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compositionComposition:ETORICOXIB-90MG+VITAMIN D3-600IU
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Prescription Medicine
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Nucoxia D3 Capsule is an NSAID medicine used in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. This combination medicine works by reducing prostaglandin production, thus alleviating the pain and swelling that occurs in joints and muscles. You may experience common side effects like stomach pain, dizziness, headache, fatigue, and flatulence.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

ETORICOXIB-90MG+VITAMIN D3-600IU

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nucoxia D3 Capsule

Nucoxia D3 Capsule is a prescription medicine used to relieve pain, inflammation, and stiffness associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It combines a pain-relieving anti-inflammatory medicine with vitamin D3, which helps maintain healthy bones by improving calcium absorption. Together, they help reduce joint pain, improve mobility, and support overall bone health.

Take Nucoxia D3 Capsule exactly as prescribed, usually once daily at the same time each day to maintain consistent levels in your body. You can take it with or without food, although taking it with food may help if you experience stomach discomfort. Following a balanced diet rich in calcium and vitamin D, maintaining a healthy weight, and performing regular low-impact exercises such as walking or stretching can further support joint and bone health.

While taking Nucoxia D3 Capsule , you may experience mild side effects such as dizziness, stomach pain, indigestion, headache, or swelling of the feet and ankles. These effects are usually temporary, but seek immediate medical attention if you develop severe chest pain, shortness of breath, black or bloody stools, vomiting blood, yellowing of the skin or eyes, or signs of a serious allergic reaction.

Before starting Nucoxia D3 Capsule , tell your doctor if you have high blood pressure, heart disease, stomach ulcers, liver disease, kidney disease, inflammatory bowel disease, or a history of allergic reactions to NSAIDs. Do not take Nucoxia D3 Capsule if you have active stomach or intestinal bleeding, severe heart failure, severe liver disease, or are allergic to etoricoxib or other similar pain-relieving medicines. Your doctor will determine whether Nucoxia D3 Capsule is suitable for you.

Nucoxia D3 Capsule may interact with blood thinners, diuretics (water pills), blood pressure medicines, lithium, methotrexate, and low-dose aspirin, which may increase the risk of side effects or affect treatment. Avoid alcohol and smoking, as they can increase the risk of stomach irritation and ulcers. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your healthcare provider before using Nucoxia D3 Capsule .

Uses of Nucoxia D3 Capsule

Nucoxia D3 Capsule is used in the treatment of Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Gout. The detailed uses of Nucoxia D3 Capsule are as follows:

  • Osteoarthritis: Helps reduce the daily pain, stiffness, and localized swelling in the joints, making it easier to perform everyday movements.
  • Rheumatoid arthritis: Works to manage chronic joint inflammation, pain, and swelling associated with autoimmune joint conditions.
  • Ankylosing spondylitis: Relieves pain and progressive stiffness in the spine, helping to improve flexibility and comfort.
  • Bone weakness associated with joint pain: Provides targeted support for bone mineral health while simultaneously managing active joint pain and inflammation.

Key Benefits

Nucoxia D3 Capsule helps relieve joint pain and inflammation while supporting bone health. By combining pain relief with vitamin D support, it helps improve mobility and promotes overall musculoskeletal well-being.

Benefits may include:

• Helps relieve joint pain, stiffness, and inflammation.
• Supports comfortable movement and improved daily mobility.
• Helps maintain healthy vitamin D levels, which are important for bone health.
• Supports bone strength and overall musculoskeletal function.
• May help improve comfort during daily activities and rest by reducing pain flare-ups.
• Promotes long-term joint and bone health when used as part of an appropriate treatment plan.

Side effects of Nucoxia D3 Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.

Directions for Use

  • Nucoxia D3 Capsule can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the whole Nucoxia D3 Capsule with a glass of water.
  • Do not break, chew, or crush it.

How Nucoxia D3 Capsule Works

Nucoxia D3 Capsule contains Etoricoxib and Vitamin D3. Etoricoxib: It helps relieve pain, swelling, and stiffness by reducing the substances in the body that cause inflammation. This helps improve comfort and mobility in people with joint and muscle conditions. Vitamin D3: It helps the body absorb calcium effectively, supporting strong and healthy bones. It also helps maintain normal bone health, which is especially important in people with long-term joint problems.
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Alcohol

Caution

Caution is advised while taking alcohol with Nucoxia D3 Capsule . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Nucoxia D3 Capsule is not recommended for use in pregnancy. If you become pregnant while on Nucoxia D3 Capsule , stop taking Nucoxia D3 Capsule and immediately consult your physician.

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Breast Feeding

Caution

Not enough information is available on whether Nucoxia D3 Capsule is safe to use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Sometimes Nucoxia D3 Capsule may cause dizziness and affect your ability to drive. Avoid driving if you experience any giddiness or drowsiness.

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Liver

Caution

Nucoxia D3 Capsule should be used with caution in patients with liver disease. Please consult your doctor if you have any concerns.

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Kidney

Caution

Nucoxia D3 Capsule should be used with caution in patients with kidney disease. Please consult your doctor if you have any concerns.

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Children

Unsafe

Nucoxia D3 Capsule is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

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Heart

Unsafe

Nucoxia D3 Capsule should not be taken if you have pre-existing heart disease. Talk to your doctor before use if you have any medical conditions or concerns.

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Geriatrics

Caution

Nucoxia D3 Capsule should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Nucoxia D3 Capsule

If you accidentally take more than your prescribed dose, seek immediate medical attention or contact your local emergency service. Symptoms of an overdose may include severe stomach pain, vomiting, or extreme dizziness.

