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compositionComposition:ORNIDAZOLE-500MG
prescription
Prescription Medicine
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Ornixi 500 Tablet is used to treat infections caused by protozoans and bacteria. It is used to treat amoebiasis, chlamydiosis, giardia infection, trichomonas infection, vaginal, urinary tract, intestinal and post-operative infections. It contains Ornidazole, which works by damaging the DNA of the infection-causing agent and inhibiting its growth. Thereby, it treats infections. In some cases, it may cause common side effects such as nausea, vomiting, headache, dizziness, and taste disturbances. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ORNIDAZOLE-500MG

Manufacturer/Marketer :

Zeelab Pharmacy Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Ornixi 500 Tablet

Ornixi 500 Tablet is a prescription medication used to treat a variety of infections caused by certain bacteria and tiny organisms called protozoa. It is commonly prescribed for infections in the gut, reproductive system, and other parts of the body. By clearing these harmful organisms, it helps resolve symptoms like diarrhoea, stomach pain, and unusual discharge.

To get the best results, you should take Ornixi 500 Tablet exactly as prescribed by your doctor, usually once or twice a day at the same times each day. It is best to take this medicine after meals to help prevent stomach upset and ensure proper absorption. During your treatment, drinking plenty of clean water and eating plain, easily digestible foods can support your recovery.

While taking Ornixi 500 Tablet, you might experience mild side effects such as nausea, a metallic taste in your mouth, or temporary dizziness. These symptoms usually go away on their own as your body adjusts. However, if you experience severe allergic reactions, skin rashes, or numbness and tingling in your hands or feet, stop taking the medication and contact your healthcare provider immediately.

Before starting Ornixi 500 Tablet, it is important to discuss your medical history with your doctor, especially if you have a history of liver damage, kidney disease, or nervous system disorders. Do not take this if you have a known allergy to similar anti-infective medications.

This medicine can interact negatively with alcohol, causing severe stomach pain, nausea, and a rapid heartbeat, so you must avoid alcohol completely during treatment and for at least three days after your final dose. Please consult your doctor before using Ornixi 500 Tablet if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient, as special precautions may be needed.

Uses of Ornixi 500 Tablet

Ornixi 500 Tablet may be prescribed to treat the following infections:

  • Amoebiasis: Ornixi 500 Tablet helps clear amoebic infections in the intestines and liver, stopping severe diarrhoea and abdominal cramps.
  • Giardiasis: This medicine eliminates parasites in the gut responsible for watery diarrhoea, bloating, and stomach discomfort.
  • Trichomoniasis: It treats this common sexually transmitted infection in both men and women, clearing vaginal or urethral discharge and irritation.
  • Anaerobic bacterial infections: Ornixi 500 Tablet targets and destroys harmful anaerobic bacteria causing infections in the gums, bones, pelvis, or abdomen.
     

Key Benefits

Ornixi 500 Tablet helps treat bacterial and parasitic infections by eliminating the microorganisms responsible for the infection. It provides relief from symptoms while helping prevent the infection from worsening.

  • Treats Bacterial and Parasitic Infections: Helps eliminate infection-causing bacteria and parasites from the body.
  • Relieves Digestive Symptoms: Helps reduce abdominal pain, cramps, diarrhoea, and other symptoms associated with intestinal infections.
  • Promotes Faster Recovery: By controlling the underlying infection, it supports quicker healing and restoration of normal health.
  • Prevents Infection Progression: Helps stop the spread of infection and reduces the risk of complications.
  • Improves Daily Comfort: Relief from infection-related symptoms may help restore energy levels and allow you to resume normal daily activities more comfortably.
     

