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Written By ,
Reviewed By Veda Maddala , M Pharmacy

Potentox 500 mg/2000 mg Injection is used to treat severe bacterial infections, such as lower respiratory tract infections (infections in the airway and lungs) and febrile neutropenia (fever with a low white blood cell count). It contains Cefepime and Amikacin, which work by killing or preventing the growth of infection-causing bacteria. In some cases, this medicine may cause common side effects such as nausea, vomiting, diarrhoea, and pain or inflammation at the injection site. Before taking this medicine, inform your doctor if you are allergic to any of its components, if you are pregnant or breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Manufacturer/Marketer :

Venus Remedies Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Potentox 500 mg/2000 mg Injection

Potentox 500 mg/2000 mg Injection is used to treat severe bacterial infections. It is primarily used in the treatment of lower respiratory tract infections (LRTIs), such as hospital-acquired pneumonia (which occurs 48 hours after hospital admission) and community-acquired pneumonia (which occurs outside of a hospital). Also, it is used to treat febrile neutropenia. Bacterial infections occur when harmful bacteria multiply either inside or on the body. LRTIs are infections of the airways and lungs. Febrile neutropenia is a condition characterized by a low white blood cell count accompanied by fever.

Potentox 500 mg/2000 mg Injection is a combination of two medicines: Cefepime (a cephalosporin antibiotic) and Amikacin (an aminoglycoside antibiotic). Cefepime works by preventing the formation of bacterial cell walls, while Amikacin works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. Together, these medicines help treat and prevent the spread of bacterial infections.

In some cases, Potentox 500 mg/2000 mg Injection may cause common side effects such as nausea, vomiting, diarrhoea, and pain or inflammation at the injection site. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to consult your doctor if these side effects persist.

Before receiving Potentox 500 mg/2000 mg Injection, inform your doctor if you are allergic to any of its ingredients and to penicillins or other beta-lactam antibiotics. Also, tell your doctor about any other medications you are taking and any existing health conditions to rule out any potential side effects or interactions. Please consult your doctor if you are pregnant or breastfeeding before receiving Potentox 500 mg/2000 mg Injection, as it may harm the baby. You may feel dizzy after receiving Potentox 500 mg/2000 mg Injection, so avoid driving until fully alert. Always complete the entire prescribed course of treatment and do not stop abruptly to prevent the infection from returning or becoming resistant.

Uses of Potentox 500 mg/2000 mg Injection

Potentox 500 mg/2000 mg Injection is used to treat lower respiratory tract infections and febrile neutropenia. The detailed uses of Potentox 500 mg/2000 mg Injection are as follows:<br/>• Treats lower respiratory tract infections: Potentox 500 mg/2000 mg Injection helps manage serious lung infections, including pneumonia acquired in hospitals or the community.<br/>• Treats febrile neutropenia: Potentox 500 mg/2000 mg Injection is used to control infections in patients with low white blood cell counts and fever, reducing the risk of severe complications.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication for effective results.• Potentox 500 mg/2000 mg Injection will be administered by a healthcare professional in a medical setting.• Do not self-administer.

Medicinal Benefits

Potentox 500 mg/2000 mg Injection is a combination of antibiotic medications used to treat severe bacterial infections. It is primarily used in the treatment of lower respiratory tract infections (LRTIs), such as hospital-acquired (occurs 48 hours or more after hospital admission) and community-acquired (occurs outside of a hospital) pneumonia (lung infection). It is also used to treat febrile neutropenia (low white blood cell count with fever). Additionally, Potentox 500 mg/2000 mg Injection is used to treat skin infections caused by drug-resistant bacteria, bone and joint infections, complicated urinary tract infections, stomach infections, abscesses (painful buildup of pus in body tissue or organs), acute bronchitis (inflammation of the breathing tubes), surgical patients with diabetes, traumatic injuries, and sepsis. Potentox 500 mg/2000 mg Injection contains Cefepime and Amikacin. Cefepime works by preventing the formation of bacterial cell walls, while Amikacin inhibits the production of bacterial proteins. Together, these medicines help kill and prevent the spread of infection-causing bacteria.

How Potentox 500 mg/2000 mg Injection Works

Potentox 500 mg/2000 mg Injection is a combination of two medicines: Cefepime (a cephalosporin antibiotic) and Amikacin (an aminoglycoside antibiotic). Cefepime works by preventing the formation of bacterial cell walls. Amikacin works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. Together, these medicines help in treating and preventing the spread of bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Potentox 500 mg/2000 mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Potentox 500 mg/2000 mg Injection

An overdose of Potentox 500 mg/2000 mg Injection is unlikely, as it is a parenteral medication administered by a healthcare professional. Symptoms of an overdose may include nausea, vomiting, skin rash, fever, and scabs. Accidental overdosing could happen if large doses are administered to patients with kidney problems. Other symptoms may include seizures, myoclonus (involuntary twitching), neuromuscular excitability, and encephalopathy (disturbance of consciousness, including hallucinations, confusion, stupor, and coma). If you suspect an overdose or experience any unusual symptoms during treatment with Potentox 500 mg/2000 mg Injection, seek medical attention immediately.

Drug Warnings

Before receiving Potentox 500 mg/2000 mg Injection, inform your doctor if you are allergic to any of its ingredients, penicillins or other beta-lactam antibiotics. Also, inform your doctor about any other medicines you are taking and your health condition to rule out any unpleasant side effects or interactions. Consult your doctor if you are pregnant or breastfeeding before receiving this medication. Potentox 500 mg/2000 mg Injection is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. You may feel dizzy after receiving Potentox 500 mg/2000 mg Injection, so avoid driving until fully alert. Potentox 500 mg/2000 mg Injection should be used cautiously in patients with neuromuscular disorders, such as Parkinson's disease and myasthenia gravis, as it may worsen muscle weakness. Potentox 500 mg/2000 mg Injection should also be used cautiously in elderly patients with kidney problems. Always complete the entire prescribed course of treatment and do not stop abruptly to prevent the infection from returning or becoming resistant.

