apollo
logo
0
Select Delivery Location
Prebris-MNT Tablet is a combination medicine used to manage diabetic neuropathy, neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, stomach upset, dizziness, and rash.
Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
coupon
coupon
Extra 10% Off with Bank Offers

More about the Product

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Prebris-MNT Tablet

Prebris-MNT Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Prebris-MNT Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Prebris-MNT Tablet helps to treat neuropathic pain.

Take Prebris-MNT Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Prebris-MNT Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Prebris-MNT Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Prebris-MNT Tablet if you are pregnant or breastfeeding. Prebris-MNT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Prebris-MNT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Prebris-MNT Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Prebris-MNT Tablet

Prebris-MNT Tablet is used in the treatment of Neuropathic pain. The detailed uses of Prebris-MNT Tablet are as follows:

  • Neuropathic Pain: Prebris-MNT Tablet is used to treat diabetic neuropathy, post-herpetic neuralgia (shingles), sciatica, and spinal cord injuries.
  • Fibromyalgia: Prebris-MNT Tablet helps manage widespread pain and fatigue.
  • Peripheral Neuropathy: Prebris-MNT Tablet supports nerve repair and reduces tingling, numbness, and burning sensations.
  • Chronic Pain Syndromes: Prebris-MNT Tablet is used to treat pain, including lower back pain and migraine prevention.

Key Benefits

Prebris-MNT Tablet is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Prebris-MNT Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Prebris-MNT Tablet helps to treat neuropathic pain.

Directions for Use

  • Take Prebris-MNT Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Prebris-MNT Tablet Works

Prebris-MNT Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Prebris-MNT Tablet helps to treat neuropathic pain.
bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Prebris-MNT Tablet as it may increase drowsiness and sleepiness.

bannner image

Pregnancy

Caution

If you're pregnant, don't take Prebris-MNT Tablet unless your doctor tells you to. Please consult your doctor if you have any concerns about this; your doctor will only prescribe if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Prebris-MNT Tablet in breastfeeding/nursing mothers.

bannner image

Driving

Unsafe

Prebris-MNT Tablet causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Prebris-MNT Tablet should not be given to children as the safety and efficacy have not been established.

bannner image

Heart

Caution

Please inform your doctor if you have a history of heart disease before using Prebris-MNT Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

bannner image

Geriatrics

Caution

Prebris-MNT Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Prebris-MNT Tablet .

What if I have taken an overdose of Prebris-MNT Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Prebris-MNT Tablet may include irregular heartbeats, severe drowsiness, vision problems, confusion, hallucinations, agitation, stiff muscles, overactive reflexes, vomiting, feeling hot or cold, feeling like you might pass out, seizures, or coma. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.

  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.

  • Exercising regularly helps to improve overall health and combat pain.

  • Rest well and get plenty of rest.

  • Taking a warm bath can be very relaxing.

  • Avoid smoking and drinking alcohol.

  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.

  • Acupuncture, by stimulating pressure points, can be beneficial.

  • Massages with essential oils can help increase circulation.

Have a query?

How Soon It Starts Working

The time required for Prebris-MNT Tablet to start to work: The time required for Prebris-MNT Tablet to show its action is unknown. The time for which the effects of Prebris-MNT Tablet last: The duration of action for Prebris-MNT Tablet is clinically unknown.

What if you forget to take Prebris-MNT Tablet

If you miss a dose of Prebris-MNT Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Prebris-MNT Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you are allergic to any of the ingredients in Prebris-MNT Tablet , do not consume it. Please do not stop taking Prebris-MNT Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Prebris-MNT Tablet unless your doctor has prescribed it. Prebris-MNT Tablet may cause drowsiness and dizziness, therefore drive only if you are alert. Prebris-MNT Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Prebris-MNT Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Prebris-MNT Tablet may have interaction with antidepressant medications (e.g. duloxetine, sertraline, escitalopram), pain killer medications (e.g. codeine, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant medications (e.g. topiramate), anti-anxiety medications (e.g. alprazolam), sedative-hypnotics medications (e.g. zolpidem), antihistamine medications (e.g. diphenhydramine, cetirizine), muscle relaxant medications (e.g. cyclobenzaprine), antiemetic medications (e.g. ondansetron), and herbal medications to treat depression (e.g. St John's wort).

Drug-Food Interactions: Avoid alcohol consumption while taking Prebris-MNT Tablet as it might cause increased drowsiness and sleepiness.

Drug-Disease Interactions: Use Prebris-MNT Tablet with medical advice if you have had anticholinergic effects, cardiovascular disease, pheochromocytoma, acute myocardial infarction recovery, cardiovascular disease, depression, seizure disorders, drug dependence, suicidal tendency, angioedema, creatine kinase elevations, peripheral oedema, PR interval prolongation, bone marrow suppression, diabetes, renal/liver disease, schizophrenia/bipolar disorder, hyper/hypoglycemia, schizophrenia, thyroid disorders and urinary retention.

