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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Novagesic-MR Tablet is used to treat spasticity (muscle stiffness and spasms) associated with pain. It contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol block prostaglandins (PGs), which cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, it helps to reduce muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

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Manufacturer/Marketer :

Carnation Pharmtech

Consume Type :

ORAL

Return Policy :

Not Returnable

About Novagesic-MR Tablet

Novagesic-MR Tablet is a combination medicine that contains pain relievers and muscle relaxants. It is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a muscle cramp or feel tight or stiff, like a knot.

Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, Novagesic-MR Tablet helps to reduce muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

Novagesic-MR Tablet is prescribed medication, and it should be taken as directed by the doctor. In some cases, you may experience common side effects such as vomiting, diarrhoea, headaches, drowsiness and ringing in your ears (tinnitus), fluctuations in blood pressure, dry mouth, stomach upsets, and a decrease or increase in heart rate. Most of these side effects do not require medical attention and will resolve gradually. If any of these effects persist, consult your doctor.

Avoid taking Novagesic-MR Tablet if you are allergic to any of its components. Before taking Novagesic-MR Tablet, tell your doctor about your medical history and other medications you are currently taking to rule out any possible side effects. Novagesic-MR Tablet is not recommended for use in pregnancy. If you are breastfeeding, consult your doctor before taking Novagesic-MR Tablet. This medicine may cause dizziness, so drive only if you are alert and focused. Novagesic-MR Tablet should not be given to children as safety has not been established. Avoid consuming alcohol while on treatment with Novagesic-MR Tablet as it could lead to liver damage.

Uses of Novagesic-MR Tablet

Novagesic-MR Tablet is used in the treatment of spasticity and associated muscle pain and stiffness. The detailed uses of Novagesic-MR Tablet are as follows:<br/>• Relieves muscle spasms: Novagesic-MR Tablet helps reduce involuntary muscle contractions and stiffness in conditions causing spasticity.<br/>• Reduces pain and inflammation: Novagesic-MR Tablet provides effective pain relief and reduces swelling in affected muscles and joints.<br/>• Improves mobility and comfort: By easing both pain and muscle tightness, Novagesic-MR Tablet supports better physical function and comfort.<br/>

Directions for Use

• Take Novagesic-MR Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Novagesic-MR Tablet aids in relieving muscle stiffness, spasms, and pain. Besides this, paracetamol reduces elevated temperature by altering the chemical messengers in the brain area that regulates body temperature.

How Novagesic-MR Tablet Works

Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Reducing Pain and Inflammation: Diclofenac, a non-steroidal anti-inflammatory medication (NSAID), effectively lowers pain and inflammation by inhibiting the formation of prostaglandins.Reducing fever: Paracetamol, an antipyretic, lowers fever by changing the chemical messengers in the brain that regulate body temperature.Muscle relaxation: Tizanidine, a muscle relaxant, operates in the brain and spinal cord to reduce muscular stiffness and spasms by decreasing the release of excitatory amino acids.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Novagesic-MR Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Novagesic-MR Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Novagesic-MR Tablet may include nausea, vomiting, low blood pressure, a slow or abnormal heartbeat, dizziness, small pupils, difficulty breathing, coma, restlessness or sleepiness, ulcer in your stomach or gut and liver damage. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Novagesic-MR Tablet if you are allergic to its components. Inform your doctor about all your medical conditions, especially if you have/ had hepatotoxicity, hypotension, renal dysfunction or renal toxicities, asthma, fluid retention, GI toxicity, rash, or thrombosis (blood clots). It is not recommended to take Novagesic-MR Tablet during pregnancy or whilst breastfeeding. Novagesic-MR Tablet may cause drowsiness and dizziness, so drive only when you are alert. Novagesic-MR Tablet is not recommended for children as safety and effectiveness have not been established. Do not stop taking Novagesic-MR Tablet unless your doctor tells you to. Treatment with Novagesic-MR Tablet should be stopped gradually. Stopping treatment suddenly may cause effects such as an increase in heart rate and high blood pressure.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Novagesic-MR Tablet:
Co-administration of Novagesic-MR Tablet with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Novagesic-MR Tablet with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Novagesic-MR Tablet:
Coadministration of Novagesic-MR Tablet with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Novagesic-MR Tablet with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Novagesic-MR Tablet:
Taking Fluvoxamine with Novagesic-MR Tablet it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Novagesic-MR Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Novagesic-MR Tablet:
Coadministration of Novagesic-MR Tablet with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Novagesic-MR Tablet with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Novagesic-MR Tablet:
Coadministration of Ciprofloxacin and Novagesic-MR Tablet together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Novagesic-MR Tablet together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Novagesic-MR Tablet:
Combining Novagesic-MR Tablet with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Novagesic-MR Tablet with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Novagesic-MR Tablet:
Co-administration of Novagesic-MR Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Novagesic-MR Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Novagesic-MR Tablet:
Coadministration of Novagesic-MR Tablet and bosentan can increase the risk of low blood pressure.

