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Polysmile Capsule 10's treats hypertension (high blood pressure) and reduces cholesterol levels. Also, it reduces the risk of heart attack or stroke. It contains Aspirin, Atorvastatin, Metoprolol and Ramipril. Aspirin decreases the formation of harmful blood clots. Atorvastatin decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by lowering the excess cholesterol deposition in the major blood vessels of the brain and heart. Metoprolol makes the heartbeat slowly and with less force. Thus, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Ramipril reduces the production of certain substances in the body that could raise blood pressure. Thus, it lowers blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood around the body.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ASPIRIN-75MG+ATORVASTATIN-10MG+METOPROLOL-25MG+RAMIPRIL-2.5MG

Manufacturer/Marketer :

Tk Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Polysmile Capsule 10's

Polysmile Capsule 10's is a prescription medicine used to reduce the risk of serious cardiovascular events such as heart attacks and strokes. It is typically prescribed for individuals who have existing heart disease or are at high risk of developing blood vessel complications. This medicine combines several protective actions to keep your blood flowing smoothly and your heart working efficiently.

To get the best results, you must take Polysmile Capsule 10's consistently every day at the same time, exactly as prescribed by your doctor. It is generally recommended to take this tablet or capsule with food. To help protect your stomach from irritation. Adopting a heart-healthy diet low in salt and saturated fats, along with regular moderate physical activity, will significantly enhance the benefits of this treatment.

While this medicine is highly effective, some people may experience mild side effects such as a dry cough, dizziness, or mild stomach upset. However, you must contact your doctor immediately if you experience severe symptoms, such as unexplained muscle pain, unusual bleeding, or swelling of the face.

Before starting Polysmile Capsule 10's, tell your doctor if you have a history of asthma, kidney problems, or stomach ulcers. Do not take this if you are currently experiencing active bleeding, have severe liver damage, or are pregnant or planning to become pregnant.

This medicine can interact with alcohol, which increases the risk of stomach bleeding, and smoking, which reduces the drug's heart-protective benefits. Some other medications, including common over-the-counter painkillers, can also affect how it works, so always consult your doctor or pharmacist, especially if you are elderly, pregnant, or breastfeeding.

Uses of Polysmile Capsule 10's

  • Prevention of heart attack and stroke: Polysmile Capsule 10's helps protect your blood vessels from forming dangerous clots while keeping your cholesterol levels in check.
  • Management of long-term heart disease: This medicine reduces the daily workload on your heart, helping to prevent chest pain and lower high blood pressure.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Comprehensive Heart Protection: Polysmile Capsule 10's offers comprehensive protection by addressing multiple cardiovascular risk factors at once.
  • Three Benefits in One Tablet: By combining blood pressure control, cholesterol reduction, and blood-thinning properties into a single daily dose, it simplifies your treatment plan.
  • Supports Daily Treatment Adherence: This convenient approach makes it much easier to stay on track with your medication, ensuring you receive steady, round-the-clock protection.
  • Supports Long-Term Heart Health: Additionally, this treatment helps improve your overall quality of life by reducing the fear and risk of sudden cardiac events.
  • Supports Recovery and Daily Activities: It supports your recovery after a heart procedure and allows you to participate in daily activities and light exercise with greater confidence and physical comfort.

Directions for Use

  • Polysmile Capsule 10's can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Polysmile Capsule 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Polysmile Capsule 10's Works

Polysmile Capsule 10's contains four active ingredients that work together to shield your heart and blood vessels. Each component targets a different aspect of cardiovascular health to provide a combined protective effect. The first component is aspirin, a low-dose blood thinner. It works by stopping platelets (tiny blood cells) from sticking together. This prevents the formation of harmful blood clots that could block blood flow to your heart or brain. The second component is atorvastatin, which belongs to a class of medicines called statins. It works by blocking a specific enzyme in the liver that produces cholesterol. This lowers 'bad' LDL cholesterol and triglycerides and may modestly raise 'good' HDL cholesterol, helping reduce plaque buildup in your arteries. The third component is metoprolol, a beta-blocker. It works by slowing down your heart rate and reducing the force of each heartbeat. This lowers your blood pressure and makes it easier for your heart to pump blood throughout your body. The fourth component is ramipril, an ACE inhibitor. It works by blocking a natural substance in your body that causes blood vessels to tighten. By allowing your blood vessels to relax and widen, it lowers your blood pressure and reduces stress on your heart.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Polysmile Capsule 10's as it may increase tiredness.

