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  3. Octotide 100mg Injection

Octotide 100mg Injection, Pack of 1 injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Octotide 100mg Injection is an antiemetic medication used in the treatment and prevention of nausea and vomiting during chemotherapy. This medication contains ondansetron which functions by inhibiting the activity of serotonin, a neurotransmitter that activates the brain's vomiting center (chemoreceptor trigger zone, or CTZ).

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Composition :

ONDANSETRON-100MG

Manufacturer/Marketer :

Euro Biotech

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Octotide 100mg Injection

Octotide 100mg Injection is used to prevent and treat nausea and vomiting during chemotherapy. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.

Octotide 100mg Injection contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

In some cases, Octotide 100mg Injection may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. If the side effects persist or worsen, please consult your doctor.

If you are allergic to Octotide 100mg Injection or any other medicines, please tell your doctor. It should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, you must inform your doctor before taking Octotide 100mg Injection.

Uses of Octotide 100mg Injection

Octotide 100mg Injection is used to prevent and treat nausea and vomiting caused by various medical conditions. The detailed uses of Octotide 100mg Injection are as follows:

  • Chemotherapy-induced nausea and vomiting (CINV) : Octotide 100mg Injection is used in adults and children to prevent and manage nausea and vomiting caused by cancer chemotherapy.
  • Post-operative nausea and vomiting (PONV): Octotide 100mg Injection helps prevent and treat nausea and vomiting that may occur after surgery.
  • Radiotherapy-induced nausea and vomiting: In adults receiving radiation treatment for cancer, Octotide 100mg Injection is used to reduce or prevent nausea and vomiting associated with therapy.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Octotide 100mg Injection will be administered by the doctor.
  • Do not self-administer.

Medicinal Benefits

  • Octotide 100mg Injection contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.
  • Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children, as well as after surgery.
  • Additionally, Octotide 100mg Injection can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

How Octotide 100mg Injection Works

Octotide 100mg Injection contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting center (chemoreceptor trigger zone CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Octotide 100mg Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Octotide 100mg Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.

What if I have taken an overdose of Octotide 100mg Injection

Octotide 100mg Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. There is no specific antidote for Ondansetron overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

  • If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor.
  • Octotide 100mg Injection should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area.
  • Octotide 100mg Injection should be used during pregnancy or breastfeeding after consultation with a doctor.
  • If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Octotide 100mg Injection.

Drug-Drug Interactions

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OctreotideTirzepatide
Moderate

Drug-Drug Interactions

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OctreotideTirzepatide
Moderate
How does the drug interact with Octotide 100mg Injection:
Blood glucose levels can occasionally be impacted by medications such as Octotide 100mg Injection. There have been reports of both high blood sugar and, less frequently, low blood sugar. During Octotide 100mg Injection medication, your blood glucose should be regularly checked so that your diabetic regimen can be modified as necessary.

How to manage the interaction:
During Octotide 100mg Injection medication, your blood glucose should be regularly checked so that your diabetic regimen can be modified as necessary.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Octotide 100mg Injection Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consuming alcohol while taking Octotide 100mg Injection as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before taking Octotide 100mg Injection. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

If you are a nursing mother, inform your doctor before taking Octotide 100mg Injection. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Caution

Octotide 100mg Injection usually does not affect your driving ability. However, do not drive if you feel any discomfort.

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Liver

Caution

Take Octotide 100mg Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Octotide 100mg Injection may be safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Consult your doctor

Octotide 100mg Injection should be used in children only in doses advised by the doctor based on child’s body weight or body surface area.

FAQs

Octotide 100mg Injection belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy.

Octotide 100mg Injection works by blocking the action of serotonin, a chemical that stimulates the vomiting center (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with Octotide 100mg Injection as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Octotide 100mg Injection.

Octotide 100mg Injection may cause constipation as a side effect. It is not necessary for everyone taking Octotide 100mg Injection to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

Octotide 100mg Injection should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking Octotide 100mg Injection so that the dose may be adjusted appropriately.

Yes, Octotide 100mg Injection may be used to prevent nausea and vomiting after surgery. Octotide 100mg Injection blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.

Country of origin

INDIA

Manufacturer/Marketer address

73, First Floor, Industrial Area Phase-2, Chandigarh - 160002, India
Other Info - OCT0049

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Sep 18, 2025 | 1:09 PM IST

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Reference

  1. https://www.hpra.ie/img/uploaded/swedocuments/5222449c-5347-4bed-8bf1-14edbf40c23d.pdf
  2. https://www.nps.org.au/assets/medicines/bb5dfa0a-c759-49c8-97ac-a53300ff3381.pdf
  3. https://extranet.who.int/pqweb/sites/default/files/documents/HA607part3v1.pdf

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