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compositionComposition:DAROLUTAMIDE-300MG
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Nubeqa Tablet 112's (7x16's) is a non-steroidal androgen receptor inhibitor used for the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic hormone-sensitive prostate cancer (mHSPC) in combination with docetaxel. It works by blocking the action of androgens (male hormones) and helps slow down or stop the growth of prostate cancer cells. Possible side effects may include abnormal liver function test, decreased white blood cell count (neutropenia), tiredness, pain in your arms, hands, legs, or feet, and rash. Before starting Nubeqa Tablet 112's (7x16's), let the doctor know if you are taking any other medicines or have pre-existing medical conditions.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DAROLUTAMIDE-300MG

Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nubeqa Tablet 112's (7x16's)

Nubeqa Tablet 112's (7x16's) is a prescription medicine used together with androgen deprivation therapy (ADT) to treat certain types of prostate cancer. It is used when the cancer has not spread to other parts of the body but no longer responds to testosterone-lowering treatment (non-metastatic castration-resistant prostate cancer), and it is also used when the cancer has spread to other parts of the body and still responds to hormone therapy (metastatic hormone-sensitive prostate cancer), often in combination with other cancer treatments.

To get the best results from Nubeqa Tablet 112's (7x16's), you must take it consistently and exactly as your doctor directs. You must always take this medicine with food, as a meal or snack helps your body absorb the drug properly. Alongside this treatment, maintaining a balanced diet and performing light, doctor-approved physical activities can support your physical strength and daily energy levels.

Like most medications, Nubeqa Tablet 112's (7x16's) can cause side effects. While common issues like feeling very tired or developing a skin rash are usually mild, you must seek medical attention if you notice signs of serious complications, such as chest pain or breathing difficulties. Always discuss any unusual symptoms with your doctor.

Before you start taking Nubeqa Tablet 112's (7x16's), tell your healthcare provider if you have a history of liver damage, kidney disease, or heart conditions. Do not take this medicine if you are pregnant, planning to become pregnant, or are a woman of childbearing potential, as it can cause serious harm to an unborn baby.

This medicine can interact with other prescription drugs, over-the-counter products, or herbal supplements, which may change how the treatment works or increase side effects. If you are a male with a female partner who is able to get pregnant, you must use highly effective birth control during treatment and for one week after your final dose. Elderly patients should consult their doctor to ensure this treatment aligns safely with their other health needs.

Uses of Nubeqa Tablet 112's (7x16's)

Nubeqa Tablet 112's (7x16's) may be used for the following types of prostate cancer:

  • Non-metastatic castration-resistant prostate cancer: Nubeqa Tablet 112's (7x16's) helps by blocking signals that tell cancer cells to grow, specifically in cases where the prostate cancer has not spread to other areas of the body but has stopped responding to traditional hormone therapies.
  • Metastatic hormone-sensitive prostate cancer: When used alongside other therapies, Nubeqa Tablet 112's (7x16's) helps slow down or stop the spread of prostate cancer to other organs in patients whose cancer still responds to hormone-lowering treatments.

Key Benefits

Using Nubeqa Tablet 112's (7x16's) as prescribed helps slow the progression of prostate cancer and supports continued daily functioning. Here are the key benefits you can expect:

  • Slows cancer progression: Nubeqa Tablet 112's (7x16's) helps slow down the progression of prostate cancer, allowing you to maintain your physical function and daily activities for longer. By delaying the spread of cancer cells, this medicine helps reduce the risk of painful complications, such as bone pain or fractures, which are common as the disease advances.
  • Convenient treatment: Because Nubeqa Tablet 112's (7x16's) is an oral tablet taken at home, it offers a convenient treatment option that reduces the need for frequent clinic visits for intravenous therapies. This allows you to manage your condition with minimal disruption to your daily routine.

Directions for Use

  • Nubeqa Tablet 112's (7x16's) can be taken with food.
  • Nubeqa Tablet 112's (7x16's) is usually taken twice a day, or as prescribed by your doctor.
  • Swallow Nubeqa Tablet 112's (7x16's) as a whole with a glass of water.
  • Do not break, crush or chew it.

How Nubeqa Tablet 112's (7x16's) Works

Nubeqa Tablet 112's (7x16's) contains darolutamide and belongs to a group of medicines known as androgen receptor inhibitors. Testosterone, a male hormone, can bind to proteins called androgen receptors on prostate cancer cells, acting as fuel that stimulates the cancer to grow and multiply. Nubeqa Tablet 112's (7x16's) works by attaching to these androgen receptors and blocking testosterone from binding to them. By cutting off this hormonal signal, the medicine deprives the cancer cells of the fuel they need, which helps slow down the growth and spread of the cancer.
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Alcohol

Caution

It is unknown if alcohol interacts with Nubeqa Tablet 112's (7x16's). Please consult a doctor if you have any concerns.