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Pregnancy

Caution

Polysmile Capsule 10's is not recommended for use during the last three months of pregnancy unless advised by a doctor, as aspirin taken near the time of delivery may cause bleeding in both mother and baby. Therefore, please inform your doctor if you are pregnant or planning for pregnancy before taking Polysmile Capsule 10's.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Polysmile Capsule 10's as it may be excreted in human milk and cause adverse effects in the baby. Hence, please consult a doctor if you are breastfeeding.

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Driving

Caution

Polysmile Capsule 10's may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Polysmile Capsule 10's.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before taking Polysmile Capsule 10's. Your doctor may adjust the dose if required based on your condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Polysmile Capsule 10's. Your doctor may adjust the dose if required based on your condition.

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Children

Caution

Polysmile Capsule 10's is not recommended for children below 12 years of age unless advised by a doctor.

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Heart

Caution

Polysmile Capsule 10's is commonly prescribed for heart problems like high blood pressure, heart failure, and heart attack prevention. However, it should only be taken under a doctor’s supervision, as it may increase bleeding risk and affect blood pressure and heart rate.

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Geriatrics

Caution

Geriatric patients can take Polysmile Capsule 10's, but only under strict medical supervision. Age-related changes and other medications may increase risks like low blood pressure, bleeding, or kidney issues.

What if I have taken an overdose of Polysmile Capsule 10's

If you accidentally take too much of Polysmile Capsule 10's, seek immediate emergency medical care. An overdose can cause a dangerous drop in blood pressure, an extremely slow heart rate, severe dizziness, or breathing difficulties.

Diet & Lifestyle Advise

  • Avoid grapefruit and grapefruit juice: Grapefruit can interact with the atorvastatin in Polysmile Capsule 10's, leading to an increased risk of severe muscle pain and liver damage.
  • Follow a low-sodium diet: Reducing your salt intake helps lower your blood pressure, allowing the active blood pressure-lowering ingredients to work more effectively.
  • Limit alcohol consumption: Drinking alcohol while taking this medicine increases the risk of stomach irritation, bleeding, and liver damage.
  • Stay hydrated, but monitor potassium: Ramipril can increase potassium levels in your blood. Avoid using salt substitutes containing potassium without consulting your doctor first.
  • Commit to regular, gentle exercise: Activities like walking or swimming can strengthen your cardiovascular system. Always discuss any new exercise routine with your doctor beforehand.
health query

Have a query?

How Soon It Starts Working

The time required for Polysmile Capsule 10's to start to work: The time required for Polysmile Capsule 10's to show its action is unknown. The time for which the effects of Polysmile Capsule 10's last: The duration of action for Polysmile Capsule 10's is unknown.

What if you forget to take Polysmile Capsule 10's

If you miss a dose of Polysmile Capsule 10's, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.

Storage

•Store Polysmile Capsule 10's at room temperature, ideally between 15°C and 30°C (59°F to 86°F).•Keep the medicine in its original packaging to protect it from moisture and direct light.

Drug Warnings

  • Rise slowly: To prevent dizziness or fainting caused by a drop in blood pressure, stand up slowly when rising from a sitting or lying position.
  • Watch for signs of bleeding: Because this medicine contains a blood thinner, monitor yourself for easy bruising, cuts that take a long time to stop bleeding, or blood in your urine or stools.
  • Do not stop taking suddenly: Abruptly stopping metoprolol can cause a rapid, dangerous rise in heart rate or blood pressure. Always consult your doctor before stopping.
  • Inform healthcare providers: Always tell your dentist, surgeon, or any other doctor that you are taking Polysmile Capsule 10's before scheduling any surgery or medical procedure, as you may need to pause treatment temporarily to prevent excessive bleeding.
  • Monitor your heart rate and blood pressure: Keep a home log of your readings to share with your doctor during check-ups.

verifiedApollotooltip
  • Blood thinners (like warfarin or clopidogrel): Combining these with Polysmile Capsule 10's significantly increases your risk of severe bleeding.
  • Pain relievers (NSAIDs like ibuprofen or naproxen): These can reduce the effectiveness of the blood pressure-lowering components and increase the risk of stomach ulcers and kidney damage.
  • Potassium supplements or potassium-sparing diuretics: Taking these with Polysmile Capsule 10's may cause dangerously high potassium levels in your blood.
  • Other blood pressure medicines: Combining these can cause your blood pressure to drop too low, leading to severe dizziness or fainting.

