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  3. Ortidin 300mg Tablet

Ortidin 300mg Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Ortidin 300mg Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. It is also used to prevent and treat stomach ulcers. It contains Ranitidine, which helps reduce stomach acid. It may cause common side effects like headache, diarrhoea, constipation, and shortness of breath. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

RANITIDINE-300MG

Manufacturer/Marketer :

Ortin Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Ortidin 300mg Tablet

Ortidin 300mg Tablet is used to treat indigestion, heartburn and acid reflux. Ortidin 300mg Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Ortidin 300mg Tablet is also used to prevent and treat stomach ulcers.

Ortidin 300mg Tablet contains ranitidine, which helps reduce stomach acid by blocking the actions of the H2 receptor. It is responsible for the release of gastric acid secretion-extra gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Ortidin 300mg Tablet might have common side effects like headache, diarrhoea, constipation, and shortness of breath. These side effects are temporary and may be resolved after some time. However, if these side effects persist, contact your doctor.

Take this medication exactly as prescribed by your doctor. It would help if you kept taking medicine for as long as your doctor recommends. If you stop early, your symptoms may come back, and your condition may worsen.

It is recommended not to take Ortidin 300mg Tablet if you are allergic to any components present in Ortidin 300mg Tablet. If you are pregnant, planning to become pregnant, or are breastfeeding, you should not take this medication unless your doctor says it is necessary. Inform your doctor if you have stomach or intestinal cancer, liver problems, or will have an endoscopy in the future.

Uses of Ortidin 300mg Tablet

Ortidin 300mg Tablet used in the treatment of Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, and Peptic Ulcer. The detailed uses of Ortidin 300mg Tablet are as follows: 

  • Treatment of Heartburn: Ortidin 300mg Tablet used to treat heartburn and acid reflux by reducing excess stomach acid, providing relief from discomfort.
  • Management of Peptic Ulcers: Ortidin 300mg Tablet is involved in managing peptic ulcers by reducing stomach acid production and allowing ulcers to heal.
  • Gastroesophageal Reflux Disease (GERD): Ortidin 300mg Tablet helps to manage GERD by reducing severe acid reflux symptoms and preventing esophageal damage.
  • Prevention of Gastric Acid-related Issues: Ortidin 300mg Tablet can prevent gastric acid-related issues before surgeries or procedures, reducing the risk of complications.
  • Support in Treating Zollinger-Ellison Syndrome: Ortidin 300mg Tablet manages Zollinger-Ellison syndrome by decreasing excessive stomach acid production.

Directions for Use

  • Ortidin 300mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Ortidin 300mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it. Take Ortidin 300mg Tablet 30–60 minutes before food or drink that may cause indigestion.

Medicinal Benefits

  • Ortidin 300mg Tablet helps in reducing the excess amount of stomach acid.
  • In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger-Ellison Syndrome, in which the stomach makes an exceptionally high amount of acid.

How Ortidin 300mg Tablet Works

Ortidin 300mg Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall. It is responsible for the release of gastric acid secretion - excessive gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ortidin 300mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Ortidin 300mg Tablet

Do not take more than the prescribed dose of Ortidin 300mg Tablet as it may cause an overdose. The symptoms of overdose include lack of coordination, fainting or lightheadedness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • You should avoid taking Ortidin 300mg Tablet if you are allergic to Ortidin 300mg Tablet or H2 receptor blockers, have gastric cancer, or have liver disease.
  • If you are a pregnant woman or nursing mother, do not consume Ortidin 300mg Tablet without first consulting your doctor. 
  • Ortidin 300mg Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), or anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines.
  • Intake of Ortidin 300mg Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous), immediately consult the doctor.

Drug-Drug Interactions

verifiedApollotooltip
RanitidineRilpivirine
Severe
RanitidineAtazanavir
Severe

Drug-Drug Interactions

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RanitidineRilpivirine
Severe
How does the drug interact with Ortidin 300mg Tablet:
Coadministration of Rilpivirine with Ortidin 300mg Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of Rilpivirine.

How to manage the interaction:
Although taking Ortidin 300mg Tablet together with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. To reduce the chance of interaction, take Ortidin 300mg Tablet at least 12 hours before or 4 hours after taking rilpivirine. Do not discontinue any medicine without consulting a doctor.
RanitidineAtazanavir
Severe
How does the drug interact with Ortidin 300mg Tablet:
Taking atazanavir with Ortidin 300mg Tablet can reduce the effectiveness of atazanavir.

How to manage the interaction:
Although taking Ortidin 300mg Tablet together with Atazanavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineGefitinib
Severe
How does the drug interact with Ortidin 300mg Tablet:
Coadministration of Gefitinib with Ortidin 300mg Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of gefitinib

How to manage the interaction:
Taking Gefitinib with Ortidin 300mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that gefitinib is either taken 6 hours before or 6 hours after Ortidin 300mg Tablet to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
RanitidinePazopanib
Severe
How does the drug interact with Ortidin 300mg Tablet:
Using Pazopanib with Ortidin 300mg Tablet can reduce the effectiveness of pazopanib

How to manage the interaction:
Although taking Ortidin 300mg Tablet together with Pazopanib can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RanitidineDasatinib
Severe
How does the drug interact with Ortidin 300mg Tablet:
Taking Ortidin 300mg Tablet and Dasatinib together reduces the effectiveness of Dasatinib.

