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  3. Palmocet 0.25 Injection 5 ml

Palmocet 0.25 Injection 5 ml, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Palmocet 0.25 Injection 5 ml is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone) located in the brain. Thus, it prevents nausea and vomiting. Common side effects of Palmocet 0.25 Injection 5 ml are diarrhoea, constipation, dizziness or headache.
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Composition :

PALONOSETRON-0.25MG

Manufacturer/Marketer :

Miracalus Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Palmocet 0.25 Injection 5 ml

Palmocet 0.25 Injection 5 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Palmocet 0.25 Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Palmocet 0.25 Injection 5 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Palmocet 0.25 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Palmocet 0.25 Injection 5 ml or any other medicines, please tell your doctor. Palmocet 0.25 Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palmocet 0.25 Injection 5 ml. Drive only if you are alert as Palmocet 0.25 Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of Palmocet 0.25 Injection 5 ml

Palmocet 0.25 Injection 5 ml is used in the treatment of Nausea and vomiting. The detailed uses of Palmocet 0.25 Injection 5 ml are as follows:<br/>• Chemotherapy-Induced Nausea and Vomiting (CINV): Palmocet 0.25 Injection 5 ml prevents acute and delayed CINV, providing long-lasting relief and improving patient quality of life during chemotherapy.<br/>• Postoperative Nausea and Vomiting (PONV): Palmocet 0.25 Injection 5 ml prevents PONV, reducing patient discomfort and promoting smoother recovery after surgery.<br/>

Directions for Use

• Palmocet 0.25 Injection 5 ml is administered only in clinical settings by healthcare professionals, usually through intravenous or intramuscular injections.• The dosage and timing are decided by the doctor, depending on the cause and severity of symptoms.• Do not self-administer this medication.• Patients are monitored during and after administration to ensure safety and effective control of symptoms.

Medicinal Benefits

Palmocet 0.25 Injection 5 ml contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

How Palmocet 0.25 Injection 5 ml Works

Palmocet 0.25 Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Palmocet 0.25 Injection 5 ml out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Palmocet 0.25 Injection 5 ml
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Palmocet 0.25 Injection 5 ml

As Palmocet 0.25 Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Palmocet 0.25 Injection 5 ml may cause bluish colour of the fingernails, lips, skin, palms, or nail beds, collapse, gasping to breathe, paleness of the skin, and seizures.

Drug Warnings

If you are allergic to Palmocet 0.25 Injection 5 ml or any other medicines, please tell your doctor. Palmocet 0.25 Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palmocet 0.25 Injection 5 ml. Drive only if you are alert as Palmocet 0.25 Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interactions

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PalonosetronZiprasidone
Critical
PalonosetronDextromethorphan
Severe

Drug-Drug Interactions

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PalonosetronZiprasidone
Critical
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Combining Palmocet 0.25 Injection 5 ml with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Taking Ziprasidone with Palmocet 0.25 Injection 5 ml is not recommended, please consult your doctor before taking it.
PalonosetronDextromethorphan
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Co-administration of Dextromethorphan and Palmocet 0.25 Injection 5 ml may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Dextromethorphan and Palmocet 0.25 Injection 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
PalonosetronVilazodone
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
When Vilazodone is taken with Palmocet 0.25 Injection 5 ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Palmocet 0.25 Injection 5 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
PalonosetronParoxetine
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Using Palmocet 0.25 Injection 5 ml together with paroxetine can increase the risk of condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Paroxetine with Palmocet 0.25 Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PalonosetronBuspirone
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Using Buspirone together with Fenfluramine can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Co- administration of buspirone along with Palmocet 0.25 Injection 5 ml can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
PalonosetronChloroquine
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Using chloroquine together with Palmocet 0.25 Injection 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Palmocet 0.25 Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PalonosetronFentanyl
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Taking fentanyl with Palmocet 0.25 Injection 5 ml may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Fentanyl with Palmocet 0.25 Injection 5 ml can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
PalonosetronPentazocine
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Taking Palmocet 0.25 Injection 5 ml with Pentazocine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Palmocet 0.25 Injection 5 ml, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PalonosetronDoxepin
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
The combined use of Palmocet 0.25 Injection 5 ml and doxepin can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin builds up in your body) and increase the risk of irregular heart rhythms.

How to manage the interaction:
Co-administration of Palmocet 0.25 Injection 5 ml and Doxepin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhoea, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
PalonosetronAmiodarone
Severe
How does the drug interact with Palmocet 0.25 Injection 5 ml:
Coadministration of Amiodarone with Palmocet 0.25 Injection 5 ml can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Palmocet 0.25 Injection 5 ml together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Palmocet 0.25 Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Palmocet 0.25 Injection 5 ml is unknown. Please consult a doctor before consuming alcohol with Palmocet 0.25 Injection 5 ml.

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Pregnancy

Consult your doctor

Palmocet 0.25 Injection 5 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Please inform your doctor before taking Palmocet 0.25 Injection 5 ml if you are breastfeeding. Palmocet 0.25 Injection 5 ml is given to breastfeeding women only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Palmocet 0.25 Injection 5 ml may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Palmocet 0.25 Injection 5 ml.

bannner image

Liver

Safe if prescribed

Palmocet 0.25 Injection 5 ml may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

bannner image

Kidney

Safe if prescribed

Palmocet 0.25 Injection 5 ml may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

bannner image

Children

Caution

Palmocet 0.25 Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight.

Have a query?

FAQs

Palmocet 0.25 Injection 5 ml is used to treat nausea and vomiting.

Palmocet 0.25 Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with Palmocet 0.25 Injection 5 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Palmocet 0.25 Injection 5 ml.

Palmocet 0.25 Injection 5 ml may cause constipation as a side effect. It is not necessary for everyone taking Palmocet 0.25 Injection 5 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

Palmocet 0.25 Injection 5 ml should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have Palmocet 0.25 Injection 5 ml so that the dose may be adjusted appropriately.

Country of origin

India

Manufacturer/Marketer address

213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.
Other Info - PAL0169

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:02 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.513.pdf

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