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compositionComposition:RELUGOLIX-120MG
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Orgonist Tablet 10's is used to treat advanced prostate cancer in adult men. It works by reducing testosterone production in the body, which can help slow or stop the growth of prostate cancer cells that require testosterone to grow. The common side effects of Orgonist Tablet 10's include hot flashes, diarrhoea, constipation, fatigue, and muscle and joint pain. Before starting Orgonist Tablet 10's, inform the doctor if you are taking other medicines or have pre-existing medical conditions.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

RELUGOLIX-120MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Orgonist Tablet 10's

Orgonist Tablet 10's is a prescription medication designed to treat adults with advanced prostate cancer. This medicine acts by lowering specific hormones in the body to help control the growth of cancer cells. It is a critical component of hormone therapy that helps slow down the progression of the disease.

It is important to take Orgonist Tablet 10's consistently every single day at the same time to ensure it works properly. You can take this tablet with or without food, but you must swallow it whole without chewing. Incorporating a heart-healthy diet and routine physical exercise can help your body respond better to the treatment and manage changes in your physical health.

While taking this medicine, some patients may experience mild side effects like hot flashes, joint pain, or temporary fatigue. However, you must contact your doctor immediately if you experience serious side effects such as severe chest pain, sudden shortness of breath, or signs of liver problems like yellowing skin.

Do not take this if you have had a severe allergic reaction to any of its components. Before starting, talk to your doctor if you have a history of heart conditions, heart rhythm abnormalities, or kidney and liver disease.

This medicine can interact with other drugs that affect liver enzymes or your heart's electrical rhythm, so always inform your healthcare provider of all products you use. While this medicine is not intended for use in women, male patients with partners who can become pregnant must use effective birth control during treatment. Elderly individuals should consult their doctor to ensure their heart health is carefully monitored during therapy.

Uses of Orgonist Tablet 10's

Your doctor may prescribe Orgonist Tablet 10's to help manage the following conditions:

  • Advanced prostate cancer: Orgonist Tablet 10's helps by blocking the signals in your body that trigger testosterone production. Since prostate cancer cells rely on testosterone to grow and multiply, lowering this hormone to very low levels helps slow down the spread of the disease and shrink tumors.
     

Key Benefits

Orgonist Tablet 10's provides meaningful, real-world relief for individuals managing advanced prostate cancer. Because it is a daily oral pill rather than an injection, it allows patients to manage their treatment comfortably from home without frequent doctor visits.

  • Rapid hormone reduction: It works quickly to drop testosterone to castrate levels, starting within the first few days of treatment.
  • No initial testosterone spike: Unlike some injectable hormone therapies, this medicine does not cause a temporary surge in testosterone when you start, avoiding a temporary worsening of symptoms.
  • Avoids needle pain: Being an oral tablet, it eliminates the discomfort, bruising, and inconvenience associated with regular hormone injections.
  • Faster recovery: If you ever need to stop the medication, your natural hormone levels can recover much faster than they would after long-acting injections.
Side effects of Orgonist Tablet

Directions for Use

  • Orgonist Tablet 10's can be taken with or without food as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Orgonist Tablet 10's as a whole with a glass of water.
  • Do not break, crush or chew it.

How Orgonist Tablet 10's Works

Orgonist Tablet 10's is a gonadotropin-releasing hormone (GnRH) receptor antagonist. It works by targeting and blocking specific receptor sites in the pituitary gland, which is a regulatory center in the brain. Normally, these receptors receive signals that prompt the release of other hormones, which in turn tell the testicles to produce testosterone. By blocking these receptors, Orgonist Tablet 10's cuts off the communication chain. This stops the production of testosterone in the body, effectively starving the prostate cancer cells of the hormone they need to grow.
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Alcohol

Consult your doctor

It is not known if alcohol affects Orgonist Tablet 10's. Consult your doctor for guidance.

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Pregnancy

Unsafe

It is unsafe to use Orgonist Tablet 10's during pregnancy as it may harm your unborn baby and cause loss of pregnancy (miscarriage). However, Orgonist Tablet 10's is not recommended for use in women as safety and effectiveness are not established.

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Breast Feeding

Unsafe

It is not known if Relugolix passes into your breast milk. However, Orgonist Tablet 10's is not recommended for use in women as safety and effectiveness are not established.

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Driving

Caution

Orgonist Tablet 10's may cause tiredness and dizziness. Do not drive unless you are alert.

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Liver

Caution

Exercise caution before taking Orgonist Tablet 10's in case of pre-existing liver disease. Please consult the doctor if you have any concerns.

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Kidney

Caution

Orgonist Tablet 10's should be taken with caution if you have severe kidney disease. Consult your doctor if you have kidney problems.

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Children

Unsafe

Orgonist Tablet 10's is not recommended for use in children below 18 years, as safety and effectiveness are not established.

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Heart

Caution

Orgonist Tablet 10's may increses the risk of herart problems. Therefore, please inform your doctor if you have any pre-existing heart problems before prescribing Orgonist Tablet 10's.

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Geriatrics

Safe if prescribed

Orgonist Tablet 10's is generally considered safe for geriatric patients when used as directed by the doctor. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Orgonist Tablet 10's

If you take too much of this medicine, seek immediate emergency medical care. Go to the nearest emergency room if you show signs of severe dizziness, fainting, or chest pain.

