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  3. Nioclean Gel 20 gm

Nioclean Gel 20 gm, Pack of 1 GEL
Nioclean Gel 20 gm, Pack of 1 GEL
Nioclean Gel 20 gm, Pack of 1 GEL
Nioclean Gel 20 gm, Pack of 1 GEL
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nioclean Gel is used to treat inflamed acne. It minimises the formation of excessive natural oil, known as sebum. It also reduces swelling caused by acne. It contains Clindamycin and Nicotinamide, which penetrate the skin and help kill acne-causing bacteria. Also, it helps reduce swelling, redness, and tenderness caused by acne or pimples. Besides this, it also prevents the formation of pimples, blackheads and whiteheads on the skin. In some cases, you may experience side effects such as irritation, dryness, peeling, redness and burning sensation at the application site. It is advised to use a skin moisturiser and drink plenty of water to prevent side effects.

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Composition :

CLINDAMYCIN-1%W/W + NICOTINAMIDE-4%W/W

Manufacturer/Marketer :

Klm Laboratories Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Nioclean Gel

Nioclean Gel is primarily used to treat inflamed acne. Acne is a skin condition in which the oil glands (sebaceous glands) of the skin become clogged, forming pimples and sometimes cysts. It minimizes the formation of excessive natural oil, known as sebum.

Nioclean Gel is composed of Clindamycin and Nicotinamide. Clindamycin helps kill bacteria that cause acne. Nicotinamide, which is responsible for exerting anti-inflammatory effects that are applied to the skin.

In some cases, you may experience irritation, dryness, peeling, redness and a burning sensation at the application site. Most of the side effects of Nioclean Gel do not require medical attention and usually resolve on their own. However, if the side effects persist, reach out to your doctor.

Nioclean Gel is meant for external use only. It should be applied in a sufficient quantity to cover the affected area. Wash your hands before and after using this medicine. If it accidentally comes into contact with your eyes, nose, mouth, or any other sensitive area, immediately rinse it with water.

Do not stop using this medicine without consulting your doctor. Inform your doctor if you are pregnant or breastfeeding. Also, if you are allergic to this medicine, please let your doctor know.

Uses of Nioclean Gel

Nioclean Gel is used in the treatment of acne. The detailed uses of Nioclean Gel are as follows:

  • Acne Treatment: Nioclean Gel is frequently used to treat acne by reducing skin bacteria and irritation, which helps prevent new outbreaks.
  • Bacterial Infections: Due to its antibacterial properties, it is effective in treating localised bacterial skin infections.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Nioclean Gel should be applied to the entire affected area rather than just to acne or pimples. Applying to the entire skin will help prevent the new pimples from erupting.
  • Nioclean Gel is only for external use. 
  • Do not apply Nioclean Gel to the broken skin or wounds.

Medicinal Benefits

  • Nioclean Gel contains Clindamycin and Nicotinamide (Vitamin B3).
  • Clindamycin is a well-known bacteriostatic antibiotic that treats acne, bacterial infections, and scars, and is suitable for both dry and oily skin.
  • It helps in the healing of acne by killing the bacteria that cause acne and preventing further bacterial skin infections.
  • Nicotinamide is a synthetic form of Vitamin B3 that stimulates ceramide (fats found in the uppermost layer of the skin) synthesis and improves the epidermal permeability barrier function, making the skin look supple and soft.

How Nioclean Gel Works

Nioclean Gel is composed of two medicines namely: Clindamycin and Nicotinamide. Clindamycin is a lincomycin antibiotic that penetrates the skin and helps kill bacteria that cause acne. On the other hand, Nicotinamide is a form of vitamin B that is responsible for exerting anti-inflammatory effects when applied to the skin. Together, they help reduce swelling, redness, and tenderness caused by acne or pimples. Besides this, it also prevents the formation of pimples, blackheads, and whiteheads on the skin.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nioclean Gel 20 gm
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
  • Avoid hot or cold temperatures, and shower with lukewarm water.
  • Apply sunscreen with an SPF of at least 30 every day, even in winter.
  • Limit spicy foods and other foods that can cause redness.
  • Limit alcohol consumption, especially red wine.
  • Avoid clothing made from wool and other irritating fabrics.
  • Don't exfoliate too much, and use gentle scrubs.
  • Avoid products with menthol, camphor, or sodium lauryl sulfate.
  • Identify and avoid allergens that can cause allergic reactions.
  • Use a gentle, non-drying cleanser and moisturizer that are suitable for your skin type.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Nioclean Gel

Do not apply Nioclean Gel in large amounts or use it for a longer time than recommended, as it does not give quick or better results but increases the risk of side effects.

