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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nucloba 5mg Dt Tablet is used to treat epilepsy (fits) and severe anxiety over a short period. Also, it is used in combination with other medicines to treat schizophrenia (a mental illness). It prevents fits by stabilizing the electrical activity of nerve cells in the brain. Also, it calms nerve cells and helps in reducing anxiety and induces sleep. Some people may experience side effects such as restlessness, irritability, drowsiness, constipation, aggressive behaviour, tiredness or breathing problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CLOBAZAM-5MG

Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Nucloba 5mg Dt Tablet

Nucloba 5mg Dt Tablet is used to treat epilepsy (fits) and severe anxiety over a short period. Also, Nucloba 5mg Dt Tablet is used in combination with other medicines to treat schizophrenia (a mental illness). Epilepsy (fits) is a disorder in which there is a sudden, uncontrolled disturbance in the electrical activity of nerve cells in the brain. Anxiety is a mental health disorder associated with fear, worry and excessive nervousness. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Nucloba 5mg Dt Tablet works by increasing the release of GABA (a chemical messenger that acts as a nerve-calming agent) in the brain by acting on GABA receptors. Thereby, Nucloba 5mg Dt Tablet prevents fits by stabilizing the electrical activity of nerve cells in the brain. Also, Nucloba 5mg Dt Tablet calms nerve cells and helps in reducing anxiety and induces sleep.

Take Nucloba 5mg Dt Tablet as prescribed. Your doctor will advise how often you take Nucloba 5mg Dt Tablet based on your medical condition. Some people may experience restlessness, irritability, drowsiness, constipation, aggressive behaviour, tiredness or breathing problems. Most of these side effects of Nucloba 5mg Dt Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Nucloba 5mg Dt Tablet or any other medicines, please tell your doctor. Nucloba 5mg Dt Tablet is not recommended for children below 6 years of age. Do not take Nucloba 5mg Dt Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Nucloba 5mg Dt Tablet should be used with caution in elderly patients above 65 years as there is an increased risk of adverse reactions such as dizziness, muscle weakness and drowsiness. Avoid taking Nucloba 5mg Dt Tablet if you have myasthenia gravis (muscle weakness), sleep apnoea (breathing stops and starts repeatedly), breathing or liver problems. Do not take Nucloba 5mg Dt Tablet with opioids as it may cause breathing problems, drowsiness, coma and even death.

Uses of Nucloba 5mg Dt Tablet

Nucloba 5mg Dt Tablet is used in the treatment of epilepsy and anxiety disorders. The detailed uses of Nucloba 5mg Dt Tablet are as follows:

  • Seizure Control: Nucloba 5mg Dt Tablet is commonly prescribed to manage seizures in epilepsy patients, offering an effective anticonvulsant benefit.
  • Anxiety Disorders: Nucloba 5mg Dt Tablet acts as an anxiolytic, helping to alleviate symptoms associated with various anxiety disorders.
  • Muscle Relaxation: Nucloba 5mg Dt Tablet provides muscle relaxation, making it suitable for treating muscle spasms and reducing associated discomfort.
  • Sleep Disorder Management: Nucloba 5mg Dt Tablet is used for short-term relief of sleep disturbances, improving sleep quality by reducing anxiety and tension.
  • Adjuvant Therapy: Nucloba 5mg Dt Tablet can serve as an adjunct treatment alongside other medications for complex seizure disorders, enhancing the overall therapeutic effect.

Directions for Use

• Take Nucloba 5mg Dt Tablet with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use. • Swallow Nucloba 5mg Dt Tablet as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

Nucloba 5mg Dt Tablet is an anxiolytic drug (reduces anxiety) that is used to treat epilepsy (fits), severe anxiety over a short period. Nucloba 5mg Dt Tablet prevents fits by stabilizing the electrical activity of nerve cells in the brain. Also, Nucloba 5mg Dt Tablet calms nerve cells and helps in reducing anxiety over a short period and induces sleep. Additionally, Nucloba 5mg Dt Tablet can also be used in combination with other medicines to treat schizophrenia (a mental illness).

How Nucloba 5mg Dt Tablet Works

Nucloba 5mg Dt Tablet is used in combination with other medicines to treat schizophrenia (a mental illness). Epilepsy (fits) is a disorder in which there is a sudden, uncontrolled disturbance in the electrical activity of nerve cells in the brain. Anxiety is a mental health disorder associated with fear, worry and excessive nervousness. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Nucloba 5mg Dt Tablet works by increasing the release of GABA (a chemical messenger that acts as a nerve-calming agent) in the brain by acting on GABA receptors. Thereby, Nucloba 5mg Dt Tablet prevents fits by stabilizing the electrical activity of nerve cells in the brain. Also, Nucloba 5mg Dt Tablet calms nerve cells and helps in reducing anxiety and induces sleep.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nucloba 5mg Dt Tablet

Do not take more than the prescribed dose of Nucloba 5mg Dt Tablet as it may cause overdose. Clobazam overdose can be fatal if it is taken with opiod medicine, alcohol, or other drugs that cause slow breathing or drowsiness. The symptoms of overdose include confusion, extreme drowsiness or weakness, loss of consciousness or slow breathing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Nucloba 5mg Dt Tablet if you are known to be allergic to Nucloba 5mg Dt Tablet . Nucloba 5mg Dt Tablet is not recommended for children below 6 years of age. Do not take Nucloba 5mg Dt Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Nucloba 5mg Dt Tablet should be used with caution in elderly patients above 65 years as there is an increased risk of adverse reactions such as dizziness, muscle weakness and drowsiness. If you have depression, spinal or cerebellar ataxia (problems in controlling movements), hallucinations, delusions (misbelief), liver or kidney problems, inform your doctor before taking Nucloba 5mg Dt Tablet . Avoid taking Nucloba 5mg Dt Tablet if you have myasthenia gravis (muscle weakness), sleep apnoea (breathing stops and starts repeatedly), breathing or liver problems. Do not take Nucloba 5mg Dt Tablet with opioids as it may cause breathing problems, drowsiness, coma and even death.

