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compositionComposition:BEMPEDOIC ACID-180MG
prescription
Prescription Medicine
info
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Nudoic 180 Tablet is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BEMPEDOIC ACID-180MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nudoic 180 Tablet

Nudoic 180 Tablet is a tablet used to lower low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol, in the blood. It is prescribed for adults who need additional help lowering their cholesterol, particularly those with inherited high cholesterol or established heart disease. By lowering bad cholesterol, this medication helps reduce the risk of cardiovascular complications.

You should take Nudoic 180 Tablet consistently once every day, exactly as directed by your doctor. This oral tablet can be taken with or without food at any time of the day. To achieve the best results, it is important to continue with a heart-healthy diet and regular physical activity.

While taking Nudoic 180 Tablet , some people may experience mild side effects like muscle spasms, back pain, or pain in the arms or legs. However, you should consult your doctor immediately if you experience severe joint pain or signs of a tendon injury, as these can be serious.

Do not take this if you are pregnant, planning to become pregnant, or breastfeeding, as it may harm the unborn baby or infant. Before starting Nudoic 180 Tablet , talk to your doctor if you have ever had gout, severe kidney problems, or liver damage.

This medicine can interact with certain other cholesterol-lowering drugs, specifically high doses of simvastatin or pravastatin, which can increase the risk of muscle injury. Talk to your doctor or pharmacist about safe levels of alcohol, as both alcohol and this medicine can affect your liver. Elderly patients and those taking other prescription drugs should seek specific guidance to ensure safe use.

Uses of Nudoic 180 Tablet

Your doctor may prescribe Nudoic 180 Tablet to treat the following conditions to help lower cholesterol levels, reduce the risk of cardiovascular complications, and improve heart health:

  • High cholesterol (Hypercholesterolemia): Nudoic 180 Tablet helps lower high levels of low-density lipoprotein (LDL-C) in the blood when diet and maximum-dose statin therapy are not enough.
  • Heterozygous familial hypercholesterolemia (HeFH): This is an inherited condition that causes dangerously high cholesterol levels; Nudoic 180 Tablet helps by further reducing bad cholesterol in these individuals.
  • Atherosclerotic cardiovascular disease (ASCVD): For patients with established heart or blood vessel disease, Nudoic 180 Tablet helps lower cholesterol to target levels to prevent further cardiovascular events.

Key Benefits

Using Nudoic 180 Tablet as prescribed helps lower LDL (bad) cholesterol, support heart health, and reduce the risk of cardiovascular complications. Here are the key benefits you can expect:

  • Effectively lowers LDL cholesterol: Helps reduce high LDL (bad) cholesterol levels, especially when diet, lifestyle changes, and statin therapy alone are not enough.
  • Supports cardiovascular health: By lowering cholesterol production in the liver, it helps reduce the risk of future heart attacks, strokes, and other cardiovascular events.
  • Provides a convenient treatment option: Offers a once-daily oral tablet that can be used as an alternative or add-on treatment for people who cannot tolerate high doses of other cholesterol-lowering medicines due to muscle-related side effects.
Side effects of Nudoic 180 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.

Directions for Use

  • Nudoic 180 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication for effective results.
  • Swallow Nudoic 180 Tablet as a whole with water.
  • Do not crush, chew, or break it.

How Nudoic 180 Tablet Works

Nudoic 180 Tablet contains bempedoic acid, a cholesterol-lowering medicine that works by blocking an enzyme in the liver called adenosine triphosphate-citrate lyase (ACL). This enzyme plays an important role in the body's cholesterol production process. By blocking ACL, Nudoic 180 Tablet reduces the amount of cholesterol produced by the liver. In response, the liver removes more low-density lipoprotein (LDL), also known as 'bad' cholesterol, from the bloodstream. This helps lower LDL cholesterol levels and supports better cardiovascular health.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Nudoic 180 Tablet . Please consult a doctor.

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Pregnancy

Unsafe

Nudoic 180 Tablet may harm the unborn baby. Do not take Nudoic 180 Tablet if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Nudoic 180 Tablet .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Nudoic 180 Tablet if you are breastfeeding.

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Driving

Safe if prescribed

Nudoic 180 Tablet has little or no influence on your ability to drive.

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Liver

Consult your doctor

It is not known if Nudoic 180 Tablet is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

It is not known if Nudoic 180 Tablet is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nudoic 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Caution

Take Nudoic 180 Tablet with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Nudoic 180 Tablet if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Nudoic 180 Tablet can be used in the elderly when prescribed by a doctor. If you have any concerns about using Nudoic 180 Tablet , please consult a doctor.

