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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Palbace 125 mg Tablet is an anti-cancer medicine used in the treatment of certain types of breast cancer. This medicine contains palbociclid which works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Common side effects include weakness, loss of appetite, infections and dry skin.
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Composition :

PALBOCICLIB-125MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Palbace 125 mg Tablet

Palbace 125 mg Tablet belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Palbace 125 mg Tablet contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Palbace 125 mg Tablet is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Palbace 125 mg Tablet as prescribed. In some cases, Palbace 125 mg Tablet may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 125 mg Tablet if you are pregnant or breastfeeding. Palbace 125 mg Tablet may cause tiredness, so drive only if you are alert. Palbace 125 mg Tablet is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Palbace 125 mg Tablet

Palbace 125 mg Tablet is used in the treatment of Breast Cancer. The detailed use of Palbace 125 mg Tablet is as follows:

  • Advanced or metastatic breast cancer: Palbace 125 mg Tablet is used in the treatment of Advanced or metastatic breast cancer that is hormone receptor (HR)-positive and HER2-negative.
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    Directions for Use

    • Palbace 125 mg Tablet can be taken with or without food. However, avoid taking it with grapefruit or grapefruit juice.
    • It is recommended to take Palbace 125 mg Tablet once daily or as prescribed by your doctor.
    • Swallow Palbace 125 mg Tablet as a whole with a glass of water.
    • Do not break, chew, or crush it.

    Medicinal Benefits

    Palbace 125 mg Tablet is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Palbace 125 mg Tablet works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Palbace 125 mg Tablet nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Palbace 125 mg Tablet helps treat breast cancer.

    How Palbace 125 mg Tablet Works

    Palbace 125 mg Tablet contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Palbace 125 mg Tablet is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer.

    Storage

    • Store in a cool and dry place away from sunlight.• Keep Palbace 125 mg Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

    What if I have taken an overdose of Palbace 125 mg Tablet

    Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, and neutropenia (low neutrophil levels). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

    Drug Warnings

    Do not take St. John's wort or grapefruit/grapefruit juice with Palbace 125 mg Tablet . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 125 mg Tablet if you are pregnant or breastfeeding. Palbace 125 mg Tablet may cause tiredness, so drive only if you are alert. Palbace 125 mg Tablet is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

    Diet & Lifestyle Advise

    • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
    • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
    • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
    • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
    • Avoid smoking and alcohol consumption.

    Habit Forming

    No

    Therapeutic Class

    CHEMOTHERAPY

    All Substitutes & Brand Comparisons

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    Alcohol

    Caution

    It is not recommended to use alcohol with Palbace 125 mg Tablet . Please consult your doctor if you have any concerns.

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    Pregnancy

    Unsafe

    Palbace 125 mg Tablet is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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    Breast Feeding

    Unsafe

    Palbace 125 mg Tablet is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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    Driving

    Caution

    Palbace 125 mg Tablet may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Palbace 125 mg Tablet .

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    Liver

    Caution

    Exercise caution before using Palbace 125 mg Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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    Kidney

    Caution

    Exercise caution before using Palbace 125 mg Tablet in case of established kidney disease. Please consult your doctor to address any concerns.

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    Children

    Unsafe

    Palbace 125 mg Tablet is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

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    Heart

    Palbace 125 mg Tablet should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Palbace 125 mg Tablet .

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    Geriatrics

    Consult your doctor

    Palbace 125 mg Tablet should be given to elderly patients only if prescribed by a doctor. Seek medical advice if you have any concerns.

    FAQs

    Palbace 125 mg Tablet belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.

    Palbace 125 mg Tablet works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.

    Do not stop taking Palbace 125 mg Tablet on your own. You are advised to take Palbace 125 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Palbace 125 mg Tablet .

    A fibroadenoma is a benign state. Palbace 125 mg Tablet is indicated only in case of cancers. Please consult your doctor in case of any concerns.

    Palbace 125 mg Tablet can reduce fertility in men. Therefore, consider sperm preservation before starting Palbace 125 mg Tablet if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Palbace 125 mg Tablet .

    Country of origin

    India

    Manufacturer/Marketer address

    The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
    Other Info - PAL0220

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