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compositionComposition:IOHEXOL-300MG
prescription
Prescription Medicine
info
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Omnipaque 300 mg Injection is a contrast agent used in radiological procedures to enhance imaging clarity during diagnostic tests such as X-rays, CT scans, and angiograms. It improves visibility and helps provide detailed images of blood vessels, organs, and tissues. Some common side effects include diarrhea, nausea, vomiting, stomach pain, gas, back pain, sweating, and headache.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IOHEXOL-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Omnipaque 300 mg Injection

Omnipaque 300 mg Injection is a specialised diagnostic injection used to help doctors see internal organs, blood vessels, and tissues more clearly during imaging tests such as CT scans and X-rays. It works by temporarily changing the way X-rays pass through certain parts of your body, allowing clearer images to be produced for an accurate diagnosis. It is not used to treat any disease or symptom directly but serves as an important tool to help guide your medical care.

Because this medicine is given as a single injection or infusion during a scheduled medical procedure, you do not need to take it on a regular schedule. Before your scan, your healthcare team may ask you to avoid eating solid food for several hours, depending on the type of examination you are having. Drinking plenty of water before and after the procedure helps your kidneys remove the medicine from your body more efficiently.

Most people receive this injection without any serious problems. It is very common to experience a temporary feeling of warmth or flushing throughout your body or notice a metallic taste in your mouth shortly after the injection. These sensations are usually harmless and disappear within a few minutes. However, tell the medical team immediately if you develop hives, severe itching, difficulty breathing, swelling of your face or throat, or any other symptoms of an allergic reaction during or after the procedure.

Before receiving this injection, tell your doctor if you have kidney disease, diabetes, thyroid problems, asthma, heart disease, multiple myeloma, or a history of severe allergic reactions to contrast agents. Do not receive this medicine if you have previously experienced a severe, life-threatening allergic reaction to iohexol or another iodinated contrast agent unless your doctor decides the benefits outweigh the risks and appropriate precautions are in place.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, herbal products, and supplements you are taking before your scan. In particular, metformin may need to be temporarily stopped around the time of the procedure if you have reduced kidney function. Avoid becoming dehydrated before your scan because dehydration may increase the risk of kidney problems. If you are pregnant, breastfeeding, or an older adult, discuss the potential benefits and risks of this medicine with your doctor before the procedure.

Uses of Omnipaque 300 mg Injection

Your doctor may use Omnipaque 300 mg Injection to help with the following imaging procedures:

  • CT scan imaging: Helps highlight organs, blood vessels, and soft tissues during computed tomography (CT) scans, making abnormalities easier to detect.
  • Angiography: Helps show the inside of arteries and veins so doctors can identify narrowing, blockages, aneurysms, or other blood vessel problems.
  • Urography: Helps visualise the kidneys, ureters, and bladder to investigate kidney stones, tumours, urinary tract obstruction, or structural abnormalities.
  • Myelography: In selected cases, it is injected around the spinal cord to help identify slipped discs, nerve compression, or other spinal abnormalities during imaging.

Key Benefits

Omnipaque 300 mg Injection helps doctors obtain clear, detailed images that support accurate diagnosis and treatment planning.

  • Provides clearer diagnostic images: Improves the visibility of internal organs, blood vessels, and body tissues during imaging tests.
  • Supports accurate diagnosis: Helps doctors identify abnormalities such as blockages, tumours, bleeding, kidney stones, or other structural problems more precisely.
  • May reduce the need for more invasive procedures: Detailed imaging may help avoid exploratory surgery or other invasive diagnostic tests.
  • Helps guide appropriate treatment: Accurate imaging allows your healthcare team to plan the most suitable treatment based on reliable diagnostic information.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Omnipaque 300 mg Injection is administered by the doctor or healthcare professional.
  • Do not self-administer.

How Omnipaque 300 mg Injection Works

Omnipaque 300 mg Injection is an iodinated contrast agent that temporarily makes certain parts of your body appear more clearly during X-rays and CT scans. After it is injected, the medicine travels through your bloodstream or collects in the area being examined. Because it absorbs X-rays more effectively than surrounding body tissues, the treated areas appear brighter on the images, allowing doctors to distinguish normal structures from abnormalities more easily. Once the imaging procedure is complete, the medicine is removed naturally from your body. In most people with normal kidney function, it is filtered by the kidneys and passed out in the urine over the following 24 hours.
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Alcohol

Caution

It is unknown if alcohol interacts with Omnipaque 300 mg Injection. Please consult a doctor if you have any concerns.

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Pregnancy

Caution

Omnipaque 300 mg Injection should be used in pregnancy only if clearly needed. If you are pregnant, inform your doctor beforehand.