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verifiedApollotooltip
  • Grapefruit and grapefruit juice: This fruit blocks the breakdown of atorvastatin, which can lead to dangerously high levels of the drug in your body and increase the risk of muscle damage.
  • Alcohol: Drinking alcohol can worsen dizziness by lowering your blood pressure further and increasing the risk of stomach bleeding.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Polysmile Capsule 10's is used to treat Hypertension (high blood pressure), Hyperlipidemia (high cholesterol) and prevention of heart attack or stroke.
Polysmile Capsule 10's contains Aspirin, Atorvastatin, Metoprolol and Ramipril. Aspirin is an antiplatelet drug that decreases the formation of harmful blood clots. Atorvastatin decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Metoprolol makes the heart beat slowly and with less force. Thus, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Ramipril works by decreasing the production of certain substances in the body that could raise blood pressure. Thus, it lowers blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood around the body.
Polysmile Capsule 10's may cause dizziness when standing up from sitting or lying position. Therefore, to avoid such effects, standing up slowly from a sitting or lying position is advised.
Polysmile Capsule 10's should be used with caution in diabetic patients as it may increase blood sugar levels. Therefore, if you have diabetes, inform your doctor before taking Polysmile Capsule 10's. Also, regular monitoring of blood sugar levels is recommended while taking Polysmile Capsule 10's.
It is highly recommended to limit or avoid alcohol while taking Polysmile Capsule 10's. Alcohol can increase the risk of stomach bleeding from aspirin and cause a dangerous drop in blood pressure when combined with metoprolol and ramipril. Talk to your doctor if you have concerns about alcohol use.
The dry, persistent cough is a well-known side effect of ramipril, one of the active ingredients in this medicine. It is usually harmless but can be annoying. If the cough becomes bothersome or severe, do not stop taking the medicine; instead, talk to your doctor, who may suggest an alternative.
You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen with Polysmile Capsule 10's without consulting your doctor. These painkillers can increase the risk of stomach ulcers, reduce the blood pressure-lowering effect of the medicine, and harm your kidneys. Talk to your doctor or pharmacist for safe pain relief alternatives.
Unexplained muscle pain, tenderness, or weakness can be a serious side effect related to the atorvastatin component of Polysmile Capsule 10's. Contact your doctor immediately if you notice these symptoms, especially if you also have a fever or dark urine.
No, Polysmile Capsule 10's is not safe to take during pregnancy. The ramipril component can cause serious harm or death to an unborn baby, especially during the second and third trimesters. If you suspect you are pregnant or become pregnant while taking this medicine, contact your doctor immediately. Do not stop taking the medicine on your own unless your doctor tells you to, as suddenly stopping some of its ingredients may increase your risk of heart-related problems.
Grapefruit juice interferes with the enzymes that break down atorvastatin in your body. This can cause the drug to build up to toxic levels, increasing your risk of severe muscle damage and liver problems. It is best to avoid grapefruit products entirely. Talk to your doctor for more dietary advice.
No, you must not stop taking Polysmile Capsule 10's suddenly. This medicine manages long-term cardiovascular health and prevents life-threatening events like heart attacks. Stopping metoprolol abruptly can also cause a dangerous, sudden rise in blood pressure and heart rate. Always talk to your doctor before making any changes.
Polysmile Capsule 10's is usually taken once a day, and your doctor will advise the best time for you. It is often recommended to take it in the morning with food to establish a consistent routine and minimise stomach upset. Talk to your doctor or pharmacist to determine the schedule that works best for you.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.8627 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Aspirin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Health Products Regulatory Authority (HPRA). 2110682.Ppa1633 006 004.81255C1E 7214 44B6 Ac9F Ab05Dcb3D348.000001Lipitor Final Pil.141120 Human Medicine Product Information. Dublin, Ireland: HPRA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. Pllab Dk1312Mertolok. [Accessed on 02 Jun. 2026]Check here
  6. Metoprolol Leaflet. [Accessed on 02 Jun. 2026]Check here
  7. Health Products Regulatory Authority (HPRA). 42878D17 5Cd9 4B2B B9F2 448013114402 Human Medicine Product Information. Dublin, Ireland: HPRA; 2024. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

2/124, I St Floor Shop No.6 North Facing, From West To East, Pallavaram Taluk, Ragava Nagar 2Nd Main Road, Moovarasanpet, Tamil Nadu.
Other Info - POL0642
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