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compositionComposition:NIMODIPINE-50MG
prescription
Prescription Medicine
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Nimozen Infusion is used to prevent brain damage due to subarachnoid haemorrhage. It contains Nimodipine, which relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps increase blood flow and circulation, reduce blood pressure, and lower the risk of damage caused by insufficient blood flow to the brain after bleeding.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NIMODIPINE-50MG

Manufacturer/Marketer :

Wohltat Life Sciences

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nimozen Infusion

Nimozen Infusion is given to patients who have had bleeding in the space around the brain, a condition known as a subarachnoid haemorrhage. Its main medical purpose is to prevent serious brain injury caused by a lack of blood flow to vital tissues. By keeping blood flowing properly, it helps protect brain cells from damage after a bleed.

This medicine is given continuously or at regular intervals by healthcare professionals in a hospital, ensuring a steady level in your system. Because it is given directly into a vein, it does not depend on food or digestive health. To support your recovery, resting in a quiet, low-stress environment and avoiding physical strain are highly recommended.

While receiving this medicine, you may experience mild side effects like headaches or low blood pressure. However, you must tell your medical team right away if you experience severe dizziness, chest pain, or a very slow heart rate.

Do not take this if you are allergic to any of its ingredients. Before treatment begins, tell your doctor if you have severe liver damage, heart failure, or naturally low blood pressure.

This medicine can interact with other blood pressure drugs, alcohol, and smoking, which can dangerously lower blood pressure or stress your blood vessels. Pregnant, breastfeeding, or elderly individuals must consult their doctor to weigh the risks and benefits of this treatment.

Uses of Nimozen Infusion

Nimozen Infusion is used to prevent serious brain injury caused by a lack of blood flow to vital tissues. The detailed uses of Nimozen Infusion are as follows:

  • Bleeding around the brain (subarachnoid haemorrhage): Nimozen Infusion helps by preventing the narrowing of blood vessels in the brain, ensuring oxygen-rich blood keeps reaching brain tissue after a bleed.

Key Benefits

Nimozen Infusion offers crucial support during the recovery period following a brain bleed. By keeping blood vessels relaxed, it lowers the risk of secondary brain injury and stroke, helping you recover more safely.

  • Reduces risk of disability: It helps preserve brain function, giving you a better chance of recovering your normal daily abilities.
  • Protects brain tissue: It keeps vital parts of the brain supplied with oxygen, preventing permanent cellular damage during recovery.

Directions for Use

  • Nimozen Infusion is administered only by a healthcare professional, typically through a slow intravenous infusion.
  • Dosage and duration are determined by the doctor based on the patient's condition and response to treatment.
  • Do not self-administer this medication.
  • Improper use can lead to serious side effects, including dangerously low blood pressure.
  • Patients are closely monitored during treatment for vital signs and neurological status to ensure safety and effectiveness.

How Nimozen Infusion Works

Nimozen Infusion contains nimodipine, which belongs to a group of medicines called calcium channel blockers. When a blood vessel in the brain bursts, the body's natural response can cause nearby blood vessels to narrow or spasm, cutting off blood flow. This medicine works by blocking calcium from entering the muscle cells in these blood vessel walls. By blocking this calcium, the medicine allows the blood vessels to relax and widen. This action keeps blood flowing smoothly to your brain cells, preventing the oxygen starvation that causes serious brain damage.
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Alcohol

Consult your doctor

It is not known whether alcohol affects Nimozen Infusion. Please consult your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant. Your doctor will weigh the benefits and the risks before prescribing Nimozen Infusion in pregnancy.

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Breast Feeding

Unsafe

Nimozen Infusion is not recommended during breastfeeding. However, if it is prescribed by your doctor, avoid breastfeeding while on treatment with Nimozen Infusion.

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Driving

Caution

Nimozen Infusion may cause dizziness. Drive and operate machinery only if you are alert.

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Liver

Caution

If you have liver disease, please inform your doctor before receiving Nimozen Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney disease, please inform your doctor before receiving Nimozen Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Nimozen Infusion is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Caution

Nimozen Infusion should be used with caution in patients with heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Consult your doctor

Limited information available about the use of Nimozen Infusion in geriatric patients. Please consult your physician.

What if I have taken an overdose of Nimozen Infusion

Because you will be closely monitored in a hospital, an overdose is rare. If an overdose does occur, it can cause very low blood pressure, a slow or rapid heart rate, or severe nausea. The medical team is trained to handle this and will treat any symptoms right away.

Diet & Lifestyle Advise

  • Stay hydrated: Ensure you receive adequate fluids as directed by your medical team to help maintain stable blood pressure.
  • Avoid alcohol and smoking: These can place extra stress on your blood vessels and interfere with your brain's recovery process.
  • Rest in a quiet environment: Keep your surroundings calm, low-stress, and dim to allow your brain to heal with minimal stimulation.
  • Limit salt intake: Follow any specific dietary recommendations from your doctor to keep your blood pressure within a safe range.
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How Soon It Starts Working

The time required for Nimozen Infusion to start to work: The exact onset time of Nimozen Infusion has not been clinically established. The time for which the effects of Nimozen Infusion last: The duration of Nimozen Infusion’s effect is clinically not established.