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Breast Feeding

Caution

There is limited data on the use of Omnipaque 300 mg Injection during breastfeeding. Consult your healthcare provider to assess risks and benefits.

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Driving

Caution

Omnipaque 300 mg Injection may affect vision temporarily. Avoid driving or operating heavy machinery if you experience visual disturbances after the injection.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Omnipaque 300 mg Injection. It should be used with caution in patients with severe liver impairment.

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Kidney

Caution

If you have a history of kidney disorder, inform your doctor before receiving Omnipaque 300 mg Injection. It should be used with caution in patients with severe kidney impairment.

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Children

Caution

Your doctor will adjust the dosage of name for children based on age, weight, and the imaging procedure, ensuring it is used safely.

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Heart

Caution

Please inform your doctor if you have any history of heart disease, arrhythmia, or high blood pressure before starting the treatment, as Omnipaque 300 mg Injection may increase the risk of cardiovascular side effects.

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Geriatrics

Consult your doctor

Please take the advice of your doctor before giving Omnipaque 300 mg Injection to elderly people. Your doctor will prescribe Omnipaque 300 mg Injection if the benefits outweigh the risk.

What if I have taken an overdose of Omnipaque 300 mg Injection

An overdose is highly unlikely because this medicine is administered under close medical supervision by trained healthcare professionals. However, if you feel seriously unwell after leaving the hospital or clinic, seek immediate medical attention or go to the nearest emergency department without delay.

Diet & Lifestyle Advise

  • Drink plenty of water: Staying well hydrated before and after the procedure helps your kidneys remove the medicine from your body.
  • Follow fasting instructions carefully: Avoid solid food for the recommended period before your scan if your healthcare team instructs you to do so.
  • Rest after the procedure if needed: If you feel light-headed or dizzy after the scan, sit or lie down until you feel better.
  • Limit alcohol and caffeine for the next 24 hours: These drinks may contribute to dehydration, making it harder for your kidneys to eliminate the medicine efficiently.
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How Soon It Starts Working

The time required for Omnipaque 300 mg Injection to start to work: Omnipaque 300 mg Injection starts to show its action within a few minutes of administration. The time for which the effects of Omnipaque 300 mg Injection last: The duration of Omnipaque 300 mg Injection effect is unknown.

What if you forget to take Omnipaque 300 mg Injection

Because Omnipaque 300 mg Injection is given only once by a healthcare professional as part of a scheduled imaging procedure, missing a dose is uncommon. If your appointment is postponed or rescheduled, the injection will be given at your new appointment.

Storage

• Store the medicine at room temperature, preferably between 20°C and 25°C, or according to the storage instructions on the product label.

Drug Warnings

  • Check your kidney function: Your doctor may recommend kidney function tests before your scan, especially if you have kidney disease, diabetes, or are over 65 years of age.
  • The solution should be inspected before use: Healthcare professionals should ensure the injection is clear, colourless to pale yellow, and free from visible particles before administration.
  • Report injection-site discomfort immediately: Tell the healthcare team if you notice burning, stinging, pain, or swelling while the medicine is being injected.
  • Tell your doctor if you have thyroid disease: Because this medicine contains iodine, it may temporarily affect thyroid function.
  • Remain under observation after the procedure: You may be asked to stay at the clinic or hospital for about 30 minutes because most serious allergic reactions occur shortly after the injection.

Drug-Drug Interactions

verifiedApollotooltip
  • Metformin: Your doctor may advise temporarily stopping metformin around the time of the scan, particularly if you have reduced kidney function, to reduce the risk of lactic acidosis.
  • Medicines that affect the kidneys: Certain antibiotics, NSAID pain relievers such as ibuprofen, and other medicines that may affect kidney function can increase the risk of kidney problems when used with iodinated contrast agents.
IohexolBetamethasone
Critical
IohexolPrednisolone
Critical

Drug-Drug Interactions

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IohexolBetamethasone
Critical
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Co-administration of Omnipaque 300 mg Injection 50 ml and Betamethasone can increase the risk of seizures.

How to manage the interaction:
Taking Betamethasone with Omnipaque 300 mg Injection 50 ml is not recommended, please consult your doctor before taking it.
IohexolPrednisolone
Critical
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Co-administration of Omnipaque 300 mg Injection 50 ml and Prednisolone can increase the risk of side effects.