Directions for Use

  • Ornixi 500 Tablet should be taken after a meal or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Ornixi 500 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Ornixi 500 Tablet Works

Ornixi 500 Tablet contains ornidazole, which works by directly attacking the genetic material of the harmful bacteria and parasites causing your infection. Once you swallow the medicine, it enters the cells of these disease-causing organisms. Inside these cells, the medicine is converted into an active form that damages their DNA, which is essential for their survival and reproduction. By breaking down this genetic material, Ornixi 500 Tablet stops the bacteria and parasites from multiplying and spreading. Without the ability to grow or repair themselves, the invading organisms quickly die off. This allows your body's natural immune system to clear the remaining infection and begin the healing process.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Ornixi 500 Tablet and for three days after the treatment.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Ornixi 500 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Ornixi 500 Tablet if you are breastfeeding. Your doctor will decide if Ornixi 500 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Ornixi 500 Tablet may cause dizziness and sleepiness. So, drive only if you are alert.

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Liver

Caution

Please consult your doctor before taking Ornixi 500 Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Ornixi 500 Tablet.

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Children

Safe if prescribed

Ornixi 500 Tablet should be given to children in the dose and duration advised by the doctor.

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Heart

Safe if prescribed

Ornixi 500 Tablet is generally safe for use in cardiac patients if prescribed by the doctor.

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Geriatrics

Caution

Ornixi 500 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Ornixi 500 Tablet

If you accidentally take more than your prescribed dose of Ornixi 500 Tablet, you may experience symptoms like severe dizziness, nausea, vomiting, or muscle tremors. Seek immediate medical attention or contact your local poison control centre right away. Bring the remaining medication or packaging with you so the healthcare providers know exactly what you took.

Diet & Lifestyle Advise

  • Stay well-hydrated: If you are treating a gut infection that causes diarrhoea, drink plenty of fluids such as clear broths, oral rehydration solutions, and clean water to prevent dehydration.
  • Eat bland, easy-to-digest foods: Stick to simple foods like bananas, rice, applesauce, and plain toast to give your digestive system a break while healing.
  • Avoid dairy products temporarily: Some people find that milk, cheese, and yoghurt can worsen diarrhoea or stomach cramping during an active gut infection.
  • Maintain excellent hygiene: Wash your hands thoroughly with soap and water after using the bathroom and before eating to prevent spreading parasites or bacteria to others.
  • Avoid alcohol completely: Do not consume any alcohol during your treatment and for at least 72 hours after your final dose to prevent a severe chemical reaction.
     
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How Soon It Starts Working

The time required for Ornixi 500 Tablet to start to work: The time required for Ornixi 500 Tablet to show its action is unknown. The time for which the effects of Ornixi 500 Tablet last: The effect of Ornixi 500 Tablet lasts for 24 hours.

What if you forget to take Ornixi 500 Tablet

If you miss a dose of Ornixi 500 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a forgotten one, as this can increase your risk of experiencing side effects.

Storage

•Store Ornixi 500 Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original blister pack or container to protect it from direct sunlight and excess moisture.

Drug Warnings

  • Avoid driving and operating machinery: Ornixi 500 Tablet can make you feel dizzy, sleepy, or less alert. Do not drive or use heavy machinery until you know how this medicine affects you.
  • Check packaging before use: Always inspect the blister packaging before taking your dose. Do not use the medicine if the seal is broken, torn, or if the tablets show signs of discolouration or damage.
  • Complete the full course: Even if your symptoms clear up completely in a couple of days, finish the entire bottle or prescription. Stopping early can lead to a stronger, treatment-resistant infection.
  • Inform other healthcare providers: Let your dentist, surgeon, or any other doctor know that you are currently taking Ornixi 500 Tablet, especially if you are scheduled for any blood tests or medical procedures.
  • Watch for nerve symptoms: If you feel any unusual numbness, tingling, or burning sensations in your limbs, contact your doctor immediately, as this may require a change in treatment.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Ornixi 500 Tablet:

  • Blood thinners: Ornixi 500 Tablet can increase the effect of blood thinners, which may elevate your risk of bleeding. Your doctor may need to adjust your blood thinner dose.
  • Lithium: Taking this medicine with lithium can raise lithium levels in your blood, increasing the risk of lithium toxicity.
  • Certain muscle relaxants: It may prolong the muscle-relaxing effects of medications used during surgeries.

