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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Niconova I.V. 48 Injection prevents or treats angina pectoris (heart-related chest pain). It contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels, relaxes these muscle cells, and widens blood vessels. Thus, it reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, it helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

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Composition :

NICORANDIL-48MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Niconova I.V. 48 Injection

Niconova I.V. 48 Injection is mainly used to prevent or treat angina pectoris in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.

Niconova I.V. 48 Injection contains Nicorandil, that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels.

Some people may experience side effects such as headache, nausea, vomiting, dizziness, injection site reactions, weakness or flushing (reddening of the skin). Most of these side effects of Niconova I.V. 48 Injection do not require medical attention and resolve over time. However, if the side effects persist, please consult your doctor.

Niconova I.V. 48 Injection will be administered by a healthcare professional; do not self-administer. The dose of the medicine will be decided by the physician based on the severity of the disease.

If you are allergic to Niconova I.V. 48 Injection or any other medicines, please tell your doctor. Inform your doctor if you are pregnant or breastfeeding. Niconova I.V. 48 Injection is not recommended for children as the safety and effectiveness were not been established. It is advised to drive only if you are alert as Niconova I.V. 48 Injection may cause dizziness or weakness. Avoid alcohol consumption with Niconova I.V. 48 Injection as it may cause severely low blood pressure.

Uses of Niconova I.V. 48 Injection

Niconova I.V. 48 Injection is used in the treatment of angina pectoris (heart-related chest pain). The detailed use of Niconova I.V. 48 Injection is as follows:

  • Treatment of Angina Pectoris: Niconova I.V. 48 Injection manages angina effectively by reducing chest pain frequency and severity, enhancing exercise capacity, and improving quality of life through potassium channel-mediated vasodilation.

Directions for Use

  • Niconova I.V. 48 Injection is given only in clinical settings by healthcare professionals, usually through slow intravenous injection.
  • The dose and duration are decided by the doctor, based on the patient's condition and response to treatment.
  • Do not self-administer this injection, as incorrect use can lead to serious side effects.

Medicinal Benefits

  • Niconova I.V. 48 Injection contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain).
  • Niconova I.V. 48 Injection helps reduce the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen.
  • Also, Niconova I.V. 48 Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
  • Niconova I.V. 48 Injection is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers. 

How Niconova I.V. 48 Injection Works

Niconova I.V. 48 Injection contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Niconova I.V. 48 Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Niconova I.V. 48 Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Storage

• Store in a cool and dry place away from sunlight.• Keep Niconova I.V. 48 Injection out of reach and sight of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Niconova I.V. 48 Injection

As Niconova I.V. 48 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

  • Inform your doctor if you are allergic to Niconova I.V. 48 Injection or any other components present in it.
  • Avoid receiving Niconova I.V. 48 Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems.
  • Do not take Niconova I.V. 48 Injection if you are pregnant or breastfeeding, and consult a doctor.
  • Niconova I.V. 48 Injection is not recommended for children as the safety and effectiveness have not been established.
  • Avoid alcohol consumption with Niconova I.V. 48 Injection as it may cause severely low blood pressure.
  • Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Niconova I.V. 48 Injection as it may affect blood pressure.
  • If you notice in blood in stools while administration with Niconova I.V. 48 Injection, inform your doctor immediately, as it may be due to ulcers in the stomach, intestines or back passage. 

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low-salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

VASODILATORS
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Niconova I.V. 48 Injection as it may cause severely low blood pressure.

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Pregnancy

Unsafe

There is limited information on the use of Niconova I.V. 48 Injection in pregnant women. Usually, it is not recommended for pregnant women. Therefore, if you are pregnant or planning pregnancy, please inform your doctor.

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Breast Feeding

Consult your doctor

There is limited information on the use of Niconova I.V. 48 Injection in breastfeeding mothers. Therefore, please inform your doctor if you are a breastfeeding mother.

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Driving

Unsafe

Niconova I.V. 48 Injection may cause dizziness or weakness in some people. Therefore, avoid driving if you feel dizzy or weak after receiving Niconova I.V. 48 Injection.

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Liver

Caution

Take Niconova I.V. 48 Injection with caution, especially if you have a history of liver disease.

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Kidney

Caution

Take Niconova I.V. 48 Injection with caution, especially if you have a history of kidney disease.

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Children

Unsafe

Niconova I.V. 48 Injection is not recommended for children as safety and effectiveness were not established.

Have a query?

FAQs

Niconova I.V. 48 Injection is used to treat Angina pectoris (heart-related chest pain).

Niconova I.V. 48 Injection contains Nicorandil which works by relaxing and widening blood vessels. Thereby, Niconova I.V. 48 Injection reduces the workload of the heart by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Niconova I.V. 48 Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Niconova I.V. 48 Injection may cause headache as a common side effect, especially in the first few days of treatment. However, if the condition persists or worsens, please consult a doctor so that the dose may be reduced initially.

Niconova I.V. 48 Injection is not recommended for patients with severe hypotension (low blood pressure) as it may increase the risk of worsening the condition. Therefore, inform your doctor if you have low blood pressure before taking Niconova I.V. 48 Injection.

You are not recommended to take aspirin (pain reliever) with Niconova I.V. 48 Injection as co-administration of these two medicines may increase the risk of ulcers or other adverse effects. However, please consult a doctor before taking other medicines with Niconova I.V. 48 Injection.

You are recommended to avoid receiving Niconova I.V. 48 Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems such as left ventricular failure with low filling pressure, cardiac decompensation or cardiogenic shock.

You are not recommended to take more than the prescribed dose of Niconova I.V. 48 Injection as it may cause Niconova I.V. 48 Injection overdose resulting in symptoms such as weakness, dizziness (signs of low blood pressure), and fast or irregular heartbeat. However, if you experience any of these symptoms while receiving Niconova I.V. 48 Injection, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

4th Floor, RKL Business Center Kokane Chowk, Pimple Saudagar, Pune-411027
Other Info - NI56870

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