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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Nirflox Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria by inhibiting the gyrase enzyme and thereby helps reduce various bacterial infections of urinary tract, genital tract, chest, lungs, skin, and soft tissue. This medicine is not effective for treating viral infections. Common side effects include constipation, nausea, diarrhoea, headache, dizziness, light-headedness, pain, redness, and injection site reactions.
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Whats That

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Composition :

OFLOXACIN-200MG

Manufacturer/Marketer :

Nirlife Healthcare

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nirflox Injection

Nirflox Injection is used in the treatment of bacterial infections of the urinary tract, genital tract, chest, lungs, skin, and soft tissue. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Nirflox Injection does not work against infections caused by a virus.

Nirflox Injection contains Ofloxacin, which works by interfering with bacterial enzymes and DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Nirflox Injection kills bacteria and clears the infection. 

Nirflox Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience redness, swelling or pain at the injection site, headache, nausea, and diarrhoea. Most of these side effects of Nirflox Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Nirflox Injection . Avoid taking Nirflox Injection and consult a doctor if you are breastfeeding as Nirflox Injection may be excreted in human milk and cause adverse effects in the baby. Nirflox Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert, as Nirflox Injection may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with Nirflox Injection as it may cause sleepiness or dizziness.

Uses of Nirflox Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Nirflox Injection will be administered by the doctor.• Do not self-administer.

Medicinal Benefits

Nirflox Injection contains Ofloxacin, a broad-spectrum antibiotic that acts against both gram-negative and gram-positive bacteria. Nirflox Injection is used to treat several bacterial infections. It interferes with the bacterial enzyme involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Nirflox Injection kills bacteria and clears the infection. 

How Nirflox Injection Works

Nirflox Injection contains Ofloxacin, which works by interfering with bacterial enzymes and DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Nirflox Injection kills bacteria and clears the infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nirflox Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nirflox Injection

Nirflox Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include severe dizziness. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Nirflox Injection . Avoid taking Nirflox Injection and consult a doctor if you are breastfeeding as Nirflox Injection may be excreted in human milk and cause adverse effects in the baby. Nirflox Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert as Nirflox Injection may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with Nirflox Injection as it may cause sleepiness or dizziness. If you have low levels of magnesium or potassium in your blood, inform your doctor before taking Nirflox Injection . If you have received transplantation or are about to undergo an operation under general anaesthesia, inform your doctor before taking Nirflox Injection .

Drug-Drug Interactions

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OfloxacinSaquinavir
Critical

Drug-Drug Interactions

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How does the drug interact with Nirflox Injection 100 ml:
The combination of Amiodarone and Nirflox Injection 100 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Nirflox Injection 100 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Nirflox Injection 100 ml:
Using halofantrine together with Nirflox Injection 100 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Nirflox Injection 100 ml:
Using bepridil together with Nirflox Injection 100 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Nirflox Injection 100 ml:
Using Mesoridazine together with Nirflox Injection 100 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Nirflox Injection 100 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
How does the drug interact with Nirflox Injection 100 ml:
Coadministration of Nirflox Injection 100 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nirflox Injection 100 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Nirflox Injection to restore healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria in the intestine. 

  • Include fibre-rich foods, as they can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains such as whole grain bread and, brown rice should be included in your diet. 

  • Make sure you drink plenty of water or other fluids every day while you are taking Nirflox Injection .

  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid alcohol consumption with Nirflox Injection as it may cause dizziness or sleepiness. Please consult a doctor before consuming alcohol while using Nirflox Injection .

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Nirflox Injection is given to pregnant women only if doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Nirflox Injection may be excreted in human milk. Therefore, Nirflox Injection is not recommended for breastfeeding mothers. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Nirflox Injection may cause dizziness, drowsiness or changes in vision. Therefore, drive only if you are alert after taking Nirflox Injection .

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Liver

Caution

Take Nirflox Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Nirflox Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Nirflox Injection is not recommended for children below 18 years of age as the safety and effectiveness were not established.

Have a query?

FAQs

Nirflox Injection is used in the treatment of bacterial infections of the urinary tract, genital tract, chest, lungs, skin, and soft tissue.

Nirflox Injection works by interfering with bacterial enzyme, DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Nirflox Injection kills bacteria and clears the infection.

Nirflox Injection may be used to treat lung infections caused by bacteria. Nirflox Injection is an antibiotic that kills bacteria and prevents the spread of infection.

You are not recommended to take Nirflox Injection with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult your doctor before taking Nirflox Injection with other medicines.

Nirflox Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, consult a doctor immediately.

Nirflox Injection is not used to treat viral infections. Nirflox Injection is an antibiotic which is used to treat only bacterial infections.

Country of origin

INDIA

Manufacturer/Marketer address

5Th Floor, Commerce House 5, Near Vodafone Office, Behind Ymca Club, Prahaladnagar Road, Ahmedabad-380051
Other Info - NIR0001

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