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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pexiol 0.5 Tablet is used to treat the symptoms of Parkinson's disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. It contains Pramipexole, which mimics the action of dopamine, a natural substance found in the brain that helps control body movement. In some cases, you may experience side effects such as sleepiness, nausea, constipation, dizziness, fatigue, hallucinations, dry mouth, muscle spasms, and peripheral oedema (leg swelling due to fluid overload). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

PRAMIPEXOLE-0.5MG

Manufacturer/Marketer :

Ryon Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pexiol 0.5 Tablet

Pexiol 0.5 Tablet belongs to a group of antiparkinson agents or dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults.

Pexiol 0.5 Tablet contains 'Pramipexole' that works by mimicking the action of dopamine, a natural substance found in the brain. This triggers the nerve impulses in the brain that control body movements.

In some cases, you may experience side effects such as sleepiness, nausea, constipation, dizziness, fatigue, hallucinations, dry mouth, muscle spasms, and peripheral oedema (leg swelling due to fluid overload). Talk to your doctor if you experience the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Pexiol 0.5 Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Pexiol 0.5 Tablet

Pexiol 0.5 Tablet is used in the treatment of Parkinson’s disease, Willis-Ekbom disease (restless legs syndrome). The detailed uses of Pexiol 0.5 Tablet are as follows:

  • Parkinson’s Disease Treatment: Pexiol 0.5 Tablet treats symptoms of Parkinson’s disease, such as tremors, stiffness, and slow movement, by mimicking dopamine in the brain, improving motor function and mobility.
  • Restless Legs Syndrome (RLS) Treatment: Pexiol 0.5 Tablet helps to alleviate symptoms of RLS, by reducing uncomfortable sensations and the urge to move the legs, improving sleep and quality of life.

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Directions for Use

  • Take Pexiol 0.5 Tablet with or without food as advised by your doctor.
  • It is advised to take Pexiol 0.5 Tablet 3 times daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Pexiol 0.5 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Pexiol 0.5 Tablet is used to treat the symptoms of Parkinson’s disease, such as tremors, stiffness, muscle spasms, and poor muscle control.
  • It helps restore the balance of dopamine activity in the brain, which is reduced in patients with Parkinson’s disease.
  • Pexiol 0.5 Tablet acts as a dopamine agonist, meaning it binds to and stimulates dopamine receptors, mimicking the natural effects of dopamine.
  • Pexiol 0.5 Tablet improves motor function and coordination, making body movements smoother and more controlled.
  • It is also used to treat moderate to severe Willis–Ekbom disease (restless legs syndrome) by reducing uncomfortable sensations and the urge to move the legs.
  • It helps reduce symptom severity, enhance mobility, and improve quality of life in affected individuals.
  • Pexiol 0.5 Tablet provides effective relief from movement-related symptoms and supports better daily functioning in patients with Parkinson’s disease or restless legs syndrome.

How Pexiol 0.5 Tablet Works

Pexiol 0.5 Tablet contains 'Pramipexole' that works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement. This triggers the nerve impulses in the brain that control body movements.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Pexiol 0.5 Tablet

Do not take more than the prescribed dose of Pexiol 0.5 Tablet as it may cause an overdose. The symptoms of overdose include a fast heart rate. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Pexiol 0.5 Tablet if you are allergic to any of its contents.
  • Talk to your doctor before taking Pexiol 0.5 Tablet if you have kidney problems, hallucinations, dyskinesia (abnormal limb movements), dystonia (inability to keep the neck straight), sleepiness or suddenly falling asleep, psychosis, vision impairment, severe heart or blood vessel disease, or augmentation (symptoms start earlier).
  • Inform your doctor if you experience symptoms such as apathy, anxiety, depression, fatigue, sweating or pain after dose reduction or stopping Pexiol 0.5 Tablet.
  • Pexiol 0.5 Tablet may cause intense urges such as increased sex drive, gambling, overeating and wasting money. Talk to your doctor if you have any concerns.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Pexiol 0.5 Tablet may cause drowsiness and dizziness, do not drive unless you are alert.
  • Pexiol 0.5 Tablet is not recommended for children below 18 years.
  • Avoid consuming alcohol along with Pexiol 0.5 Tablet as it could lead to increased drowsiness and dizziness.
  • Rise slowly from sitting or lying position as Pexiol 0.5 Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pexiol 0.5 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Do not take Pexiol 0.5 Tablet if you are breastfeeding. Pexiol 0.5 Tablet may reduce the production of breast milk. Also, it can pass into breast milk. If taking Pexiol 0.5 Tablet is unavoidable, stop breastfeeding.

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Driving

Unsafe

Pexiol 0.5 Tablet may cause dizziness, sleepiness and hallucinations. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pexiol 0.5 Tablet is not recommended for use in children below 18years.

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Heart

Please consult your doctor before using Pexiol 0.5 Tablet if you have pre-existing heart problems. Your doctor will prescribe Pexiol 0.5 Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giivng Pexiol 0.5 Tablet to geriatric patients. Your doctor will prescribe Pexiol 0.5 Tablet if the benefits outweigh the risks.

FAQs

Pexiol 0.5 Tablet is used to treat Parkinson's disease and Willis-Ekbom disease (restless legs syndrome).

Pexiol 0.5 Tablet works by acting like dopamine and triggering the nerve impulses in the brain that control our body movements, like restless leg syndrome and Parkinson's.

Pexiol 0.5 Tablet may lower the blood pressure than normal, leading to hypotension (low blood pressure), especially during the initial days of treatment. Do not stand up suddenly; rise slowly to avoid a sudden drop in blood pressure. Regularly monitor your blood pressure levels while taking Pexiol 0.5 Tablet.

Dry mouth could be a side effect of Pexiol 0.5 Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevent drying of the mouth.

Pexiol 0.5 Tablet may cause peripheral oedema (swelling of lower legs and hands due to fluid overload). So, avoid sitting or standing for too long.

Country of origin

India
Other Info - PE62041

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