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  3. Orviclo-400 mg Tablet 10's

Orviclo-400 mg Tablet 10's, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Orviclo-400 mg Tablet 10's is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox. It contains Aciclovir, which prevents the multiplication of viruses in human cells by acting on their DNA, resulting in decreased viral overload. In some cases, you may experience side effects such as headaches, feeling dizzy, nausea or vomiting, diarrhoea, rash, and skin sensitivity to sunlight. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner.
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Composition :

ACICLOVIR-400MG

Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Orviclo-400 mg Tablet 10's

Orviclo-400 mg Tablet 10's is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox. Orviclo-400 mg Tablet 10's does not cure herpes but does not allow the infection to spread and treat its symptoms.

Orviclo-400 mg Tablet 10's contains Aciclovir, which is an antiviral medication. Orviclo-400 mg Tablet 10's prevents the multiplication of viruses in human cells by acting on their DNA, resulting in decreased viral overload.

Orviclo-400 mg Tablet 10's is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition. In some cases, you may experience headaches, feeling dizzy, feeling or being sick (nausea or vomiting), diarrhoea, rash, and skin sensitivity to sunlight. Most of these side effects of Orviclo-400 mg Tablet 10's are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Orviclo-400 mg Tablet 10's only if the doctor prescribes you. Never encourage self-medication or suggest your medicine to someone else. Do not take Orviclo-400 mg Tablet 10's if you are allergic to Orviclo-400 mg Tablet 10's, aciclovir, or any of its ingredients. Check with your doctor if you're pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner. If you have a weak immune system, please inform your doctor before taking Orviclo-400 mg Tablet 10's as a dose adjustment may be required.

Uses of Orviclo-400 mg Tablet 10's

Treatment of Herpes zoster skin infection(shingles) and Chicken Pox.

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Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Orviclo-400 mg Tablet 10's contains Aciclovir, which is an antiviral medication. Orviclo-400 mg Tablet 10's prevents the multiplication of viruses in human cells by acting on its DNA resulting in decreased viral overload.

How Orviclo-400 mg Tablet 10's Works

Orviclo-400 mg Tablet 10's contains Aciclovir, which is an antiviral medication. Orviclo-400 mg Tablet 10's prevents the multiplication of viruses in human cells by acting on their DNA, resulting in decreased viral overload.

Storage

Keep Orviclo-400 mg Tablet 10's out of the sight and reach of children.
Side effects of Orviclo-400 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

What if I have taken an overdose of Orviclo-400 mg Tablet 10's

Do not take more than the prescribed dose of Orviclo-400 mg Tablet 10's as it may cause overdose. The symptoms of overdose include extreme tiredness, seizures (fits), change in the amount of urine, loss of consciousness and agitation. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Orviclo-400 mg Tablet 10's if you are allergic to Orviclo-400 mg Tablet 10's or any of its ingredients. Inform your doctor about all other OTC medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. If you are 65 years of age or have kidney disease or kidney transplant, heart problem or history of heart problem, have HIV/AIDS, are pregnant, or plan to become pregnant, Orviclo-400 mg Tablet 10's should be taken with caution and only if a doctor prescribes you. Orviclo-400 mg Tablet 10's may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Orviclo-400 mg Tablet 10's so please get up gradually. Also, do not drive a car or operate any machinery which requires concentration as Orviclo-400 mg Tablet 10's may cause dizziness. Please do not take Orviclo-400 mg Tablet 10's if you have ever developed a rash due to fever. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner. If you have a weak immune system, please inform your doctor before taking Orviclo-400 mg Tablet 10's as a dose adjustment may be required. Drink plenty of fluid as Orviclo-400 mg Tablet 10's can cause dehydration and kidney damage.

Drug-Drug Interactions

verifiedApollotooltip
AciclovirCidofovir
Critical
AciclovirSirolimus
Severe

Drug-Drug Interactions

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AciclovirCidofovir
Critical
How does the drug interact with Orviclo-400 mg Tablet:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Orviclo-400 mg Tablet with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
AciclovirSirolimus
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Orviclo-400 mg Tablet with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Orviclo-400 mg Tablet with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
AciclovirTizanidine
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Concomitant use of Orviclo-400 mg Tablet with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Orviclo-400 mg Tablet with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir alafenamide
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Orviclo-400 mg Tablet with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Orviclo-400 mg Tablet with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Metrizamide in contrast with Orviclo-400 mg Tablet may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Orviclo-400 mg Tablet treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.
AciclovirTacrolimus
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Co-administration of Orviclo-400 mg Tablet with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Orviclo-400 mg Tablet with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.
AciclovirIodamide
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Iodamide contrast with Orviclo-400 mg Tablet may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Orviclo-400 mg Tablet treatment.
AciclovirAmphotericin b
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Orviclo-400 mg Tablet with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Orviclo-400 mg Tablet with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirEverolimus
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Orviclo-400 mg Tablet with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Orviclo-400 mg Tablet with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir disoproxil
Severe
How does the drug interact with Orviclo-400 mg Tablet:
Coadministration of Orviclo-400 mg Tablet with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Orviclo-400 mg Tablet with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcoholic beverages with Orviclo-400 mg Tablet 10's as it can make you dehydrated and may affect your sleep.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

  • Include turmeric or yellow mustard in your diet to avoid constipation caused by antiviral drugs and increase the intake of fluids to stay hydrated.

