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  1. Home
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  3. Olapin Plus Tablet 10's

Olapin Plus Tablet 10's, Pack of 10 TABLETS
Olapin Plus Tablet 10's, Pack of 10 TABLETS
Olapin Plus Tablet 10's, Pack of 10 TABLETS
Olapin Plus Tablet 10's, Pack of 10 TABLETS
Olapin Plus Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Olapin Plus Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Fluoxetine and Olanzapine which work by restoring the balance of certain natural substances in the brain. In some cases, this medicine may cause side effects such as drowsiness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, and increased appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

FLUOXETINE-20MG + OLANZAPINE-5MG

Manufacturer/Marketer :

Crescent Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Olapin Plus Tablet

Olapin Plus Tablet belongs to the class of antipsychotics used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by symptoms of hallucinations (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Olapin Plus Tablet prevents the occurrence of these symptoms. 

Olapin Plus Tablet consists of two medicines, namely: Fluoxetine and Olanzapine. Olapin Plus Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Olapin Plus Tablet is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether Olapin Plus Tablet may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

You are suggested to take $ame for as long as your doctor has prescribed it. Common side-effects of Olapin Plus Tablet are drowsiness, lightheadedness, restlessness, irritability, tremor, dry mouth, constipation, increased appetite, extreme fatigue, decreased libido, swelling of the hands or feet, or weight gain. Inform your doctor if any of these side effects persist or worsen.

Do not take Olapin Plus Tablet if you are allergic (hypersensitive) to any of the ingredients present in this medicine. Inform your doctor if you have a medical history of dementia, glaucoma (increased pressure in the eye), stroke, heart diseases, diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy (seizures), prostate problems, a blocked intestine (Paralytic ileus), and blood disorders. Olapin Plus Tablet may increase blood glucose levels, so inform your doctor immediately if you have symptoms such as increased thirst or urination. It may also cause weight gain and increase fat levels in the body.

Uses of Olapin Plus Tablet

Treatment of Schizophrenia (mental illness), bipolar disorder (manic depression).

Directions for Use

• Take Olapin Plus Tablet with or without food as advised by your doctor.• It is advised to take Olapin Plus Tablet once daily; however, follow your doctor’s recommendation regarding the dosage and duration.• Swallow it as a whole with a glass of water.• Do not crush, chew or break it.

Medicinal Benefits

Olapin Plus Tablet is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Olapin Plus Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Olapin Plus Tablet is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether Olapin Plus Tablet may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

How Olapin Plus Tablet Works

Olapin Plus Tablet consists of two medicines, namely: Fluoxetine and Olanzapine. Olapin Plus Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Olapin Plus Tablet is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether Olapin Plus Tablet may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

Storage

Keep Olapin Plus Tablet out of the sight and reach of children.
Side effects of Olapin Plus Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Write things in a notebook or on sticky notes.
  • Be physically and mentally active.
  • Maintain social interaction to avoid stress and depression which could contribute to memory loss.
  • Sleep well as inadequate sleep may also cause memory loss.
  • Maintain a healthy diet which includes fruits, vegetables, whole grains, fish and skinless poultry.
  • Avoid alcohol consumption as it may cause confusion and memory loss.

What if I have taken an overdose of Olapin Plus Tablet

Take Olapin Plus Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include fast/irregular heartbeat, severe dizziness, seizures, and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Olapin Plus Tablet if you are allergic (hypersensitive) to any of the ingredients present in this medicine or have a medical history of eye problems such as glaucoma (increased pressure in the eye). Before taking Olapin Plus Tablet , talk to your doctor if you or your family have a history of blood clots, stroke, or heart diseases and if you are above 65 years and have a history of dementia (memory loss). Olapin Plus Tablet may cause weight gain and increase blood glucose and cholesterol levels. Inform your doctor if you are previously diagnosed with diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy, prostate problems, a blocked intestine (Paralytic ileus) or blood disorders.

Drug-Drug Interactions

verifiedApollotooltip
OlanzapinePotassium citrate
Critical
OlanzapineRopinirole
Critical

Drug-Drug Interactions

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OlanzapinePotassium citrate
Critical
How does the drug interact with Olapin Plus Tablet:
Taking Olapin Plus Tablet with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Olapin Plus Tablet and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineRopinirole
Critical
How does the drug interact with Olapin Plus Tablet:
When Ropinirole is taken with Olapin Plus Tablet, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Olapin Plus Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
OlanzapinePramipexole
Critical
How does the drug interact with Olapin Plus Tablet:
Taking Olapin Plus Tablet with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Olapin Plus Tablet and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapinePotassium chloride
Critical
How does the drug interact with Olapin Plus Tablet:
Taking Olapin Plus Tablet with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Olapin Plus Tablet and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineBupropion
Severe
How does the drug interact with Olapin Plus Tablet:
Combining of Olapin Plus Tablet and Bupropion can increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Olapin Plus Tablet can lead to an interaction, but it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
OlanzapineCiprofloxacin
Severe
How does the drug interact with Olapin Plus Tablet:
Coadministration of Olapin Plus Tablet and ciprofloxacin can increase blood levels and the effects of Olapin Plus Tablet, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Olapin Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience difficulty swallowing, low blood pressure, irregular heart rhythm, and seizures(fits) consult the doctor immediately. Do not stop using any medications without talking to a doctor.
OlanzapineFentanyl
Severe
How does the drug interact with Olapin Plus Tablet:
Taking Olapin Plus Tablet with fentanyl can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Olapin Plus Tablet and fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sleepiness, difficulty concentrating, and impaired judgment. Do not discontinue any medications without consulting a doctor.
OlanzapineTetrabenazine
Severe
How does the drug interact with Olapin Plus Tablet:
Co-administration of Tetrabenazine and Olapin Plus Tablet can increase the risk of an irregular heart rhythm and the severity of side effects associated with Olapin Plus Tablet.