Diet & Lifestyle Advise

  • Eat calcium-rich foods: Include dairy products, leafy green vegetables, and fortified foods in your diet to support the bone-strengthening effects of Nucoxia D3 Capsule .
  • Stay active with low-impact exercise: Engage in gentle activities like walking, swimming, or stationary cycling to keep your joints flexible and strengthen the surrounding muscles.
  • Manage your weight: Maintaining a healthy weight helps reduce the physical load and wear-on-tear on weight-bearing joints like your knees and hips.
  • Limit your salt intake: Reducing sodium in your diet can help minimize fluid retention and swelling, which is a potential side effect of this medication.
health query

Have a query?

How Soon It Starts Working

The time required for Nucoxia D3 Capsule to start to work: The time required for Nucoxia D3 Capsule to show its action is unknown. The time for which the effects of Nucoxia D3 Capsule last: The duration of action for Nucoxia D3 Capsule is clinically unknown.

What if you forget to take Nucoxia D3 Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Nucoxia D3 Capsule tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Monitor your blood pressure regularly: Check your blood pressure periodically while taking Nucoxia D3 Capsule , as it may occasionally cause blood pressure levels to increase.
  • Avoid taking other NSAIDs: Do not take other non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, unless specifically advised by your doctor, as this may increase the risk of stomach irritation, ulcers, and bleeding.
  • Inform healthcare providers before procedures: Tell your doctor, dentist, or surgeon that you are taking Nucoxia D3 Capsule before undergoing any medical, surgical, or dental procedure.
  • Limit alcohol intake: Avoid or limit alcohol consumption while taking Nucoxia D3 Capsule to help reduce the risk of stomach ulcers and gastrointestinal bleeding.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Nucoxia D3 Capsule may increase the risk of serious stomach bleeding.
  • Diuretics (water pills) and blood pressure medicines: Nucoxia D3 Capsule may reduce the effectiveness of these medicines and increase the risk of kidney problems.
  • Non-steroidal anti-inflammatory medicines (e.g., Aspirin): Combining aspirin with Nucoxia D3 Capsule may significantly increase the risk of stomach irritation, ulcers, and bleeding.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Nucoxia D3 Capsule when used as directed. 

 

No clinically significant drug interactions are known with Nucoxia D3 Capsule when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Nucoxia D3 Capsule belongs to the group of NSAIDs primarily used to relieve pain. Nucoxia D3 Capsule alleviates the pain and swelling that occurs in joints and muscles. Nucoxia D3 Capsule is used in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout.
Nucoxia D3 Capsule works by reducing the production of prostaglandins and relieving inflammation and pain. Nucoxia D3 Capsule also enhances bone health and strength.
It is not known if Nucoxia D3 Capsule affects fertility but Nucoxia D3 Capsule is not recommended for use in women planning to get pregnant.
Nucoxia D3 Capsule contains a potent pain killer and an active form of Vitamin D. It cannot be used to replace calcium and should never be used as a calcium supplement.
Please see an orthopaedic doctor if you have had a fracture. Nucoxia D3 Capsule is used in case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead.
When taking Nucoxia D3 Capsule , consult your doctor about your allergies and any past or current health conditions, especially if you have heart disease, high blood pressure, kidney or liver problems, a history of strokes, or bleeding issues. Let your doctor know about any other medications you are taking, particularly blood pressure medicines, blood thinners, or pain relievers like other NSAIDs, as these might interact with Nucoxia D3 Capsule . If you have bone problems, mention this to your doctor because Nucoxia D3 Capsule contains Vitamin D3, which can affect calcium metabolism in your body. Regular monitoring of kidney function, liver enzymes, and blood pressure may be necessary. Also, discuss with your doctor about the duration of Nucoxia D3 Capsule use, especially for long-term management, and any signs of side effects. Be sure to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
The common side effects of Nucoxia D3 Capsule include stomach pain, dizziness, headache, fatigue, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
Taking aspirin with Nucoxia D3 Capsule may increase the risk of stomach irritation, ulcers, and bleeding. If you take low-dose aspirin for heart protection, do not stop it without consulting your doctor. Your doctor may recommend additional stomach protection or another pain relief option depending on your condition.
Yes, you can take Nucoxia D3 Capsule with or without food. If you experience mild stomach upset, taking it with a meal or a glass of milk may help reduce discomfort. Talk to your doctor if stomach irritation persists.
You must use caution, as Nucoxia D3 Capsule can sometimes cause your blood pressure to rise. Your doctor will likely want to monitor your blood pressure closely during treatment. Talk to your doctor before starting this medication if you have high blood pressure.
Dizziness can sometimes occur when taking Nucoxia D3 Capsule . If you feel lightheaded, avoid driving, cycling, or operating machinery until the feeling passes. Talk to your doctor if the dizziness is severe or does not go away.
No, Nucoxia D3 Capsule is generally not recommended during pregnancy, especially in the last three months, as it may affect the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor to discuss safer alternatives.
It is highly recommended to limit or avoid alcohol while on this medication. Alcohol can significantly increase the risk of stomach irritation, ulcers, and bleeding when combined with pain relievers. Talk to your doctor for personalized safety advice.
Because Nucoxia D3 Capsule already contains a bone-supporting vitamin component, taking additional vitamin supplements might lead to excessively high levels in your body. Always share a complete list of your current supplements and talk to your doctor before starting Nucoxia D3 Capsule .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.10617 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Medicine Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Clinical Reference Document. [Accessed on 02 Jun. 2026]Check here
  4. National Center for Biotechnology Information (NCBI). Pmc1661646 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Cholecalciferol,Vitamin D3 Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  7. Drugs.com Clinical Review Team. Arcoxia Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India
Other Info - NUC0103

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