  • Take enough of Vitamin D and fresh air as it is known to improve the symptoms of herpes infection.

  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.

  • Eat a healthy and balanced diet, and make sure you sleep at least 8 hours a day for a speedy recovery.

  • If you are going in strong sunlight, please wear a lip balm SPF 15 or higher, and Orviclo-400 mg Tablet 10's makes you sensitive to UV and sunlight.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Orviclo-400 mg Tablet 10's Substitute

Substitutes safety advice
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Alcohol

Caution

Limit alcohol intake while using Orviclo-400 mg Tablet 10's to prevent any adverse effects.

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Pregnancy

Caution

Orviclo-400 mg Tablet 10's is a pregnancy Category B medicine. It is not known whether Orviclo-400 mg Tablet 10's will affect pregnant women or fetus or not. Hence, the intake of Orviclo-400 mg Tablet 10's should be only if prescribed and under medical supervision.

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Breast Feeding

Caution

Orviclo-400 mg Tablet 10's is a pregnancy Category B medicine. It is not known whether Orviclo-400 mg Tablet 10's will pass through the milk in breastfeeding women or not. Hence, Orviclo-400 mg Tablet 10's should only be taken if prescribed by a doctor and under medical supervision.

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Driving

Caution

Orviclo-400 mg Tablet 10's can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Safe if prescribed

Orviclo-400 mg Tablet 10's is safe if prescribed by a doctor. It is known not to interact with liver functioning.

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Kidney

Caution

Orviclo-400 mg Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Orviclo-400 mg Tablet 10's is safe if prescribed by a child specialist.

FAQs

Orviclo-400 mg Tablet 10's is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox.

Orviclo-400 mg Tablet 10's works by preventing the multiplication of viruses in human cells. As a result, this stops the proliferation of viruses and produces new viruses, slowly leading to the viral infection clearing up. Take Orviclo-400 mg Tablet 10's preferably first thing in the morning as generally it is taken after every 4 hours.

Orviclo-400 mg Tablet 10's is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox.

No, Orviclo-400 mg Tablet 10's should not be taken if you have HIV (Human Immuno Deficiency Syndrome). It can increase the risk of Thrombotic Thrombocytopenic Purpura (blood clot formation in small blood vessels).

No, Orviclo-400 mg Tablet 10's should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Orviclo-400 mg Tablet 10's, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

No, Orviclo-400 mg Tablet 10's does not cure herpes infection. Instead, it reduces pain and itching caused due to it and prevents a new sore formation.

Do not stop taking Orviclo-400 mg Tablet 10's without talking to your doctor. If you suddenly stop taking Orviclo-400 mg Tablet 10's, you may experience confusion, fever, mental state changes, or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

No, Orviclo-400 mg Tablet 10's is not known to affect contraception (condoms). Also, to avoid transmission of herpes infection as it is a sexually transmitted disease; please use any form of contraception.

Orviclo-400 mg Tablet 10's helps treat shingles and suppress its symptoms. It does not cure shingles.

Orviclo-400 mg Tablet 10's stops the spread of the herpes virus in the body. It may not stop the spread of the infection to other people. Practise safe sex and wash your hands regularly to prevent transmission of infection to others.

Serious side effects of Orviclo-400 mg Tablet 10's are blood in the urine, chest pain or palpitations, hair loss, kidney problems, low blood pressure, lymph node swelling, seizures, serious skin reactions, and mental health changes such as agitation or aggression, confusion, depression, hallucinations, and psychotic symptoms.

Yes, elderly patients need to be more careful while taking Orviclo-400 mg Tablet 10's as they might be more sensitive to the side effects of this medicine.

Taking more than the recommended dose of Orviclo-400 mg Tablet 10's may cause an overdose. The symptoms of overdose include extreme tiredness, seizures (fits), change in the amount of urine, loss of consciousness and agitation. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Common side effects of Orviclo-400 mg Tablet 10's are headaches, feeling dizzy, feeling or being sick (nausea or vomiting), diarrhoea, rash, and skin sensitivity to sunlight. Most of these side effects of Orviclo-400 mg Tablet 10's are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Orviclo-400 mg Tablet 10's should be used during pregnancy or breastfeeding only if prescribed by the doctor. Please consult the doctor if you are pregnant, planning for pregnancy or breastfeeding.

Alcohol may not interfere with the working of Orviclo-400 mg Tablet 10's. However, limit alcohol intake while using Orviclo-400 mg Tablet 10's to prevent any adverse effects.

Patients with impaired immunity or having HIV may get resistant to Orviclo-400 mg Tablet 10's treatment. Inform the doctor if you have HIV or low immunity.

No, hair loss caused due to Orviclo-400 mg Tablet 10's is not permanent. It stops on discontinuing the medicine.

Country of origin

India

Manufacturer/Marketer address

No. 1065, Street No. 1, Haripur, Sector - 4,, Panchkula, 160022.
Other Info - ORV0032

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:36 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.4334.pdf
  2. https://www.nhs.uk/medicines/aciclovir/
  3. https://www.medicines.org.uk/emc/files/pil.9273.pdf

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