How to manage the interaction:
Co-administration of Tetrabenazine and Olapin Plus Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, fever, heat intolerance, excessive sweating, stiffness, difficulty moving or swallowing, sudden dizziness, lightheadedness, fainting, and fast or pounding heartbeats, contact your doctor immediately. Avoid activities requiring mental alertness, such as driving or operating machinery, until you know how these medications affect you and do not discontinue any medications without consulting your doctor.
OlanzapineIohexol
Severe
How does the drug interact with Olapin Plus Tablet:
The combined use of Iohexol and Olapin Plus Tablet can increase the risk of seizures as Iohexol be injected directly into the spine.

How to manage the interaction:
Taking Olapin Plus Tablet with Iohexol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
OlanzapineHydromorphone
Severe
How does the drug interact with Olapin Plus Tablet:
Combining Olapin Plus Tablet with Hydromorphone can cause central nervous system depression such as Olapin Plus Tablet can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Olapin Plus Tablet and Hydromorphone together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine, and activities that can impact your mood. 

  • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.

  • You may also practice calming techniques such as meditation and deep breathing exercises.

  • Sleep well. Having enough sleep will help to stabilize your mood.

  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.

  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Olapin Plus Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Patients taking Olapin Plus Tablet should avoid taking alcohol as it may increase drowsiness.

bannner image

Pregnancy

Caution

Olapin Plus Tablet should be used in pregnant women only when prescribed by a doctor.

bannner image

Breast Feeding

Unsafe

Olapin Plus Tablet should not be given to breastfeeding mothers.

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Driving

Unsafe

Olapin Plus Tablet causes drowsiness. So, avoid driving or operating heavy machinery after taking Olapin Plus Tablet .

bannner image

Liver

Caution

Olapin Plus Tablet should be used with caution in patients with liver diseases.

bannner image

Kidney

Caution

Olapin Plus Tablet should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.

bannner image

Children

Unsafe

Olapin Plus Tablet should not be prescribed in children below 12 years of age.

Have a query?

FAQs

Olapin Plus Tablet is used to treat schizophrenia (mental illness) and bipolar disorder (manic depression). It works by restoring the balance of certain natural substances in the brain.

Olapin Plus Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Olapin Plus Tablet for any condition.

Long-term use of Olapin Plus Tablet may cause dyskinesia (a movement disorder) in some cases. However, your doctor will prescribe this medication if the benefits outweigh the risks.

Olapin Plus Tablet can be used to treat mood disorders such as schizophrenia, bipolar disorder, anxiety, and depression. However, you should not take this medication without a doctor’s advice.

Olapin Plus Tablet may cause decreased libido in men and women. It can cause erectile dysfunction in men as it can alter testosterone levels. Consult a doctor if you experience erectile dysfunction after taking Olapin Plus Tablet .

Stopping Olapin Plus Tablet abruptly can cause withdrawal symptoms, and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Olapin Plus Tablet .

Olapin Plus Tablet may cause severe side effects, such as memory loss and loss of contact with reality. It is important to know that it may raise blood sugar levels in diabetics and in patients who have never had diabetes. It can also induce weight gain and high blood fat levels which are more common in adolescents.

No, Olapin Plus Tablet is not a sleeping pill. It is an antipsychotic medication used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression).

Olapin Plus Tablet should be used by pregnant women only when prescribed by a doctor. Please consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

Do not discontinue Olapin Plus Tablet without consulting your doctor as stopping Olapin Plus Tablet suddenly may cause withdrawal symptoms. To treat your condition effectively, keep taking Olapin Plus Tablet for the prescribed duration.

Avoid smoking as it might interfere with the working of Olapin Plus Tablet . Do not consume alcohol while on treatment with Olapin Plus Tablet as it may cause increased drowsiness.

Common side-effects of Olapin Plus Tablet are drowsiness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, increased appetite, extreme fatigue, decreased libido, swelling of the hands or feet, or weight gain. Inform your doctor if any of these side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - OLA0016

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:50 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.3071.pdf
  2. https://www.drugs.com/mtm/olanzapine.html
  3. https://www.webmd.com/drugs/2/drug-1644-9274/olanzapine-oral/olanzapine-oral/details

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