitar 100mg Injection causes side effects such as nausea, vomiting, mouth ulcers, loss of appetite, diarrhoea, dark-coloured urine, confusion, dizziness, stomach pain, weakness, and injection site reactions. These will gradually reduce over time. However, consult a doctor if any of these persists longer.
Precitar 100mg Injection is injected by a healthcare provider into a vein, under the skin, or directly into the spinal fluid. Talk to your doctor to understand which method is right for your specific treatment plan.
Frequent blood tests are necessary to check your blood cell counts, kidney health, and liver function. This helps your medical team adjust your treatment schedule safely. Talk to your doctor for more details.
Some people may feel dizzy, weak, or tired after receiving Precitar 100mg Injection. It is best to avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if you experience these symptoms.
The length and frequency of your treatment cycles depend on your specific type of leukaemia and how your body responds to the medicine. Talk to your doctor to understand your personalised treatment schedule.
You must contact your doctor or seek emergency medical attention immediately if you develop a fever, as it can be a sign of a serious infection due to lowered white blood cells. Talk to your doctor about when to seek urgent care.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - PREC902
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