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Odirab-D Capsule is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, the fullness of stomach, bloating, gas, helicobacter pylori infection, gastric and duodenal ulcers. It contains Rabeprazole sodium and Domperidone, which blocks acid production and increases the movements and contractions of the stomach muscle. Thus, helps in treating acidity-related problems. It may cause common side effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Odirab-D Capsule

Odirab-D Capsule is a prescription medicine used to treat symptoms of gastro-oesophageal reflux disease (GERD), acid reflux, and stomach ulcers. It helps relieve troublesome symptoms such as heartburn, acid backflow, and the discomfort of an upset stomach. By lowering acid levels and helping food move more smoothly through your digestive system, it provides comprehensive relief for upper digestive issues.

To get the best results, you should take Odirab-D Capsule consistently as prescribed by your doctor, typically in the morning. It is highly recommended to take this medicine on an empty stomach, at least 30 minutes before your meal, to ensure it absorbs properly. Making simple lifestyle adjustments, such as eating smaller meals and avoiding lying down right after eating, can also greatly improve your recovery.

While taking Odirab-D Capsule , some people may experience mild side effects, including headaches, dry mouth, or mild stomach pain. These symptoms are generally temporary and tend to improve as your body gets used to the medication. However, if you develop any severe or persistent symptoms, such as an irregular heartbeat, muscle weakness, or severe diarrhoea, you should contact your doctor immediately.

Before you begin taking Odirab-D Capsule , talk to your doctor if you have a history of liver damage, kidney issues, or heart disease. Do not take this if you have a known blockage in your stomach or intestines, stomach bleeding, or a tumour of the pituitary gland. It is also not suitable for individuals with certain pre-existing heart rhythm conditions.

Certain medicines, including blood thinners and some antifungal drugs, can interact with Odirab-D Capsule because they alter how your body processes these active substances. Smoking and drinking alcohol can also irritate your stomach and make this treatment less effective. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to make sure this medicine is safe for you.

Uses of Odirab-D Capsule

Odirab-D Capsule is a combination medicine used to reduce stomach acid production and improve stomach emptying. It is commonly prescribed for the following conditions:

  • Gastroesophageal Reflux Disease (GERD): Odirab-D Capsule helps by reducing the amount of acid your stomach produces and preventing it from flowing back up into your food pipe, which relieves heartburn and prevents damage to the oesophagus.
  • Peptic Ulcer Disease: It aids in the healing of painful sores in the stomach or upper small intestine by keeping stomach acid low enough for the tissues to recover.
  • Acid-Related Dyspepsia: It relieves symptoms of indigestion, bloating, and early fullness after eating by speeding up how quickly food moves through your stomach.
  • Nausea Associated with Reflux: It directly targets the signals in the brain and gut that cause feelings of sickness, helping to control nausea and prevent vomiting.

Key Benefits

Odirab-D Capsule provides dual-action relief by reducing excess stomach acid while improving stomach motility. The following benefits help improve digestive comfort and support the healing process:

  • Provides Effective Relief from Heartburn and Acid Reflux: By reducing stomach acid production, it relieves heartburn, acid regurgitation, and burning discomfort associated with GERD.
  • Relieves Nausea and Improves Stomach Emptying: The domperidone component helps food move more efficiently through the stomach, reducing nausea, vomiting, bloating, and the feeling of fullness after meals.
  • Promotes Healing of the Digestive Tract: Lower stomach acid levels allow ulcers and inflammation in the stomach and oesophagus to heal more effectively, reducing the risk of complications.
  • Improves Digestive Comfort: It helps relieve indigestion, upper abdominal discomfort, and post-meal bloating, making eating more comfortable.
  • Supports Better Daily Comfort and Sleep: By controlling acid reflux symptoms throughout the day and night, Odirab-D Capsule helps reduce interruptions to meals, daily activities, and restful sleep.
Side effects of Odirab-D Capsule
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Recommended to take Odirab-D Capsule 30 minutes before a meal or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Odirab-D Capsule Works

Odirab-D Capsule contains two active medicines that work together to reduce stomach acid and improve the movement of food through the digestive tract, helping relieve acid reflux, heartburn, and indigestion. Rabeprazole sodium is a proton pump inhibitor (PPI). It works by blocking the acid-producing pumps in the lining of the stomach, significantly reducing the amount of acid released. This helps relieve heartburn, allows the stomach and food pipe to heal, and prevents further damage caused by excess stomach acid. Domperidone is a prokinetic medicine and dopamine (D2) receptor antagonist. It works by blocking dopamine receptors that slow stomach emptying, increasing the movement and contractions of the stomach and upper intestine so food passes more quickly through the digestive system. It also helps reduce nausea and vomiting by blocking dopamine receptors involved in the vomiting reflex. This reduces the likelihood of stomach contents flowing back into the food pipe and helps relieve symptoms such as nausea, vomiting, bloating, and a feeling of fullness. Together, these medicines help relieve acid reflux, heartburn, indigestion, nausea, and bloating while promoting healing of the digestive tract.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Odirab-D Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

