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  3. Picolex Tablet 10's

Picolex Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Picolex Tablet 10's is used to treat constipation associated with piles, anal fissures, hernia, cardiovascular disorders, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, elderly and bed-ridden patients. It contains Sodium Picosulfate, which prevents the absorption of water in the colon and intestine, thereby stimulating propulsive (pushing forward) activity. This, in turn, promotes the accumulation of water, allowing stool to pass with ease. Thus, it relieves constipation. In some cases, it may cause common side effects such as diarrhoea, abdominal discomfort, pain, or cramps. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

SODIUM PICOSULFATE-10MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Picolex Tablet 10's

Picolex Tablet 10's belongs to the group of medicines called laxatives used to treat constipation associated with piles, anal fissures, hernia, cardiovascular disorders, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, elderly and bed-ridden patients. Constipation refers to infrequent bowel movements, characterised by stools that are often dry, painful, and difficult to pass. 

Picolex Tablet 10's contains Sodium Picosulfate that prevents the absorption of water in the colon/intestine, thereby stimulating the propulsive (pushing forward) activity, which in turn promotes the accumulation of water, providing that stool can pass with ease. Thus, it relieves constipation. 

You can take Picolex Tablet 10's with or without food. You are advised to take Picolex Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects such as diarrhoea, abdominal discomfort, pain, or cramps in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Picolex Tablet 10's for as long as your doctor has prescribed. Drink plenty of fluids (at least 6-8 glasses) while taking Picolex Tablet 10's to prevent dehydration. Do not take Picolex Tablet 10's for more than a week, as it might cause dependency on Picolex Tablet 10's for a bowel movement. Consult your doctor if you experience any sudden changes in bowel habits that persist for more than two weeks. Consult your doctor before taking Picolex Tablet 10's if you are pregnant or breastfeeding. Picolex Tablet 10's should not be given to children as safety and effectiveness have not been established.

Uses of Picolex Tablet 10's

Picolex Tablet 10's is used in the treatment of constipation. The detailed uses of Picolex Tablet 10's are as follows:<br/>• Relief of Constipation: Picolex Tablet 10's is used for short-term treatment of occasional constipation associated with various conditions, such as haemorrhoids (piles), anal fissures, hernia, cardiovascular disorders, pre/post-operative conditions, and in elderly or bed-ridden patients.<br/>• Bowel Cleansing Before Procedures: Picolex Tablet 10's is used to cleanse the bowel before diagnostic or surgical procedures, including colonoscopy, laparoscopy, childbirth, and radiological investigations.<br/>

Directions for Use

  • Picolex Tablet 10's can be taken with or without food.
  • It is usually taken once daily at bedtime or prescribed by your doctor.
  • Swallow Picolex Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

Picolex Tablet 10's belongs to the group of medicines called laxatives used to treat constipation associated with piles, anal fissures, hernia, cardiovascular disorders, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, elderly and bed-ridden patients. Picolex Tablet 10's consists of Sodium Picosulphate, which is a stimulant laxative that prevents the absorption of water in the colonic lumen and stimulates the colon's propulsive activity, thereby promoting water accumulation.

How Picolex Tablet 10's Works

Picolex Tablet 10's consists of Sodium picosulphate that prevents the absorption of water in the colon/intestine, thereby stimulating the propulsive (pushing forward) activity, which in turn promotes the accumulation of water, providing that stool can pass with ease. Thus, it relieves constipation.

Storage

Keep Picolex Tablet 10's out of reach and sight of children.
Side effects of Picolex Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Stay hydrated by drinking plenty of water to maintain electrolyte and fluid balance.
  • Eat a balanced diet with foods rich in electrolytes, like fruits, vegetables, whole grains, and lean proteins.
  • Avoid excessive sweating, like during intense exercise, to reduce electrolyte loss.
  • Manage stress with meditation or deep breathing to minimize its impact on electrolyte and fluid balance.
  • Drink coconut water to restore electrolytes like potassium and sodium.
  • Inform your doctor if you experience severe symptoms like muscle weakness, cramps, or heart arrhythmias.
  • Dehydration would need immediate medical attention if its severe where medical help can save you from crisis.
  • In case the level of dehydration is from mild to moderate, drink plenty of water for an immediate relief.
  • Seek a place where the surrounding temperature is less and try to stay away from heat and humidity.
  • Lie down by keeping a cool and wet towel on your forehead to prevent high temperature in your body to avoid dehydration.
  • Talk to your medical practitioner and use oral rehydrating salts to replace the lost salts from your body.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.

