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Pgut-3 Combipack 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It kills bacteria or prevents their growth. Also, it reduces the amount of acid produced in the stomach. It may cause common side effects, such as nausea, diarrhoea, vomiting, stomach pain, taste change, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Spinogen

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Pgut-3 Combipack 1's

Pgut-3 Combipack 1's is an oral combination medicine prescribed to treat Helicobacter pylori (H. pylori) bacterial infections in the stomach and digestive tract. By clearing this infection, it helps heal peptic ulcers and reduces the risk of ulcers returning. This combination works by lowering stomach acid and eliminating the bacteria responsible for ongoing stomach irritation and ulcer formation.

To get the best results, take Pgut-3 Combipack 1's exactly as prescribed by your doctor, usually twice daily. It is generally taken before meals, commonly before breakfast and the evening meal, so the acid-reducing component can work effectively. Most treatment courses last about 7–14 days, depending on your doctor's recommendation and your individual condition.

Some people may experience mild side effects such as a temporary change in taste, mild diarrhea, nausea, or headache. These effects are often temporary and improve after treatment is completed. However, if you develop severe watery diarrhea, persistent stomach cramps, severe skin reactions, or yellowing of the skin or eyes, contact your doctor promptly.

Before starting Pgut-3 Combipack 1's, tell your doctor if you have liver disease, kidney problems, heart rhythm disorders, or a history of allergies to penicillin antibiotics, macrolide antibiotics, or proton pump inhibitors. Your doctor will review your medical history to make sure this treatment is appropriate for you.

Avoid alcohol during treatment, as it may worsen stomach irritation and increase side effects such as nausea or dizziness. If you are pregnant, breastfeeding, elderly, or taking multiple medicines, consult your doctor before starting treatment. Because antibiotic resistance can affect treatment success, your doctor may select this therapy based on local resistance patterns and current treatment guidelines.

Uses of Pgut-3 Combipack 1's

Pgut-3 Combipack 1's is used in the treatment of Peptic ulcer disease. The detailed uses of Pgut-3 Combipack 1's are as follows:

  • Helicobacter pylori (H. pylori) Infection: Pgut-3 Combipack 1's eliminates the specific bacteria responsible for stomach irritation and ulcers, stopping the infection from spreading.
  • Peptic Ulcer Disease: By lowering stomach acid and clearing bacteria, Pgut-3 Combipack 1's allows painful sores in the stomach lining or upper small intestine to heal completely.
  • Chronic Gastritis: It relieves severe inflammation of the stomach lining caused by bacterial overgrowth, reducing persistent stomach pain and bloating.

Key Benefits

Pgut-3 Combipack 1's helps treat H. pylori infection and promote healing of stomach and duodenal ulcers by addressing the underlying cause of the condition. By reducing stomach acid and eliminating the infection, it helps relieve digestive discomfort and supports long-term recovery. Benefits may include:

  • Helps eliminate H. pylori bacteria from the digestive tract.
  • Supports healing of stomach and duodenal ulcers.
  • Reduces stomach acid and helps relieve burning pain and discomfort.
  • Improves symptoms such as indigestion, bloating, and stomach irritation.
  • Helps reduce the risk of ulcer recurrence when the full treatment course is completed.
  • Supports long-term digestive health and recovery.

Directions for Use

  • Take Pgut-3 Combipack 1's 30-60 minutes before food as advised by your doctor.
  • It is advised to take Pgut-3 Combipack 1's as directed by your doctor, at the same time each day for best results.
  • Swallow Pgut-3 Combipack 1's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Pgut-3 Combipack 1's Works

Pgut-3 Combipack 1's contains Pantoprazole, Amoxycillin, and Clarithromycin. • Pantoprazole: It helps reduce the amount of acid produced in the stomach. This relieves symptoms such as heartburn and stomach pain and helps the stomach lining heal. • Amoxycillin: It is an antibiotic that helps kill the bacteria responsible for the infection, helping clear it from the body. • Clarithromycin: It is an antibiotic that helps stop the growth and multiplication of bacteria, supporting the treatment of the infection.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pgut-3 Combipack 1's. Alcohol intake leads to increased production of stomach acid.

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Pregnancy

Consult your doctor

Consult your doctor before taking Pgut-3 Combipack 1's if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Pgut-3 Combipack 1's. Your doctor will decide whether Pgut-3 Combipack 1's can be taken by breastfeeding mothers or not.

