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compositionComposition:CILOSTAZOL-50MG
prescriptionPrescription Medicine
Pletameg-50 Tablet 10's

Pletameg-50 Tablet is used to treat intermittent claudication (pain, tingling, and numbness in the legs). It contains Cilostazol, which works by expanding the veins and reducing the stickiness of the platelets. Therefore, enhancing the blood flow to the lower limbs. This medicine may sometimes cause side effects such as headache, dizziness, diarrhoea, abnormal stool, bleeding, loss of appetite, and rashes. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CILOSTAZOL-50MG

Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pletameg-50 Tablet

Pletameg-50 Tablet is primarily used to treat intermittent claudication (pain, tingling, and numbness in the legs). Intermittent claudication is the pain that occurs in the legs after walking at a specific speed and for a specific amount of time, depending on the seriousness of the condition.

Pletameg-50 Tablet contains cilostazol, which works by expanding the veins and reducing the stickiness of the platelets. Therefore, it enhances the blood flow to the lower limbs.

You may experience headache, dizziness, diarrhoea, abnormal stool, palpitations (racing or skipping a heartbeat), chest pain, bleeding, loss of appetite, and rashes. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Pletameg-50 Tablet or any of its components, please tell your doctor. Pletameg-50 Tablet should not be taken by pregnant, planning to become pregnant, or breastfeeding women. Pletameg-50 Tablet should not be given to people with a bleeding disorder (haemophilia). Pletameg-50 Tablet is not recommended for use in children.

Uses of Pletameg-50 Tablet

Pletameg-50 Tablet used in the treatment of Intermittent claudication (pain, tingling, and numbness in the legs). The detailed uses of Pletameg-50 Tablet are as follows:

  • Improves Symptoms of Intermittent Claudication: Pletameg-50 Tablet is used to reduce leg pain, tingling, numbness, and cramping caused by poor blood circulation during walking, by widening blood vessels and improving blood flow in the legs.
  • Inhibits Platelet Aggregation: Pletameg-50 Tablet prevents blood clots by stopping platelets from sticking together, helping reduce the risk of complications in peripheral artery disease.
  • Enhances Walking Distance: Pletameg-50 Tablet helps to increase the distance a person with intermittent claudication can walk without pain, improving mobility and quality of life.

Key Benefits

  • Pletameg-50 Tablet plays a vital role in preventing the formation of harmful blood clots in your veins by making platelets (clotting agents) stick together.
  • Pletameg-50 Tablet is used to decrease the symptoms of intermittent claudication (pain in the legs that develops when walking and improves when resting that is produced by narrowing of the vein that supplies blood to the legs).
  • Pletameg-50 Tablet works by expanding the veins and reducing the stickiness of the platelets. Therefore, it enhances the blood flow to the legs.
Side effects of Pletameg-50 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Pletameg-50 Tablet should be taken 30 minutes before breakfast and dinner.
  • It is recommended to take Pletameg-50 Tablet twice daily at the same time each day or as advised by your doctor.
  • Swallow Pletameg-50 Tablet as a whole with a glass of water.
  • Do not crush, chew, or beak it.

How Pletameg-50 Tablet Works

Pletameg-50 Tablet belongs to a class of medications called blood thinners or an antiplatelet medications. Pletameg-50 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. Pletameg-50 Tablet works by expanding the veins and reducing the stickiness of the platelets. Therefore, enhancing the blood flow to the lower limbs.
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Alcohol

Caution

You can drink alcohol with Pletameg-50 Tablet . But do not drink too much while taking this medicine. It can increase the risk of stomach bleeding.

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Pregnancy

Consult your doctor

Pletameg-50 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Pletameg-50 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Unsafe

Pletameg-50 Tablet may cause dizziness. So, it is not recommended to drive or operate heavy machinery when you take Pletameg-50 Tablet .

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Liver

Safe if prescribed

Pletameg-50 Tablet is safely given to the liver patients as there have been no published reports of hepatotoxicity. No dosage adjustment is necessary for patients with liver disease.

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Kidney

Caution

Pletameg-50 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Pletameg-50 Tablet is not recommended for children. The safety and effectiveness of Pletameg-50 Tablet have not been established in children.

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Heart

Caution

Pletameg-50 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Pletameg-50 Tablet .

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Geriatrics

Safe if prescribed

Pletameg-50 Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Pletameg-50 Tablet

Take Pletameg-50 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include severe headache, fainting, diarrhoea, dizziness, and fast/irregular heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to a freshly prepared home-cooked meal, and take proper rest, for a speedy recovery.
  • Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it is beneficial to eat them regularly.
  • Take Pletameg-50 Tablet at least half an hour before or two hours after breakfast and dinner.

Have a query?

How Soon It Starts Working

  • The time required for Pletameg-50 Tablet to start to work: The time required for Pletameg-50 Tablet to show its action is unknown. 
  • The time for which the effects of Pletameg-50 Tablet last: The effect of Pletameg-50 Tablet lasts for 12 hours.

