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compositionComposition:FLUPENTIXOL-40MG
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Prescription Medicine
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Pencalm-40 Injection 2 ml belongs to a class of medications called antipsychotics. It contains flupentixol which is used to treat schizophrenia (a mental illness) and other psychotic disorders. This medicine works by inhibiting the dopamine (chemical messenger) receptors in the brain and thereby helps improve feelings, disturbing thoughts, and behaviour.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUPENTIXOL-40MG

Manufacturer/Marketer :

Vrddhi Life Sciences

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pencalm-40 Injection 2 ml

Pencalm-40 Injection 2 ml is a long-acting injection used to treat schizophrenia and other long-term mental health conditions known as chronic psychoses. Its primary medical purpose is to help control symptoms like unusual thoughts, hallucinations, and confusion, while preventing these symptoms from returning. By providing a steady release of medication, it supports long-term mental stability and helps you manage your daily life more easily.

Because this medicine is a long-acting depot injection, it is typically given once every 2 to 4 weeks by a healthcare professional. Staying consistent with your injection schedule is vital to keeping your symptoms under control and preventing a relapse. Along with your regular injections, maintaining a stable daily routine, getting enough sleep, and staying well-hydrated can help improve your overall treatment results.

While taking Pencalm-40 Injection 2 ml, you may experience some common side effects such as drowsiness, dry mouth, or mild shakiness. However, you must contact your doctor immediately if you develop serious side effects, such as severe muscle stiffness, a sudden high fever, rapid breathing, or unusual, uncontrollable movements of your tongue, face, or limbs.

Before you begin treatment, tell your doctor if you have any pre-existing health conditions, especially liver damage, heart problems, or Parkinson's disease. Do not take this medicine if you have severe central nervous system depression, are in a coma, or have circulatory collapse.

This medicine can interact with alcohol, causing extreme sleepiness and slowed reactions, so it is best to avoid alcohol entirely. Be sure to inform your doctor about all other medicines you take, as some can cause unsafe drops in blood pressure or increase drowsiness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting treatment to discuss the potential risks and benefits.

Uses of Pencalm-40 Injection 2 ml

Your doctor may prescribe Pencalm-40 Injection 2 ml to help manage the following conditions:

  • Schizophrenia: Pencalm-40 Injection 2 ml helps reduce and manage long-term symptoms such as hearing voices, seeing things that are not there, and experiencing suspicious or unusual thoughts.
  • Chronic psychosis: Pencalm-40 Injection 2 ml helps stabilise mood, clear thinking, and prevent the return of severe mental disturbances in long-term psychotic conditions.

Key Benefits

When used as directed as part of your treatment plan, Pencalm-40 Injection 2 ml may provide the following benefits:

  • Symptom control: Helps reduce symptoms such as hallucinations, unusual thoughts, confusion, and suspiciousness.
  • Reduced risk of relapse: Regular treatment may help prevent symptoms from returning or becoming worse.
  • Improved daily functioning: As symptoms improve, it may become easier to think clearly and take part in everyday activities.
  • Long-lasting treatment: Provides ongoing treatment between scheduled injections, reducing the need to remember daily tablets.
  • Long-term symptom management: Helps maintain symptom control over time when used regularly as prescribed.

Directions for Use

  • Pencalm-40 Injection 2 ml is administered by a qualified healthcare professional, typically in a hospital or clinic setting.
  • Your doctor will determine the appropriate dosage and frequency based on your condition and other factors.
  • Follow your healthcare provider's instructions about the medication and any steps to track your progress or precautions during treatment.

How Pencalm-40 Injection 2 ml Works

Pencalm-40 Injection 2 ml contains flupentixol. It belongs to a group of medicines known as antipsychotics. It works by balancing certain natural chemical messengers in your brain, particularly dopamine. Overactive dopamine pathways are linked to the hallucinations, confusion, and disorganised thinking seen in psychosis. By gently blocking these dopamine receptors, Pencalm-40 Injection 2 ml calms excessive brain activity, helping to clear your thoughts and reduce distressing emotional and physical symptoms. Because this is a depot injection, the active medicine is suspended in a specialised oil that releases slowly into your muscle tissue over several weeks, ensuring constant, day-to-day brain chemistry balance.
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Alcohol

Unsafe

Avoid consumption of alcohol with Pencalm-40 Injection 2 ml as it may increase drowsiness and other adverse effects.

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Pregnancy

Caution

Pencalm-40 Injection 2 ml is not recommended during pregnancy, especially in the first and third trimesters, unless it is clearly necessary. It may cause adverse effects in the baby, such as muscle stiffness, shaking, sleepiness, weakness, breathing problems and difficulty in the foetus. Therefore, if you are pregnant or planning pregnancy, please inform your doctor before taking Pencalm-40 Injection 2 ml.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor before receiving Pencalm-40 Injection 2 ml.

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Driving

Caution

Pencalm-40 Injection 2 ml may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel dizzy, drowsy, or experience any vision problems after taking Pencalm-40 Injection 2 ml.

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Liver

Caution

Take Pencalm-40 Injection 2 ml with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required. If you have liver problems, your doctor may monitor levels of Flupentixol in your blood.

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Kidney

Caution

If you have kidney problems, inform your doctor before taking Pencalm-40 Injection 2 ml. Your doctor may adjust the dose of this medicine as necessary.

