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Naprosyn ES+ 500 mg Capsule 10's is a painkiller medicine used to relieve pain. This combination medicine has anti-inflammatory properties which work by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce prostaglandins that cause pain and swelling. You may experience common side effects like indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Naprosyn ES+ 500 mg Capsule 10's

Naprosyn ES+ 500 mg Capsule 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers used to reduce and relieve pain. Pain is a highly unpleasant physical sensation caused by illness or injury.

Naprosyn ES+ 500 mg Capsule 10's combines Naproxen (painkiller) and esomeprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, combined with esomeprazole (proton pump inhibitors), it reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Take Naprosyn ES+ 500 mg Capsule 10's as prescribed by your doctor. You are advised to take Naprosyn ES+ 500 mg Capsule 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea. Most of these side effects of Naprosyn ES+ 500 mg Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking this medicine, inform your doctor if you have any known allergy to Naproxen, esomeprazole, other NSAIDs, or other medications. If pregnant or breastfeeding, please inform your doctor before taking the Naprosyn ES+ 500 mg Capsule 10's. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use Naprosyn ES+ 500 mg Capsule 10's only when prescribed by a doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Naprosyn ES+ 500 mg Capsule 10's to rule out any side effects.

Uses of Naprosyn ES+ 500 mg Capsule 10's

Naprosyn ES+ 500 mg Capsule 10's is used in the treatment of Pain. The detailed uses of Naprosyn ES+ 500 mg Capsule 10's are as follows:

  • Osteoarthritis, Rheumatoid Arthritis & Ankylosing Spondylitis: Naprosyn ES+ 500 mg Capsule 10's relieves joint pain, stiffness, and swelling.
  • Tendonitis, Bursitis, Gout: Naprosyn ES+ 500 mg Capsule 10's is used in short-term relief of inflammation and pain.
  • Peptic Ulcer Prevention: Naprosyn ES+ 500 mg Capsule 10's reduces stomach acid to prevent ulcers.

Key Benefits

Naprosyn ES+ 500 mg Capsule 10's contains Naproxen and esomeprazole (antacid). Naproxen is an anti-inflammatory (reduces inflammation) and an analgesic (relieves pain) agent that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. It also treats fibrositis (muscle pain and stiffness), tenosynovitis (swelling of tendons), low back pain, strains, and sprains. NSAIDs such as Naproxen have been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. To reduce gastric discomfort and stomach ulceration risk, it is combined with esomeprazole (a proton pump inhibitor that inhibits gastric acid secretion) to reduce stomach acid production during long-term treatment for people with pre-existing stomach ulcers or for people having a history of developing stomach ulcers while using NSAIDs. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Directions for Use

  • Naprosyn ES+ 500 mg Capsule 10's should be taken on an empty stomach at least 30 minutes before a meal.
  • It is usually taken 2 times a day or as prescribed by your doctor.
  • Swallow Naprosyn ES+ 500 mg Capsule 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Naprosyn ES+ 500 mg Capsule 10's Works

Naprosyn ES+ 500 mg Capsule 10's combines Naproxen (painkiller) and esomeprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce certain chemical substances (prostaglandins) that cause pain and swelling. This helps reduce mild to moderate pain and inflammation at the injured or damaged site, decreasing joint stiffness. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, combined with esomeprazole (proton pump inhibitors), it reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Naprosyn ES+ 500 mg Capsule 10's as it may increase the risk of stomach bleeding and ulcer.

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Pregnancy

Caution

There is limited data on how Naprosyn ES+ 500 mg Capsule 10's affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Naprosyn ES+ 500 mg Capsule 10's.

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Breast Feeding

Caution

Naprosyn ES+ 500 mg Capsule 10's passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Naprosyn ES+ 500 mg Capsule 10's. Your doctor will weigh the benefits and any potential risks before prescribing Naprosyn ES+ 500 mg Capsule 10's to you.

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Driving

Caution

Naprosyn ES+ 500 mg Capsule 10's may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Naprosyn ES+ 500 mg Capsule 10's.

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Liver

Caution

Naprosyn ES+ 500 mg Capsule 10's is to be used with caution in people having liver diseases. Dose adjustments may be necessary. So, you should use it only with your doctor's prescription.

