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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Periway Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough. This medicine works by blocking the action of histamine and transmission of nerve signals from the cough centre in the brain to the muscles that produce cough thus reduce cough associated with cold/flu, allergies, and throat irritation. You may experience common side effects like headache, dizziness, numbness, drowsiness, or nausea.

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About Periway Syrup

Periway Syrup is used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.

Periway Syrup is a combination of two drugs: Levodropropizine (cough suppressant) and Chlorpheniramine maleate (antihistamine). Levodropropizine belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Together, Periway Syrup provides relief from dry cough.

Periway Syrup can be taken with/without food or as advised by your doctor. Your doctor will recommend how often you need to take Periway Syrup based on your medical condition. Some people may experience dry mouth, drowsiness, vomiting, blurred vision, constipation, dizziness or tiredness. Most of these side effects of Periway Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Periway Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Periway Syrup. Periway Syrup is not recommended for children below 2 years of age. Periway Syrup may cause dizziness, drowsiness, blurred vision or impaired thinking in some people. Therefore, drive only if you are alerted after taking Periway Syrup. Avoid consumption of alcohol with Periway Syrup as it may increase the adverse effects. Please consult a doctor before consuming alcohol with Periway Syrup.

Uses of Periway Syrup

Periway Syrup is used to treat Dry cough. The detailed uses of Periway Syrup are as follows:

  • Cough Relief: Periway Syrup helps relieve dry and productive coughs by soothing the throat and reducing cough frequency and intensity.
  • Anti-allergic Action: Periway Syrup helps relieve allergy symptoms like sneezing, runny nose, and throat irritation due to its antihistamine properties.

Directions for Use

• Periway Syrup can be taken with or without food, as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Shake the bottle well before each use. • Measure the prescribed dose using the measuring cup/dosing syringe/dropper provided with the pack and administer it orally. • Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Periway Syrup is a combination of two drugs: Levodropropizine and Chlorpheniramine maleate. Levodropropizine belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough, thereby decreasing the urge to cough. Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together, Periway Syrup provides relief from cough.

How Periway Syrup Works

Periway Syrup is a combination of two drugs: Levodropropizine (cough suppressant) and Chlorpheniramine maleate (antihistamine). Levodropropizine belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Together, Periway Syrup provides relief from dry cough.

Storage

• Store in a cool and dry place away from sunlight. • Keep Periway Syrup out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Periway Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Periway Syrup may include large pupils, flushing, fever, hallucinations, weakness, shaking, muscle twitching, loss of consciousness, and seizures. In children, excitement may occur first, followed by loss of coordination, drowsiness, loss of consciousness, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Periway Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Periway Syrup. Periway Syrup is not recommended for children below 2 years of age. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Periway Syrup.

Drug-Drug Interactions

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ChlorpheniraminePotassium citrate
Critical

Drug-Drug Interactions

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ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Periway Syrup:
Taking Periway Syrup and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Periway Syrup with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periway Syrup:
Taking Periway Syrup and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Periway Syrup with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periway Syrup:
Taking Periway Syrup with Topiramate can increase the risk of side effects including high body temperatures and decreased sweating, sun stroke.

How to manage the interaction:
Although taking Periway Syrup and Topiramate together can result in an interaction, it can be taken if your doctor has advised it. During warm weather and when exercising, you should drink lots of fluids. If your sweating is less than usual or you have a fever, if you feel lightheaded or dizzy, consult a doctor. Avoid activities requiring mental attention such as driving or operating dangerous machinery. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Periway Syrup:
Taking Periway Syrup with Idelalisib together can increase the levels of Periway Syrup which may lead to side effects.

How to manage the interaction:
Although taking Periway Syrup and Idelalisib together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Periway Syrup:
Co-administration of Periway Syrup with Ketamine can increase the risk of side effects.

How to manage the interaction:
Taking Periway Syrup and Ketamine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, and breathing difficulty. Avoid activities requiring mental focus such as driving, operating dangerous machinery. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periway Syrup:
Co-administration of Periway Syrup with mexiletine may cause the side effects of mexiletine.

How to manage the interaction:
Although taking Periway Syrup and mexiletine together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
ChlorpheniramineSodium oxybate
Severe
How does the drug interact with Periway Syrup:
Taking Periway Syrup with Sodium oxybate can enhance the risk of side effects.