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Coadministration of BCG vaccine with Potentox 500 mg/2000 mg Injection can reduce its effectiveness.

How to manage the interaction:
Taking Potentox 500 mg/2000 mg Injection with the BCG vaccine can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Co-administration of cidofovir with Potentox 500 mg/2000 mg Injection can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidofovir with Potentox 500 mg/2000 mg Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
CefepimeCholera, live attenuated
Severe
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Taking the cholera vaccine after or along with Potentox 500 mg/2000 mg Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
CefepimeCholera vaccines
Severe
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Taking the cholera vaccine after or along with Potentox 500 mg/2000 mg Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and Cholera vaccines together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Coadministration of Sirolimus with Potentox 500 mg/2000 mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and sirolimus together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience vomiting, irregular urination, swelling, difficulty breathing, muscle pain, weakness, or palpitation, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Coadministration of Potentox 500 mg/2000 mg Injection with Furosemide can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and furosemide together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Coadministration of Potentox 500 mg/2000 mg Injection with Polymyxin B may increase the risk of severe side effects.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Co-administration of Potentox 500 mg/2000 mg Injection with Vecuronium enhances the effects of vecuronium leading to the risk of breathing difficulty.

How to manage the interaction:
Taking Vecuronium with Potentox 500 mg/2000 mg Injection together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Coadministration of Potentox 500 mg/2000 mg Injection and Capreomycin can increase the risk of side effects. Elderly patients, or patients who have a history of kidney problems may be at a higher risk.

How to manage the interaction:
Although taking Potentox 500 mg/2000 mg Injection and Capreomycin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience difficulty breathing, vomiting, irregular urination, sudden weight gain or loss, swelling, muscle cramps, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Potentox 500 mg/2000 mg Injection:
Co-administration of Potentox 500 mg/2000 mg Injection with Suxamethonium enhances the effects of atracurium leading to the risk of breathing problems.

How to manage the interaction:
Although there is a possible interaction between Suxamethonium and Potentox 500 mg/2000 mg Injection, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience shortness of breath, chest discomfort, palpitation, or dizziness, Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the beneficial bacteria in the stomach that help with digestion. Therefore, you are advised to consume foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich foods such as whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid calcium rich foods, as well as grapefruit and grapefruit juice, as they may hinder the absorption of antibiotics.
  • Avoid consuming alcohol and using tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Potentox 500 mg/2000 mg Injection Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Potentox 500 mg/2000 mg Injection. Please consult a doctor.

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Pregnancy

Consult your doctor

Aminoglycosides may cause fetal harm when used in pregnant women. Therefore, if you are pregnant, please take your doctor's advice before receiving Potentox 500 mg/2000 mg Injection. Your doctor may prescribe Potentox 500 mg/2000 mg Injection if the benefits are greater than the risks.

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Breast Feeding

Caution

Potentox 500 mg/2000 mg Injection should be used cautiously in breastfeeding mothers if prescribed by the doctor.

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Driving

Caution

Potentox 500 mg/2000 mg Injection may cause dizziness or blurred vision. Therefore, drive or operate machinery only if alert after receiving Potentox 500 mg/2000 mg Injection.

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Liver

Safe if prescribed

No dosage adjustment is necessary for patients with impaired liver function.

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Kidney

Caution

Potentox 500 mg/2000 mg Injection should be used cautiously in elderly patients with kidney problems. Dose adjustment may be needed in patients with impaired kidney function.

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Children

Safe if prescribed

Potentox 500 mg/2000 mg Injection can be given to children if prescribed by the doctor. Dose adjustment may be required as per the age and weight of the child.

FAQs

Potentox 500 mg/2000 mg Injection is a combination of antibiotic medications used to treat severe bacterial infections. It is primarily used in the treatment of lower respiratory tract infections (LRTIs), such as hospital-acquired (infection occurs 48 hours after hospital admission) and community-acquired (infection occurs outside of a hospital) pneumonia (lung infection). Also, it is used to treat febrile neutropenia.

Potentox 500 mg/2000 mg Injection is a combination of two medicines: Cefepime (a cephalosporin antibiotic) and Amikacin (an aminoglycoside antibiotic). Cefepime works by preventing the formation of bacterial cell walls. Amikacin works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. Together, these medicines help in treating and preventing the spread of bacterial infections.

Potentox 500 mg/2000 mg Injection may cause common side effects such as nausea, vomiting, diarrhoea, and pain or inflammation at the injection site in some individuals. Most of these side effects will resolve gradually over time and do not require medical attention. However, contact your doctor if you experience these side effects persistently.

Yes, Potentox 500 mg/2000 mg Injection may cause dizziness. You are advised not to drive or operate heavy machinery after taking Potentox 500 mg/2000 mg Injection as it may cause dizziness and can affect vision. Drive or operate machinery only if you are alert.

Potentox 500 mg/2000 mg Injection usually starts working soon after its administration. However, it may take a few days to notice a significant improvement in the symptoms.

Aminoglycosides may cause fetal harm when used in pregnant women. Therefore, if you are pregnant, please take your doctor's advice before receiving Potentox 500 mg/2000 mg Injection. It should also be used cautiously when administered to a breastfeeding woman. Always consult your doctor if you are pregnant or breastfeeding before receiving this medication.

Country of origin

India
Other Info - PO80023

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