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Novagesic-MR Tablet is a combination medicine that contains pain relievers and muscle relaxants. It is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a muscle cramp or feel tight or stiff, like a knot.
Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, Novagesic-MR Tablet helps to reduce muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.
Novagesic-MR Tablet is prescribed medication, and it should be taken as directed by the doctor. In some cases, you may experience common side effects such as vomiting, diarrhoea, headaches, drowsiness and ringing in your ears (tinnitus), fluctuations in blood pressure, dry mouth, stomach upsets, and a decrease or increase in heart rate. Most of these side effects do not require medical attention and will resolve gradually. If any of these effects persist, consult your doctor.
Avoid taking Novagesic-MR Tablet if you are allergic to any of its components. Before taking Novagesic-MR Tablet, tell your doctor about your medical history and other medications you are currently taking to rule out any possible side effects. Novagesic-MR Tablet is not recommended for use in pregnancy. If you are breastfeeding, consult your doctor before taking Novagesic-MR Tablet. This medicine may cause dizziness, so drive only if you are alert and focused. Novagesic-MR Tablet should not be given to children as safety has not been established. Avoid consuming alcohol while on treatment with Novagesic-MR Tablet as it could lead to liver damage.
Novagesic-MR Tablet is used in the treatment of spasticity and associated muscle pain and stiffness. The detailed uses of Novagesic-MR Tablet are as follows:
Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Novagesic-MR Tablet aids in relieving muscle stiffness, spasms, and pain. Besides this, paracetamol reduces elevated temperature by altering the chemical messengers in the brain area that regulates body temperature.
Caution
Avoid consumption of alcohol while taking Novagesic-MR Tablet as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.
Caution
Novagesic-MR Tablet is not recommended for use in pregnant women. If you are pregnant or planning pregnancy, consult your doctor before taking Novagesic-MR Tablet.
Caution
Novagesic-MR Tablet is generally not recommended for use in breastfeeding mothers. If you are breastfeeding, consult your doctor before taking Novagesic-MR Tablet.
Caution
Novagesic-MR Tablet may cause dizziness or drowsiness. So, do not drive or operate machinery unless you are alert after taking Novagesic-MR Tablet.
Caution
Inform your doctor before taking Novagesic-MR Tablet if you have a liver impairment/disorder history. Novagesic-MR Tablet is not recommended for use in patients with severely impaired liver function.
Caution
Inform your doctor before receiving Novagesic-MR Tablet if you have a kidney impairment/disorder history. Novagesic-MR Tablet is not recommended for use in patients with severely impaired kidney function.
Unsafe
Novagesic-MR Tablet is not recommended for children as safety and effectiveness are not established.
Caution
Inform your doctor before taking Novagesic-MR Tablet if you have heart disease. Novagesic-MR Tablet is not recommended for use in patients with severely impaired heart function.
Consult your doctor
Limited information available about the use of Novagesic-MR Tablet in geriatric patients. Please consult your physician.

Have a query?
The time required for Novagesic-MR Tablet to start to work: Novagesic-MR Tablet ideally shows its action within 20 to 30 minutes after administration. The time for which the effects of Novagesic-MR Tablet last: The duration of action for Novagesic-MR Tablet is clinically unknown.
Drug-Drug Interactions: Novagesic-MR Tablet may interact with certain pain killers (e.g. hydrocodone), anti-depressants (e.g. fluvoxamine, escitalopram), antibiotics (e.g. ciprofloxacin), antihypertensives (e.g. metoprolol), anticoagulant (e.g. apixaban), certain painkillers (e.g. celecoxib), and antiretroviral medicine (e.g. tenofovir).
Drug-Food Interactions: Do not drink alcohol while taking Novagesic-MR Tablet.
Drug-Disease Interactions: Novagesic-MR Tablet may interact with various disease conditions that include ulcer or perforation, bleeding problems, hepatotoxicity (liver impairment), hypotension, renal dysfunction or toxicities, asthma, fluid retention, GI toxicity, rash, thrombosis (blood clots).
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Novagesic-MR Tablet is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.
Novagesic-MR Tablet contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Novagesic-MR Tablet aids in relieving muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.
Diarrhoea might be a side effect of Novagesic-MR Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Dry mouth could be a side effect of Novagesic-MR Tablet. To stimulate saliva and prevent dry mouth, individuals can limit caffeine intake, avoid smoking and alcohol-containing mouthwashes, drink water regularly, and chew sugar-free gum or candy.
Taking Novagesic-MR Tablet can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Novagesic-MR Tablet if you have gastrointestinal bleeding or other bleeding problems before using Novagesic-MR Tablet.
Novagesic-MR Tablet may interact with ciprofloxacin and can lead to stomach irritation. Hence, caution should be exercised while taking these medicines. Please inform your doctor if you are taking any antibiotics before taking Novagesic-MR Tablet.
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