What if I have taken an overdose of Nudoic 180 Tablet

If you accidentally take too much of this medicine, seek immediate medical attention. Bring the medication package with you so the healthcare providers know exactly what you took.

Diet & Lifestyle Advise

  • Follow a heart-healthy diet: Eat foods rich in soluble fibre, such as oats, beans, lentils, and fresh fruits, to help lower cholesterol absorption.
  • Limit unhealthy fats: Reduce your intake of saturated fats and avoid trans fats found in fried and processed foods, as they can increase LDL ('bad') cholesterol levels.
  • Maintain a healthy lifestyle: Aim for at least 150 minutes of moderate-intensity aerobic exercise, such as brisk walking or cycling, each week to support healthy cholesterol levels.
  • Stay well hydrated: Drink enough water throughout the day to support your overall health. (Maintaining hydration is beneficial, although it is not specifically related to the cholesterol-lowering effects of Nudoic 180 Tablet .)
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How Soon It Starts Working

  • The time required for Nudoic 180 Tablet to start to work: Nudoic 180 Tablet ideally shows its action within 3.5 hours after administration.
  • The time for which the effects of Nudoic 180 Tablet last: The effect of Nudoic 180 Tablet lasts for 15 to 24 hours.

What if you forget to take Nudoic 180 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Nudoic 180 Tablet at 20°C to 25°C (68°F to 77°F) in its original packaging to protect it from moisture and light.

Drug Warnings

  • Monitor your joints closely: This medicine can raise uric acid levels, which may cause gout. Report any sudden joint pain, swelling, or redness to your doctor immediately.
  • Be alert for tendon issues: There is a small risk of tendon rupture or injury while taking this medicine. Avoid strenuous physical activity if you feel sudden pain in your tendons.
  • Keep track of your blood work: Your doctor will likely schedule routine blood tests to check your liver function and uric acid levels. Make sure to attend all appointments.
  • Check compatibility before starting new drugs: Always inform any healthcare provider that you are taking Nudoic 180 Tablet before starting any new prescription or over-the-counter medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Simvastatin and Pravastatin (cholesterol medications): Combining these with Nudoic 180 Tablet can significantly increase the levels of these statins in your blood, raising the risk of muscle pain and weakness.
Bempedoic acidMoxifloxacin
Severe
Bempedoic acidPrednisolone
Severe

