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compositionComposition:OPIPRAMOL DIHYDROCHLORIDE-50MG
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Prescription Medicine
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Opipran-50 Tablet is used to treat anxiety disorder. It is also used to treat somatic disturbances. It contains Opipramol dihydrochloride, which works by increasing the levels of certain chemical messengers in the brain that help in regulating mood and behaviour. As a result, a person can perform daily activities with more productivity and also improve quality of life. It may cause side effects such as nasal congestion (stuffy nose), dryness in the mouth, fatigue, hypotension (decreased blood pressure), orthostatic hypotension (sudden lowering of blood pressure on standing), drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OPIPRAMOL DIHYDROCHLORIDE-50MG

Manufacturer/Marketer :

Ryon Pharma

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Opipran-50 Tablet

Opipran-50 Tablet is an oral prescription medication primarily used to treat generalized anxiety disorder (GAD) and somatoform disorders (conditions where emotional distress shows up as physical symptoms such as stomach discomfort, muscle tension, or a racing heartbeat). It helps calm an overactive nervous system, allowing you to manage persistent worry, tension, and related physical discomforts. By addressing both the mental and physical sides of anxiety, it supports a steadier, more balanced daily routine.

For this medication to work effectively, it must be taken consistently and exactly as prescribed by your doctor. You can take it with or without food, though taking it with a glass of water at the same times each day helps establish a reliable routine. Combining this treatment with daily lifestyle adjustments such as reducing caffeine intake and practicing gentle relaxation exercises can significantly support your results.

While most people tolerate this medicine well, some may experience mild side effects like a dry mouth, light drowsiness, or temporary tiredness. These symptoms usually improve as your body adjusts to the medication. However, if you notice serious issues such as a yellowing of your skin or eyes, an unusually fast heartbeat, or a severe skin rash, you should stop taking the medicine and consult your doctor immediately.

Do not take this if you have a history of serious heart conditions, such as heart block, or if you suffer from severe liver damage or kidney issues. Before starting, tell your doctor if you have glaucoma, prostate issues, or difficulty urinating. Your healthcare provider will help determine if this medication is safe for your specific health profile.

This medicine can interact with alcohol, making you feel significantly more drowsy and less coordinated, so it is best to avoid drinking while on this treatment. It may also interact with other prescription drugs, particularly those that affect the nervous system or blood pressure. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, always consult your doctor before using Opipran-50 Tablet .

Uses of Opipran-50 Tablet

Opipran-50 Tablet is used in the treatment of anxiety disorders and somatoform disorders. Its uses include:

  • Generalized Anxiety Disorder (GAD): Helps reduce excessive worry, nervousness, restlessness, and persistent anxiety.
  • Somatoform Disorders: Helps relieve physical symptoms related to emotional distress, such as muscle tension, stomach discomfort, or a racing heartbeat.

Key Benefits

When taken regularly as prescribed, Opipran-50 Tablet may help:

  • Reduce persistent worry, nervousness, and feelings of tension.
  • Relieve physical symptoms associated with anxiety, including muscle tightness, stress-related discomfort, and palpitations.
  • Improve daily functioning and quality of life.
  • Promote better sleep by reducing anxiety-related restlessness.
  • Support long-term emotional well-being when used alongside healthy lifestyle habits and, where appropriate, psychological therapy.
Side effects of Opipran-50 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Drink plenty of water to stay hydrated.
  • Eat small meals throughout the day to keep your energy up.
  • Add salt to your food if your doctor recommends it.
  • Wear special stockings that help improve blood flow.
  • Sleep with your head slightly elevated.
  • Talk to a doctor if you often feel dizzy or lightheaded when standing up.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

Directions for Use

To get the most benefit from Opipran-50 Tablet :

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it unless advised by your doctor.
  • You can take it with or without food, preferably at the same time every day.
  • Follow your doctor's prescribed dose exactly. Do not change the dose or stop taking the medicine without medical advice.

How Opipran-50 Tablet Works

Opipran-50 Tablet works differently from many traditional antidepressants. It mainly acts on sigma-1 receptors, which help regulate the body's response to stress and anxiety. It also affects histamine, serotonin, and dopamine receptors, helping reduce anxiety, promote calmness, and relieve physical symptoms such as muscle tension or a racing heartbeat. These combined actions help improve emotional well-being over time while also producing a calming effect in many people.
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Alcohol

Unsafe

Avoid consumption of alcohol with Opipran-50 Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Caution

Opipran-50 Tablet is a Category C pregnancy drug, and safety is unknown. Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Opipran-50 Tablet is excreted in human milk. Please consult a doctor before using Opipran-50 Tablet while breastfeeding.

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Driving

Unsafe

Opipran-50 Tablet may cause dizziness, double vision, or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Opipran-50 Tablet .

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Liver

Caution

Take Opipran-50 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Opipran-50 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

The safety of Opipran-50 Tablet in children is unknown. Please consult a doctor.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Opipran-50 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Opipran-50 Tablet .

What if I have taken an overdose of Opipran-50 Tablet

Seek emergency medical attention immediately if you take more than your prescribed dose. Symptoms may include severe drowsiness, confusion, rapid heartbeat, low blood pressure, dizziness, or seizures.