How to manage the interaction:
Co-administration of Periway Syrup with Sodium oxybate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience- drowsiness, dizziness, lightheadedness, confusion, breathing difficulty, and impairment in thinking, judgment, and motor coordination, consult the doctor. You should take care when getting up from a sitting or lying posture, and avoid operating machinery, driving, or participating in any potentially dangerous activity requiring mental attention and motor coordination for at least six hours after taking sodium oxybate.
ChlorpheniramineEluxadoline
Severe
How does the drug interact with Periway Syrup:
Taking Periway Syrup with Eluxadoline can increase the levels of both the medications, which may the risk of constipation and other stomach related problems.

How to manage the interaction:
There may be a possibility of interaction between Periway Syrup and Eluxadoline, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ChlorpheniramineIsocarboxazid
Severe
How does the drug interact with Periway Syrup:
Co-administration of Periway Syrup with Isocarboxazid can increase the risk of side effects.

How to manage the interaction:
Taking Periway Syrup with Isocarboxazid can result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of these symptoms - dizziness, drowsiness, confusion, disorientation, memory problems, blurred vision, dry mouth, constipation, heat intolerance, flushing, decreased sweating, difficulty urinating, rapid heartbeat, - make sure to consult the doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Periway Syrup:
Taking Periway Syrup and Ethanol together may increases the risk of side effects.

How to manage the interaction:
Although taking Periway Syrup and Ethanol together can result in an interaction, it can be taken if your doctor has advised it. Avoid physical activities such as driving or operating machinery. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.

  • Drink plenty of fluids to avoid a dry throat while you have a cough. It also helps loosen mucus.

  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS
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Alcohol

Unsafe

Avoid consumption of alcohol with Periway Syrup as it may increase the adverse effects. Please consult a doctor before consuming alcohol with Periway Syrup.

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Pregnancy

Caution

The safety of Periway Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Periway Syrup may be excreted in breast milk and cause harm to the baby. Therefore, Periway Syrup should not be used in breastfeeding mothers without a doctor’s advice.

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Driving

Caution

Periway Syrup may cause dizziness, drowsiness, blurred vision or impaired thinking in some people. Therefore, drive only if you are alert after taking Periway Syrup.

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Liver

Caution

Take Periway Syrup with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Periway Syrup with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Caution

Periway Syrup is not recommended for children below 2 years of age. Please consult a doctor before using Periway Syrup in children.

Have a query?

FAQs

Periway Syrup belongs to a class of medication called cough and cold preparations used to treat dry cough.

Periway Syrup contains Levodropropizine and Chlorpheniramine maleate. Levodropropizine works by decreasing the activity of the cough centre in the brain. Thus, decreases the urge to cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

No, you are not recommended to consume alcohol with Periway Syrup as it may increase drowsiness. However, please consult a doctor before consuming alcohol with Periway Syrup.

Yes, Periway Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Periway Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene. However, if the condition persists or worsens, please consult a doctor.

Periway Syrup may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Periway Syrup contains Chlorpheniramine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

You are recommended to avoid taking Periway Syrup if you have asthma, glaucoma, enlarged prostate, urinary problems, blockage in the stomach or intestines. However, if you have any of these conditions, please inform your doctor before taking Periway Syrup.

Periway Syrup is not recommended for children below 2 years of age. However, Periway Syrup should be used with caution in children above 2 years if prescribed by a doctor as misuse of Periway Syrup in children may lead to serious adverse effects.

You are recommended to take Periway Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Periway Syrup, please consult your doctor.

No, you are not recommended to stop taking Periway Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Periway Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Periway Syrup, please consult your doctor.

Yes, Periway Syrup may cause sleepiness or drowsiness as a common side effect. If you experience sleepiness or drowsiness, avoid driving and operating heavy machinery unless you feel fully alert.

Serious side effects with Periway Syrup are rare and uncommon. However, contact the doctor immediately if you notice any allergic reactions, skin rash or peeling, mouth ulcers, breathing difficulties, frequent fevers or infections, vision disturbances, or fast or irregular heartbeat.

No, taking more than the recommended dose of Periway Syrup will not be effective, rather it may cause unpleasant side effects. Therefore, always take Periway Syrup in the prescribed doses to prevent adverse effects and to get full benefits.

No, you should not breastfeed while taking Periway Syrup without consulting the doctor, as it may pass into breastmilk and cause harm to the baby. Therefore, consult the doctor before taking Periway Syrup if you are a breastfeeding woman.

You should not take Periway Syrup if you are allergic to any of its ingredients and avoid taking over-the-counter medications without a doctor’s advice.

Periway Syrup should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

The side effects of Periway Syrup include constipation, dry mouth, drowsiness, vomiting, blurred vision, dizziness or tiredness. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India
Other Info - PE12486

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