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NEOPRATE INJECTION 5ML is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It helps reduce mood swings and improve impulsive behaviour.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About NEOPRATE INJECTION 5ML

NEOPRATE INJECTION 5ML is a specialised injection used to treat various types of seizures and epilepsy in patients who cannot take medicines by mouth. It works by calming overactive nerve signals in the brain to help control and prevent sudden seizure episodes. This medicine is typically injected in hospital or clinical settings under professional supervision to ensure safety and effectiveness.

Because this medicine is given directly into a vein, a healthcare professional will manage your treatment schedule to ensure you receive consistent and timely doses. While receiving this therapy, maintaining a regular sleep schedule and avoiding extreme stress can support your recovery. It is also helpful to stay well-hydrated and follow any specific dietary plans recommended by your healthcare team.

Some people may experience mild side effects like dizziness, sleepiness, or mild nausea after receiving an injection. However, you must tell your healthcare provider immediately if you notice serious symptoms such as severe stomach pain, unusual bruising, or yellowing of your eyes and skin.

Before receiving NEOPRATE INJECTION 5ML, tell your doctor if you have a history of liver problems, kidney disease, or mitochondrial disorders. Do not take this medicine if you have active liver disease or a family history of severe liver damage. It is also crucial to tell your doctor if you are pregnant or planning to become pregnant, as this medicine can cause harm to an unborn baby.

This medicine can interact with other seizure medications, blood thinners, and alcohol, which may increase your risk of severe sleepiness or bleeding. Women who are pregnant or breastfeeding, as well as elderly individuals, should discuss the risks and benefits thoroughly with their doctor before receiving this treatment.

Uses of NEOPRATE INJECTION 5ML

Your doctor may prescribe NEOPRATE INJECTION 5ML to help manage the following conditions:

  • Status epilepticus: It helps quickly control rapid, continuous seizure activity when immediate emergency treatment is critical.
  • Epilepsy and various seizure types: It is used to control generalised, partial, or other complex seizures when oral medication is temporarily not possible.
  • Prevention of seizures after surgery or trauma: It helps prevent brain seizure activity following brain surgery or head injuries.
     

Key Benefits

When used as directed as part of your treatment plan, NEOPRATE INJECTION 5ML may provide the following benefits:

  • Helps control seizures: Helps reduce or prevent seizures in people with epilepsy and other seizure disorders.
  • Supports continuous seizure management: Helps maintain seizure control when oral treatment is temporarily not possible.
  • May reduce the risk of seizure-related complications: Effective seizure control may help lower the risk of injury and other complications associated with seizures.
  • Supports brain stability during acute illness: Helps maintain stable brain activity in people requiring intravenous treatment for seizure control.
  • Supports continuity of care: Allows essential anti-seizure treatment to continue until you can safely switch back to oral medicine, if appropriate.
Side effects of Neoprate Injection 5ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • NEOPRATE INJECTION 5ML will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How NEOPRATE INJECTION 5ML Works

NEOPRATE INJECTION 5ML contains sodium valproate. Sodium valproate belongs to a group of medicines called antiepileptics (medicines used to prevent and control seizures). It works by increasing the activity of gamma-aminobutyric acid (GABA) (a natural chemical in the brain that helps calm nerve cells and reduce excessive electrical activity). It also helps regulate the movement of sodium channels (pathways that allow electrical signals to travel between nerve cells), making overactive nerve cells less likely to fire repeatedly. Together, these actions help stabilise electrical activity in the brain, reducing the likelihood of seizures.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking NEOPRATE INJECTION 5ML as it may cause increased dizziness and sleepiness.

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Pregnancy

Consult your doctor

NEOPRATE INJECTION 5ML may cause serious congenital defects and decreased IQ. Therefore, NEOPRATE INJECTION 5ML should be given to pregnant women with epilepsy only if other medicines have failed to control their symptoms or are unacceptable.

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Breast Feeding

Consult your doctor

NEOPRATE INJECTION 5ML may pass into breastmilk. Consult your doctor before taking NEOPRATE INJECTION 5ML if you are breastfeeding.

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Driving

Unsafe

NEOPRATE INJECTION 5ML causes dizziness, sleepiness and tiredness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Unsafe

NEOPRATE INJECTION 5ML may cause hepatotoxicity (liver damage). Therefore, it is not recommended for people with hepatic dysfunction. Please inform your doctor if you have a liver impairment or liver problem.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

NEOPRATE INJECTION 5ML can be given to children above 2 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight. NEOPRATE INJECTION 5ML should be used with extreme caution in children below 2 years as it might cause hepatotoxicity (liver damage).

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Heart

Caution

If you have any history of heart disease before taking NEOPRATE INJECTION 5ML, please inform your doctor. Your doctor may adjust the dose based on your condition.

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Geriatrics

Caution

NEOPRATE INJECTION 5ML should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of NEOPRATE INJECTION 5ML

Since this medicine is given by medical professionals, an overdose is highly unlikely. However, if you suspect you have received too much or experience severe sleepiness, shallow breathing, or confusion, tell your healthcare provider or seek emergency medical help immediately.

Diet & Lifestyle Advise

  • Maintain a consistent sleep schedule: Lack of sleep is a well-known trigger for seizures, so aim for 7 to 8 hours of restful sleep every night.
  • Stay well-hydrated: Drink plenty of water throughout the day, as dehydration can stress your nervous system.
  • Avoid alcohol completely: Alcohol can interfere with how this medicine works in your brain and significantly increase your risk of severe drowsiness and seizures.
  • Eat regular meals: Keeping your blood sugar stable by not skipping meals can help reduce the likelihood of seizure triggers.
  • Manage stress: Practice relaxation techniques such as deep breathing or gentle yoga, as high stress levels can lower your seizure threshold.
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Have a query?

