Nitrocin 0.4 mg Spray 5 ml

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Prescription Medicine

Nitrocin 0.4 mg Spray 5 ml is indicated in preventing attacks of angina (chest pain) and treatment of angina due to coronary artery disease. This medicine is also used to manage acute angina attacks in emergency situations and sometimes in the treatment of heart failure or high blood pressure during surgery.

Written By Lakshmithulasi Yarragunta ,

Reviewed By Santoshini Reddy G , M Pharmacy

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More about the Product

Composition :

GLYCERYL TRINITRATE-0.40MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Sublingual

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nitrocin 0.4 mg Spray 5 ml

Nitrocin 0.4 mg Spray 5 ml is primarily indicated in preventing attacks of angina (chest pain) and treating angina due to coronary artery disease. Angina occurs when the heart does not receive sufficient oxygen.

Nitrocin 0.4 mg Spray 5 ml contains Glyceryl Trinitrate, which relaxes blood vessels and reduces the heart's oxygen demand.

Nitrocin 0.4 mg Spray 5 ml may cause common side effects such as dry mouth, blurred vision, headache, dizziness, weakness, nausea and vomiting, sweating, paleness, fainting, and flushing (warm or red skin). Most of these side effects are temporary and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You should not take Nitrocin 0.4 mg Spray 5 ml if you are allergic to nitrates or any of its ingredients or are taking medication for hypertension, glaucoma, heart disease, erectile dysfunction, or anaemia. Check with your doctor if you're pregnant, currently breastfeeding or taking any other prescribed or non-prescribed medicines.

Uses of Nitrocin 0.4 mg Spray 5 ml

Nitrocin 0.4 mg Spray 5 ml is used in the treatment of heart-related chest pain (angina). The detailed uses of Nitrocin 0.4 mg Spray 5 ml are as follows:

Angina Pectoris Relief: Nitrocin 0.4 mg Spray 5 ml is effective in preventing chest pain (angina) by enhancing blood flow to the heart muscle.
Treatment of coronary artery disease symptoms: Improves blood flow in patients with narrowed heart arteries.

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Directions for Use

The recommended dose is 1-2 sprays at the onset of an attack or as advised by your doctor.
Sit down and hold the canister upright, aiming the spray under the tongue.
Close your mouth immediately after using the spray. Do not inhale the spray.
After using the spray, rest for a while. When you stand up, rise slowly, as you may feel faint.

Key Benefits

Provides fast relief from chest pain caused by reduced blood flow to the heart.
Relaxes and widens blood vessels, allowing better circulation to the heart.
Decreases the pressure on the heart, making it easier for the heart to pump blood.
Can be used before physical activity to help prevent chest pain episodes.
Sublingual tablets work quickly because they are absorbed directly under the tongue.

How Nitrocin 0.4 mg Spray 5 ml Works

Nitrocin 0.4 mg Spray 5 ml contains Glyceryl Trinitrate, which is a vasodilator in nature. It works by relaxing the blood vessels and decreasing the heart's demand for oxygen. As a result, it reduces heart workload and prevents attacks of angina.

Storage

Store in a cool and dry place away from sunlight

Side effects of Nitrocin 0.4 mg Spray 5 ml

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Nitrocin 0.4 mg Spray 5 ml

Do not use more than the prescribed dose of Nitrocin 0.4 mg Spray 5 ml as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not use Nitrocin 0.4 mg Spray 5 ml if you are allergic to any of its ingredients.
Inform your doctor about all other OTC medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
Let the doctor know if you have severe low blood pressure, shock caused by low blood pressure, severe anaemia, heart problems, low heart rate, brain problems, glaucoma, an underactive thyroid, liver or kidney problems.
Consult the doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

Glyceryl trinitrateVardenafil

Critical

Glyceryl trinitrateAvanafil

Critical

Drug-Drug Interactions

Glyceryl trinitrateVardenafil

Critical

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Taking Vardenafil and Nitrocin 0.4 mg Spray 5 ml together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Vardenafil and Nitrocin 0.4 mg Spray 5 ml is generally avoided as it can lead to an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Glyceryl trinitrateAvanafil

Critical

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Taking Avanafil and Nitrocin 0.4 mg Spray 5 ml together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Avanafil and Nitrocin 0.4 mg Spray 5 ml is generally avoided as it can lead to an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Glyceryl trinitrateMethylergometrine

Critical

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Methylergometrine with Nitrocin 0.4 mg Spray 5 ml can increase the levels and side effects of Methylergometrine.

How to manage the interaction:
Taking Methylergometrine with Nitrocin 0.4 mg Spray 5 ml is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.

Glyceryl trinitrateEtidocaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Etidocaine and Nitrocin 0.4 mg Spray 5 ml can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Etidocaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.

Glyceryl trinitrateTetracaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Tetracaine and Nitrocin 0.4 mg Spray 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Tetracaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Glyceryl trinitrateProcaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Procaine and Nitrocin 0.4 mg Spray 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking procaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Glyceryl trinitratePrilocaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Prilocaine and Nitrocin 0.4 mg Spray 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking prilocaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Glyceryl trinitrateLevobupivacaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Levobupivacaine and Nitrocin 0.4 mg Spray 5 ml can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Levobupivacaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.