How to manage the interaction:
Although taking Ortidin 300mg Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience any unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineLoperamide
Severe
How does the drug interact with Ortidin 300mg Tablet:
Coadministration of loperamide with Ortidin 300mg Tablet may significantly increase the blood levels of loperamide. This can increase the risk of serious side effect like irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Ortidin 300mg Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
RanitidineMesalazine
Severe
How does the drug interact with Ortidin 300mg Tablet:
Co-administration of Ortidin 300mg Tablet with Mesalazine can decrease the levels of Mesalazine, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalazine with Ortidin 300mg Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
RanitidineCefditoren
Moderate
How does the drug interact with Ortidin 300mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
v
RanitidineCefuroxime
Moderate
How does the drug interact with Ortidin 300mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
vv

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid acid or heartburn triggering foods or drinks, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, raise your bedhead so your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backflowing through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid from flowing back into the food pipe.
  • Include high fibre-containing foods like berries, cherries, leafy green veggies (kale, spinach), and black peppers.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pylori infections.
  • Avoid continuous sitting, as it can increase stomach acid production. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Ortidin 300mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Drinking alcohol with Ortidin 300mg Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So try to avoid consuming alcohol.

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Pregnancy

Consult your doctor

Ortidin 300mg Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Ortidin 300mg Tablet should be used in nursing women only if clinically needed, and the benefits outweigh the risks.

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Driving

Caution

Ortidin 300mg Tablet has no or negligible influence on the ability to drive and use machines. In some cases, Ortidin 300mg Tablet may cause dizziness and sleep. If you observe these symptoms, do not drive or operate machinery until you feel better.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Consult your doctor

If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Safe if prescribed

The dose needs to be adjusted based on your child’s weight.

Have a query?

FAQs

Ortidin 300mg Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Ortidin 300mg Tablet is also used to prevent and treat stomach ulcers. Often Ortidin 300mg Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Ranitidine belongs to a class of drugs known as H2 receptor antagonists (gastrointestinal agents). Ortidin 300mg Tablet works by lessening the quantity of acid produced in your stomach.

You can take Ortidin 300mg Tablet with or without food. However, if you get symptoms whenever you eat or drink, take your medicine 30 minutes before having a drink, snack, or meal.

Ortidin 300mg Tablet starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.

Ortidin 300mg Tablet may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, and difficulty in breathing. Inform your doctor in case you notice any of these side effects.

No, Ortidin 300mg Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.

The duration of the Ortidin 300mg Tablet treatment depends on your specific condition and the doctor's recommendation.

Ortidin 300mg Tablet is a common treatment for gastritis. However, if you have gastritis, it's essential to consult with a healthcare professional before using Ortidin 300mg Tablet, especially for the long term. They can provide an accurate diagnosis and recommend appropriate alternative therapies.

Ortidin 300mg Tablet typically starts working within 30 minutes to 1 hour. However, achieving complete symptom relief may take several days of consistent use.

No, the Ortidin 300mg Tablet is not used for loose motion.

Ortidin 300mg Tablet typically starts working within 30 minutes. Individual responses may vary from person to person.

Ortidin 300mg Tablet is a widely used over-the-counter antacid medication and is generally very well tolerated.

Yes, it can be used in children; the dose must be adjusted based on your child's weight. If your child is experiencing heartburn, acid reflux, or other digestive issues, it's important to consult with a paediatrician. They can provide an accurate diagnosis and recommend appropriate alternative treatments that are safe and effective for children.

Yes, Ortidin 300mg Tablet can cause constipation in some people. While constipation is not a common side effect of Ranitidine, it can occur in some individuals.

Ortidin 300mg Tablet contains Ranitidine (a histamine-2 (H2) receptor blocker), whereas PAN 40 contains Pantoprazole (proton-pump inhibitors). Both are used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.

Do not take Ortidin 300mg Tablet for longer than two weeks unless your doctor tells you to. Long-term use of Ranitidine may increase the risk of side effects. If you're taking Ranitidine, discussing this with your doctor and exploring alternative options is essential.

Take Ortidin 300mg Tablet with or without food as directed by your doctor.

Yes, Ranitidine was once considered an effective medication for treating conditions like heartburn, acid reflux, and ulcers. It works by reducing the amount of acid produced by the stomach.

To ensure safe medication use, always follow your doctor's instructions, read medication labels carefully, take medications at the right time, inform your doctor about allergies or medical conditions, report any side effects, store medications properly, and dispose of them safely. Avoid self-medication, combining medications without consulting your doctor, stopping medications suddenly, sharing medications, and taking expired medications. If you have any questions or concerns, consult with your healthcare provider.

Drinking alcohol with Ortidin 300mg Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So, try to avoid consuming alcohol.

Ranitidine and omeprazole are both used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.

Country of origin

India

Manufacturer/Marketer address

QU-140/2-3, BAGBERA HAUSING COLONY RD NO-4 Jamshedpur Purba Singhbhum JH 831002 IN
Other Info - OR18598

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 7, 2025 | 9:07 AM IST

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Reference

  1. https://www.drugs.com/ranitidine.html
  2. https://medlineplus.gov/druginfo/meds/a601106.html
  3. https://www.medicines.org.uk/emc/search?q=%22Ranitidine%22
  4. https://www.nhs.uk/medicines/ranitidine/
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