How to manage the interaction:
Although using Novagesic-MR Tablet and bosentan together can result in an interaction, they can be taken together if prescribed by your doctor. Consult your doctor if you experience dizziness, headaches, palpitations, or excessive sweating. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Novagesic-MR Tablet:
Co-administration of Novagesic-MR Tablet and Eplerenone may significantly increase eplerenone's blood levels and side effects.

How to manage the interaction:
Taking Novagesic-MR Tablet and Eplerenone together can lead to an interaction, it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, chest pain, and palpitations, contact your doctor immediately. Do not stop any medications without a doctor's consultation.
How does the drug interact with Novagesic-MR Tablet:
Coadministration of Buprenorphine with Novagesic-MR Tablet may increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Coadministration of Buprenorphine with Novagesic-MR Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, dizziness, palpitations, or sweating, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regular exercise helps muscle stretch, making them less likely to spasm, tear, and sprain. Mild activities such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Rest well, and get plenty of sleep.
  • Change your position at least every two hours to avoid developing pressure sores.
  • Hot or cold therapy can help treat muscle spasms.
  • Apply an ice pack or hot pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Caution

Avoid consumption of alcohol while taking Novagesic-MR Tablet as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Novagesic-MR Tablet is not recommended for use in pregnant women. If you are pregnant or planning pregnancy, consult your doctor before taking Novagesic-MR Tablet.

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Breast Feeding

Caution

Novagesic-MR Tablet is generally not recommended for use in breastfeeding mothers. If you are breastfeeding, consult your doctor before taking Novagesic-MR Tablet.

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Driving

Caution

Novagesic-MR Tablet may cause dizziness or drowsiness. So, do not drive or operate machinery unless you are alert after taking Novagesic-MR Tablet.

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Liver

Caution

Inform your doctor before taking Novagesic-MR Tablet if you have a liver impairment/disorder history. Novagesic-MR Tablet is not recommended for use in patients with severely impaired liver function.

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Kidney

Caution

Inform your doctor before receiving Novagesic-MR Tablet if you have a kidney impairment/disorder history. Novagesic-MR Tablet is not recommended for use in patients with severely impaired kidney function.

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Children

Unsafe

Novagesic-MR Tablet is not recommended for children as safety and effectiveness are not established.

Have a query?

FAQs

Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Novagesic-MR Tablet aids in relieving muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

Diarrhoea might be a side-effect of Novagesic-MR Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Dry mouth could be a side-effect of Novagesic-MR Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Taking Novagesic-MR Tablet can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Novagesic-MR Tablet if you have gastrointestinal bleeding or other bleeding problems before using Novagesic-MR Tablet.

It is not advisable to take Novagesic-MR Tablet and ciprofloxacin simultaneously. Inform your doctor if you are now using or have recently used ciprofloxacin. Your doctor may advise you to take these two medications at different times.

Country of origin

India

Manufacturer/Marketer address

49, First Floor, Railway Link Road, Amritsar-143001, Punjab, India
Other Info - NOVA480

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