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Plastomet 50 Injection belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis and severe psoriasis.
Plastomet 50 Injection is also used to treat cancer, such as breast cancer, cervical cancer, bladder cancer, ovarian cancer, testicular cancer, lung cancer, head and neck cancer, mycosis fungoides (a type of blood cancer), bone cancer, and advanced-stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).
Plastomet 50 Injection contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time.
Plastomet 50 Injection prevents and stops the growth of cancer cells, thereby helping treat cancer. Plastomet 50 Injection treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.
In some cases, Plastomet 50 Injection may cause side effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, and tingling sensation. Talk to your doctor if you experience any of the side effects persistently.
Do not take Plastomet 50 Injection if you are pregnant or breastfeeding. Inform your doctor about your medications and health condition to rule out any unpleasant side effects.
Plastomet 50 Injection is used to treat autoimmune diseases and certain types of cancer. The detailed uses of Plastomet 50 Injection are as follows:
Unsafe
You are recommended to avoid alcohol consumption while taking Plastomet 50 Injection.
Unsafe
Plastomet 50 Injection may cause serious birth defects. It is not recommended to take Plastomet 50 Injection while you are pregnant.
Unsafe
Plastomet 50 Injection passes into breast milk. Avoid breastfeeding whilst on treatment with Plastomet 50 Injection and for at least 1 week after the last dose.
Caution
Plastomet 50 Injection may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Plastomet 50 Injection affects you.
Caution
Please consult your doctor if you have liver impairment before receiving Plastomet 50 Injection.
Caution
Please consult your doctor if you have kidney impairment before receiving Plastomet 50 Injection.
Caution
The efficacy and safety of Plastomet 50 Injection in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Plastomet 50 Injection in children.
Caution
Plastomet 50 Injection can be used in heart patients and may even provide cardiovascular benefits. However, it should be administered under medical supervision due to potential side effects and drug interactions.
Caution
Plastomet 50 Injection can be used in geriatric patients, but with caution due to increased sensitivity to side effects like liver toxicity and bone marrow suppression. Regular monitoring and dose adjustments are essential to ensure safe use.
Arthritis:
Psoriasis:
Cancer:

Have a query?
The time required for Plastomet 50 Injection to start to work: Plastomet 50 Injection ideally shows its action within 30 to 60 minutes after administration.
The time for which the effects of Plastomet 50 Injection last: The effect of Plastomet 50 Injection lasts for 9 to 30 hours at a low dose and 24 to 45 hours at a high dose.
Drug-Drug Interactions: Plastomet 50 Injection may have interactions with pain killers/NSAIDs, an antineoplastic agent (cisplatin), immunosuppressants (mercaptopurine, azathioprine), antibiotics (tetracycline, chloramphenicol), and anti-inflammatory agents (sulfasalazine), retinoids.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, or chronic liver disease.
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Plastomet 50 Injection acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.
Plastomet 50 Injection works by suppressing the overactive immune system that is responsible for causing psoriasis. Plastomet 50 Injection interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.
Plastomet 50 Injection may affect fertility in men and women. Consult your doctor if you have any concerns regarding this.
Plastomet 50 Injection causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infection, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Plastomet 50 Injection may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary exposure to sunlight or ultraviolet light, such as tanning beds and sunlamps. Wear protective clothing, sunglasses, and sunscreen while going out.
Plastomet 50 Injection works by suppressing the overactive immune system that is responsible for causing psoriasis. Plastomet 50 Injection interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.
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