If you are pregnant consult your doctor before taking Odirab-D Capsule ; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, consult your doctor before taking Odirab-D Capsule ; your doctor will decide whether Odirab-D Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Odirab-D Capsule may cause dizziness. Hence, do not drive or operate machinery unless you are alert after taking this medicine.

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Liver

Caution

Odirab-D Capsule is contraindicated in patients with moderate to severe liver disease. If you have pre-existing liver problems, consult your doctor before taking this medicine. Your doctor may adjust the dose or may prescribe a suitable alternative based on your condition.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Odirab-D Capsule if you have kidney impairment or any concerns regarding this.

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Children

Caution

Odirab-D Capsule is not recommended for children as safety and effectiveness were not established.

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Heart

Caution

Odirab-D Capsule should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Safe if prescribed

Odirab-D Capsule is safe for use in geriatric patients if prescribed by the physician.

What if I have taken an overdose of Odirab-D Capsule

If you suspect an overdose, seek immediate medical attention or call a local poison control centre. Symptoms of an overdose may include severe dizziness, confusion, agitation, or an unusually fast or irregular heartbeat

Diet & Lifestyle Advise

  • Eat Smaller, More Frequent Meals: Eat smaller, more frequent meals throughout the day instead of three large meals to avoid putting too much pressure on your stomach.
  • Avoid Lying Down After Meals: Avoid lying down for at least 2 to 3 hours after eating to prevent stomach acid from flowing back into your throat.
  • Limit Foods That Trigger Reflux: Identify and limit food triggers that can worsen acid reflux, such as spicy, fatty, or fried foods, caffeine, chocolate, citrus fruits, and tomatoes.
  • Elevate the Head of Your Bed: Elevate the head of your bed by 6 to 9 inches using blocks or a wedge pillow to help gravity keep acid in your stomach while you sleep.
  • Avoid Tight-Fitting Clothing: Avoid wearing tight clothing around your waist, as this can squeeze your stomach and force acid upward.
  • Quit Smoking: Quitting smoking can significantly improve your symptoms, as nicotine weakens the muscle that keeps acid from entering the oesophagus.
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How Soon It Starts Working

The time required for Odirab-D Capsule to start to work: Odirab-D Capsule ideally shows its action within 1 hour after administration. The time for which the effects of Odirab-D Capsule last: The duration of action for Odirab-D Capsule is unknown.

What if you forget to take Odirab-D Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Odirab-D Capsule at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Inspect the Medicine Before Use: Always inspect the package and blister pack before use; do not take the medicine if the packaging is damaged or if the capsules appear cracked or discoloured.
  • Long-Term Use Requires Monitoring: If you need to use Odirab-D Capsule for a long time (more than three months), your doctor may need to monitor your magnesium levels through regular blood tests.
  • Be Aware of Bone Health: Long-term use of acid-reducing medicines can sometimes increase the risk of bone fractures, especially in older adults; talk to your doctor about calcium and vitamin D supplements.
  • Take Care When Driving or Operating Machinery: Avoid driving or operating heavy machinery until you know how Odirab-D Capsule affects you, as it can occasionally cause sleepiness or dizziness.
  • Inform Your Healthcare Provider About Other Medicines: Keep a complete list of all medications, supplements, and herbal products you take and share it with your doctor or pharmacist before starting Odirab-D Capsule .
  • Seek Immediate Medical Attention for Serious Symptoms: Seek medical help immediately if you develop a high fever, severe skin peeling, or joint pain, as these can be signs of rare but serious reactions.
  • Use for the Shortest Duration Necessary: Domperidone should be used at the lowest effective dose for the shortest duration recommended by your doctor, as prolonged use or higher doses may increase the risk of serious heart rhythm problems, particularly in older adults and people with underlying heart disease. 

