Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:POSACONAZOLE-40MG
prescription
Prescription Medicine
info
image icons

Posanex Oral Suspension is used to prevent and treat fungal infections. It contains posaconazole which works by inhibiting fungal cell growth and causing cell death. In some cases, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, and cough. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

POSACONAZOLE-40MG

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Posanex Oral Suspension

Posanex Oral Suspension is an oral suspension used to prevent serious fungal infections in people who have very weak immune systems. It is also prescribed to treat specific fungal infections of the mouth and throat, commonly known as thrush.

To make sure this medicine works effectively, you must take it consistently as directed by your healthcare provider. For the suspension form to be absorbed properly by your body, it is essential to take it with a full meal or a liquid nutritional supplement. Eating meals that contain some fat can also help your body absorb the medicine much better.

While taking Posanex Oral Suspension , some people may experience mild side effects like nausea, diarrhea, or headaches. However, you should contact your doctor immediately if you experience signs of liver damage, such as yellowing of your skin or eyes, dark urine, or severe stomach pain.

Before starting this medicine, tell your doctor if you have a history of liver disease, kidney problems, or abnormal heart rhythms. Do not take this if you are allergic to similar antifungal medicines or if you are taking specific medications that can cause serious heart rhythm changes.

This medicine can interact with several other drugs, including certain cholesterol-lowering medicines and blood thinners, which may increase the risk of serious side effects. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to weigh the benefits and risks.

Uses of Posanex Oral Suspension

Posanex Oral Suspension is used to prevent serious fungal infections in people who have very weak immune systems. The detailed uses of Posanex Oral Suspension are as follows:

  • Prevention of fungal infections: It helps protect people with severely weakened immune systems, such as those undergoing chemotherapy or stem cell transplants, from developing life-threatening fungal infections in the lungs or blood.
  • Treating oral thrush: It is used to treat yeast infections in the mouth and throat, especially when other standard antifungal treatments have not been successful.

Key Benefits

Posanex Oral Suspension helps prevent and treat serious fungal infections by stopping the growth of harmful fungi and yeasts. With regular use as prescribed, it helps protect vulnerable individuals from infection, relieves fungal symptoms, and supports recovery during periods of weakened immunity.

  • Protects Against Serious Fungal Infections: By preventing the growth of dangerous molds and yeasts, this medicine provides important protection for people with weakened immune systems who are at increased risk of fungal infections.
  • Relieves Fungal Infection Symptoms: This medicine helps clear fungal infections such as oral thrush, reducing white patches, soreness, and discomfort to make eating and swallowing more comfortable.
  • Supports Recovery During Medical Treatment: By preventing or controlling fungal infections, this medicine helps reduce infection-related complications, allowing you to focus on recovery from conditions such as cancer treatment, organ transplantation, or other therapies that weaken the immune system.
Side effects of Posanex Oral Suspension 105 ml
  • Avoid alcohol as it may be harmful and worsen certain condition.
  • Take nutritional supplements only as advised by your doctor.
  • Limit sodium intake.
  • Consult your doctor for medications to treat your condition effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Posanex Oral Suspension can be taken with meals or within 20 minutes after eating.
  • It is usually taken 1 to 3 times a day, or as prescribed by your doctor.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Shake the bottle well before use. Avoid using regular household spoons, as they may not measure the dose correctly.

How Posanex Oral Suspension Works

Posanex Oral Suspension contains posaconazole, which works by disrupting the way fungi build their protective outer structures. Fungi need a specific compound called ergosterol to keep their cell walls strong and intact. Without a stable cell wall, the fungi cannot survive, grow, or spread throughout your body. This medicine blocks the specific process that the fungus uses to manufacture ergosterol. As a result, the fungal cell walls weaken and break open, which kills the fungus or stops it from multiplying. This allows your body's natural defence systems to successfully clear the infection.
bannner image

Alcohol

Consult your doctor

The interaction of Posanex Oral Suspension with alcohol is unknown. If you have any concerns regarding this, please discuss with your doctor.

bannner image

Pregnancy

Consult your doctor

Posanex Oral Suspension should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posanex Oral Suspension .

bannner image

Breast Feeding

Consult your doctor

There is no substantial research yet on using Posanex Oral Suspension in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Posanex Oral Suspension ; your doctor will decide whether Posanex Oral Suspension can be taken by breastfeeding mothers.

bannner image

Driving

Caution

It is unknown whether Posanex Oral Suspension alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

bannner image

Liver

Consult your doctor

Inform your doctor before taking the Posanex Oral Suspension if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Consult your doctor

Inform your doctor before taking the Posanex Oral Suspension if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Consult your doctor

Please consult a doctor before using Posanex Oral Suspension for children.

bannner image

Heart

Caution

Posanex Oral Suspension should be used cautiously in people with heart problems, as it may affect heart rhythm and cause QTc prolongation. Always consult your doctor before use, especially if you're on cardiac medications or have a history of arrhythmias.

bannner image

Geriatrics

Caution

Posanex Oral Suspension is generally safe for geriatric patients, with no dosage adjustment needed based on age alone. However, older adults should still consult their doctor before use, especially if they have liver issues or take multiple medications.

What if I have taken an overdose of Posanex Oral Suspension

If you take too much of this medicine, seek immediate medical attention or contact a nearby medical centre right away.

Diet & Lifestyle Advise

  • Eat with your dose: Pair each dose with a high-fat meal or a nutritional shake to significantly improve how much medicine enters your bloodstream.
  • Avoid grapefruit: Do not consume grapefruit or grapefruit juice while taking this medicine, as it can interfere with how your body processes the drug.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience mild diarrhoea, to keep your fluids balanced.
  • Practice gentle oral care: Use a soft-bristled toothbrush and avoid harsh mouthwashes if you are treating oral thrush to prevent irritating sensitive tissues.
health query

Have a query?

