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  3. Oximox 500mg/125mg Tablet XL

Oximox 500mg/125mg Tablet XL, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Oximox 500mg/125mg Tablet XL is used to treat bacterial infections, including ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joint and bone infections. It works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

AMOXYCILLIN-500MG + CLAVULANIC ACID-125MG

Manufacturer/Marketer :

Lifekyor Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Oximox 500mg/125mg Tablet XL

Oximox 500mg/125mg Tablet XL is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

Oximox 500mg/125mg Tablet XL consists of Amoxycillin and Clavulanic acid. This medicine works by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). As a result, it helps treat infection and reduce the further spread of infection. Oximox 500mg/125mg Tablet XL does not work against infections caused by viruses, including colds and flu.

Not everyone who is taking Oximox 500mg/125mg Tablet XL will get these side effects. The common side effects of Oximox 500mg/125mg Tablet XL include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

You can take Oximox 500mg/125mg Tablet XL with food to avoid any stomach upset. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your medicine based on your medical condition. It is always important to complete your treatment course for better results.

Before starting Oximox 500mg/125mg Tablet XL, please inform your doctor if you have any allergy (against any antibiotic) or any other components. Do not take Oximox 500mg/125mg Tablet XL on your own as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Oximox 500mg/125mg Tablet XL is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor if you are pregnant or breadfeeding before taking Oximox 500mg/125mg Tablet XL.

Uses of Oximox 500mg/125mg Tablet XL

Oximox 500mg/125mg Tablet XL is used to treat Bacterial Infections. The detailed uses of Oximox 500mg/125mg Tablet XL are as follows:<br/> • Bacterial Infections: Oximox 500mg/125mg Tablet XL helps treat bacterial illnesses, including pneumonia and bronchitis. The composition of Oximox 500mg/125mg Tablet XL improves efficacy against resistant microorganisms.<br/> • Sinusitis: Oximox 500mg/125mg Tablet XL treats bacterial sinus infections by lowering inflammation and cleaning them.<br/> • Urinary Tract Infections (UTIs): Oximox 500mg/125mg Tablet XL treats urinary tract infections caused by susceptible bacteria and provides broad-spectrum protection.<br/> • Skin and Soft Tissue Infection: Oximox 500mg/125mg Tablet XL is also prescribed for treating skin and soft tissue infections, such as cellulitis and bite wounds, by its antibacterial effects to speed up the healing process.<br/> • Otitis Media: Oximox 500mg/125mg Tablet XL helps to treat middle ear infections.<br/> • Pneumonia: Oximox 500mg/125mg Tablet XL is also involved in treating pneumonia by efficiently fighting against the microorganisms that cause the condition.

Directions for Use

• Oximox 500mg/125mg Tablet XL can be taken with food to avoid stomach upset. • It is usually taken every 8-12 hours or as prescribed by your doctor. • Swallow Oximox 500mg/125mg Tablet XL as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

  • Oximox 500mg/125mg Tablet XL is a broad-spectrum antibiotic that covers a very wide range of bacterial infections.
  • Oximox 500mg/125mg Tablet XL has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy.
  • Oximox 500mg/125mg Tablet XL helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase.
  • Oximox 500mg/125mg Tablet XL is an effective medicine used in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.

How Oximox 500mg/125mg Tablet XL Works

Oximox 500mg/125mg Tablet XL consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. Oximox 500mg/125mg Tablet XL does not work against infections caused by viruses, including colds and flu.

Storage

Keep Oximox 500mg/125mg Tablet XL out of the sight and reach of children.

What if I have taken an overdose of Oximox 500mg/125mg Tablet XL

Take Oximox 500mg/125mg Tablet XL only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms may include nausea, vomiting, diarrhoea, stomach pain, drowsiness, skin rash, hyperactivity, and decreased urination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Oximox 500mg/125mg Tablet XL if you have an allergy to Oximox 500mg/125mg Tablet XL, penicillin or cephalosporin class of antibiotics. Also, if you experience any allergic symptoms, including rash, swelling of the face/lips/throat, difficulty breathing, or chest tightness after taking $ name, immediately contact your doctor. 
  • People with liver diseases or jaundice (yellowing of skin/eyes) should not take Oximox 500mg/125mg Tablet XL, as it can severely affect the liver. Inform your doctor if you have any kidney or heart disease before taking Oximox 500mg/125mg Tablet XL.
  • The dose of Oximox 500mg/125mg Tablet XL can vary depending on your condition and the severity of the infection. 
  • Additionally, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Drug-Drug Interactions

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AmoxicillinCholera, live attenuated
Severe
AmoxicillinDoxycycline
Severe

Drug-Drug Interactions

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AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Oximox 500mg/125mg Tablet XL:
Co-administration of Oximox 500mg/125mg Tablet XL and Cholera, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Oximox 500mg/125mg Tablet XL or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
AmoxicillinDoxycycline
Severe
How does the drug interact with Oximox 500mg/125mg Tablet XL:
Co-administration of Oximox 500mg/125mg Tablet XL with doxycycline may reduce the therapeutic effect of Oximox 500mg/125mg Tablet XL.

How to manage the interaction:
Although there is a possible interaction between Oximox 500mg/125mg Tablet XL and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
AmoxicillinZalcitabine
Severe
How does the drug interact with Oximox 500mg/125mg Tablet XL:
Co-administration of Oximox 500mg/125mg Tablet XL and Zalcitabine can be decreased when combined with Oximox 500mg/125mg Tablet XL.

How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Oximox 500mg/125mg Tablet XL, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxicillinBCG vaccine
Severe
How does the drug interact with Oximox 500mg/125mg Tablet XL:
Co-administration of BCG vaccine with Oximox 500mg/125mg Tablet XL may reduce the effect of BCG vaccine.