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Prebris-MNT Tablet:
Coadministration of Prebris-MNT Tablet with safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in the body).

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and safinamide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Co-administration of Prebris-MNT Tablet with selegiline may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in the body).

How to manage the interaction:
Although there is an interaction between and selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Taking Prebris-MNT Tablet with isocarboxazid may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in the body).

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and isocarboxazid, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Coadministration of Nortriptyline with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between nortriptyline and tranylcypromine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Coadministration of Prebris-MNT Tablet with linezolid may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in the body).

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and linezolid, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Coadministration of Prebris-MNT Tablet with potassium citrate can increase the risk or severity of gastric bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and potassium citrate, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Prebris-MNT Tablet:
Coadministration of nortriptyline with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between nortriptyline and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Prebris-MNT Tablet:
Taking Prebris-MNT Tablet with granisetron may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in the body).

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and granisetron, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Prebris-MNT Tablet:
Coadministration of Prebris-MNT Tablet with fluvoxamine an increase the blood levels and also increase the risk of side effects of Prebris-MNT Tablet.

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and fluvoxamine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sleepiness, ry mouth, blurred vision, constipation, or urinating less than usual. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Prebris-MNT Tablet:
Taking Prebris-MNT Tablet with oxycodone can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Prebris-MNT Tablet and oxycodone, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Prebris-MNT Tablet is used to treat neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia.

Prebris-MNT Tablet contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Prebris-MNT Tablet helps to treat neuropathic pain.

Dry mouth could be a side-effect of Prebris-MNT Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not stop taking Prebris-MNT Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Prebris-MNT Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Prebris-MNT Tablet , do not be afraid to speak with your doctor.

Prebris-MNT Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.

Prebris-MNT Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

Prebris-MNT Tablet is not a painkiller. However, it is a combination medicine used to manage neuropathic pain, particularly in conditions like diabetic peripheral neuropathy and postherpetic neuralgia.

The common side effects of Prebris-MNT Tablet include sleepiness, dizziness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. Most of these side effects do not require medical attention and gradually resolve over time. However, please consult the doctor if these symptoms persist or worsen.

Prebris-MNT Tablet is a medication combination consisting of Methylcobalamin (Vitamin B12), Nortriptyline (Tricyclic Antidepressant), and Pregabalin (Anticonvulsant), commonly prescribed for managing neuropathic pain and nerve damage.

To manage weight gain associated with Prebris-MNT Tablet , maintain a balanced diet rich in fibre and protein while avoiding processed and sugary foods. Engage in regular physical activity, including cardio and strength training, to boost your metabolism. Monitor your weight and consult your doctor if you notice any significant changes.

Yes, Prebris-MNT Tablet may cause sleepiness or dizziness as a common side effect. Therefore, avoid driving or operating heavy machinery unless you are fully alert.

Prebris-MNT Tablet may affect sexual health in some individuals. It may cause side effects such as reduced libido, erectile dysfunction, or difficulty achieving orgasm, mainly due to Nortriptyline and Pregabalin affecting neurotransmitters and nerve function. Please consult the doctor for guidance or alternative treatment options if you experience any changes in your sexual health.

Prebris-MNT Tablet is generally well tolerated, but in very rare cases, it may cause allergic reactions, such as rash, itching, or swelling, and breathing difficulties, especially in individuals with pre-existing lung conditions or when combined with CNS depressants.

Prebris-MNT Tablet starts working as soon as you begin taking it. However, it may take a few weeks to show its complete effects. Therefore, continue taking it as prescribed by the doctor, and please consult your doctor if you have any concerns.

If you forget a dose of Prebris-MNT Tablet , take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose.

If you accidentally overdose on Prebris-MNT Tablet , seek immediate medical attention. Overdose symptoms can be severe and include drowsiness, confusion, vision problems, dizziness, irregular heartbeat, low blood pressure, convulsions, and breathing difficulties. In extreme cases, an overdose can lead to coma or even life-threatening complications. Call your doctor or emergency services right away for urgent treatment.

No, taking a higher dose of Prebris-MNT Tablet than recommended will not necessarily be more effective and may increase the risk of serious side effects. Always follow the dosage instructions provided by your doctor or pharmacist.

Avoid consuming alcohol while taking Prebris-MNT Tablet as it may increase drowsiness or sleepiness. Avoid driving or operating heavy machinery until you know how the medication affects you. Avoid taking other medicines, including herbal supplements and OTC medications, without a doctor’s advice.

While taking Prebris-MNT Tablet , your doctor may recommend regular check-ups based on your medical condition to monitor your response, adjust dosages, and manage potential side effects. Please consult your doctor immediately if you experience any changes in your condition.

Prebris-MNT Tablet should be stored in a cool and dry place, away from sunlight. Keep it out of sight and reach of children.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase 3, New Delhi - 110020.
Other Info - PRE1465
whatsapp Floating Button
Buy Now
Add to Cart