Drug-Food Interactions

Avoid or use caution with the following foods and beverages while taking Ornixi 500 Tablet:

  • Alcohol: Consuming alcohol or alcohol-containing products while taking Ornixi 500 Tablet can trigger a severe reaction, leading to intense nausea, hot flushes, rapid heartbeats, and vomiting.

Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Ornixi 500 Tablet:

  • Liver Disease: If you have severe liver damage, your body may process this medication much slower, which can cause the drug to build up and increase the risk of side effects.
  • Nervous System Disorders: People with conditions like epilepsy, multiple sclerosis, or active nerve diseases should use Ornixi 500 Tablet with extreme caution, as it can worsen neurological symptoms.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI-INFECTIVE AND ANTIPROTOZOALS]

FAQs

Ornixi 500 Tablet is used to treat infections caused by protozoans and bacteria. It is used to treat amoebiasis, chlamydiosis, giardia infection, trichomonas infection, vaginal, urinary tract, intestinal and post-operative infections.
Ornixi 500 Tablet works by damaging the DNA of the infection-causing agent and inhibiting its growth. Thereby, it treats infections.
Take the missed dose as soon as possible. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Do not take a double dose to make up for the missed dose.
Do not take Ornixi 500 Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.
No, you must completely avoid alcohol while taking this medicine and for at least three days after your last dose. Combining them can cause a severe reaction with symptoms like intense headache, nausea, rapid heartbeat, and vomiting. Talk to your doctor or pharmacist if you have questions about specific products containing alcohol.
Ornixi 500 Tablet is generally not recommended during pregnancy, especially during the first trimester, unless your doctor decides it is absolutely necessary. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the risks and benefits.
If you vomit within 30 minutes of taking your tablet, the medicine may not have been fully absorbed, and you may need to take another dose. However, if you vomit hours after taking it, do not take an extra tablet. Talk to your doctor or pharmacist for specific advice based on your situation.
Yes, experiencing a temporary metallic or bitter taste in your mouth is a common and harmless side effect of this medicine. It should go away completely once you finish your prescribed treatment. Drinking water or chewing sugar-free gum may help ease this symptom. Talk to your doctor if it becomes highly uncomfortable.
Yes, it is a type of anti-infective medicine that works against specific anaerobic bacteria and certain parasites (protozoa). It is not effective against viral infections like the common cold or flu. Talk to your doctor to ensure you are using the correct treatment for your specific infection.
While dairy does not directly stop the absorption of this medicine, gut infections themselves can make you temporarily sensitive to lactose. It is often best to avoid heavy dairy consumption until your stomach has completely recovered. Talk to your doctor or pharmacist for personalised dietary advice.
No. You should complete the full course of Ornixi 500 Tablet exactly as prescribed, even if you start feeling better, to ensure the infection is completely treated and to help reduce the risk of antibiotic resistance. If your symptoms do not improve after completing the prescribed course, or if they worsen during treatment, contact your doctor. This may indicate that a different treatment or further evaluation is needed.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MIMS Drug Reference Compendium. Ornidazole Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Nbk557718 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Lactmed.Ornidazole [[Accessed on 11Jun].2019]Check here
  4. David G. Bailey, George Dresser and J. Malcolm O. Arnold, MB. National Library of Medicine (NIH). Grapefruit–medication interactions: Forbidden fruit or avoidable consequences. [Revised in 18th October 2018] [Accessed on 3rd May 2022]Check here
  5. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG). National Library of Medicine (NIH). Using medication: Using antibiotics correctly and avoiding resistance. [Revised in 13th December 2013] [Accessed on 3rd May 2022]Check here
  6. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 3rd May 2022]Check here
  7. Dr Reddy's Laboratories Limited. Ofloxacin tablet. DailyMed; National Library of Medicine; National Institute of Health. [Revised in December 2018] [Accessed on 3rd May 2022]Check here

Country of origin

India

Manufacturer/Marketer address

SCF-509, 1st Floor, Motor Market, Manimajra, Chandigarh (India)-160101
Other Info - OR14745
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