How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Oximox 500mg/125mg Tablet XL. Do not discontinue the medication without consulting a doctor.
AmoxicillinMethotrexate
Severe
How does the drug interact with Oximox 500mg/125mg Tablet XL:
Co-administration of methotrexate with Oximox 500mg/125mg Tablet XL can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Oximox 500mg/125mg Tablet XL, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.
  • Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Probiotics should be taken after taking a full course of Oximox 500mg/125mg Tablet XL in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Avoid alcoholic beverages with Oximox 500mg/125mg Tablet XL as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Oximox 500mg/125mg Tablet XL in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- INFECTIVES

Oximox 500mg/125mg Tablet XL Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol during the treatment with Oximox 500mg/125mg Tablet XL as it may worsen the side effects like dizziness.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking Oximox 500mg/125mg Tablet XL. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

This medication passes into breast milk. If you are a nursing mother, consult your doctor before taking Oximox 500mg/125mg Tablet XL. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Oximox 500mg/125mg Tablet XL may cause dizziness in some people, so it may affect your ability to drive. Avoid driving or operating machines until you are alert after taking Oximox 500mg/125mg Tablet XL.

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Liver

Caution

Oximox 500mg/125mg Tablet XL to be taken with caution if you have a history of liver conditions. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Oximox 500mg/125mg Tablet XL to be taken with caution, especially if you have a history of kidney conditions. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult the doctor. Your child's doctor will decide the dosage of this medicine depending on the weight and the severity of the infection.

Have a query?

FAQs

Oximox 500mg/125mg Tablet XL is used to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, and joint and bone infections.

Oximox 500mg/125mg Tablet XL contains Amoxycillin and Clavulanic acid. Amoxycillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxycillin against the bacteria. Together, Oximox 500mg/125mg Tablet XL helps in treating bacterial infections.

Oximox 500mg/125mg Tablet XL is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects, please take Oximox 500mg/125mg Tablet XL with a meal. Also, Oximox 500mg/125mg Tablet XL should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.

Generally, the penicillin group of antibiotics is not advised to be taken with methotrexate, which is used for conditions like psoriasis, rheumatoid arthritis, etc. They may cause unpleasant side effects when taken together. However, Oximox 500mg/125mg Tablet XL is relatively safer to take with methotrexate, but only if prescribed by the doctor. It is best to discuss with your doctor about using the two medicines together, who may weigh the pros and cons and decide what is best for you.

Usually, Oximox 500mg/125mg Tablet XL does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking the medication for a prolonged time. Please consult your doctor immediately if you notice any yellowing of the skin/eyes.

Oximox 500mg/125mg Tablet XL does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Oximox 500mg/125mg Tablet XL for your condition.

Yes, after taking Oximox 500mg/125mg Tablet XL, you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own; consult your doctor if the condition worsens.

Oximox 500mg/125mg Tablet XL is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to Oximox 500mg/125mg Tablet XL, you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding using Oximox 500mg/125mg Tablet XL and your birth control pills.

Oximox 500mg/125mg Tablet XL may show its effect 1.5 hours after taking the medicine. However, clinical improvement may be noticed after 48 hours.

Oximox 500mg/125mg Tablet XL should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.

Oximox 500mg/125mg Tablet XL contains amoxicillin and clavulanic acid used to treat bacterial infections of the ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joints and bones.

Yes, Oximox 500mg/125mg Tablet XL is safe to use if prescribed by the doctor.

Oximox 500mg/125mg Tablet XL should not be used if you are allergic to any of its components or if you had jaundice or liver problems when taking an antibiotic.

Do not exceed the recommended dose of Oximox 500mg/125mg Tablet XL as it might cause stomach upset or convulsions. Take Oximox 500mg/125mg Tablet XL only as advised by the doctor.

Store Oximox 500mg/125mg Tablet XL at room temperature (below 25°C). Keep it out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your pharmacist regarding the disposal of medicines.

To treat your infection effectively, continue taking Oximox 500mg/125mg Tablet XL for the prescribed duration even if your symptoms are relieved.

Oximox 500mg/125mg Tablet XL may cause an allergic reaction like skin rash, vasculitis (inflammation of blood vessels), angioedema (swelling), and difficulty breathing. Consult the doctor if you experience these symptoms.

No, Oximox 500mg/125mg Tablet XL does not cause drowsiness. Sometimes, it might cause dizziness as an uncommon side effect. Drive or operate machinery only if you are alert.

Oximox 500mg/125mg Tablet XL should be swallowed as a whole with water. Take the medicine with a meal.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Oximox 500mg/125mg Tablet XL.

The common side effects of Oximox 500mg/125mg Tablet XL include vomiting, nausea, and diarrhoea. In case of any discomfort, speak with a doctor.

Oximox 500mg/125mg Tablet XL should be taken only if prescribed by the doctor. It should not be taken by people who are allergic to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of this medicine, ever had a severe allergic reaction (skin rash or swelling of the face or throat) to any other antibiotic or liver problems/jaundice (yellowing of the skin) when taking an antibiotic.

Let the doctor know if you are taking gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drugs (methotrexate), and drugs to prevent organ transplant (mycophenolate mofetil).

Seek immediate medical attention if you have overdosed on Oximox 500mg/125mg Tablet XL. Taking too much of Oximox 500mg/125mg Tablet XL may cause upset stomach (nausea, vomiting or diarrhoea) or convulsions.

Country of origin

India
Other Info - OX13454

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 11:18 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.9127.pdf
  2. https://gskpro.com/en-mt/products/augmentin/indication/
  3. https://www.nhs.uk/medicines/co-amoxiclav/
  4. https://www.drugs.com/augmentin.html
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