Drug-Drug Interactions

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Odirab-D Capsule may interact with certain medicines, affecting how well they work or increasing the risk of side effects. Inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking, including:

  • Warfarin and Other Vitamin K Antagonists: Rabeprazole may affect blood clotting control (INR) in some people taking warfarin. Your doctor may monitor your INR more closely when starting or stopping this medicine.
  • Certain Antifungal or HIV Medicines: Rabeprazole can reduce the absorption of medicines that require stomach acid for proper absorption, making them less effective.
  • Medicines That Affect Heart Rhythm: Taking Odirab-D Capsule with medicines such as erythromycin, clarithromycin, amiodarone, or other QT-prolonging drugs may increase the risk of serious heart rhythm disturbances.
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Odirab-D Capsule:
Co-administration of Rilpivirine with Odirab-D Capsule can reduce the levels and effectiveness of Rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Odirab-D Capsule is generally avoided, it can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Odirab-D Capsule:
Coadministration of Citalopram with Odirab-D Capsule can reduce the levels and effectiveness of Erlotinib

How to manage the interaction:
Taking Citalopram with Odirab-D Capsule is generally avoided as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with Odirab-D Capsule:
Taking Dasatinib with Odirab-D Capsule can reduce the levels and effectiveness of Dasatinib.

How to manage the interaction:
Although Dasatinib with Odirab-D Capsule can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Odirab-D Capsule:
When Rabeprazole and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Rabeprazole.

How to manage the interaction:
Although taking Rabeprazole and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Odirab-D Capsule:
Taking Gefitinib with Odirab-D Capsule can reduce the levels and effectiveness of Gefitinib.

How to manage the interaction:
Although Gefitinib with Odirab-D Capsule can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Odirab-D Capsule:
Coadministration of Citalopram with Odirab-D Capsule can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although Citalopram with Odirab-D Capsule can lead to an interaction, it can be taken if your doctor has adviced it. If you experience lightheadedness, shortness of breath, or palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Odirab-D Capsule:
Co-administration of Domperidone with Nefazodone can increase the blood levels of Domperidone.

How to manage the interaction:
There may be a possibility of interaction between Domperidone and Nefazodone, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Odirab-D Capsule:
Taking Rabeprazole together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Rabeprazole and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Odirab-D Capsule:
Co-administration of Dacomitinib with Odirab-D Capsule may reduce the levels and effectiveness of Dacomitinib.

How to manage the interaction:
Taking Dacomitinib with Odirab-D Capsule can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Odirab-D Capsule:
Coadministration of Cisapride with Odirab-D Capsule can increase the levels of Odirab-D Capsule. This can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Cisapride with Odirab-D Capsule can result in an interaction, it can be taken if prescribed by a doctor. Contact a doctor if you experience shortness of breath, palpitations, or chest pain. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect the effectiveness of Odirab-D Capsule :

  • High-Fat Meals: Taking this medicine with high-fat meals can delay the absorption of the active ingredients, making it less effective at controlling acid when you need it.
  • Caffeine and Carbonated Beverages: Caffeine and carbonated beverages can stimulate acid production, directly counteracting the benefits of the medication.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Odirab-D Capsule is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, the fullness of stomach, bloating, gas, helicobacter pylori infection, gastric and duodenal ulcers.
Odirab-D Capsule contains Rabeprazole sodium and Domperidone. Rabeprazole sodium works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of the stomach muscle. Together, Odirab-D Capsule helps in treating acidity.
Diarrhoea might be a side-effect of Odirab-D Capsule . Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Odirab-D Capsule contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscle.
Do not take Odirab-D Capsule for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Odirab-D Capsule for 14 days.
It is best to take Odirab-D Capsule on an empty stomach, about 30 to 60 minutes before your first meal of the day. Taking it after food can delay how quickly the medicine starts to work. Talk to your doctor or pharmacist if you have questions about the timing of your dose.
Dry mouth is a common and usually mild side effect of this medicine. You can manage it by sipping water throughout the day, chewing sugar-free gum, or sucking on sugar-free hard candies. If the dry mouth becomes severe or bothersome, talk to your doctor.
Yes, some people may experience mild dizziness or sleepiness while taking Odirab-D Capsule . If you feel dizzy, avoid driving, operating machinery, or performing tasks that require full alertness until the feeling passes. Talk to your doctor if the dizziness is severe or does not go away.
You should generally avoid taking antacids at the exact same time as Odirab-D Capsule , as they can interfere with how well the medicine is absorbed. If you need to take an antacid for immediate relief, wait at least two hours after taking Odirab-D Capsule . Talk to your doctor before combining these treatments.
Odirab-D Capsule is generally not recommended for use during pregnancy unless your doctor decides that the benefits outweigh the potential risks to the baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this medication.
Yes, Odirab-D Capsule can interact with several types of medicines, including certain antifungals, blood thinners, and heart medications. Always provide your healthcare provider with a complete list of all prescription and over-the-counter medicines you are currently using. Talk to your doctor or pharmacist to make sure there are no harmful interactions.

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Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - ODI0101
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