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Children

Unsafe

Pencalm-40 Injection 2 ml is not recommended for children and adolescents as safety and effectiveness were not established.

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Heart

Caution

Pencalm-40 Injection 2 ml may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Pencalm-40 Injection 2 ml.

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Geriatrics

Caution

Pencalm-40 Injection 2 ml should be used with caution in elderly patients due to an increased risk of side effects. It is important to consult a healthcare professional before use.

What if I have taken an overdose of Pencalm-40 Injection 2 ml

Because this medicine is given by a trained healthcare professional, an overdose is highly unlikely. However, if you suspect you have received too much, or if you experience severe drowsiness, extremely fast or irregular heartbeat, or severe trembling, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water, especially during hot weather or exercise, as this medicine may make it harder for your body to cool itself.
  • Change positions slowly: Stand up gradually from sitting or lying down to help reduce dizziness or light-headedness.
  • Limit caffeine: Too much coffee, tea, or caffeinated soft drinks may worsen restlessness or make it harder to relax.
  • Eat a balanced diet: Include plenty of vegetables, fruits, whole grains, and lean protein to support your overall health.
  • Monitor your weight: Check your weight regularly, as this medicine may increase your appetite or cause weight gain.
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How Soon It Starts Working

The time required for Pencalm-40 Injection 2 ml to start to work: Pencalm-40 Injection 2 ml ideally shows its action within 1 to 3 days after administration. The time for which the effects of Pencalm-40 Injection 2 ml last: The effect of Pencalm-40 Injection 2 ml lasts for 2 to 4 weeks.

What if you forget to take Pencalm-40 Injection 2 ml

If you miss an appointment for your injection, contact your healthcare clinic or doctor immediately to reschedule. It is important to receive your medicine as close to your scheduled date as possible to prevent your symptoms from returning. Do not receive a double dose to make up for a missed one.

Storage

• Store the medicine below 25°C (77°F). Do not freeze it.

Drug Warnings

  • Driving and machinery: Avoid driving, cycling, or operating machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness.
  • Medical appointments: Attend all scheduled injection appointments to help keep your symptoms under control.
  • Tell healthcare professionals: Inform your doctor, dentist, or surgeon that you are receiving Pencalm-40 Injection 2 ml before any medical procedure or surgery.
  • Keep track of treatment: Use a calendar or phone reminder to help you remember your injection appointments.
  • Avoid alcohol: Drinking alcohol may increase drowsiness and reduce your alertness while receiving this medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Sleeping pills, anxiety medicines, and strong pain relievers: May dangerously increase sleepiness and slow down your breathing when used together.
  • Parkinson’s disease medicines: Pencalm-40 Injection 2 ml may reduce the effectiveness of these medicines, worsening Parkinson's symptoms.
  • Blood pressure medicines: May cause your blood pressure to drop too low when first starting treatment, leading to dizziness or fainting.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid alcohol entirely, as it can significantly increase drowsiness, dizziness, and other central nervous system side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Pencalm-40 Injection 2 ml is an antipsychotic medicine used in the treatment of schizophrenia (a mental illness) and other psychotic disorders.
Pencalm-40 Injection 2 ml contains Flupentixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Pencalm-40 Injection 2 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour.
Pencalm-40 Injection 2 ml should be used with caution in asthma patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have asthma or other breathing problems before taking Pencalm-40 Injection 2 ml.
Pencalm-40 Injection 2 ml may not be recommended to take before surgery. However, inform your surgeon, anaesthetist or dentist before any surgery that you are on treatment with Pencalm-40 Injection 2 ml as it may increase the effects of muscle relaxing drugs, general anaesthesia and drugs used to prevent blood clots.
Pencalm-40 Injection 2 ml may affect fertility as it reduces sexual activity. However, it is a temporary effect. Please consult a doctor if you are planning for pregnancy before taking Pencalm-40 Injection 2 ml.
Pencalm-40 Injection 2 ml should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Pencalm-40 Injection 2 ml.
You are not recommended to take Pencalm-40 Injection 2 ml with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Pencalm-40 Injection 2 ml with any other medicines.
No, you should not stop your injections without consulting your healthcare provider first. Stopping the medicine suddenly can cause your symptoms to return quickly. Talk to your doctor about how to safely manage your treatment.
Most patients receive their injection once every 2 to 4 weeks. Your doctor will determine the best interval for you based on your response to the treatment. Talk to your doctor to understand your specific schedule.
Contact your clinic or doctor right away to reschedule. Missing an injection can lead to a return of your symptoms, so it is important to get your next dose as soon as possible. Talk to your doctor or pharmacist if you are concerned.
No, you should avoid alcohol while on this medication. Alcohol can increase the sedative effects of the injection, causing severe drowsiness and sluggishness. Talk to your doctor if you find it difficult to avoid alcohol.
Yes, some people may experience weight gain or an increased appetite while receiving this injection. Managing your diet and staying physically active can help control this. Talk to your doctor or a dietitian for personalised advice.
This medicine can cause drowsiness, dizziness, and slow reaction times, especially during the first few days after an injection. Avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if you have safety concerns.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the risks. It may cause temporary withdrawal symptoms in newborns. Talk to your doctor to discuss your options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

2828, B-Type, 67th Street, Mathur, MMDA, Chennai - 600068, Tamil Nadu, India
Other Info - PEN0537

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