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Driving

Caution

Pgut-3 Combipack 1's causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Pgut-3 Combipack 1's if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Pgut-3 Combipack 1's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pgut-3 Combipack 1's should not be given to children as the safety and effectiveness were not established.

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Heart

Caution

Pgut-3 Combipack 1's should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Pgut-3 Combipack 1's.

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Geriatrics

Safe if prescribed

Pgut-3 Combipack 1's is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Pgut-3 Combipack 1's

If you accidentally take more than your prescribed dose, seek medical attention immediately or contact your local poison control center. Symptoms of an overdose may include severe stomach upset, vomiting, or confusion.

Diet & Lifestyle Advise

  • Eat smaller, frequent meals: Choose smaller meals throughout the day to reduce strain on your stomach and help prevent excess acid production.
  • Avoid stomach-irritating foods and drinks: Limit spicy foods, citrus fruits, tomatoes, caffeine, and carbonated beverages, as they can irritate the stomach lining and worsen symptoms.
  • Limit fried and high-fat foods: Avoid greasy, fried, and high-fat meals, as they take longer to digest and may increase acid reflux and stomach discomfort.
  • Avoid smoking: Do not smoke, as nicotine can weaken the valve between the esophagus and stomach and slow the healing of ulcers.
  • Manage stress effectively: Practice stress-relieving activities such as deep breathing, meditation, or walking, as stress can increase stomach acid production and aggravate symptoms.
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How Soon It Starts Working

  • The time required for Pgut-3 Combipack 1's to start to work: The time required for Pgut-3 Combipack 1's to show its action is unknown.
  • The time for which the effects of Pgut-3 Combipack 1's last: The duration of action for Pgut-3 Combipack 1's is unknown.

What if you forget to take Pgut-3 Combipack 1's

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the medicine before use: Check the blister pack before taking the medicine and do not use it if the packaging is damaged.
  • Complete the full course of treatment: Continue taking the medicine for the entire prescribed duration, even if your symptoms improve before finishing the pack. Completing the full course helps improve treatment success and reduces the risk of the infection returning.
  • Do not share your medication: Pgut-3 Combipack 1's has been prescribed specifically for you and should not be given to anyone else.
  • Watch for severe diarrhoea: Contact your doctor if you develop severe watery diarrhoea during treatment or within several weeks after completing treatment. Avoid self treating with antidiarrheal medicines until you have received medical advice, as this may occasionally indicate a serious intestinal infection.
  • Inform healthcare providers before tests or procedures: Tell your doctor, dentist, or other healthcare professionals that you are taking Pgut-3 Combipack 1's before undergoing medical tests or procedures.
  • Attend recommended follow-up testing: Your doctor may recommend a follow-up H. pylori test, usually at least 4 weeks after treatment, to confirm that the infection has been successfully cleared.

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Drug-Drug Interactions

  • Blood thinners (e.g., warfarin): Taking these medicines alongside Pgut-3 Combipack 1's may increase the risk of bleeding and may require closer monitoring.
  • Heart medicines (e.g., digoxin): Pgut-3 Combipack 1's may increase digoxin levels in the body, raising the risk of side effects and toxicity.
  • Certain HIV medicines (e.g., atazanavir): The pantoprazole component may reduce the absorption and effectiveness of these medicines.
  • Gout medicines (e.g., colchicine): Combining these with Pgut-3 Combipack 1's may increase the risk of colchicine toxicity, particularly in older adults and those with kidney problems.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: Consuming grapefruit products while taking Pgut-3 Combipack 1's may increase the levels of certain components in the bloodstream and raise the risk of side effects.
  • Alcohol: Avoid consuming alcohol while taking Pgut-3 Combipack 1's, as it may irritate the stomach lining and worsen side effects such as nausea, dizziness, and stomach discomfort.

Drug-Disease Interactions

  • Myasthenia gravis: Pgut-3 Combipack 1's may worsen muscle weakness and breathing difficulties in patients with this condition.
  • Liver disease: Patients with liver impairment may require closer monitoring or dose adjustments, as the medicine may accumulate in the body.
  • Kidney disease: Reduced kidney function may affect the removal of some components of Pgut-3 Combipack 1's and increase the risk of side effects.
  • Heart rhythm disorders (e.g., QT prolongation): Pgut-3 Combipack 1's may increase the risk of irregular heartbeats in patients with existing heart rhythm abnormalities.

