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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nuparp 200 Tablet is indicated in the treatment of ovarian, fallopian tube, and primary peritoneal cancer. It contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thus, it kills cancer cells and helps treat cancer. In some cases, it may cause side effects such as fatigue, nausea, vomiting, diarrhoea, and decreased or loss of appetite.

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Whats That

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Composition :

RUCAPARIB-200MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nuparp 200 Tablet

Nuparp 200 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of ovarian cancer, fallopian tube, and primary peritoneal cancer. It is also indicated in the treatment of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments.

Nuparp 200 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

In some cases, Nuparp 200 Tablet may cause side effects such as fatigue, nausea, vomiting, diarrhoea, decreased or loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, inform your doctor.

Let the doctor know if you are allergic to any of the components in Nuparp 200 Tablet . Nuparp 200 Tablet is not recommended for use in children as the safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Nuparp 200 Tablet

Nuparp 200 Tablet used in the treatment of ovarian cancer, fallopian tube cancer, primary peritoneal cancer and prostate cancer. The detailed uses of Nuparp 200 Tablet are as follows:<br/>• Treatment of Ovarian Cancer: Nuparp 200 Tablet targets and treats ovarian cancer, particularly in patients with BRCA mutations, by inhibiting PARP enzymes and blocking cancer cell growth.<br/>• Managing Fallopian Tube Cancer: Nuparp 200 Tablet provides treatment options for patients with fallopian tube cancer, offering a potential therapeutic benefit in managing the disease.<br/>• Therapy for Primary Peritoneal Cancer: Nuparp 200 Tablet is effective in treating primary peritoneal cancer, helping to control tumor growth and improve patient outcomes.<br/>• Treatment of Prostate Cancer: Nuparp 200 Tablet is used to treat certain cases of prostate cancer, especially those with specific genetic mutations, such as BRCA1 and BRCA2, providing a targeted treatment approach.<br/>

Directions for Use

• Nuparp 200 Tablet can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication. Try to take it at the same time each day or as recommended by a doctor for optimal results.• Swallow the whole tablet with a glass of water.• Do not break, chew or crush Nuparp 200 Tablet .

Medicinal Benefits

Nuparp 200 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of prostate cancer. It is also used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube, and primary peritoneal cancer that have returned in adults who have partially or completely responded to other chemotherapy treatments and in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Nuparp 200 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer. 

How Nuparp 200 Tablet Works

Nuparp 200 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nuparp 200 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nuparp 200 Tablet

Do not take more than prescribed dose. Using more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you may have overdosed of Nuparp 200 Tablet , please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Nuparp 200 Tablet if you are allergic to any of its components or if you are pregnant or breastfeeding. Nuparp 200 Tablet may cause serious side effects like bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Seek immediate medical attention if you experience weakness, weight loss, fever, frequent infections, blood in urine or stools, feeling very tired, shortness of breath, and bleeding or bruising more easily. Consult your doctor immediately if you become pregnant during treatment with Nuparp 200 Tablet . Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nuparp 200 Tablet:
Coadministration of Nuparp 200 Tablet and Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nuparp 200 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nuparp 200 Tablet:
When Nuparp 200 Tablet is taken with Infliximab, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Nuparp 200 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nuparp 200 Tablet:
Taking Nuparp 200 Tablet with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Nuparp 200 Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nuparp 200 Tablet:
Taking Pirfenidone with Nuparp 200 Tablet can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenidone with Nuparp 200 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
How does the drug interact with Nuparp 200 Tablet:
Using sotalol together with Nuparp 200 Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Nuparp 200 Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nuparp 200 Tablet:
Using moxifloxacin together with Nuparp 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Nuparp 200 Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - like a fast or irregular heartbeat, severe or long-lasting diarrhea, vomiting, complications, sudden feeling dizzy or lightheaded, fainting, difficulty breathing, or feeling your heart beating fast - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nuparp 200 Tablet:
Taking Gatifloxacin with Nuparp 200 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Nuparp 200 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain a proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
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Alcohol

Consult your doctor

It is not known whether Nuparp 200 Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Nuparp 200 Tablet should not be used during pregnancy as it may harm your unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Nuparp 200 Tablet and for at least two weeks after the last dose.

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Driving

Caution

In some cases, Nuparp 200 Tablet may cause tiredness. So, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, please inform your doctor before taking Nuparp 200 Tablet .

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Kidney

Consult your doctor

If you have a history of kidney disease, please inform your doctor before taking Nuparp 200 Tablet .

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Children

Unsafe

Nuparp 200 Tablet is not recommended for children as the safety and effectiveness have not been established.

Have a query?

FAQs

Nuparp 200 Tablet is used treat Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer and Prostate cancer.

Nuparp 200 Tablet works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it helps treat cancer.

Nuparp 200 Tablet may make your skin sensitive to sunlight. Therefore, avoid unnecessary or prolonged exposure to sunlight. Also, wear protective clothing and apply sunscreen.

If you experience nausea, vomiting, diarrhoea, or abdominal pain, consult your doctor, as these may be signs that Nuparp 200 Tablet is affecting your stomach or bowels.

Country of origin

INDIA

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - NUP0078

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