Diet & Lifestyle Advise

  • Protect your bones: Since lowering testosterone can reduce bone strength, eat calcium-rich foods like leafy greens, fortified foods, and nuts. Talk to your doctor about taking calcium and vitamin D supplements.
  • Stay active: Engage in regular, low-impact weight-bearing exercises such as brisk walking, resistance band workouts, or light weightlifting to help preserve muscle mass and protect your bone density.
  • Follow a heart-healthy diet: Maintain a balanced diet low in saturated fats and high in vegetables, whole grains, and lean proteins to manage potential changes in cholesterol and blood sugar levels during hormone therapy.
  • Limit caffeine and spicy foods: These can trigger or worsen hot flashes. Staying hydrated with cool water can also help you manage temperature changes.
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How Soon It Starts Working

The time required for Orgonist Tablet 10's to start to work: The time required for Orgonist Tablet 10's to show its action is unknown. The time for which the effects of Orgonist Tablet 10's last: The duration of action for Orgonist Tablet 10's is unknown.

What if you forget to take Orgonist Tablet 10's

If you miss a dose, take it as soon as you remember if it is within 12 hours of your scheduled time. If it has been more than 12 hours since your missed dose, skip the missed tablet completely and take your next dose at your regular scheduled time. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Orgonist Tablet 10's at room temperature between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Track your heart rhythm: This medicine can alter the electrical rhythm of your heart. Alert your healthcare provider immediately if you experience palpitations, severe dizziness, or a feeling that your heart is skipping a beat.
  • Use effective birth control: Male patients with female partners who can become pregnant must use highly effective birth control during treatment and for at least 2 weeks after stopping this medicine.
  • Attend routine blood tests: Your doctor will perform regular blood tests to check your liver function and monitor your hormone levels.
  • Check your tablets: Always inspect your tablets before taking them; do not take any tablets that look chipped, broken, or discoloured.
  • Never double up: If you miss a dose beyond the 12-hour window, skip it entirely—never take a double dose to compensate.

Drug-Drug Interactions

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  • P-gp Inhibitors: Medicines that block the P-glycoprotein transporter (such as certain heart medications or antifungal drugs) can increase the amount of Orgonist Tablet 10's in your blood, making side effects more likely.
  • P-gp Inducers: Medicines that increase P-glycoprotein activity (like certain seizure medications or rifampin) can lower the levels of Orgonist Tablet 10's, making your treatment less effective.
  • Heart Rhythm Drugs: Combining this medicine with drugs that affect your heart's electrical intervals can increase the risk of serious irregular heartbeats.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Grapefruit products: Avoid eating grapefruit or drinking grapefruit juice in large quantities, as it can affect how your body breaks down this medication and may increase the risk of side effects.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Orgonist Tablet 10's belongs to the group of medications called gonadotropin-releasing hormone (GnRH) receptor antagonists. It is used for the treatment of advanced prostate cancer in adult men.
Orgonist Tablet 10's contains Relugolix, which works by blocking the production of testosterone, a hormone that is required by the prostate cancer cells to grow. Thereby, it helps slow or stop the growth and spread of advanced prostate cancer.
Seek immediate medical attention if you experience symptoms of QT prolongation (changes in the electrical activity of the heart), such as dizziness, fainting, palpitations, or chest pain. Watch for signs of allergic reactions, including swelling, trouble breathing, or rash. Additionally, seek help if you have sudden numbness, confusion, vision loss, or trouble walking.
Orgonist Tablet 10's may cause diarrhoea as a common side effect. If you experience this side effect, drink plenty of fluids to prevent dehydration, eat non-spicy meals, and take probiotics. Consult your doctor if diarrhoea persists. Do not take antidiarrheal medications on your own.
The common side effects of Orgonist Tablet 10's include hot flashes, decreased sexual desire, weight gain, muscle pain, joint pain, diarrhoea, constipation, fatigue, difficulty falling asleep or staying asleep, depression, and enlargement of the breast. Consult the doctor if any of these side effects persist or worsen.
Yes, Orgonist Tablet 10's may cause fertility problems in males, affecting your ability to father children. Consult the doctor if you have any concerns.
No, this medicine may harm your unborn baby and cause loss of pregnancy (miscarriage) if used during pregnancy. Orgonist Tablet 10's is indicated for use in adult men. It is not recommended for use in women as the safety and effectiveness have not been established.
Yes, males with female partners of reproductive potential should use contraception (effective birth control) during treatment with Orgonist Tablet 10's and for 2 weeks after the last dose.
There is no direct drug interaction between alcohol and Orgonist Tablet 10's. However, alcohol can worsen side effects like hot flashes, fatigue, and dehydration, and can put extra stress on your liver. Talk to your doctor or pharmacist about safe alcohol limits during your treatment.
No, you can take Orgonist Tablet 10's with or without food. The most important thing is to take your tablet at the same time each day to maintain consistent medicine levels in your body. Talk to your doctor or pharmacist if you struggle to find a routine.
If you throw up after taking your tablet, do not take another dose on that day. Simply wait and take your next dose at your regularly scheduled time the following day. Talk to your doctor if you experience frequent nausea or vomiting.
No, Orgonist Tablet 10's is not a cure for prostate cancer, but it is highly effective at controlling and managing advanced prostate cancer. By rapidly reducing the testosterone that cancer cells need to grow, it helps slow down or stop the progression of the disease. Talk to your doctor about your long-term treatment plan.
Lowering your testosterone levels over time can weaken your bones and increase the risk of fractures or osteoporosis. Your doctor may monitor your bone density and suggest calcium or vitamin D supplements to help keep your bones strong. Talk to your doctor about protective bone therapies.
Hot flashes are a common side effect of hormone reduction. You can manage them by dressing in layers, using fans, keeping your bedroom cool, and avoiding triggers like spicy foods, alcohol, and hot beverages. Talk to your doctor if hot flashes are severe or disrupt your sleep.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ORG0292
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