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  3. Nidaglan Vaginal gel

Nidaglan Vaginal gel, Pack of 1 Gel
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Nidaglan Vaginal gel is a female hormone used in the treatment of female infertility. This medicine helps boost the production of hormones involved in the ovulation process. Common side effects include flushing (reddening of the skin, especially the face), headache, Insomnia, tiredness, dizziness, breast pain or tenderness, heavy periods, etc. It is also used to restore the menstrual cycle in women who have missed their periods. This medicine is only intended for use in women. Hence should not be used in male population, pregnant/breastfeeding women, and children.

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Composition :

PROGESTERONE-8%W/W

Manufacturer/Marketer :

Gland Pharma Ltd

Consume Type :

VAGINAL

Return Policy :

Not Returnable

Expires on or after :

About Nidaglan Vaginal gel

Nidaglan Vaginal gel is used to treat female infertility and to aid pregnancy. Female infertility is a condition in which a female body is unable to conceive despite regular, unprotected sexual intercourse for at least one year.

Nidaglan Vaginal gel contains progesterone, a female hormone that regulates ovulation and menstruation in women. 

In some cases, Nidaglan Vaginal gel may cause abdominal pain, headache, constipation, nausea, and breast pain/enlargement. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Use Nidaglan Vaginal gel as directed by your doctor. It is intended for intra-vaginal use only. Wash your hands thoroughly with soap and water before and after each use. Ensure the vaginal area is clean and dry before applying the medicament.

Inform your doctor if you are allergic to it. Before using Nidaglan Vaginal gel inform your doctor if you have/had liver or kidney problems, heart problems, diabetes, asthma, epilepsy, migraine or depression. Let your doctor know if you are pregnant or breastfeeding. Avoid smoking and alcohol consumption as it can worsen the condition.

Uses of Nidaglan Vaginal gel

Nidaglan Vaginal gel is used in the treatment of female infertility. The detailed uses of Nidaglan Vaginal gel are as follows:

  • Luteal Phase Support: Nidaglan Vaginal gel is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilisation (IVF), increasing the chances of pregnancy.
  • Menstrual Disorders: Nidaglan Vaginal gel helps regulate the menstrual cycle and manage symptoms related to irregular menstruation.
  • Endometrial Preparation: Nidaglan Vaginal gel aids in preparing the endometrium for implantation during fertility treatments, ensuring an optimal environment for a fertilised egg.
  • Prevention of Miscarriage: In some cases, Nidaglan Vaginal gel is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy and provide support during its early stages.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions before using Nidaglan Vaginal gel. Gently insert the applicator into the vagina while lying down or standing with one leg raised. Push the plunger to release the medication.
  • Wash your hands thoroughly with soap and water. Ensure the vaginal area is clean and dry.
  • Remove the applicator carefully and remain lying down for a few minutes to allow the medication to absorb.

Medicinal Benefits

  • Nidaglan Vaginal gel contains progesterone, which helps with ovulation and menstruation.
  • It also causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps maintain pregnancy.
  • It is also used to restore the menstrual cycle in women who have missed their periods.

How Nidaglan Vaginal gel Works

Nidaglan Vaginal gel contains progesterone, a female hormone that regulates ovulation and menstruation in women. Nidaglan Vaginal gel induces secretory changes in the endometrium lining of the uterus, relaxes the uterus, blocks the maturation and release of follicles and maintains pregnancy.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nidaglan Vaginal gel out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nidaglan Vaginal gel
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Talk to your doctor to determine the underlying cause of bleeding between periods and discuss appropriate treatment options.
  • To avoid infection, use sanitary items and change them frequently as part of proper hygiene.
  • Engage in moderate exercise, like walking, cycling, or swimming, to help regulate your menstrual cycle.
  • To lower the chance of hormonal imbalances and intermenstrual bleeding, maintain a healthy weight.
  • Apply a warm compress to the lower abdomen to ease cramps.
  • Seek medical attention if you experience heavy or prolonged bleeding between periods.

What if I have taken an overdose of Nidaglan Vaginal gel

Avoid exceeding the recommended dose as it might cause an overdose. Consult the doctor if you experience any unusual symptoms.

Drug Warnings

  • Do not use Nidaglan Vaginal gel if you are allergic to any of its components
  • Let your doctor know if you have if you have any history of unexplained vaginal bleeding, porphyria, cancer, thrombophlebitis and missed abortion or miscarriage.
  • Keep your doctor informed about your health condition and all the medicines you are taking before taking Nidaglan Vaginal gel to rule out any side effects/interactions.
  • If you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Nidaglan Vaginal gel.
  • Nidaglan Vaginal gel is not recommended for children below 18 years of age.
  • Before taking this medication, your doctor will do a smear test and examine your breasts and pelvic area.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • It is critical to lose weight and maintain a healthy BMI in order to boost fertility.
  • Caffeine and caffeinated drinks should be avoided for improved fertility.
  • Reduce your carbohydrate intake and eat more antioxidant-rich foods.
  • Include beans, lentils, Greek yoghurt, cheese, probiotics, and vitamin D, as they aid in ovulation.
  • Asparagus should be included in your everyday diet. Asparagus is a superfood that has amazing benefits for women attempting to conceive.
  • Quit smoking.
  • Avoid consumption of alcohol.

Habit Forming

No

Therapeutic Class

HORMONES

Nidaglan Vaginal gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol affects Nidaglan Vaginal gel. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Contact the doctor before using Nidaglan Vaginal gel. Your doctor will decide whether Nidaglan Vaginal gel should be used by the pregnant woman or not depending on her condition.

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Breast Feeding

Unsafe

The use of Nidaglan Vaginal gel during breastfeeding is not recommended.

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Driving

Caution

Nidaglan Vaginal gel does not influence the ability to drive and use machines.

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Liver

Unsafe

Do not use Nidaglan Vaginal gel if you have/had liver disease or abnormal liver tests.

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Kidney

Consult your doctor

Please consult your doctor if you have aany kidney disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Nidaglan Vaginal gel is not recommended for use in children or adolescents.

Have a query?

FAQs

Nidaglan Vaginal gel belongs to the class of medicines known as hormones used to treat female infertility and to aid pregnancy. It is also used to restore the menstrual cycle in women who have missed their periods.

Nidaglan Vaginal gel causes secretory changes in the uterine endometrium, relaxes the uterus, prevents follicle maturation, and helps to maintain pregnancy.

Do not use Nidaglan Vaginal gel if you are allergic to any of its components or if you have/had porphyria, breast or genital cancer, abnormal vaginal bleeding due to miscarriage or missed abortion, blood clots or stroke, liver disease or abnormal liver tests.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high estrogen levels, and women can have decreased sex drive, weight gain or gallbladder problems.

Nidaglan Vaginal gel may cause vaginal spotting, vaginal irritation, or application site reactions. Consult your doctor if the condition persists or worsens.

Country of origin

India

Manufacturer/Marketer address

Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India
Other Info - NIDA313

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 8, 2025 | 11:30 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1283.pdf
  2. https://www.medicines.org.uk/emc/product/1283/smpc
  3. https://www.medsafe.govt.nz/Consumers/cmi/c/crinone.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020701s026lbl.pdf
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