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Neotagmin-P Injection 5 ml is an anticholinergic agents which is used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants. This medicine works by inhibiting an enzyme responsible for breaking down acetylcholine (involved in nerve impulse transmission and muscle action). Common side effects include constipation, dry mouth, nausea, vomiting, visual disturbance, dizziness, diarrhoea, and injection site reactions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Neotagmin-P Injection 5 ml

Neotagmin-P Injection 5 ml is a prescription injection used at the end of a surgical procedure to reverse the effects of certain muscle-relaxing medicines. It helps restore your normal muscle function, allowing you to breathe on your own and move safely as you wake up from anaesthesia. This medication is always administered by a healthcare professional in a controlled hospital setting.

Because Neotagmin-P Injection 5 ml is given as a single injection by your medical team during your recovery, you do not need to worry about keeping a regular dosing schedule. There are no direct dietary rules for this medicine, but resting and drinking fluids once permitted will help support your body's recovery after surgery.

While recovering, some people may experience mild side effects from Neotagmin-P Injection 5 ml, such as a dry mouth, temporary changes in heart rate, or mild nausea. Although they are rare, serious side effects like severe breathing difficulties or allergic reactions can occur, and your medical team will monitor you closely to treat these immediately if they happen.

Do not take this if you have a known blockage in your bowels or urinary tract. Before your surgery, it is vital to tell your doctor if you have asthma, heart disease, an abnormal heart rhythm, epilepsy, or kidney problems so they can plan your care safely.

Neotagmin-P Injection 5 ml can interact with certain other medicines, such as specific heart medications, which may affect how your body responds. Always inform your healthcare team about all the medications you are taking, and consult your doctor if you are pregnant, breastfeeding, or an older adult to ensure this treatment is safe for you.

Uses of Neotagmin-P Injection 5 ml

Neotagmin-P Injection 5 ml is used to reverse the effects of certain muscle-relaxing medicines after surgery. The detailed uses of Neotagmin-P Injection 5 ml are as follows:

  • Reversal of muscle relaxants after surgery: After you undergo a procedure where muscle-relaxing medicines are used, Neotagmin-P Injection 5 ml helps quickly restore your muscle strength so you can breathe naturally and move safely.
  • Prevention of unwanted surgical side effects: While reversing muscle relaxants, Neotagmin-P Injection 5 ml helps keep your heart rate stable and prevents excess saliva or fluid buildup in your airway.

Key Benefits

Neotagmin-P Injection 5 ml supports a safe and smooth recovery after surgery by reversing the effects of certain muscle-relaxing medicines. The key benefits of Neotagmin-P Injection 5 ml include:

  • Speeds up post-surgical recovery: By quickly reversing the effects of anaesthesia-related muscle relaxants, Neotagmin-P Injection 5 ml helps you wake up and regain your physical strength faster while in the recovery room.
  • Supports safe and natural breathing: This medication restores the strength of your breathing muscles, reducing the amount of time you need to rely on a breathing machine or ventilator after surgery.
  • Protects heart and airway health: The combination of active components works in harmony to prevent dangerous drops in your heart rate and keeps your airway dry and clear, ensuring a safer and more comfortable wake-up process.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Neotagmin-P Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Neotagmin-P Injection 5 ml Works

Neotagmin-P Injection 5 ml contains glycopyrrolate and neostigmine methylsulphate. Neostigmine methylsulphate works by increasing the levels of acetylcholine, a natural chemical messenger in the body that stimulates muscle contraction. This action reverses the effects of certain muscle-relaxing medicines used during surgery, helping to restore normal muscle strength. Glycopyrrolate works by blocking the unwanted effects of increased acetylcholine on other parts of the body. It helps prevent side effects such as a very slow heart rate, excessive saliva production, and increased airway secretions, helping to keep your heart rate stable and your airway clear during recovery from anaesthesia.
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Alcohol

Unsafe

Avoid consuming alcohol after taking Neotagmin-P Injection 5 ml as it may cause increased dizziness.

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Pregnancy

Caution

Neotagmin-P Injection 5 ml contains Neostigmine which is a pregnancy category C drug. It may be unsafe for use during pregnancy since animal studies of Neotagmin-P Injection 5 ml showed harmful effects on the fetus. Please inform your doctor before taking the Neotagmin-P Injection 5 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

There is no substantial research yet on using Neotagmin-P Injection 5 ml in breastfeeding/nursing mothers. Your doctor will weigh the benefits and potential risks before prescribing Neotagmin-P Injection 5 ml.

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Driving

Unsafe

Neotagmin-P Injection 5 ml can make you feel dizzy, have weak eyesight, and affect your driving ability. It is advised not to drive or operate machinery if you are not mentally alert and focused.

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Liver

Caution

If you have pre-existing or a history of liver-related diseases, please inform your doctor before taking the Neotagmin-P Injection 5 ml. Your doctor will weigh the benefits and potential risks before prescribing Neotagmin-P Injection 5 ml.

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Kidney

Caution

If you have pre-existing or a history of kidney-related diseases, please inform the doctor before taking the Neotagmin-P Injection 5 ml. Your doctor will weigh the benefits and potential risks before prescribing Neotagmin-P Injection 5 ml.

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Children

Caution

Neotagmin-P Injection 5 ml can be given to children if medically needed.

