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compositionComposition:PENTAZOCINE-30MG
prescription
Prescription Medicine
info
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Pentavin Injection 1 ml is used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic, for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. It contains Pentazocine, which changes how the nervous system and brain respond to pain. Thereby, it helps provide relief from pain.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PENTAZOCINE-30MG

Manufacturer/Marketer :

Biochem Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pentavin Injection 1 ml

Pentavin Injection 1 ml is a prescription opioid pain medicine given by injection to manage moderate to severe pain when an injectable pain reliever is appropriate, such as after surgery, injury, or certain medical procedures. It changes how your brain and nervous system respond to pain, helping improve comfort while pain is being treated.

Pentavin Injection 1 ml is generally used for short-term pain management rather than long-term treatment of chronic pain. It may be given when needed or at scheduled times, depending on your pain and response to treatment. Because pentazocine can cause physical dependence with repeated use, your doctor will use the dose and duration appropriate for your individual needs.

Some people may experience drowsiness, dizziness, nausea, or vomiting. Pentazocine can also cause changes in mood, confusion, or hallucinations (seeing or hearing things that are not there), and these effects may occur more often with pentazocine than with many other opioid pain medicines. Tell your doctor promptly if you or your caregiver notices unusual changes in your mood, behaviour, or perception. Seek medical attention promptly for slow or shallow breathing, marked drowsiness, or signs of a serious allergic reaction.

Before receiving Pentavin Injection 1 ml, tell your doctor if you have breathing problems, kidney or liver disease, a head injury, or a history of substance misuse or dependence. Also tell your doctor if you regularly take other opioid pain medicines, such as morphine, oxycodone, or fentanyl. Pentazocine acts differently from these opioids and may reduce their pain-relieving effects or trigger withdrawal symptoms if your body has become dependent on them.

Alcohol and medicines that cause drowsiness can increase sedation and breathing-related side effects when used with Pentavin Injection 1 ml. Tell your doctor about all medicines you take before treatment. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, your doctor will consider your individual circumstances and decide whether Pentavin Injection 1 ml is appropriate for you.

Uses of Pentavin Injection 1 ml

Your doctor may prescribe Pentavin Injection 1 ml to help manage the following conditions:

  • Moderate to severe pain: It acts quickly to ease intense pain resulting from surgeries, injuries, or severe medical conditions.
  • Anaesthesia support: It is used before surgery to help you relax and make the transition into anaesthesia smoother.

Key Benefits

Pentavin Injection 1 ml can help make periods of significant pain more manageable, improving your comfort while you receive treatment or recover.

  • Greater comfort: Effective pain control can make it easier to rest, sleep, change position, and move with less discomfort.
  • Supports recovery: When pain is adequately controlled, you may be better able to take part in important recovery activities, such as walking, deep breathing, or physiotherapy after surgery or injury.
Side effects of Pentavin Injection 1 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • If taking a prescription drug causes euphoria as a side effect. Discuss with your physician. Medication changes or dosage adjustments can be required.
  • Activities that benefit stabilize mood include breathing techniques, meditation, and moderate yoga.
  • Normal sleep habits, as rest is necessary for emotional balance.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Pentavin Injection 1 ml will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.

How Pentavin Injection 1 ml Works

Pentavin Injection 1 ml contains pentazocine. It works by targeting specific areas in your brain and nervous system called opioid receptors. When you feel pain, your nerves send distress signals to your brain. This medicine attaches to these receptors to block those signals, effectively turning down the volume on the pain you feel. Additionally, it has a unique dual action that helps relieve pain while reducing some of the risks of deep sedation compared to other strong pain medicines.
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Alcohol

Unsafe

Avoid the consumption of alcohol, as it may cause profound sedation.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Pentavin Injection 1 ml. Prolonged use of Pentavin Injection 1 ml in pregnancy may cause neonatal opioid withdrawal syndrome.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Pentavin Injection 1 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks. Infants exposed to Pentavin Injection 1 ml through breast milk should be monitored for excessive sedation and respiratory depression. Withdrawal symptoms can develop in breastfed babies when maternal administration of an opioid painkiller is stopped or when nursing is terminated.

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Driving

Unsafe

Pentavin Injection 1 ml may alter your physical and mental ability. Therefore, avoid driving or operating machinery.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Pentavin Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Pentavin Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Pentavin Injection 1 ml is not recommended for use in children under one year. The doctor will decide the dose of this medicine based on the age, body weight and clinical condition of your child.

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Heart

Caution

Pentavin Injection 1 ml should be used with caution in patients with heart problems. It can affect breathing, blood pressure, and heart rhythm, especially in those with weakened physical condition or underlying cardiovascular issues. Always consult your doctor before receiving this medication to ensure it's safe for your specific heart condition.

