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  3. Nostra-CR 15 Tablet 5's

Prescription drug
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Nostra-CR 15 Tablet 5's, Pack of 5 TABLETS
Nostra-CR 15 Tablet 5's, Pack of 5 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nostra-CR 15 Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NORETHISTERONE-15MG

Manufacturer/Marketer :

Corona Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nostra-CR 15 Tablet

Nostra-CR 15 Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis.

Nostra-CR 15 Tablet contains Norethisterone, which mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining.

Common side effects include unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects do not require medical attention. However, if the side effects persist, please consult your doctor.

If you are allergic to Nostra-CR 15 Tablet or any other medicines, please tell your doctor. Nostra-CR 15 Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Nostra-CR 15 Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Nostra-CR 15 Tablet.

Uses of Nostra-CR 15 Tablet

Nostra-CR 15 Tablet is used to treat endometriosis. The detailed uses of Nostra-CR 15 Tablet are as follows:

  • Menstrual Cycle Regulation: Nostra-CR 15 Tablet is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
  • Management of Endometriosis: Nostra-CR 15 Tablet is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
  • Support in Hormone Replacement Therapy: In postmenopausal women, Nostra-CR 15 Tablet is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
  • Relieve Menstrual problems: Nostra-CR 15 Tablet is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

Have a query?

Directions for Use

  • Nostra-CR 15 Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Nostra-CR 15 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Nostra-CR 15 Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone.
  • It restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.
  • Nostra-CR 15 Tablet is also used in the treatment of breast cancer.

How Nostra-CR 15 Tablet Works

Nostra-CR 15 Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nostra-CR 15 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nostra-CR 15 Tablet

Take Nostra-CR 15 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Nostra-CR 15 Tablet or any other medicines, please tell your doctor.
  • Nostra-CR 15 Tablet is not recommended for pregnant women as it may harm an unborn baby.
  • If you are breastfeeding, consult a doctor before taking Nostra-CR 15 Tablet.
  • It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Nostra-CR 15 Tablet.
  • You are advised to stop smoking while taking Nostra-CR 15 Tablet as it may increase the risk of adverse effects.
  • If you are about to undergo any surgery, please inform your doctor that you are taking Nostra-CR 15 Tablet as it may increase the effect of certain anesthetics.
  • If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Nostra-CR 15 Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneFosamprenavir
Severe
NorethisteroneBosentan
Severe

Drug-Drug Interactions

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NorethisteroneFosamprenavir
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Nostra-CR 15 Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Co-administration of Nostra-CR 15 Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Nostra-CR 15 Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteronePrimidone
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Coadministration of Nostra-CR 15 Tablet and primidone can reduce the blood levels and effects of Nostra-CR 15 Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Nostra-CR 15 Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneEslicarbazepine
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Eslicarbazepine may reduce the effects of Nostra-CR 15 Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Nostra-CR 15 Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneDabrafenib
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Coadministration of Nostra-CR 15 Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Nostra-CR 15 Tablet in the body.

How to manage the interaction:
Taking Nostra-CR 15 Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneFelbamate
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Using Felbamate and Nostra-CR 15 Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Nostra-CR 15 Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Nostra-CR 15 Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Using Etretinate and Nostra-CR 15 Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Nostra-CR 15 Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneRifabutin
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Coadministration of Nostra-CR 15 Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Nostra-CR 15 Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Nostra-CR 15 Tablet:
Using Telaprevir and Nostra-CR 15 Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Nostra-CR 15 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-15MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Nostra-CR 15 Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Nostra-CR 15 Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Nostra-CR 15 Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

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Alcohol

Consult your doctor

The interaction of Nostra-CR 15 Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Nostra-CR 15 Tablet.

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Pregnancy

Unsafe

Nostra-CR 15 Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Nostra-CR 15 Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Nostra-CR 15 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Nostra-CR 15 Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Nostra-CR 15 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Nostra-CR 15 Tablet is not recommended for use in children under 18 years.

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Heart

Nostra-CR 15 Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Nostra-CR 15 Tablet.

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Geriatrics

Unsafe

Nostra-CR 15 Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

FAQs

Nostra-CR 15 Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Nostra-CR 15 Tablet may be used in the treatment of breast cancer.

Nostra-CR 15 Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Nostra-CR 15 Tablet may be used to delay periods. Nostra-CR 15 Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Nostra-CR 15 Tablet.

Nostra-CR 15 Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Nostra-CR 15 Tablet.

You are not recommended to take Nostra-CR 15 Tablet with rifampicin as it may decrease the levels of Nostra-CR 15 Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Nostra-CR 15 Tablet with other medicines.

Country of origin

INDIA

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - NOS0101

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:28 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1494.pdf
  2. https://www.drugs.com/mtm/norethindrone.html

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