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Heart

Caution

Neotagmin-P Injection 5 ml should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Neotagmin-P Injection 5 ml.

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Geriatrics

Caution

Neotagmin-P Injection 5 ml should be administered with caution in elderly patients due to an increased risk of side effects.

What if I have taken an overdose of Neotagmin-P Injection 5 ml

This medication is carefully measured and administered by trained medical professionals in a hospital environment, making an overdose highly unlikely. However, if an overdose does occur, the hospital medical team is trained to recognise the signs such as severe muscle weakness, breathing problems, or an extremely slow heart rate and will treat it immediately.

Diet & Lifestyle Advise

  • Rest and recover: Give your body plenty of time to rest after your surgery to allow your muscles and overall system to heal completely.
  • Stay hydrated: Sip water slowly once your healthcare team confirms it is safe to drink, which helps ease dry mouth and flush out surgical medicines.
  • Eat soft foods first: Start with light, easily digestible foods like broth, gelatin, or crackers once allowed, to prevent nausea after your procedure.
  • Avoid heavy lifting: Refrain from strenuous physical activity or lifting heavy objects until your doctor confirms your muscle strength has fully returned.
  • Follow mobilisation guidelines: Gently move your legs or walk short distances as advised by your nurse to support blood circulation and muscle recovery.
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How Soon It Starts Working

The time required for Neotagmin-P Injection 5 ml to start to work: Neotagmin-P Injection 5 ml shows its effect within 15 to 30 minutes of administration. The time for which the effects of Neotagmin-P Injection 5 ml last:Neotagmin-P Injection 5 ml effect lasts for 2 to 4 hours.

What if you forget to take Neotagmin-P Injection 5 ml

Because Neotagmin-P Injection 5 ml is given as a single injection by a healthcare professional during surgery, missing a dose is not possible.

Storage

•Store Neotagmin-P Injection 5 ml at controlled room temperature, between 20°C and 25°C (68°F to 77°F).•Do not freeze the injection solution. Keep the medication in its original packaging to protect it from direct light.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Visual inspection: Before administration, the healthcare professional must inspect the solution to ensure it is clear, colourless, and free of visible particles.
  • Inform your anesthesiologist: Always share your complete medical history, including any history of asthma, heart conditions, or kidney disease, before your surgery begins.
  • Monitor your vitals: Your medical team will continuously monitor your heart rhythm, blood pressure, and oxygen levels while Neotagmin-P Injection 5 ml is being administered.
  • Avoid driving: Do not drive, operate heavy machinery, or perform tasks requiring deep concentration for at least 24 hours after receiving this medicine, as anaesthesia can temporarily slow your reflexes.
  • Report breathing changes: Let your nurse or doctor know immediately if you feel like your breathing is shallow or if you feel exceptionally weak after waking up.

Drug-Drug Interactions

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  • Other muscle relaxants: May interfere with or prolong the action of certain surgical muscle relaxants.
  • Heart medications (like beta-blockers): Combining these can cause your heart rate to drop dangerously low.
  • Anticholinergic drugs: May increase the risk of side effects like dry mouth, blurred vision, or constipation.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: There are no known direct interactions between Neotagmin-P Injection 5 ml and specific foods, as it is administered directly into the bloodstream during surgery.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS]

FAQs

Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants.
Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants. Neotagmin-P Injection 5 ml is composed of Glycopyrrolate and Neostigmine. Neostigmine boosts acetylcholine levels by blocking an enzyme that degrades acetylcholine, which is involved in nerve impulse transmission and muscle activity. On the other hand, Glycopyrrolate is an anticholinergic that reduces the unfavourable effects of Neostigmine, such as slow heart rate and increased saliva production.
Do not use Neotagmin-P Injection 5 ml in people with difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. As a precautionary measure, please let your doctor know if you have any other medical problems before starting Neotagmin-P Injection 5 ml.
Neotagmin-P Injection 5 ml is prescription-only medication available in the form of injection. It is administered by a qualified healthcare professional. Do not self-administer.
It is not required to utilise Neotagmin-P Injection 5 ml in every patient following surgery. It can only be used to reverse the effects of medications used during surgery based on the patient's medical state following surgery.
Keep the Neotagmin-P Injection 5 ml in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.
This medicine is injected directly into a vein (intravenously) by a trained healthcare professional, typically an anesthesiologist, in a hospital or operating room setting. Talk to your doctor for more details.
While Neotagmin-P Injection 5 ml itself does not directly cause drowsiness, the anaesthesia and other surgical medicines you received will likely make you feel sleepy for several hours. Talk to your doctor about what to expect.
Neotagmin-P Injection 5 ml is only used during pregnancy if the potential benefits outweigh the risks. Your surgical team will evaluate your condition carefully. Talk to your doctor if you are pregnant or planning a pregnancy.
Alert your nurse or doctor immediately if you feel weak or have trouble breathing in the recovery room. They will monitor you closely and provide the necessary care. Talk to your doctor if you have ongoing concerns.
No, this medicine is used as a single dose during surgery and leaves your body relatively quickly, so long-term side effects are extremely rare. Talk to your doctor if you experience persistent symptoms after your surgery.
You must wait until your healthcare team confirms that your swallowing reflexes have fully returned and it is safe to eat or drink. Talk to your doctor or nurse for specific post-surgery instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - NEO0392
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