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Geriatrics

Caution

Geriatric patients may receive Pentavin Injection 1 ml, but only under strict medical supervision. Older adults are more sensitive to its side effects such as drowsiness, confusion, respiratory depression, and cardiovascular changes so dose adjustments and close monitoring are essential.

What if I have taken an overdose of Pentavin Injection 1 ml

If you suspect an overdose, seek emergency medical help immediately. Signs of an overdose can include extreme sleepiness, very slow or shallow breathing, cold and clammy skin, or small, pinpoint pupils.

Diet & Lifestyle Advise

  • Stay hydrated: Drink enough fluids throughout the day unless your doctor has advised you to limit your fluid intake. This can also help prevent constipation.
  • Include fibre in your diet: Eat fibre-rich foods such as fruits, vegetables, whole grains, and pulses to help maintain regular bowel movements. Ask your doctor for advice if constipation becomes troublesome.
  • Stand up slowly: Pentavin Injection 1 ml may cause dizziness or light-headedness, particularly when you get up from sitting or lying down. Rise slowly and steady yourself if needed to reduce the risk of falls.
  • Avoid alcohol: Do not drink alcohol while receiving Pentavin Injection 1 ml, as it may increase drowsiness, dizziness, and the risk of slowed or shallow breathing.
  • Allow time for recovery: Get adequate rest and gradually return to your usual activities as advised by your healthcare team, particularly after surgery, injury, or a medical procedure.
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How Soon It Starts Working

The time required for Pentavin Injection 1 ml to start to work: Pentavin Injection 1 ml ideally starts working within 2 to 3 minutes of intravenous, 15 to 20 minutes of intramuscular and subcutaneous administration. The time for which the effects of Pentavin Injection 1 ml last: The effect of Pentavin Injection 1 ml lasts for 3 hours.

What if you forget to take Pentavin Injection 1 ml

If you are receiving this injection on a regular schedule and you miss a dose, contact your doctor or nurse for instructions. If you use it only as needed for pain, you do not need to worry about a missed dose.

Storage

• Store Pentavin Injection 1 ml injections at room temperature, ideally between 20°C and 25°C (68°F to 77°F). 

Drug Warnings

  • Use only as prescribed: Receive Pentavin Injection 1 ml at the dose and frequency prescribed for you. Do not use more than recommended, as pentazocine can cause dependence and other opioid-related side effects.
  • Check the injection: If you have been instructed to handle the medicine, check the solution before use and follow the product instructions. Do not use it if you notice unexpected discolouration or particles.
  • Driving and machinery: Pentavin Injection 1 ml may cause drowsiness, dizziness, or reduced alertness. Avoid driving, cycling, operating machinery, or other activities requiring full attention until you know how the medicine affects you.
  • Do not share your medicine: Pentavin Injection 1 ml has been prescribed specifically for you. Do not give it to anyone else, even if they have similar pain.
  • Do not stop suddenly: If you have been receiving Pentavin Injection 1 ml regularly, do not stop it suddenly without speaking to your doctor. Your dose may need to be reduced gradually to help prevent withdrawal symptoms.
  • Tell your doctor about opioid use: Before receiving Pentavin Injection 1 ml, tell your doctor if you regularly use other opioid pain medicines. Pentazocine may reduce their effects or cause withdrawal symptoms in people who are physically dependent on opioids.
  • Report breathing changes: Seek medical advice promptly if you develop unusual sleepiness or slow or shallow breathing, particularly after starting treatment or following a dose increase.

Drug-Drug Interactions

verifiedApollotooltip
  • Sleeping pills (e.g. zolpidem or temazepam): Using these medicines with Pentavin Injection 1 ml may increase drowsiness, sedation, and the risk of slowed or shallow breathing.
  • Anti-anxiety medicines (e.g. diazepam or lorazepam): Taking these medicines with Pentavin Injection 1 ml may increase sedation, dizziness, and breathing problems. Your doctor may adjust your treatment or monitor you more closely.
  • Muscle relaxants (e.g. baclofen or tizanidine): Using these medicines with Pentavin Injection 1 ml may increase drowsiness, dizziness, and reduced alertness.
  • Other opioid pain medicines (e.g. morphine, oxycodone, or fentanyl): Pentavin Injection 1 ml may reduce the pain-relieving effects of some opioids and may cause withdrawal symptoms in people who are physically dependent on them.
  • MAO inhibitors (e.g. phenelzine, tranylcypromine, or selegiline): These medicines may interact with Pentavin Injection 1 ml and increase the risk of changes in alertness, breathing, or blood pressure. Tell your doctor if you take an MAO inhibitor or have taken one recently.
PentazocineNaltrexone
Critical
PentazocineFluoxetine
Severe

Drug-Drug Interactions

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PentazocineNaltrexone
Critical
How does the drug interact with Pentavin Injection 1 ml:
Taking Naltrexone with Pentavin Injection 1 ml can reduce the effects of Pentavin Injection 1 ml and make the medication less effective.