How Soon It Starts Working

The time required for Posanex Oral Suspension to start to work: Posanex Oral Suspension ideally shows its action within few hours after application. The time for which the effects of Posanex Oral Suspension last: The duration of action for Posanex Oral Suspension is unknown.

What if you forget to take Posanex Oral Suspension

If you miss a dose, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Posanex Oral Suspension oral suspension at room temperature, ideally between 15°C and 30°C (59°F to 86°F).•Keep the bottle tightly closed when not in use.

Drug Warnings

  • Shake the oral suspension bottle vigorously before measuring each dose.
  • Always use the spoon or cup provided in the packaging; never guess or use household spoons.
  • Take each dose with food or a nutritional drink; taking it on an empty stomach can make it much less effective.
  • Complete the full course of treatment prescribed by your doctor, even if you start feeling better.
  • Tell your doctor about all other medicines you take, including over-the-counter drugs and herbal supplements, before starting Posanex Oral Suspension .

Drug-Drug Interactions

verifiedApollotooltip
  • Cholesterol-Lowering Medicines (Statins): Taking Posanex Oral Suspension together with certain statins may increase the risk of serious muscle problems, including muscle pain, weakness, or, rarely, muscle breakdown (rhabdomyolysis). Your doctor may adjust your treatment or monitor you more closely.
  • Blood Thinners: Posanex Oral Suspension may interact with blood-thinning medicines, increasing the risk of bleeding. Inform your doctor if you are taking medicines such as warfarin or other anticoagulants so appropriate monitoring can be arranged.
  • Heart Medicines: Certain medicines used to treat heart conditions may interact with Posanex Oral Suspension and increase the risk of serious heart rhythm disturbances. Your doctor may recommend dose adjustments or regular heart monitoring if these medicines are used together.
PosaconazoleEliglustat
Critical
PosaconazoleSimvastatin
Critical

Drug-Drug Interactions

Login/Sign Up

PosaconazoleEliglustat
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking eliglustat with Posanex Oral Suspension 105 ml can increase the levels of eliglustat in the blood.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.
PosaconazoleSimvastatin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking Posanex Oral Suspension 105 ml with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posanex Oral Suspension 105 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleTicagrelor
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Co-administration of Posanex Oral Suspension 105 ml with Ticagrelor can increase the risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Posanex Oral Suspension 105 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
PosaconazoleIvabradine
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Using ivabradine together with Posanex Oral Suspension 105 ml may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Posanex Oral Suspension 105 ml together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
PosaconazoleCisapride
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
When Posanex Oral Suspension 105 ml is taken with Cisapride, it can lower the rate at which Cisapride is broken down in the body.

How to manage the interaction:
Taking Posanex Oral Suspension 105 ml with Cisapride is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PosaconazoleSaquinavir
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking saquinavir together with Posanex Oral Suspension 105 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and saquinavir, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazolePimozide
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking pimozide with Posanex Oral Suspension 105 ml can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleSilodosin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Coadministration of silodosin and Posanex Oral Suspension 105 ml may significantly increase the blood levels and effects of silodosin.

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.
PosaconazoleLovastatin
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Taking lovastatin with Posanex Oral Suspension 105 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Lovastatin and Posanex Oral Suspension 105 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
PosaconazoleEplerenone
Critical
How does the drug interact with Posanex Oral Suspension 105 ml:
Coadministration of Posanex Oral Suspension 105 ml with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between Posanex Oral Suspension 105 ml and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food or Nutritional Drinks: Always take Posanex Oral Suspension with food or a nutritional drink, as taking it on an empty stomach significantly reduces its absorption and makes the medicine less effective.
  • Grapefruit and Grapefruit Juice: Avoid grapefruit and grapefruit juice while taking Posanex Oral Suspension , as they can affect how your body processes the medicine, leading to altered drug levels and an increased risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Posanex Oral Suspension is used to treat fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.
Posanex Oral Suspension contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Posanex Oral Suspension is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanex Oral Suspension .
Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Posanex Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
You should avoid taking Posanex Oral Suspension on an empty stomach. The oral suspension must be taken with a full meal or a nutritional drink to be absorbed properly by your body. Talk to your doctor or pharmacist if you struggle to eat.
If you cannot eat a full meal, you can take Posanex Oral Suspension with a liquid nutritional supplement or an acidic carbonated beverage like ginger ale. Talk to your doctor or pharmacist for specific advice.
Yes, in some cases, Posanex Oral Suspension can cause liver issues. Your doctor will likely perform regular blood tests to monitor your liver health while you are on this medicine. If you notice yellow skin or eyes, contact your doctor immediately.
The duration of treatment depends entirely on your medical condition and risk factors. Always complete the entire course prescribed by your doctor, even if you feel better.
It is best to avoid alcohol while taking Posanex Oral Suspension . Alcohol can increase the risk of side effects like nausea and dizziness, and it can place extra stress on your liver. Talk to your doctor for personalised advice.
If you vomit shortly after taking your dose, do not take another dose right away. Contact your doctor or pharmacist to find out if you need to take an extra dose or wait until your next scheduled time.
Posanex Oral Suspension is generally not recommended during pregnancy unless the benefits clearly outweigh the risks. If you are pregnant or planning to become pregnant, talk to your doctor before starting this medicine.
Certain medicines that reduce stomach acid, like proton pump inhibitors, can significantly lower how much Posanex Oral Suspension your body absorbs. Talk to your doctor or pharmacist before taking any acid-reducing medicines.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - POS0081
whatsapp Floating Button
Buy Now
Add to Cart