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Habit Forming

No

Therapeutic Class

[ANTIULCERS, GASTROINTESTINAL AGENTS]

FAQs

Pgut-3 Combipack 1's is used in the treatment of peptic ulcer disease caused by infection with a common type of bacteria called Helicobacter pylori (H. pylori). It works by inhibiting the action of the gastric proton pump and preventing the growth of microorganisms.
Speak to your doctor if you do not feel better even after taking Pgut-3 Combipack 1's for 14 days. Do not take Pgut-3 Combipack 1's for longer durations unless prescribed by the doctor.
Pgut-3 Combipack 1's may cause dizziness. Drive only if you are alert, and do not operate machinery if you feel dizzy after taking Pgut-3 Combipack 1's.
Avoid or limit the consumption of alcohol while on Pgut-3 Combipack 1's as it may lead to increased dizziness. Alcohol intake may also lead to excess production of stomach acid, thereby increasing acidity and heartburn.
Diarrhoea might be a side-effect of Pgut-3 Combipack 1's. Drink enough fluids and eat fibre-rich food if you experience diarrhoea after taking Pgut-3 Combipack 1's. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Pgut-3 Combipack 1's contains pantoprazole, which may increase the risk of bone fracture in the hip, spine, or wrist. Recent clinical studies indicated that pantoprazole may affect the absorption of certain nutrients and minerals required for maintaining good bone health, leading to fractures. This mainly occurs in people taking higher doses of Pgut-3 Combipack 1's for longer durations. Inform your doctor before taking Pgut-3 Combipack 1's if you have osteoporosis or if you are already taking corticosteroids.
Dry mouth could be a side effect of Pgut-3 Combipack 1's. Limiting caffeine intake, avoiding smoking, drinking enough water, and chewing sugar-free gum or candy might help stimulate saliva production and thereby prevent dry mouth.
Inform your doctor if you don’t get better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using Pgut-3 Combipack 1's. Your doctor may need to reassess your condition, possibly perform additional tests, and prescribe a different treatment if necessary.
A peptic ulcer is a sore that develops on the lining of your stomach, lower esophagus, or small intestine. It's usually caused by an infection with Helicobacter pylori (H. pylori) bacteria or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Do not use Pgut-3 Combipack 1's if you have a known hypersensitivity to Pgut-3 Combipack 1's. Use Pgut-3 Combipack 1's with caution if you have liver disease, as the antibiotics in Pgut-3 Combipack 1's can affect liver function. Inform your doctor if you have or ever had gastrointestinal bleeding, diabetes, myasthenia gravis (neuromuscular disease), bone fractures, or hypomagnesemia (low levels of magnesium). Also, let your doctor know if you are breastfeeding, pregnant or planning pregnancy.
Take Pgut-3 Combipack 1's 30-60 minutes before food or as advised by your doctor. Swallow it as a whole with a glass of water. But try to take it at the same time each day for better efficacy. Do not crush or chew it.
No, do not stop using Pgut-3 Combipack 1's even if you feel better, as stopping Pgut-3 Combipack 1's early can leave the infection untreated, which could lead to side effects. Therefore, complete the full course of treatment as prescribed by your doctor.
Common side effects of Pgut-3 Combipack 1's include nausea, diarrhoea, vomiting, stomach pain, altered taste, and headache. If any of these side effects persist or worsen, please consult your doctor.
Yes. Most people can continue consuming dairy products while taking Pgut-3 Combipack 1's. Dairy products do not usually interfere significantly with the effectiveness of this treatment. Follow your doctor's instructions regarding meal timing.
Medicines such as ibuprofen or aspirin may irritate the stomach lining and slow ulcer healing. Speak with your doctor before taking additional pain relievers while being treated for an ulcer.
Pgut-3 Combipack 1's is generally used during pregnancy only when your doctor believes the benefits outweigh the potential risks. If you are pregnant, planning a pregnancy, or breastfeeding, discuss your treatment options with your doctor before starting Pgut-3 Combipack 1's.
Yes. Many doctors recommend a follow-up H. pylori test, such as a stool antigen test or urea breath test, usually at least 4 weeks after completing treatment. This helps confirm that the infection has been successfully cleared.

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Country of origin

India

Manufacturer/Marketer address

Near, GSPL Tower, E304, Second Floor Industrial Area, Phase 8, Godrejj, Sahibzada Ajit Singh Nagar, Punjab 160055
Other Info - PGU0004
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