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Pregnancy

Unsafe

Nubeqa Tablet 112's (7x16's) should not be taken during pregnancy as it can cause harm to the foetus and miscarriage (loss of pregnancy).

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Breast Feeding

Not applicable

It is not known if Darolutamide passes into breast milk. However, Nubeqa Tablet 112's (7x16's) is only for use in men. Women should not take this medication.

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Driving

Consult your doctor

It is not known if Nubeqa Tablet 112's (7x16's) affects your ability to drive. Drive only if you are alert after taking Nubeqa Tablet 112's (7x16's).

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Liver

Caution

Inform your doctor if you have liver impairment. Your doctor will weigh the benefits and any potential risks before prescribing Nubeqa Tablet 112's (7x16's).

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Kidney

Caution

Inform your doctor if you have kidney impairment. Your doctor will weigh the benefits and any potential risks before prescribing Nubeqa Tablet 112's (7x16's).

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Children

Unsafe

Nubeqa Tablet 112's (7x16's) is not recommended for use in children as the safety and efficacy of this medicine are not established.

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Heart

Caution

Nubeqa Tablet 112's (7x16's) should be used with caution in patients with heart problems. Therefore, please inform your doctor if your have any heart problems before prescribing Nubeqa Tablet 112's (7x16's).

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Geriatrics

Consult your doctor

Limited information is available on the use of Nubeqa Tablet 112's (7x16's) in elderly patients. Please consult a doctor if you have any concerns about its use in elderly patients.

What if I have taken an overdose of Nubeqa Tablet 112's (7x16's)

If you accidentally take more than your prescribed dose of Nubeqa Tablet 112's (7x16's), call emergency services or go to the nearest emergency department immediately. Take the medicine container or prescription with you if possible so healthcare professionals know what was taken.

Diet & Lifestyle Advise

  • Support bone health: Hormone therapies can sometimes weaken your bones. Focus on eating foods rich in calcium and vitamin D, such as dairy products, leafy greens, and fortified foods, and discuss potential supplements with your doctor.
  • Combat fatigue with activity: Feeling tired is a common side effect. Engaging in light, regular physical activity, such as walking or gentle strength training, can help boost your energy levels and preserve muscle mass.
  • Protect your heart: Eat a heart-healthy diet low in saturated fats and sodium to manage your blood pressure and cardiovascular health, as some hormone treatments can affect your heart.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidney function and help manage mild side effects.
  • Emotional support matters: Living with prostate cancer and taking long-term treatment can feel physically and emotionally challenging. Stay in close contact with your healthcare team, and seek support from family, friends, counsellors, or support groups whenever needed.
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How Soon It Starts Working

The time required for Nubeqa Tablet 112's (7x16's) to start to work: Nubeqa Tablet 112's (7x16's) ideally starts to show its action within 4-6 hours of administration. The time for which the effects of Nubeqa Tablet 112's (7x16's) last: The effect of Nubeqa Tablet 112's (7x16's) usually lasts for 10-15 hours.

What if you forget to take Nubeqa Tablet 112's (7x16's)

If you miss a dose of Nubeqa Tablet 112's (7x16's), take it with food as soon as you remember, as long as it is before your next scheduled dose. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Nubeqa Tablet 112's (7x16's) tablets at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Never take on an empty stomach: Always take Nubeqa Tablet 112's (7x16's) with a meal or snack, as food is required for the medicine to be properly absorbed into your body.
  • Use effective birth control: If you are sexually active with a female partner who can become pregnant, you must use highly effective birth control during treatment and for 1 week after your last dose.
  • Attend scheduled blood tests: Your doctor will order regular blood tests to monitor your liver function and overall health while you are taking this medicine.
  • Report heart symptoms immediately: Alert your doctor right away if you experience chest tightness, shortness of breath, or swelling in your legs.
  • Attend scheduled blood tests: Your doctor may regularly check your PSA levels and liver function during treatment to monitor how well Nubeqa Tablet 112's (7x16's) is working and to look for side effects.
  • Kidney monitoring: If you have kidney disease or reduced kidney function, your doctor may perform periodic kidney function tests during treatment.
  • Heart and blood pressure checks: Your blood pressure and cardiovascular health may be monitored regularly, especially if you have a history of heart disease.
  • Attend follow-up appointments: Keep all scheduled appointments, as your doctor may review your symptoms, side effects, medicines, and order scans such as CT, MRI, or bone scans when needed to assess your cancer.
  • Pregnancy handling warning: Women who are pregnant or may become pregnant should avoid direct contact with broken or crushed Nubeqa Tablet 112's (7x16's) tablets. If handling the tablets is unavoidable, disposable gloves should be worn and hands should be washed thoroughly afterwards.