Drug-Drug Interactions

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ClobazamSodium oxybate
Critical

Drug-Drug Interactions

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ClobazamSodium oxybate
Critical
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet can enhance the sedative effects of Sodium oxybate on the central nervous system.

How to manage the interaction:
Co-administration of Clarithromycin and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like respiratory depression, low blood pressure, fainting, coma, and even death, a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nucloba 5mg Dt Tablet:
When Thioridazine is taken with Nucloba 5mg Dt Tablet, may increase the blood levels of thioridazine and cause an irregular heart rhythm.

How to manage the interaction:
Co-administration of Nucloba 5mg Dt Tablet and Thioridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClobazamEsketamine
Severe
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet with Esketamine may increase the severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Nucloba 5mg Dt Tablet can be taken with esketamine if prescribed by the doctor. Until the next day avoid driving or operating hazardous machinery after receiving treatment with esketamine. However, consult a doctor if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, impairment in judgment, reaction speed, and motor coordination, it is important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nucloba 5mg Dt Tablet:
Modafinil may increase the blood levels of Nucloba 5mg Dt Tablet. This may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Nucloba 5mg Dt Tablet can be taken with modafinil if prescribed by the doctor. Consult the prescriber if you experience side effects such as tiredness, drowsiness, constipation, drooling, and breathing difficulties. Use caution when getting up from a sitting or lying position.
ClobazamOxycodone
Severe
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet with Oxycodone may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult the doctor if you are taking Nucloba 5mg Dt Tablet with Oxycodone. Avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the doses and duration prescribed by your doctor.
ClobazamHydrocodone
Severe
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet with Hydrocodone may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult the doctor if you are taking Nucloba 5mg Dt Tablet with Hydrocodone. Avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the doses and duration prescribed by your doctor.
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Tapentadol together with Nucloba 5mg Dt Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Nucloba 5mg Dt Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nucloba 5mg Dt Tablet:
Using Morphine together with Nucloba 5mg Dt Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Nucloba 5mg Dt Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClobazamPethidine
Severe
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet with Meperidine can increase the risk of breathing problems.

How to manage the interaction:
Taking Pethidine with Nucloba 5mg Dt Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. This means that taking Nucloba 5mg Dt Tablet and opioids together can make it more likely to have trouble breathing. Talk to your doctor about other options that may not have this interaction. Do not stop using any medications without talking to a doctor.
ClobazamCodeine
Severe
How does the drug interact with Nucloba 5mg Dt Tablet:
Co-administration of Nucloba 5mg Dt Tablet with Codeine may lead to serious side effects like respiratory distress.

How to manage the interaction:
Consult the doctor if you are taking Nucloba 5mg Dt Tablet with Codeine. Avoid driving or operating hazardous machinery. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, consult a doctor. Do not exceed the doses and duration prescribed by your doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a regular sleep pattern.

  • Maintain a low-carbohydrate and high-fat diet which includes seafood, avocado, cheese, coconut oil, eggs, poultry and meat, olive oil, berries, butter, cream, dark chocolate, nuts and seeds as it helps to reduce fits.

  • Do regular exercise and maintain a healthy body weight.

  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS
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Alcohol

Unsafe

Avoid consumption of alcohol with Nucloba 5mg Dt Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Nucloba 5mg Dt Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the second and third trimesters as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Nucloba 5mg Dt Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Nucloba 5mg Dt Tablet may cause dizziness, double vision or drowsiness in some people. It is an offence to drive if Nucloba 5mg Dt Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Nucloba 5mg Dt Tablet .

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Liver

Caution

Take Nucloba 5mg Dt Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Nucloba 5mg Dt Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Nucloba 5mg Dt Tablet is not recommended for children below 6 years. However, Nucloba 5mg Dt Tablet may be used in children above 6 years in dose and duration as prescribed by a doctor.

Have a query?

FAQs

Nucloba 5mg Dt Tablet is used to treat epilepsy (fits) and severe anxiety over a short period. It works by increasing the release of GABA (a chemical messenger that acts as a nerve-calming agent) in the brain and calming nerve cells.

No, you are not recommended to take Nucloba 5mg Dt Tablet with opioids as co-administration of these medicines may cause breathing problems, drowsiness, coma and even death. However, before using Nucloba 5mg Dt Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

No, Nucloba 5mg Dt Tablet is not recommended for use during pregnancy especially in the second and third trimesters as it may cause adverse effects in the baby such as cleft lip, changes in heart rate, movements, muscle weakness, breathing problems, drowsiness or drop in body temperature. Nucloba 5mg Dt Tablet may cause withdrawal symptoms such as shaking or nervous excitement in the baby if taken during late pregnancy. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking Nucloba 5mg Dt Tablet .

No, you are not recommended to stop taking Nucloba 5mg Dt Tablet without consulting your doctor as it may cause depression, anxiety, confusion, difficulty in sleeping and loss of appetite. Therefore, take Nucloba 5mg Dt Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Nucloba 5mg Dt Tablet , please consult your doctor so that the dose may be gradually reduced.

Yes, Nucloba 5mg Dt Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Nucloba 5mg Dt Tablet only in dose and duration as advised by your doctor.

No, Nucloba 5mg Dt Tablet does not cure epilepsy. Nucloba 5mg Dt Tablet only helps in controlling seizures (fits). There is no cure for epilepsy but treatment at an early stage can make a huge difference as prolonged or uncontrolled fits may result in brain damage.

Country of origin

India

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - NUC0131

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