What if you forget to take Pletameg-50 Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep this medicine out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are known to be allergic to Pletameg-50 Tablet or any of its components, please tell your doctor.
  • Prolonged use of Pletameg-50 Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising).
  • If you are going to have any surgery, discontinue taking Pletameg-50 Tablet before the surgery.
  • Pletameg-50 Tablet should not be taken in the conditions like heart failure, chest pain, heart attack, and heart surgery.
  • Pletameg-50 Tablet should not be taken if you have an increased risk of bleeding, such as stomach ulcers, stroke, or problems with your eyes, if you have diabetes.
  • Before taking Pletameg-50 Tablet inform your doctor if your blood pressure is not well controlled.
  • This medicine should not be taken in certain conditions if you have severe kidney disease.
  • Pletameg-50 Tablet should not be taken by pregnant women, women planning to become pregnant, or breastfeeding women.
  • It should not be given to people with a bleeding disorder (haemophilia).
  • Pletameg-50 Tablet may cause drowsiness and dizziness; it is advisable to avoid driving unless you are alert.
  • Pletameg-50 Tablet is not recommended for use in children.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Pletameg-50 Tablet may have interaction with other blood thinners (aspirin, clopidogrel, warfarin), antibiotics (erythromycin, clarithromycin, rifampicin), fungal infections medicines (ketoconazole), antacid (omeprazole), blood-pressure-lowering medicines (diltiazem), cholesterol-lowering medicines (lovastatin, simvastatin or atorvastatin), medicines for malaria (halofantrine), medicines for mental illness (pimozide), medicines used for migraine (ergotamine, dihydroergotamine), water pills (hydrochlorothiazide, furosemide).

Drug-Food Interaction: Pletameg-50 Tablet may interact with a large amount of grapefruit juice and St John’s wort plant (used as an antidepressant).

Drug-Disease Interaction:  Pletameg-50 Tablet should not be given to people with a bleeding disorder, liver disease, or heart disease.

CilostazolCisapride
Critical
CilostazolSparfloxacin
Critical

Drug-Drug Interactions

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CilostazolCisapride
Critical
How does the drug interact with Pletameg-50 Tablet:
When Pletameg-50 Tablet is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Cisapride and Pletameg-50 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolSparfloxacin
Critical
How does the drug interact with Pletameg-50 Tablet:
When Pletameg-50 Tablet is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Sparfloxacin and Pletameg-50 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolThioridazine
Critical
How does the drug interact with Pletameg-50 Tablet:
When Pletameg-50 Tablet is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Thioridazine with Pletameg-50 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolZiprasidone
Critical
How does the drug interact with Pletameg-50 Tablet:
When Pletameg-50 Tablet is taken with Ziprasidone, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Ziprasidone and Pletameg-50 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolMesoridazine
Critical
How does the drug interact with Pletameg-50 Tablet:
When Mesoridazine is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Mesoridazine with Pletameg-50 Tablet, is not recommended but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolPimozide
Critical
How does the drug interact with Pletameg-50 Tablet:
When Pletameg-50 Tablet is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Using Pimozide with Pletameg-50 Tablet is not generally advised, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
CilostazolApixaban
Severe
How does the drug interact with Pletameg-50 Tablet:
Coadministration of Pletameg-50 Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Pletameg-50 Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
CilostazolIndinavir
Severe
How does the drug interact with Pletameg-50 Tablet:
Co-administration of indinavir with Pletameg-50 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking indinavir with Pletameg-50 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
CilostazolSaquinavir
Severe
How does the drug interact with Pletameg-50 Tablet:
Co-administration of saquinavir with Pletameg-50 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking saquinavir with Pletameg-50 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, nausea, diarrhea, bleeding. Do not discontinue any medications without consulting a doctor.
CilostazolDiltiazem
Severe
How does the drug interact with Pletameg-50 Tablet:
Co-administration of diltiazem with Pletameg-50 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking diltiazem with Pletameg-50 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, nausea, diarrhea, bleeding. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANT/ANTITHROMBOTIC]

FAQs

Pletameg-50 Tablet consists of the anti-platelet drug (blood thinner) primarily used to treat intermittent claudication (pain, tingling, and numbness in the legs).

Pletameg-50 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Pletameg-50 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. Pletameg-50 Tablet works by expands the veins and reduces the stickiness of the platelets. Therefore, enhancing the blood flow to the lower limbs.

Yes, Pletameg-50 Tablet increases the risk of bleeding. Always be careful while doing activities that may lead to bleeding or an injury. Immediately inform your doctor if you observe any abnormal damaging or bleeding.

Pletameg-50 Tablet decreases your risk of developing blood clots in the veins of your leg, heart, lungs, and brain. You may not feel any change after taking Pletameg-50 Tablet . However, keep taking this Pletameg-50 Tablet as recommended by your doctor as you will still be receiving its full advantages.

Since Pletameg-50 Tablet widens veins, it generally reduces blood pressure. Hence, if you are taking medicines that lower blood pressure, you should be cautious. Taking Pletameg-50 Tablet with other blood pressure-lowering medicines may reduce your blood pressure to very low amounts. Monitor your blood pressure frequently and talk to your doctor if dose adjustment is needed. Pletameg-50 Tablet has also been reported to raise blood pressure and the reason for which is unknown.

Yes, Pletameg-50 Tablet causes blood thinning. It works by preventing platelets (a type of blood cell) from sticking together and forming clots.

Please consult your doctor if Pletameg-50 Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Pletameg-50 Tablet a few days before surgery to avoid the increased risk of bleeding during the procedure.

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

PLOT NO 266, Industrial Area Phase 1, Panchkula, Punjab 134109
Other Info - PLE0139
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