verifiedApollotooltip
  • Certain seizure or tuberculosis medicines: Certain strong medications used for seizures or tuberculosis (such as carbamazepine or rifampin) can reduce the amount of Nubeqa Tablet 112's (7x16's) in your body, making it less effective.
  • Cholesterol-lowering medicines: Nubeqa Tablet 112's (7x16's) can increase the levels of certain cholesterol-lowering medications (such as statins) in your blood, which may increase your risk of muscle pain or weakness.

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verifiedApollotooltip
  • Take with food: Taking Nubeqa Tablet 112's (7x16's) without food significantly decreases its absorption, lowering the drug's effectiveness in fighting cancer. Always take it with a meal or snack.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Nubeqa Tablet 112's (7x16's) is used in the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC). It is also used in combination with docetaxel in the treatment of metastatic hormone-sensitive prostate cancer (mHSPC).
Nubeqa Tablet 112's (7x16's) contains Darolutamide, which inhibits the effects of androgens, the hormones that promote prostate cancer growth. By blocking androgen stimulation, Nubeqa Tablet 112's (7x16's) helps slow the progression of cancer and limits its spread.
Do not stop taking Nubeqa Tablet 112's (7x16's) without consulting your doctor, as it may reduce the medication’s effectiveness. To treat your condition effectively, continue taking Nubeqa Tablet 112's (7x16's) for as long as prescribed by your doctor.
Yes, Nubeqa Tablet 112's (7x16's) is intended for daily use as prescribed by your doctor. Follow the recommended dosage carefully, and do not skip or exceed it without medical guidance.
Nubeqa Tablet 112's (7x16's) is intended for use in men only. Women, especially those who are pregnant, may become pregnant, or are breastfeeding, should not take this medication.
In certain cases, Nubeqa Tablet 112's (7x16's) may lead to decreased fertility in men. However, you should not assume that your partner is unable to become pregnant. Please consult your doctor if you have any concerns regarding fertility.
Nubeqa Tablet 112's (7x16's) is better absorbed into the bloodstream when taken with food. Always take this medication with a meal, as directed by your doctor.
Taking higher doses than prescribed is ineffective and may cause side effects. Therefore, it's essential to follow the dosage instructions provided by your doctor to ensure safe and effective use.
Darolutamide is combined with docetaxel for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). This combination has been shown to improve the effectiveness of the medication compared to using docetaxel or Darolutamide alone.
Common side effects include abnormal liver function test, decreased white blood cell count (neutropenia), tiredness, pain in your arms, hands, legs, or feet, and rash. Seek medical care if the side effects persist or worsen.
Hair loss is not a commonly reported side effect of Nubeqa Tablet 112's (7x16's). However, other cancer treatments or hormone therapies used at the same time might cause hair thinning. Talk to your doctor or pharmacist if you experience changes in your hair.
If you vomit after taking your dose, do not take an extra tablet to replace it. Simply take your next scheduled dose at your normal time with food. Talk to your doctor or pharmacist if frequent vomiting prevents you from keeping your medicine down.
There is no direct interaction between Nubeqa Tablet 112's (7x16's) and alcohol, but alcohol can worsen side effects like fatigue and put extra stress on your liver. It is best to limit your alcohol intake during treatment. Talk to your doctor or pharmacist for personalised advice.
Nubeqa Tablet 112's (7x16's) may increase the risk of certain heart problems in some patients, including heart failure and abnormal heart rhythms, particularly in people who already have heart disease. Your doctor may monitor your blood pressure, heart symptoms, and overall cardiovascular health during treatment. Seek medical attention promptly if you develop chest pain, shortness of breath, swelling of the feet or legs, sudden weight gain, palpitations, or fainting.
No, Nubeqa Tablet 112's (7x16's) is not a traditional chemotherapy drug. It is a hormone therapy known as an androgen receptor inhibitor. It works by blocking the hormones that help prostate cancer cells grow, rather than directly killing fast-growing cells. Talk to your doctor for more details about how your treatment plan works.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Central Avenue, Hiranandani Estate, Thane – 400607, Maharashtra, India
Other Info - NUB0127
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