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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Niresulide PM Syrup is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain. It contains Nimesulide and Paracetamol, which works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Thus, it helps relieve pain. It may cause common side effects such as loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine.

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Manufacturer/Marketer :

Nirlife Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Niresulide PM Syrup

Niresulide PM Syrup belongs to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain. 

Niresulide PM Syrup is composed of two medicines: Nimesulide and Paracetamol. Niresulide PM Syrup works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Niresulide PM Syrup helps relieve pain.

Take Niresulide PM Syrup exactly as directed by your doctor. The most common side effects of Niresulide PM Syrup are loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine. It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.

Do not take Niresulide PM Syrup if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Niresulide PM Syrup may be associated with a small increase in heart attack risk (myocardial infarction). Avoid alcohol consumption as it may damage your liver and cause increased side effects on taking this medicine. Consult your doctor if your pain, inflammation and fever symptoms do not disappear even after ten days.

Uses of Niresulide PM Syrup

Niresulide PM Syrup is used to provide pain relief. The detailed uses of Niresulide PM Syrup are as follows:

  • Pain Relief: Niresulide PM Syrup relieves mild to moderate pain, such as headaches, muscle aches, and joint pain.
  • Fever Reduction: Niresulide PM Syrup helps to reduce fever, relieving discomfort caused by high body temperature.
  • Arthritis Management: Niresulide PM Syrup is involved in managing arthritis symptoms by reducing pain and inflammation.
  • Post-operative Care: Niresulide PM Syrup helps to manage post-operative pain, making recovery more comfortable after surgery.
  • Chronic Pain Conditions: Niresulide PM Syrup provides relief for chronic pain conditions, helping when other treatments may not be enough.
  • Respiratory Infection Relief: Niresulide PM Syrup is also used to alleviate pain, fever, and inflammation associated with respiratory infection.

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Directions for Use

  • Niresulide PM Syrup should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Niresulide PM Syrup as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Niresulide PM Syrup comprises nimesulide and paracetamol, primarily used to treat mild to moderate pain. Niresulide PM Syrup is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps treat pain by blocking the chemical messenger in the brain responsible for causing fever, pain and inflammation. Nimesulide works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting prostaglandin synthesis by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.

How Niresulide PM Syrup Works

Niresulide PM Syrup is composed of two medicines: Nimesulide and Paracetamol. Niresulide PM Syrup works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Niresulide PM Syrup helps relieve pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Niresulide PM Syrup

Do not take more than the prescribed dose of Niresulide PM Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Niresulide PM Syrup is contraindicated in patients with a history of hypersensitivity (allergic) reaction to Niresulide PM Syrup, paracetamol, nimesulide, or other pain killers. Please inform your doctor before starting Niresulide PM Syrup if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery or severe kidney/liver impairment. Nimesulide present in Niresulide PM Syrup is known to affect fertility, so if you are planning for pregnancy, contact the doctor. Niresulide PM Syrup should be avoided in both pregnant (especially last trimester of pregnancy) and breastfeeding women, as it may pass the milk affecting the baby. Patients with heart diseases and recent stroke (bleeding in the brain) should not take Niresulide PM Syrup as a substitute for aspirin. It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching low,, impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In chronic arthritis or joint pain conditions, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize chemical cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

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Alcohol

Caution

Taking Niresulide PM Syrup with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with Niresulide PM Syrup.

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Pregnancy

Unsafe

Use of Niresulide PM Syrup during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Use of Niresulide PM Syrup during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.

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Driving

Caution

After taking Niresulide PM Syrup, you may notice dizziness, sleepiness, drowsiness. So, you should stop taking Niresulide PM Syrup and contact your doctor.

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Liver

Caution

Niresulide PM Syrup to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Niresulide PM Syrup to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Niresulide PM Syrup is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

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Heart

Niresulide PM Syrup should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Niresulide PM Syrup should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using Niresulide PM Syrup, please consult a doctor.

FAQs

Niresulide PM Syrup is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.

Niresulide PM Syrup works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Niresulide PM Syrup helps relieve pain.

No, Niresulide PM Syrup is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of stomach ulcer or gastric bleeding. Do not take Niresulide PM Syrup in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.

No, Niresulide PM Syrup should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results, take it in the doses and duration advised by your doctor.

Yes, Niresulide PM Syrup should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and an upset stomach.

Country of origin

India
Other Info - NIRE236

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