Drug Warnings

  • Do not take Nioclean Gel if you are allergic to any of its ingredients.
  • Nioclean Gel is meant for topical use only and not for oral, ophthalmic or intravaginal use.
  • You should not use a Nioclean Gel if your skin is very sensitive or allergic to Nioclean Gel or the lincomycin class of antibiotics.
  • Do not apply Nioclean Gel on the cut, scraped, sunburned or eczema-affected skin part.
  • If Nioclean Gel gets into your eyes accidentally, rinse your eyes thoroughly with water and contact your doctor immediately if the irritation persists.
  • Inform your doctor if your skin conditions do not improve. It may take time to treat acne, so do not apply a dosage more than prescribed for better and faster results.
  • If you are pregnant, planning for pregnancy or a nursing mother, consult your doctor before using Nioclean Gel.
  • Consult a doctor if you are using dermatological products other than Nioclean Gel, as it may lead to unfavourable results, such as excessive skin drying, peeling, or irritation.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid fried and oily foods, and drink plenty of water.
  • It is advised to avoid unnecessary exposure to the sun.
  • In case, it is necessary to go out in the sun, use sunscreen.
  • Do not itch or scratch the infected area.
  • Use moisturiser to prevent the occurrence of side effects.
  • Exercise regularly to reduce stress.

Habit Forming

No

Therapeutic Class

TOPICAL ANTIBIOTICS

Nioclean Gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Safe if prescribed

There are no interactions found with Nioclean Gel pertaining to alcohol. However, it is advised to avoid alcohol for a speedy recovery.

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Pregnancy

Consult your doctor

There are no well-established clinical studies with Nioclean Gel in pregnant women. Hence, Nioclean Gel should be used during pregnancy only if clearly needed. Consult your doctor before taking this medicine.

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Breast Feeding

Safe if prescribed

Nioclean Gel is safe to use in breastfeeding. However, please inform your doctor that you are breastfeeding if you are prescribed Nioclean Gel.

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Driving

Safe if prescribed

There are no effects found of Nioclean Gel on driving capabilities.

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Liver

Consult your doctor

Please inform your doctor if you are suffering from or have suffered from liver disease.

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Kidney

Consult your doctor

Please inform your doctor if you are suffering from or have suffered from kidney disease.

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Children

Unsafe

Nioclean Gel should be used in children only if prescribed by a specialist. The safety and effectiveness of Nioclean Gel have not been established in children below 12 years of age.

Have a query?

FAQs

Nioclean Gel is used to treat acne. It works by killing the acne-causing bacteria and reducing the swelling, redness and tenderness caused by acne or pimples.

The precautions to take when using Nioclean Gel are to avoid showering or bathing for at least 1 hour after application. Avoid contact of Nioclean Gel with eyes and mucous membranes. Other topical products, such as cosmetics, lotions, insect repellents, moisturisers, or other topical medications, should be avoided. Avoid unnecessary exposure to the sun, and if you have to go out in the sun, apply sunscreen.

Nioclean Gel may take up to 2-3 weeks to show its effect. Use it as directed by your doctor. If symptoms do not improve, please consult your doctor.

The side effects of Nioclean Gel include peeling, dryness, irritation, redness and burning sensation at the application site. If these side effects persist or worsen, please consult your doctor.

No, do not overuse Nioclean Gel, as it can cause severe diarrhoea due to the medicine being absorbed too quickly into the body. If your symptoms become more severe, please consult your doctor.

Store Nioclean Gel in a cool and dry place. Keep it out of children's reach. Dispose of the unused medicine.

Nioclean Gel should not be used to treat a single pimple, as it is not a spot treatment. Apply Nioclean Gel to the entire face. Use it once a day to help treat your acne.

It may take 2-3 weeks for your symptoms to improve, and it may take some time for you to see significant results. Use Nioclean Gel as directed and let your doctor know if your symptoms do not improve or get worse.

Yes, Nioclean Gel is very useful in controlling pimples and also helps lighten the aftermarks.

Yes, Nioclean Gel can be used every day in the doses prescribed by your doctor until your skin problem improves. Please avoid using it for an extended period on your skin.

Country of origin

India

Manufacturer/Marketer address

KLM LABORATORIES PVT LTD, 1004, Hubtown Viva, Jogeshwari (E), Mumbai-400060, Maharashtra, India.
Other Info - NIO0004

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 26, 2025 | 5:22 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8e76c7c7-04fd-47c9-8db9-6f74ceffe144
  2. https://www.medicines.org.uk/emc/product/6765/pil

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