How to manage the interaction:
Taking Pentavin Injection 1 ml with Naltrexone is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience any symptoms like nausea, vomiting, diarrhoea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
PentazocineFluoxetine
Severe
How does the drug interact with Pentavin Injection 1 ml:
Co-administration of Pentavin Injection 1 ml with Fluoxetine can increase the risk of serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although there is a possible interaction between Pentavin Injection 1 ml and Fluoxetine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PentazocineSodium oxybate
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Sodium oxybate can increase the risk of serious side effects.

How to manage the interaction:
Taking Pentavin Injection 1 ml with Sodium oxybate together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without consulting your doctor.
PentazocineVilazodone
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Vilazodone may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vilazodone with Pentavin Injection 1 ml together can possibly result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
PentazocineIloperidone
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Iloperidone can increase the risk of serious side effects.

How to manage the interaction:
Taking Pentavin Injection 1 ml with Iloperidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PentazocineFurazolidone
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Furazolidone can increase the risk of serious side effects.

How to manage the interaction:
Co-administration of Pentavin Injection 1 ml with Furazolidone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PentazocineSibutramine
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Sibutramine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Pentavin Injection 1 ml and Sibutramine together can evidently cause an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PentazocinePrimidone
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Primidone with Pentavin Injection 1 ml can increase the risk of serious side effects.

How to manage the interaction:
Taking Pentavin Injection 1 ml with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PentazocineRizatriptan
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Pentavin Injection 1 ml with Rizatriptan can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Pentavin Injection 1 ml and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
PentazocineCyclobenzaprine
Severe
How does the drug interact with Pentavin Injection 1 ml:
Taking Cyclobenzaprine with Pentavin Injection 1 ml can increase the risk of serious side effects.

How to manage the interaction:
There may be a possibility of interaction between Pentavin Injection 1 ml and Cyclobenzaprine, but it can be taken if your doctor has advised it. However, if you experience dizziness, shortness of breath, or palpitations, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Pentavin Injection 1 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[NARCOTIC (OPIOID) ANALGESIC]

FAQs

Pentavin Injection 1 ml is used to treat Pain.
Pentavin Injection 1 ml works by changing the way the nervous system and brain respond to pain.
Pentavin Injection 1 ml may cause respiratory depression. Monitoring for respiratory depression during the initiation of treatment or following a dose increase is advised.
It is contraindicated for use in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Consult your doctor if you have any concerns.
While on therapy with Pentavin Injection 1 ml, be cautious if you have experience drowsiness and dizziness, or if you have breathing problems, and avoid driving or operating heavy machinery. Inform your doctor, if you have respiratory depression, asthma, gastrointestinal obstruction, liver or kidney issues, low blood pressure, seizures, heart problems, or a history of biliary surgery. Consult your doctor if pregnant or breastfeeding. Be aware of the potential for dependence or withdrawal symptoms with prolonged use of Pentavin Injection 1 ml with opioids, benzodiazepines, alcohol, or other CNS depressants, as they can cause severe sedation and breathing problems. Therefore, monitoring is recommended due to the risk of respiratory depression.
Pentavin Injection 1 ml causes side effects such as nausea, vomiting, dizziness or lightheadness, and euphoria (a feeling of intense happiness or excitement). However, please contact a doctor if these side effects persist for longer durations.
No, this medicine can make you feel very sleepy or dizzy. It is not safe to drive or operate machinery until you know how it affects you. Talk to your doctor for guidance.
Yes, like many strong pain relievers, Pentavin Injection 1 ml carries a risk of dependence if used for a long time. Always use it exactly as prescribed by your healthcare provider. Talk to your doctor if you have concerns.
Nausea is a common side effect of this medicine. Lying down quietly for a short time can help ease this feeling. Talk to your doctor if the nausea is severe or does not go away.
This medicine should only be used during pregnancy or breastfeeding if your doctor decides it is absolutely necessary, as it can affect the baby. Talk to your doctor about the risks and benefits.
In most cases, this medicine is injected by a healthcare professional in a clinic. If you are cleared to inject it at home, you must receive proper training first. Talk to your doctor or pharmacist to learn the safe technique.
Signs of an allergic reaction include skin rash, hives, itching, or swelling of your face, lips, tongue, or throat, as well as trouble breathing. If you experience these, seek emergency medical help immediately.
If you have been using this medicine regularly, stopping it suddenly can lead to withdrawal symptoms like sweating, shaking, or anxiety. Talk to your doctor about gradually decreasing your dose safely.

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Country of origin

India

Manufacturer/Marketer address

BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.
Other Info - PEN0516

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