Drug-Drug Interactions

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Bempedoic acidMoxifloxacin
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and Moxifloxacin can increase the risk of tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Moxifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon (back of the ankle, shoulder, or biceps), consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidPrednisolone
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and Prednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Prednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Nudoic 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidNalidixic acid
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and nalidixic acid can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Nalidixic acid if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Nudoic 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidCortisone
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and Cortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Cortisone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of joints, consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGatifloxacin
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and gatifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Gatifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor immediately. Avoid or limit exercising or using the impacted area. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGemifloxacin
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and Gemifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Gemifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidTriamcinolone
Severe
How does the drug interact with Nudoic 180 Tablet:
Taking Nudoic 180 Tablet with Triamcinolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction between Nudoic 180 Tablet and triamcinolone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Nudoic 180 Tablet and consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidFludrocortisone
Severe
How does the drug interact with Nudoic 180 Tablet:
Taking Nudoic 180 Tablet with Fludrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Fludrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation in joints, consult a doctor. Exercising or using the injured area should also be avoided Do not discontinue any medications without consulting a doctor.
Bempedoic acidSimvastatin
Severe
How does the drug interact with Nudoic 180 Tablet:
Using Simvastatin together with Nudoic 180 Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Co-administration of Simvastatin and Nudoic 180 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any muscle pain, weakness, fever, dark urine, joint pain or swelling, vomiting, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Bempedoic acidDeflazacort
Severe
How does the drug interact with Nudoic 180 Tablet:
Co-administration of Nudoic 180 Tablet and Deflazacort can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Nudoic 180 Tablet can be taken with Deflazacort if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Nudoic 180 Tablet when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Nudoic 180 Tablet is used to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).
Nudoic 180 Tablet works by blocking the production of cholesterol in the liver. Thereby, it helps treat high cholesterol.
Do not discontinue Nudoic 180 Tablet without consulting your doctor, as it could lead to a rise in cholesterol. To get effective results, continue taking Nudoic 180 Tablet for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty while taking Nudoic 180 Tablet .
Tendon problems may happen in people taking Nudoic 180 Tablet . Consult the doctor if you experience pain, swelling, inflammation and tears of tendons, including Achilles (back of ankle), arm and shoulder. The risk of tendon problems may be increased if you are above 60 years of age, have renal problems, have had tendon problems or are taking antibiotics or corticosteroids.
Nudoic 180 Tablet can sometimes affect the liver. While it's generally safe, some people may have slightly elevated liver enzymes. These usually go back to normal on their own. If you notice any signs of liver problems, like yellowing of the skin or dark urine, talk to your doctor right away.
Your doctor may not prescribe Nudoic 180 Tablet if you have a history of tendon problems, severe liver problems, or if you're pregnant or breastfeeding. It can also interact with certain other medications. If you have any of these conditions, talk to your doctor before starting Nudoic 180 Tablet .
Take it with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.
LDL cholesterol is often called "bad cholesterol" because it can clog your arteries. This can make it harder for blood to reach your heart, increasing your risk of heart problems.
HDL cholesterol is often called "good cholesterol" because it helps clear out bad cholesterol. Higher levels of HDL can be good for your heart health. But it's important to manage both good and bad cholesterol for a healthy heart.
The only way to know whether you have high cholesterol is to get your cholesterol checked. Your health professional can do a simple blood test. This is called a lipid profile.
A healthy level of total cholesterol is below 5mmol/L. HDL (good cholesterol) is above 1.0mmol/L for men or above 1.2mmol/L for women. non-HDL (bad cholesterol) is below 4mmol/L.
High cholesterol can increase your risk of heart problems. It can build up in your arteries and cause problems like heart attacks. If you have symptoms like chest pain, shortness of breath, or fatigue, see a doctor. They can check your cholesterol and recommend treatment.
Lifestyle changes can help Nudoic 180 Tablet work better. Eat healthy, exercise regularly, maintain a healthy weight, quit smoking, limit alcohol, and manage stress. These changes can help lower your cholesterol and reduce your risk of heart problems.
While Nudoic 180 Tablet is generally well-tolerated, some people may experience side effects such as muscle pain, joint pain, fatigue, or digestive issues. If you experience any adverse effects, talk to your doctor.
Yes, Nudoic 180 Tablet is generally safe for people with diabetes. However, it's important to monitor your blood sugar levels closely while taking this medication.
If you have mild to moderate kidney problems, you may still be able to take Nudoic 180 Tablet . However, it's important to discuss this with your doctor, as your dosage may need to be adjusted.
No, Nudoic 180 Tablet is not known to cause weight gain.
Yes, Nudoic 180 Tablet can be taken with other cholesterol-lowering medications if prescribed by the doctor.
High cholesterol can be caused by many things, including age, family history, diet, lack of exercise, smoking, being overweight, and having conditions like diabetes or thyroid problems.
It depends on how risky you are of having heart problems. If you have a lot of things that can increase your risk, you might need to check it more often.
Yes, Nudoic 180 Tablet is often prescribed for people who experience muscle pain or other side effects from statins. It works differently than statins to lower cholesterol. Talk to your doctor to see if this is the right option for you.
There are no specific food restrictions or major drug-food interactions associated with Nudoic 180 Tablet . However, it is highly recommended to follow a cholesterol-lowering, low-fat diet to get the maximum benefit from your treatment. Talk to your doctor for personalised dietary advice.
While muscle spasms can occur, Nudoic 180 Tablet does not typically cause the same high rate of muscle pain as statins because of how it is processed in the body. If you develop unexplained muscle pain, weakness, or tenderness, talk to your doctor.
No, you should not take Nudoic 180 Tablet if you are pregnant or planning to become pregnant, as it may harm your developing baby. If you become pregnant while taking this medication, stop taking it and talk to your doctor immediately.
Moderate alcohol consumption is generally acceptable, but excessive drinking can increase the risk of liver strain when combined with cholesterol medications. Talk to your doctor or pharmacist about safe levels of alcohol intake for you.
This medicine can increase the levels of uric acid in your blood, which can sometimes lead to gout, a type of painful joint inflammation. If you have a history of gout or experience sudden joint pain, talk to your doctor.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.11743 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 211616S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A620020 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Bempedoic Acid [Product Information]. 2024. [Accessed on 05 Mar. 2025]Check here
  5. Daiichi Sankyo UK Limited. Nilemdo 180 mg film‑coated tablets: Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; last updated 07 Jul 2025 [Accessed on 2025 Dec 30]Check here
  6. Elani Streja, Dan A. Streja. Management of Dyslipidemia in the Elderly. NIH National Library of Medicine. National Center for Biotechnology Information. Endotext [Internet]. September 2020. [Accessed on 4th August 2022]Check here
  7. Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [Accessed on 2025 Dec 30]Check here

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - NUD0048
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