What if I have taken an overdose of Picolex Tablet 10's

Do not take more than the prescribed dose of Picolex Tablet 10's, as it may cause an overdose. Symptoms of an overdose may include diarrhoea, abdominal cramps, and hypokalaemia. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Picolex Tablet 10's if you are allergic to any of its contents or if you have/had or have acute abdominal surgeries (appendicitis), inflammatory bowel disease, bowel obstruction, gastrointestinal perforation or ulceration, severe dehydration, undiagnosed rectal bleeding, acute liver failure, or severe abdominal pain with vomiting and nausea. Drink plenty of fluids (at least 6-8 glasses) while taking Picolex Tablet 10's. Do not take Picolex Tablet 10's for more than a week, as it might cause dependency on Picolex Tablet 10's for a bowel movement. Talk to your doctor if you notice any sudden changes in bowel habits that persist for over 2 weeks. Consult your doctor before taking Picolex Tablet 10's if you are pregnant or breastfeeding. Picolex Tablet 10's should not be given to children under 10 years, as its safety and effectiveness have not been established.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat more natural fiber – Include plenty of fruits, vegetables, whole grains, and pulses in your meals. These add bulk to your stool and help it move more easily through your intestines.
  • Drink enough water every day – Aim to drink at least 6–8 glasses of water per day. Staying well-hydrated helps keep stools soft and easier to pass.
  • Limit processed and low-fibre foods – Cut back on foods like white bread, cheese, fast food, and snacks that lack fibre and can slow digestion.
  • Stay physically active – Engaging in daily movement, such as walking, stretching, or light exercise, helps keep your intestines active and supports regular bowel movements.
  • Create a bathroom routine – Try going to the toilet at the same time every day, especially after meals. This helps train your body to have regular bowel movements.
  • Don’t ignore the urge to go – When you feel the need to have a bowel movement, don’t delay. Waiting can lead to harder, drier stools.
  • Use a healthy toilet posture – When sitting on the toilet, place your feet on a small stool to raise your knees. This position can help you pass stool naturally.
  • Manage stress and rest well – High stress and inadequate sleep can impact your digestion. Try deep breathing, meditation, or other calming routines, and aim for 7–8 hours of sleep each night.

Habit Forming

No

Therapeutic Class

LAXATIVES

Picolex Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol interacts with Picolex Tablet 10's. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor before taking Picolex Tablet 10's if you are pregnant or planning to become pregnant. Your doctor will prescribe you Picolex Tablet 10's if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Picolex Tablet 10's if you are breastfeeding. Your doctor will decide if Picolex Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Safe

Picolex Tablet 10's has negligible influence on your ability to drive.

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Liver

Caution

Please inform your doctor before taking Picolex Tablet 10's if you have liver impairment/liver disease. Picolex Tablet 10's may not be recommended in case of acute liver failure.

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Kidney

Caution

Please inform your doctor before taking Picolex Tablet 10's if you have kidney impairment/kidney disease.

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Children

Unsafe

Picolex Tablet 10's should not be given to children below 10 years, as its safety and effectiveness have not been established.

Have a query?

FAQs

Picolex Tablet 10's is used to treat constipation associated with piles, anal fissures, hernias, cardiovascular disorders, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, and elderly and bedridden patients.

Picolex Tablet 10's consists of Sodium Picosulphate, which is a stimulant laxative. It prevents the absorption of water in the colonic lumen and stimulates the colon's propulsive activity, thereby promoting the accumulation of water.

Do not take Picolex Tablet 10's for more than a week, as it might lead to dependency on Picolex Tablet 10's for a bowel movement. Taking Picolex Tablet 10's for longer durations may also cause dehydration and an imbalance of fluids and salts in the body, which can affect the tightness of muscles in the intestine. If your bowel movements are irregular, even after taking Picolex Tablet 10's for a week, consult your doctor.

Picolex Tablet 10's does not help with weight loss. It does not reduce the absorption of calories or nutrients. Picolex Tablet 10's may cause dehydration, which can lead to a feeling of weight loss. Drink enough liquids to prevent dehydration.

Consult your doctor before taking Picolex Tablet 10's with other medications, as Picolex Tablet 10's may increase the rate of gastrointestinal transit, which could affect the absorption of other orally administered medicines taken simultaneously.

Overuse or prolonged use of Picolex Tablet 10's may cause dehydration. Severe dehydration may cause weakness, tremors, fainting, and blurry vision. Consult your doctor immediately if you experience these symptoms. Drink enough fluids to avoid dehydration.

Diarrhoea might occur if Picolex Tablet 10's is taken in larger doses. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excessive diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - PIC0200

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:41 AM IST

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Reference

  1. https://www.orionlifes.com/product/sodium-picosulphate-10-mg-tablets/
  2. https://assets.hpra.ie/products/Human/23834/LicenseSPC_PA1009-024-001_24052013132046.pdf
  3. https://www.hplbd.com/downloads/Laxante%20Tablet_Insert.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202535lbl.pdf
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