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compositionComposition:OMALIZUMAB-150MG
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Omalirel Injection is a monoclonal antibody used to treat allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic spontaneous urticaria. It works by targeting and neutralizing immunoglobulin E (IgE), a primary antibody responsible for initiating allergic reactions. Common side effects may include joint pain, dizziness, stomach discomfort, headaches, ear pain, and reactions at the injection site, such as pain, swelling, itching, and redness. It is not recommended for use in children under the age of 6.

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Written By ,
Reviewed By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
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More about the Product

Composition :

OMALIZUMAB-150MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Omalirel Injection

Omalirel Injection is an injection used to treat severe allergic asthma, long-lasting hives with no known cause, and chronic nasal polyps. It is prescribed when standard treatments do not fully control these symptoms. This medicine helps lower the frequency of severe flare-ups and eases persistent breathing or skin issues.

This medicine is typically injected every 2 or 4 weeks, and it must be taken consistently to remain effective over time. Along with taking this medicine, avoiding personal allergy triggers like dust mites, pet dander, or specific foods can help you achieve better results. Your doctor can help you identify these triggers and create a management plan.

While using Omalirel Injection, you may experience mild side effects like headache, joint pain, or mild swelling at the injection site. However, you must seek medical attention immediately if you notice serious symptoms such as swelling of the throat, severe dizziness, or trouble breathing. It is important to monitor how you feel after each injection.

Do not take this if you have had a severe allergic reaction to this medicine or any of its ingredients in the past. Talk to your doctor before starting this medicine if you have a history of cancer, severe allergies, or parasitic infections. This medicine may not be suitable for everyone, so a thorough medical review is necessary.

Let your doctor know about all other medicines you take, as certain vaccines or immune therapies may interact with Omalirel Injection. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to understand the safety of using this medicine. They will help you weigh the benefits and potential risks.

Uses of Omalirel Injection

Uses of Omalirel Injection may include:

  • Severe Allergic Asthma: Helps manage severe, persistent asthma in adults and children when inhaled steroid medicines do not work well enough.
  • Chronic Spontaneous Urticaria (Chronic Hives): Treats long-lasting hives and skin swelling that do not respond to antihistamine medications.
  • Nasal Polyps: Helps shrink growths in the nasal passages to improve breathing and reduce nasal congestion when other treatments fail.

Key Benefits

Omalirel Injection is a biologic medicine used to manage certain allergic conditions, including allergic asthma, chronic spontaneous urticaria, and nasal polyps. It works by targeting immunoglobulin E (IgE), an important mediator of allergic inflammation.

  • Helps Control Allergic Asthma: Reduces allergic inflammation and may decrease the frequency of asthma exacerbations in people with appropriately diagnosed severe allergic asthma.
  • Reduces Chronic Hives: Helps reduce the number and severity of hives and may relieve associated itching in people with chronic spontaneous urticaria.
  • Helps Manage Nasal Polyps: May reduce nasal congestion and the size of nasal polyps, helping improve breathing and other associated symptoms.
  • Reduces the Need for Rescue Treatment: Better control of allergic inflammation may reduce asthma exacerbations and the need for additional rescue treatments in appropriate patients.
  • Improves Daily Comfort: Better control of asthma, hives, or nasal symptoms may improve sleep, daily functioning, and overall quality of life.
Side effects of Omalirel Injection
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Hold the syringe straight and inject it under the skin, typically in the thigh, abdomen, or upper arm.
  • Before administration, ensure that the injection site is clean. Rotate injection sites to reduce discomfort or irritation. Use Omalirel Injection only after receiving proper training from the healthcare professional.

How Omalirel Injection Works

Omalirel Injection contains omalizumab. It works by targeting a specific antibody in your body called immunoglobulin E (IgE). IgE is a natural substance that your immune system produces in response to allergens like pollen, dust, or certain foods. In people with allergic asthma or chronic hives, the body produces too much IgE, which triggers the release of inflammatory chemicals that cause swelling, airway tightening, and skin irritation. When you inject Omalirel Injection, it binds to the IgE circulating in your blood. This action blocks IgE from attaching to inflammatory cells, reducing the release of chemicals that cause allergic symptoms. By stopping this chain reaction early, the medicine helps control airway inflammation and skin symptoms.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Omalirel Injection. Alcohol intake, along with Omalirel Injection, may cause increased dizziness.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Omalirel Injection. Your doctor may recommend this medication if the potential benefits outweigh the potential risks.

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Breast Feeding

Consult your doctor

Omalirel Injection may pass into breast milk. If you are breast-feeding or plan to breast-feed, please consult your doctor before using it.

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Driving

Caution

Omalirel Injection may make you feel dizzy. Avoid driving or operating machinery until you are fully alert and aware.

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Liver

Consult your doctor

Please inform your doctor if you have liver impairment/liver disease before receiving Omalirel Injection.

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Kidney

Consult your doctor

Please inform your doctor if you have kidney impairment/kidney disease before receiving Omalirel Injection.