How to manage the interaction:
Taking Prednisolone with Omnipaque 300 mg Injection 50 ml is not generally advised as they can lead to an interaction, they can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
IohexolMetformin
Critical
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Co-administration of Omnipaque 300 mg Injection 50 ml with Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Metformin with Omnipaque 300 mg Injection 50 ml is generally avoided as it can result in an interaction, please consult your doctor before taking it.
IohexolMethylprednisolone
Critical
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Co-administration of Methylphenidate with Omnipaque 300 mg Injection 50 ml may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Methylprednisolone with Omnipaque 300 mg Injection 50 ml is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IohexolLidocaine
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Taking Omnipaque 300 mg Injection 50 ml and Lidocaine may increase the risk of causing seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Lidocaine and Omnipaque 300 mg Injection 50 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
IohexolNorfloxacin
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Coadministration of Norfloxacin with Omnipaque 300 mg Injection 50 ml may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Norfloxacin with Omnipaque 300 mg Injection 50 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not discontinue any medications without consulting a doctor.
IohexolVilazodone
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Co-administration of Omnipaque 300 mg Injection 50 ml with Vilazodone may increase the side effects of Vilazodone.

How to manage the interaction:
Taking Vilazodone with Omnipaque 300 mg Injection 50 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without a doctor's advice.
IohexolLevofloxacin
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Coadministration of Levofloxacin and Omnipaque 300 mg Injection 50 ml can cause seizures (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Co-administration of Levofloxacin with Omnipaque 300 mg Injection 50 ml can result in an interaction, but it can be taken if a doctor has advised it. If you need to use both medications at the same time, it's important to keep a close eye on your health. If you notice any of these signs - being closely monitored by your doctor, having seizures, or having a condition or head injury - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
IohexolAmantadine
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Coadministration of Amantadine with Omnipaque 300 mg Injection 50 ml may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Amantadine and Omnipaque 300 mg Injection 50 ml together can cause an interaction, it can be taken if your doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
IohexolVenlafaxine
Severe
How does the drug interact with Omnipaque 300 mg Injection 50 ml:
Omnipaque 300 mg Injection 50 ml can cause seizures and taking it with venlafaxine may increase that risk.

How to manage the interaction:
Although taking Venlafaxine and Omnipaque 300 mg Injection 50 ml together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Omnipaque 300 mg Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Omnipaque 300 mg Injection is a contrast agent used in diagnostic imaging procedures such as X-rays, CT scans, and angiography. It helps enhance the visibility of blood vessels and internal organs, allowing for better imaging and accurate diagnosis of various conditions.
Omnipaque 300 mg Injection works by absorbing X-rays and enhancing the contrast in the images taken during diagnostic procedures. This helps doctors observe blood vessels, organs, and tissues with greater detail, enabling accurate diagnoses.
If you have kidney problems, consult your doctor before receiving Omnipaque 300 mg Injection, as it may increase the risk of kidney complications. Your doctor may adjust the dosage or option for an alternative contrast medium.
Omnipaque 300 mg Injection should only be received during pregnancy or breastfeeding if necessary. Consult your doctor if you are pregnant or breastfeeding before receiving it.
Common side effects may include diarrhea, nausea, vomiting, stomach pain, gas, back pain, sweating, or headache. Seek medical care if the symptoms persist or worsen.
Omnipaque 300 mg Injection is generally safe for most people, however, it should be used with caution in persons who are allergic to iodine, have kidney difficulties, or have had previous contrast reactions. Always counsel your doctor about any pre-existing conditions.
In people with normal kidney function, most of the medicine is removed from the body in the urine within about 24 hours. Drinking plenty of water after the procedure helps your kidneys eliminate it more efficiently.
Yes. A temporary feeling of warmth or flushing is one of the most common effects of this medicine. It usually lasts only a minute or two and settles on its own.
Most people can drive home if they feel well after the procedure. However, if you feel dizzy, light-headed, or unwell, wait until you have fully recovered before driving or arrange for someone else to take you home.
Only an extremely small amount of this medicine passes into breast milk, and very little is absorbed by a breastfed baby. Most medical guidelines do not recommend stopping breastfeeding after receiving iohexol. If you have concerns, discuss them with your doctor before the procedure.
Yes, it may still be used when necessary, but your doctor will assess your kidney function carefully before the procedure. Extra precautions, such as ensuring you are well hydrated or adjusting your care plan, may be recommended.
Your preparation instructions depend on the type of imaging procedure you are having. You may be asked to avoid solid food for several hours before the scan while continuing to drink clear fluids, unless your healthcare team advises otherwise. Always follow the instructions provided by your hospital or imaging centre.
Yes. Although most people do not experience serious problems, allergic reactions can occur. Mild reactions such as itching or a rash are more common, while severe reactions are rare. Your healthcare team is prepared to recognise and treat these reactions promptly if they occur.
A temporary metallic taste is a common and harmless effect of iodinated contrast agents. It usually disappears within a few minutes after the injection has been completed.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - OMN0173

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