Diet & Lifestyle Advise

Making a few simple changes to your daily habits can help support your treatment and manage anxiety more effectively:

  • Limit caffeine and alcohol: Both caffeine and alcohol can trigger anxiety, disrupt your sleep patterns, and interfere with how your medication works.
  • Establish a regular sleep schedule: Going to bed and waking up at the same time each day helps stabilize your mood and reduces daytime fatigue.
  • Stay hydrated: Drinking plenty of water throughout the day can help ease mild side effects like dry mouth.
  • Practice relaxation techniques: Incorporate gentle activities like deep breathing, meditation, or walking into your routine to help manage stress naturally.
health query

Have a query?

How Soon It Starts Working

  • The time required for Opipran-50 Tablet to start to work: Opipran-50 Tablet ideally shows its action within 3.3 hours after administration.
  • The time for which the effects of Opipran-50 Tablet last: The effect of Opipran-50 Tablet lasts for 6 to 11 hours.

What if you forget to take Opipran-50 Tablet

Take the missed dose as soon as you remember unless it is nearly time for your next dose. If so, skip the missed dose. Do not take two doses together.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do Not Stop Suddenly: If you have taken this medicine for a long time, your doctor may gradually reduce the dose to help minimise discontinuation effects or the return of anxiety symptoms.
  • Driving: Avoid driving or operating machinery until you know how the medicine affects you.
  • Medical Procedures: Tell your doctor, dentist, or surgeon that you are taking this medicine before any procedure.
  • Watch for Liver Problems: Contact your doctor if you notice yellowing of your skin or eyes, dark urine, or persistent nausea.
  • Follow-up: Attend regular follow-up appointments. Your doctor may review your progress after 4-6 weeks to assess how well the medicine is working and whether your dose needs adjustment.

Drug-Drug Interactions

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Drug-Drug Interactions

  • MAO Inhibitors: Do not take this medication with or shortly after taking monoamine oxidase inhibitors, as this can lead to severe, potentially dangerous spikes in blood pressure.
  • Nervous System Depressants: Combining Opipran-50 Tablet with sleeping pills, tranquilizers, or strong pain relievers can significantly increase drowsiness and slow down your reflexes.
  • Blood Pressure Medications: This medicine may alter the effects of certain blood pressure drugs, requiring your doctor to monitor your levels more closely.

Drug-Food Interactions

  • Alcohol: Avoid drinking alcohol while taking this medicine, as it can severely increase drowsiness, dizziness, and coordination issues.

Drug-Disease Interactions

  • Severe Liver or Kidney Disease: Do not take this medicine if you have severe liver damage or kidney issues, as your body may struggle to clear the medication.
  • Glaucoma and Urinary Retention: Use with caution or avoid if you have narrow-angle glaucoma or difficulty urinating, as this medication can worsen these conditions.
  • Heart Block: Do not take this medication if you have specific heart rhythm disorders like heart block.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANXIOLYTICS]

FAQs

Opipran-50 Tablet is used to treat anxiety disorder and somatic disturbances.
Opipran-50 Tablet contains an anti-anxiety medication, Opipramol (a tricyclic anti-depressant), which is used to treat general anxiety. It works by increasing the levels of certain chemical messengers in the brain that help in regulating mood and behaviour.
No. Even if you feel better, do not stop taking this medication without your doctor's advice. Stopping the medicine suddenly may lead to discontinuation effects or a return of anxiety symptoms, especially after long-term use. Your doctor will advise you on how to reduce the dose gradually if treatment needs to be stopped.
Yes, you need to monitor your liver functions regularly. And also, as Opipran-50 Tablet is known to cause hypotension (low blood pressure), please monitor your blood pressure regularly.
Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness, or age-related health issues, which may require caution and an adjustment in the dose for patients receiving Opipran-50 Tablet . So, it is better to consult a doctor before taking this medicine.
Anxiety is a feeling of fear, worry, or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling, and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.
Opipran-50 Tablet may cause drowsiness. So, do not drive or operate heavy machinery while taking Opipran-50 Tablet . Also, do not consume alcohol as it might increase the sleepiness effect of Opipran-50 Tablet .
While it belongs to a chemical family often associated with antidepressants, it is primarily used to treat generalized anxiety and physical symptoms caused by emotional stress. Talk to your doctor to learn more about how it fits your specific treatment plan.
No, you should avoid alcohol while taking this medication. Alcohol can significantly increase drowsiness, dizziness, and impair your coordination. Talk to your doctor or pharmacist if you have concerns.
Some calming effects may be noticed within a few days, but it usually takes several weeks of consistent daily use to experience the full benefits. Talk to your doctor if you do not feel an improvement after a few weeks.
Mild changes in appetite or weight may occur in some people taking Opipran-50 Tablet , although not everyone experiences this side effect. Eating a balanced diet and staying physically active may help maintain a healthy weight. If you notice significant or unexpected weight changes, speak with your doctor.
Opipran-50 Tablet is generally not considered addictive or habit-forming when taken as prescribed. However, if it has been used for a long time, your body may become accustomed to the medicine. Because of this, your doctor may recommend reducing the dose gradually rather than stopping it suddenly to help minimise discontinuation effects or the return of anxiety symptoms.
Dry mouth is a common, mild side effect. You can manage it by sipping water frequently, chewing sugarless gum, or using ice chips. Talk to your doctor or pharmacist if the dry mouth persists or becomes severe.
You should only take this medicine during pregnancy if your doctor decides the benefits outweigh the risks. Always tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medication. Talk to your doctor to discuss your options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - OPI0055

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