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  3. Pirox 10 mg Capsule 10's

Pirox 10 mg Capsule 10's, Pack of 10 CapsuleS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Pirox 10 mg Capsule is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It contains Piroxicam, which stops the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Before taking this medicine, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

PIROXICAM-10MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pirox 10 mg Capsule

Pirox 10 mg Capsule belongs to a group of medications called 'Nonsteroidal Anti-inflammatory Drugs (NSAIDs),' used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Osteoarthritis is a degenerative joint disease caused by the breakdown of cartilage (a protective covering) and the underlying bone. Rheumatoid arthritis is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Ankylosing spondylitis is a chronic inflammatory condition that causes stiffness and fusion of the spinal bones (vertebrae).

Pirox 10 mg Capsule contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Pirox 10 mg Capsule exactly as prescribed. Your doctor will decide the dosage and timing of this medication based on your medical condition. In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Do not take Pirox 10 mg Capsule if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs. Pirox 10 mg Capsule can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not take Pirox 10 mg Capsule unless prescribed by the doctor. Pirox 10 mg Capsule increases the chances of stomach ulcers and bleeding, especially in elderly patients. Consult your doctor before taking Pirox 10 mg Capsule if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Pirox 10 mg Capsule , as it can pass into breast milk. Pirox 10 mg Capsule is not recommended for children under 18 years, as its safety and efficacy have not been established. Pirox 10 mg Capsule may cause drowsiness, dizziness, and vision problems, so drive with caution. Avoid consuming alcohol along with Pirox 10 mg Capsule , as it could lead to increased dizziness and drowsiness.

Uses of Pirox 10 mg Capsule

Pirox 10 mg Capsule is used in the treatment of joint pain and inflammation associated with various conditions. The detailed uses of Pirox 10 mg Capsule are as follows:

  • Rheumatoid Arthritis: It helps reduce inflammation and joint damage caused by autoimmune activity.
  • Osteoarthritis: It helps relieve joint pain, inflammation, and stiffness caused by cartilage wear and tear.
  • Ankylosing Spondylitis: It helps alleviate spinal pain and stiffness associated with this chronic inflammatory disease.
  • Menstrual Pain (Dysmenorrhea) Management: It can effectively relieve pain caused by menstrual cramps, providing comfort during menstruation (periods).
  • Postoperative Pain Management: It is often prescribed for the short-term management of pain and inflammation following surgical procedures.

Directions for Use

  • Pirox 10 mg Capsule can be taken with or without food. However, taking it after food may help reduce stomach upset. 
  • It is usually taken 1-2 times daily at the same time each day or as prescribed by your doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, break, or open the medication.

Medicinal Benefits

Pirox 10 mg Capsule belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Pirox 10 mg Capsule is used to relieve symptoms associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, such as stiffness, swelling, and joint pain. Pirox 10 mg Capsule contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Pirox 10 mg Capsule Works

Pirox 10 mg Capsule contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pirox 10 mg Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Pirox 10 mg Capsule

Do not take more than the prescribed dose of Pirox 10 mg Capsule , as it may cause an overdose. The symptoms of an overdose include drowsiness, lack of energy, vomiting, stomach upset, bloody/black/tarry stools, stomach pain, difficulty breathing, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pirox 10 mg Capsule if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs. Pirox 10 mg Capsule may increase the risk of serious heart-related problems, like heart attack and stroke. It may also cause stomach and intestinal bleeding/ulcers. So, inform your doctor if you have any heart or stomach problems before taking Pirox 10 mg Capsule . Avoid taking Pirox 10 mg Capsule if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG), as it can increase your risk of a heart attack or stroke. Consult your doctor before taking Pirox 10 mg Capsule if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Pirox 10 mg Capsule , as it can pass into breast milk. Pirox 10 mg Capsule is not recommended for children under 18 years, as its safety and efficacy have not been established. Pirox 10 mg Capsule may cause drowsiness, dizziness, and vision problems, so drive with caution. Avoid consuming alcohol along with Pirox 10 mg Capsule , as it may increase drowsiness and the risk of stomach bleeding. Inform your doctor before taking Pirox 10 mg Capsule if you have asthma, water retention (oedema), hypertension (high blood pressure), diabetes (high blood sugar), high cholesterol, blood clots, or liver/kidney disease.