What if you forget to take Nimozen Infusion

Since this medicine is given by healthcare professionals in a controlled hospital setting, it is highly unlikely that you will miss a dose. If you think the infusion has been interrupted or delayed, notify your nurse or doctor immediately.

Storage

• This medicine must be stored at room temperature, between 15°C and 30°C.

Drug Warnings

  • Always inspect the liquid before it is given; it must be clear and free of any floating particles or discolouration.
  • This medicine must only be injected into a vein and should never be given in any other way, such as into a muscle or under the skin.
  • Do not suddenly sit up or stand up during or shortly after the infusion, as this can cause a rapid drop in blood pressure and make you faint.
  • Tell your nurse immediately if you feel any burning, pain, or swelling around the injection site.
  • Ensure the medical team is aware of all other medicines you are receiving to prevent dangerous interactions in the IV line.

Drug-Drug Interactions

verifiedApollotooltip

  • Other blood pressure-lowering drugs: Combining these with Nimozen Infusion can cause your blood pressure to drop dangerously low.
  • Liver enzyme inhibitors or inducers: Certain antibiotics, seizure medicines, or antivirals can change how your body processes this medicine, leading to side effects or reduced effectiveness.
NimodipineClarithromycin
Critical
NimodipineRitonavir
Critical

Drug-Drug Interactions

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NimodipineClarithromycin
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Clarithromycin, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clarithromycin and Nimozen Infusion 50 ml is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
NimodipineRitonavir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
Taking Nimozen Infusion 50 ml with Ritonavir can increase the blood levels of ritonavir, which may lead to increased side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and lightheadedness, contact a doctor. Do not discontinue any medications without consulting a doctor.
NimodipineCarbamazepine
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Carbamazepine, it may decrease the blood levels of Nimozen Infusion 50 ml, which may make Nimozen Infusion 50 ml less effective in treating your condition.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Carbamazepine is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
NimodipineTelaprevir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Telaprevir is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Telaprevir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without a doctor's advice.
NimodipineCobicistat
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Cobicistat, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Cobicistat is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without consulting the doctor.
NimodipineTelithromycin
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Telithromycin, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Telithromycin is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure.
NimodipineIndinavir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Indinavir, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Indinavir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling. Do not discontinue any medications without a doctor's advice.
NimodipineAtazanavir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Atazanavir is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Atazanavir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without a doctor's advice.
NimodipineMibefradil
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Mibefradil is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Mibefradil is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without consulting the doctor.
NimodipinePhenobarbital
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Phenobarbital, it may decrease the blood levels of Nimozen Infusion 50 ml, which may make Nimozen Infusion 50 ml less effective in treating the condition.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Phenobarbital is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience any unusual symptoms while taking the therapy. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Grapefruit stops your liver from breaking down this medicine properly, which can increase the drug levels in your body and cause severe side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CALCIUM CHANNEL BLOCKERS]

FAQs

Nimozen Infusion is used to prevent brain damage due to subarachnoid haemorrhage.
Nimozen Infusion relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.
Nimozen Infusion might impair sperm function. So, talk to your doctor if you are trying to father a child or if you have any concerns regarding this.
Diarrhoea could be a side effect of Nimozen Infusion. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Consult your doctor before taking anti-hypertensive medicines whilst on treatment with Nimozen Infusion as it may increase the blood pressure lowering effect of concomitantly used anti-hypertensive medicines. Regular monitoring of blood pressure levels is advised.
Nimozen Infusion may cause constipation in some cases. However, it is not necessary for everyone taking Nimozen Infusion to experience this side effect. If the condition persists or worsens, consult a doctor.
Nimozen Infusion contains Nimodipine which belongs to the group of medicines called calcium channel blockers used to prevent brain damage due to subarachnoid haemorrhage.
Avoid grapefruit and its juice during treatment with Nimozen Infusion as it might increase the blood levels of the medicine. Do not drive or operate machinery as it may cause dizziness.
Nimozen Infusion is administered as a continuous IV infusion by a healthcare professional; do not self-administer.
Nimozen Infusion should not be taken along with the tablet form of nimodipine. However, if needed your doctor may ask you to switch to the tablet form of nimodipine after completion of treatment with Nimozen Infusion.
Nimozen Infusion may cause side effects such as low blood pressure, vasodilation, nausea, constipation, flatulence, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
This medicine is given as a slow injection or continuous infusion directly into a vein by a trained healthcare professional. Talk to your doctor.
No, this medicine is typically given only in a hospital or specialised clinic where healthcare professionals can monitor your blood pressure and heart rate closely. Talk to your doctor.
Dizziness can happen if your blood pressure drops. Tell your doctor or nurse immediately so they can check your vital signs. Talk to your doctor.
This medicine is only given to pregnant women if the potential benefits outweigh the risks to the unborn baby. Talk to your doctor.
Yes, it can interact with other blood pressure medicines and drugs processed by the liver. Always tell your healthcare team about all the medicines you are taking. Talk to your doctor or pharmacist.
Grapefruit contains substances that slow down how your liver breaks down this medicine, which can raise the drug levels in your body to unsafe levels. Talk to your doctor or pharmacist.
The duration of treatment depends on your specific recovery process and is determined by your doctor, usually lasting for up to several weeks after the initial brain bleed. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sco308, First Floor, Sec 38 d Chandigarh, Chandigarh - 160001
Other Info - NIM0427
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