How Soon It Starts Working

  • The time required for NEOPRATE INJECTION 5ML to start to work: NEOPRATE INJECTION 5ML ideally shows its action within 15 to 30 minutes after administration.
  • The time for which the effects of NEOPRATE INJECTION 5ML last: The duration of action for NEOPRATE INJECTION 5ML is clinically unknown.

What if you forget to take NEOPRATE INJECTION 5ML

Because this medicine is typically injected by a healthcare provider in a hospital or clinic, a missed dose is highly unlikely. However, if you miss an appointment for your injection, contact your healthcare provider immediately to reschedule. Do not receive a double dose to make up for a missed one.

Storage

•Store the medication at room temperature, ideally between 15°C and 30°C (59°F to 86°F). .•Keep the vials or ampoules in their original packaging to protect them from direct light.

Drug Warnings

  • Inspect the vial before use: Always check the injection liquid before it is given. Do not use it if you see particles, cloudiness, or any discolouration.
  • Monitor your liver function: Your doctor will need to perform regular blood tests to check your liver health, especially during the first six months of treatment.
  • Use effective birth control: This medicine can cause severe birth defects. If you are a female of childbearing age, discuss highly effective birth control options with your doctor.
  • Do not stop treatment suddenly: Stopping this medicine abruptly can cause your seizures to return or become more severe. Always consult your doctor before making any changes.
  • Avoid driving or operating machinery: This medicine can make you feel dizzy or sleepy. Do not perform tasks that require focus until you know how it affects you.
  • Pregnancy and contraception: If you can become pregnant, use effective contraception while receiving this medicine. Your doctor should review your treatment and contraception at least once a year. Consult your doctor right away if you are pregnant, think you may be pregnant, or plan to become pregnant. Do not stop this medicine without medical advice.

Drug-Drug Interactions

verifiedApollotooltip
  • Other anti-seizure medicines (such as carbamazepine, phenytoin, phenobarbital, lamotrigine, or topiramate): May affect sodium valproate levels or increase the risk of side effects. Your doctor may need to adjust your treatment.
  • Carbapenem antibiotics (such as meropenem, imipenem, or ertapenem): May greatly reduce sodium valproate levels, making it less effective at preventing seizures. This combination is generally avoided whenever possible.
  • Blood thinners (such as warfarin): May increase the risk of bleeding.
  • Aspirin: May increase sodium valproate levels and the risk of side effects, particularly in children.
  • Medicines that cause drowsiness (such as sleeping tablets, opioid pain medicines, or some anti-anxiety medicines): May increase drowsiness and reduce alertness.
Sodium ValproateSodium phenylbutyrate
Critical
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Neoprate Injection 5ml:
Combining Sodium phenylbutyrate and Neoprate Injection 5ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Neoprate Injection 5ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Vorinostat with Neoprate Injection 5ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Neoprate Injection 5ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Meropenam and Neoprate Injection 5ml together can reduce the effect of Neoprate Injection 5ml.

How to manage the interaction:
Co-administration of Meropenam and Neoprate Injection 5ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neoprate Injection 5ml:
Using buprenorphine together with Neoprate Injection 5ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Neoprate Injection 5ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Leflunomide and Neoprate Injection 5ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Neoprate Injection 5ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Lithium with Neoprate Injection 5ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Neoprate Injection 5ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Ketamine and Neoprate Injection 5ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Neoprate Injection 5ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Teriflunomide and Neoprate Injection 5ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Neoprate Injection 5ml:
The combined use of Ertapenem and Neoprate Injection 5ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with NEOPRATE INJECTION 5ML when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

NEOPRATE INJECTION 5ML belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder.
NEOPRATE INJECTION 5ML decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.
NEOPRATE INJECTION 5ML may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.
NEOPRATE INJECTION 5ML may cause hepatotoxicity (liver damage). Consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Serum liver tests before starting NEOPRATE INJECTION 5ML and at regular intervals for at least six months are advised.
NEOPRATE INJECTION 5ML should not be administered to women of childbearing age unless it is essential to manage their condition. Women of child-bearing age must use effective contraception whilst on treatment with NEOPRATE INJECTION 5ML.
NEOPRATE INJECTION 5ML may cause side effects, such as sleepiness, weakness, dizziness, nausea, and headache. Talk to your doctor if you experience these side effects persistently.
No, NEOPRATE INJECTION 5ML injection is a parenteral medication that must be prepared and given by a trained healthcare professional in a clinic or hospital setting to monitor your safety. Talk to your doctor if you have questions about where you will receive your treatment.
This medicine can cause severe birth defects and developmental problems in unborn babies. It should only be used during pregnancy if there is no other safe option. Talk to your doctor immediately if you are pregnant or planning to become pregnant.
Dizziness is a common side effect of this medicine. Rest quietly, avoid standing up too quickly, and do not drive or use machinery until the feeling passes. Talk to your doctor if your dizziness is severe or does not go away.
You should avoid alcohol while receiving this medicine. Alcohol can increase side effects like severe drowsiness and can also increase your risk of having a seizure. Talk to your doctor for advice on lifestyle habits.
Blood tests are essential to monitor your liver function, blood clotting cells, and the level of the medicine in your body to ensure the treatment is both safe and effective. Talk to your doctor about your schedule for blood tests.

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Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - NEO0349
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