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
PiroxicamCidofovir
Critical

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Pirox 10 mg Capsule:
Using ketorolac tromethamine together with Pirox 10 mg Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamCidofovir
Critical
How does the drug interact with Pirox 10 mg Capsule:
Co-administration of Cidofovir with Pirox 10 mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamTinzaparin
Severe
How does the drug interact with Pirox 10 mg Capsule:
Coadministration of Pirox 10 mg Capsule with Tinzaparin can increase the risk of bleeding.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Tinzaparin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, dizziness, weakness, unexpected bruising or bleeding, swelling, vomiting, blood in your stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
PiroxicamRamucirumab
Severe
How does the drug interact with Pirox 10 mg Capsule:
Coadministration of Pirox 10 mg Capsule with Ramucirumab can increase the risk of bleeding.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Ramucirumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamDasatinib
Severe
How does the drug interact with Pirox 10 mg Capsule:
Using Dasatinib together with Pirox 10 mg Capsule may increase the risk of bleeding.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you experience bruising, feeling dizzy or lightheaded, dark or bloody stools, headaches, contact a doctor right away. Do not stop using any medications without talking to a doctor.
PiroxicamTacrolimus
Severe
How does the drug interact with Pirox 10 mg Capsule:
Taking tacrolimus with Pirox 10 mg Capsule may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Pirox 10 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
PiroxicamMeloxicam
Severe
How does the drug interact with Pirox 10 mg Capsule:
Taking Pirox 10 mg Capsule with Meloxicam together can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Pirox 10 mg Capsule and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamEverolimus
Severe
How does the drug interact with Pirox 10 mg Capsule:
Taking Everolimus and Pirox 10 mg Capsule together can increase the risk of kidney problems.

How to manage the interaction:
Although taking Everolimus and Pirox 10 mg Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamFlurbiprofen
Severe
How does the drug interact with Pirox 10 mg Capsule:
Using Pirox 10 mg Capsule together with flurbiprofen may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding and ulceration.

How to manage the interaction:
Although there is a possible interaction between Flurbiprofen and Pirox 10 mg Capsule, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PiroxicamAdefovir dipivoxil
Severe
How does the drug interact with Pirox 10 mg Capsule:
Coadministration of Pirox 10 mg Capsule with Adefovir dipivoxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Pirox 10 mg Capsule with Adefovir dipivoxil together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and consuming a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS
bannner image

Alcohol

Unsafe

Avoid alcohol consumption while taking Pirox 10 mg Capsule , as it may cause increased dizziness and drowsiness. It may also cause an increase in the risk of stomach/intestinal ulcers and bleeding.

bannner image

Pregnancy

Caution

Avoid taking Pirox 10 mg Capsule if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Pirox 10 mg Capsule only if the benefits outweigh the risks. Do not take Pirox 10 mg Capsule in the last 20 weeks of pregnancy, as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

bannner image

Breast Feeding

Unsafe

Pirox 10 mg Capsule can pass into breast milk. So, avoid breastfeeding while taking Pirox 10 mg Capsule . Please consult your doctor if you have any concerns regarding this.

bannner image

Driving

Unsafe

Pirox 10 mg Capsule may cause drowsiness, dizziness, and vision problems. Do not drive or operate heavy machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Pirox 10 mg Capsule should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Pirox 10 mg Capsule should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have a kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Pirox 10 mg Capsule is not recommended for children under 18 years, as its efficacy and safety have not been established.

Have a query?

FAQs

Pirox 10 mg Capsule is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Pirox 10 mg Capsule works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side effect of Pirox 10 mg Capsule . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Pirox 10 mg Capsule for longer durations or high doses as it may cause unpleasant side effects. Do not exceed the dose and duration prescribed by your doctor.

Pirox 10 mg Capsule may increase the risk of heart attack or stroke. Do not use Pirox 10 mg Capsule immediately before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.

Consult your doctor before taking Pirox 10 mg Capsule if you have diabetes, as Pirox 10 mg Capsule might increase your blood sugar levels.

The common side effects of Pirox 10 mg Capsule are diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - PIR0013

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 23, 2025 | 8:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018147s029lbl.pdf
  2. https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/a_v7/SmPc-PIROXICAM.pdf
  3. https://www.medicines.org.uk/emc/files/pil.14311.pdf
  4. https://www.drugs.com/mtm/piroxicam.html
  5. https://medlineplus.gov/druginfo/meds/a684045.html
  6. https://www.medindia.net/doctors/drug_information/piroxicam.htm

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