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Children

Caution

Omalirel Injection is not recommended in children below 6 years of age as the safety and efficacy are not established.

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Heart

Safe if prescribed

Omalirel Injection can generally be taken even if you have heart problems. Consult your doctor if you have any concerns regarding it.

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Geriatrics

Safe if prescribed

Geriatric patients can receive Omalirel Injection, but with careful consideration and monitoring.

What if I have taken an overdose of Omalirel Injection

If you suspect you have received or injected too much of this medicine, seek immediate medical attention or contact a poison control centre.

Diet & Lifestyle Advise

  • Identify and Avoid Triggers: Minimise exposure to personal asthma and allergy triggers, such as tobacco smoke, dust mites, pollen, mould, and pet dander.
  • Keep a Symptom Diary: Record asthma symptoms, hive flare-ups, nasal symptoms, and the dates of your injections to help your doctor assess how well your treatment is working.
  • Wear Comfortable Clothing: Choose loose-fitting, breathable clothing to reduce friction and skin irritation if you experience chronic hives.
  • Avoid Excessive Heat: Avoid very hot baths and showers, as heat may worsen itching or trigger hives in some people.
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Have a query?

How Soon It Starts Working

The time required for Omalirel Injection to start to work: The exact onset time of Omalirel Injection has not been clinically established. The time for which the effects of Omalirel Injection last: The duration of Omalirel Injection’s effect is clinically not established.

What if you forget to take Omalirel Injection

If you miss an injection, call your healthcare provider right away to reschedule. Do not inject a double dose to make up for a missed one.

Storage

•Store Omalirel Injection in the refrigerator between 2°C and 8°C.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the Medicine Before Use: Check the syringe or vial before administration. Do not use it if the solution appears cloudy, discoloured, or contains unexpected visible particles.
  • Rotate Injection Sites: Change the injection site with each dose to reduce the risk of soreness, bruising, or skin changes at the injection site.
  • Watch for Severe Allergic Reactions: Omalizumab can rarely cause anaphylaxis, which may occur shortly after an injection or, in some cases, later. Seek immediate medical attention if you develop difficulty breathing, throat or tongue swelling, severe dizziness, or widespread hives after receiving the medicine.
  • Do Not Stop Other Asthma Medicines Suddenly: Continue your other asthma or allergy medicines as prescribed. Do not reduce or stop corticosteroids or other controller medicines unless your doctor tells you to do so.
  • Avoid Irritated Injection Sites: Do not inject into areas that are painful, red, bruised, hard, or scarred. Follow the injection-site instructions provided by your healthcare professional.

Drug-Drug Interactions

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Inform your doctor about all medicines you are taking, as Omalirel Injection may interact with certain treatments:

  • Medicines for parasitic infections: Omalirel Injection may reduce the effectiveness of medicines used to treat hookworm, roundworm, or other parasite infections. Let your doctor know if you are being treated for a parasite.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Omalirel Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MONOCLONAL ANTIBODIES]

FAQs

Omalirel Injection is a monoclonal antibody used to treat allergic asthma, chronic rhinosinusitis (inflammation of the nose and sinuses) with nasal polyps and chronic spontaneous urticaria.
Omalirel Injection contains Omalizumab, as an active ingredient which belongs to the class of monoclonal antibodies. It works by targeting and neutralizing immunoglobulin E (IgE), a key antibody responsible for triggering allergic reactions.
Do not discontinue treatment with Omalirel Injection without consulting your doctor. To treat your medical condition effectively, continue using Omalirel Injection or visit your doctor for administration as long as it has been prescribed for you.
Please inform your doctor before taking other medicines while being treated with Omalirel Injection. Your doctor will determine which medicines should not be taken along with Omalirel Injection.
Omalirel Injection may cause common side effects, such as joint pain, dizziness, upper abdominal pain, common cold, headache, ear pain and injection site reactions including pain, swelling, itching and redness. Please consult your doctor if any of these side effects persist or worsen.
Seek emergency medical help immediately if you develop hives, swelling of your face or throat, or trouble breathing, even if it occurs days after your injection. Talk to your doctor about how to recognise these symptoms.
No, you must not stop or change the dose of your other asthma medicines unless your doctor specifically instructs you to. Omalirel Injection is designed to work alongside your current treatments, not replace them.
There is limited information on the safety of this medicine during pregnancy or breastfeeding. Talk to your doctor to weigh the benefits and potential risks before starting or continuing treatment.
This medicine specifically targets IgE, which is involved in allergic reactions, so it does not generally weaken your entire immune system. However, it may make it slightly harder for your body to fight certain parasite infections. Talk to your doctor if you have concerns.
If you miss a scheduled dose, contact your healthcare provider's office right away to reschedule your injection. Do not inject a double dose to make up for the missed one.
There is no direct chemical interaction between alcohol and Omalirel Injection. However, alcohol can be a trigger for asthma symptoms or hives in some individuals, so talk to your doctor or pharmacist for personalised advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Other Info - OMA0031
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