Glyceryl trinitrateMepivacaine

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Mepivacaine and Nitrocin 0.4 mg Spray 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Mepivacaine and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.

Glyceryl trinitrateSodium nitrite

Severe

How does the drug interact with Nitrocin 0.4 mg Spray 5 ml:
Coadministration of Sodium nitrite and Nitrocin 0.4 mg Spray 5 ml has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Sodium nitrite and Nitrocin 0.4 mg Spray 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Diet

Eat a heart-healthy diet with plenty of fruits, vegetables, and whole grains.
Reduce salt intake to help control blood pressure and protect heart health.
Limit fatty and fried foods to maintain healthy cholesterol levels.

Lifestyle changes

Do moderate exercises such as walking or light stretching to maintain heart health.
Avoid heavy physical exertion that may trigger chest pain or angina.
Rest immediately if chest pain occurs and use the sublingual tablet as prescribed.
Consult your doctor before starting new exercises, especially if you have heart disease.

Stress management

Practice relaxation techniques such as deep breathing or meditation to reduce stress.
Maintain regular sleep habits to support heart health and reduce anxiety.
Avoid emotional stress and overexertion, as they may trigger angina (chest pain).

Habits

Avoid excessive alcohol and smoking, as it may increase dizziness and lower blood pressure.

Habit Forming

Therapeutic Class

[ANTIANGINALS]

Alcohol

Unsafe

Concomitant use of Nitrocin 0.4 mg Spray 5 ml and alcohol may increase side effects. So, the intake of alcohol should be avoided with Nitrocin 0.4 mg Spray 5 ml.

Pregnancy

Consult your doctor

Nitrocin 0.4 mg Spray 5 ml is a pregnancy Category C medicine. Please consult the doctor if you are pregnant or planning to become pregnant.

Breast Feeding

Consult your doctor

The safety of Nitrocin 0.4 mg Spray 5 ml is unknown during breastfeeding. Please consult the doctor if you are breastfeeding.

Driving

Caution

Nitrocin 0.4 mg Spray 5 ml may cause dizziness and lightheadedness. Therefore, driving or operating machinery that requires concentration should be avoided until this feeling subsides.

Liver

Consult your doctor

Consult the doctor before using Nitrocin 0.4 mg Spray 5 ml if you have liver disease.

Kidney

Consult your doctor

Consult the doctor before using Nitrocin 0.4 mg Spray 5 ml if you have kidney disease.

Children

Unsafe

The safety and efficacy of Nitrocin 0.4 mg Spray 5 ml in children have not been established. Nitrocin 0.4 mg Spray 5 ml is not recommended for children.

Heart

Consult your doctor

Let your doctor know if you have heart disease before using Nitrocin 0.4 mg Spray 5 ml. Your doctor will prescribe only if the benefits outweigh the risks.

Geriatrics

Consult your doctor

Nitrocin 0.4 mg Spray 5 ml can be used in elderly patients with proper monitoring and individualised care. If you have any concerns about using Nitrocin 0.4 mg Spray 5 ml, please consult a doctor.

FAQs

What is the use of Nitrocin 0.4 mg Spray 5 ml?

Nitrocin 0.4 mg Spray 5 ml is used in preventing attacks of angina (chest pain).

How does Nitrocin 0.4 mg Spray 5 ml work?

Nitrocin 0.4 mg Spray 5 ml contains Glyceryl Trinitrate, which relaxes blood vessels and reduces the heart's oxygen demand. As a result, it reduces the heart's workload and prevents angina attacks.

Can Nitrocin 0.4 mg Spray 5 ml cause headache?

Yes, Nitrocin 0.4 mg Spray 5 ml may cause a headache as a side effect. Consult the doctor if the headache persists or worsens.

I have severe anemia, can I use Nitrocin 0.4 mg Spray 5 ml?

It is advised to consult the doctor before using Nitrocin 0.4 mg Spray 5 ml if you have severe anaemia (low levels of iron in blood), as it may not be recommended in such cases.

Can I use Nitrocin 0.4 mg Spray 5 ml in more than the recommended dose to recover from symptoms quickly?

Avoid exceeding the recommended dose. Use Nitrocin 0.4 mg Spray 5 ml only as advised by the doctor. If your angina is not relieved even after 5 minutes of using the first dose, you may use a second spray. Seek immediate medical attention if the pain persists for 15 minutes or longer, despite using the spray.

What are the side effects of Nitrocin 0.4 mg Spray 5 ml?

Side effects of Nitrocin 0.4 mg Spray 5 ml include headache, dizziness, lightheadedness, faintness upon standing, and changes in heartbeat. Most of these side effects of Nitrocin 0.4 mg Spray 5 ml may not require medical attention and will gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Other Info - NIT0056

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Author Details

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Mar 12, 2026 | 12:13 PM IST

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