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Kidney

Caution

Naprosyn ES+ 500 mg Capsule 10's is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.

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Children

Caution

Naprosyn ES+ 500 mg Capsule 10's should be used in children below 12 years of age only when prescribed by a child specialist.

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Heart

Caution

Naprosyn ES+ 500 mg Capsule 10's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Naprosyn ES+ 500 mg Capsule 10's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Naprosyn ES+ 500 mg Capsule 10's.

What if I have taken an overdose of Naprosyn ES+ 500 mg Capsule 10's

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include drowsiness, severe weakness, vomiting, or stomach pain. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Foods containing flavonoids, such as soy, berries, broccoli, grapes and green tea, help reduce inflammation.
  • Include high-fibre-containing foods, berries, cherries, leafy green veggies and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut and kimchi contain probiotics that help prevent excess stomach acid production.
  • Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Avoid smoking and alcohol consumption.

Have a query?

How Soon It Starts Working

The time required for Naprosyn ES+ 500 mg Capsule 10's to start to work: Naprosyn ES+ 500 mg Capsule 10's ideally shows its action within 1 hour after administration. The time for which the effects of Naprosyn ES+ 500 mg Capsule 10's last: The effect of Naprosyn ES+ 500 mg Capsule 10's lasts for 24 hours.

What if you forget to take Naprosyn ES+ 500 mg Capsule 10's

If you miss a dose, take it as soon as you remember. However, if it is time for the next dose, skip the missed dose and take the scheduled dose instead. Avoid taking a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Naprosyn ES+ 500 mg Capsule 10's if you are allergic to Naprosyn ES+ 500 mg Capsule 10's. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin), such as naproxen, may increase the risk of heart attack, stroke, and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, are older, are alcoholics, or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems, so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Naprosyn ES+ 500 mg Capsule 10's is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Naprosyn ES+ 500 mg Capsule 10's. Naprosyn ES+ 500 mg Capsule 10's should not be given to children unless prescribed by a doctor. Do not take any other NSAIDs for pain relief along with Naprosyn ES+ 500 mg Capsule 10's unless prescribed. Prolonged proton pump inhibitors like esomeprazole may cause brittle bones, so your doctor may recommend taking Vitamin D and calcium while using Naprosyn ES+ 500 mg Capsule 10's. Do not consume alcohol with Naprosyn ES+ 500 mg Capsule 10's as it may increase the risk of stomach bleeding or ulcer.

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Drug-Drug Interactions: Naprosyn ES+ 500 mg Capsule 10's may have interaction with anti-inflammatory medicines (e.g. aspirin, ibuprofen), blood thinners (e.g. warfarin, rivaroxaban), steroids (e.g. prednisolone), diuretic medicines (e.g. furosemide), medicines used to treat heart problems and high blood pressure-lowering medicines (e.g. propranolol, enalapril, losartan, candesartan), antidepressants (e.g. citalopram), and medicine used to treat rheumatoid arthritis (e.g. methotrexate)

Drug-Food Interactions: Naprosyn ES+ 500 mg Capsule 10's may interact with alcohol. Therefore, avoid alcohol intake while taking Naprosyn ES+ 500 mg Capsule 10's as it may increase the risk of stomach bleeding and drowsiness, and dizziness.

Drug-Disease Interactions: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever, and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting, and weight loss) should consult a doctor before taking Naprosyn ES+ 500 mg Capsule 10's.

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Habit Forming

No

Therapeutic Class

[NON-STEROIDAL DRUG]

FAQs

Naprosyn ES+ 500 mg Capsule 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers used to reduce and relieve pain.

Naprosyn ES+ 500 mg Capsule 10's contains Naproxen (NSAID or pain reliever) and esomeprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Esomeprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps reduce the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

You are not recommended to take Naprosyn ES+ 500 mg Capsule 10's with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache. If you are supposed to use these medicines together, you are advised to contact your doctor to adjust the dose appropriately to use safely.

Yes, Naprosyn ES+ 500 mg Capsule 10's can alter specific medical tests like neuroendocrine tumors (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test, contact your doctor.

Naproxen in Naprosyn ES+ 500 mg Capsule 10's may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Naprosyn ES+ 500 mg Capsule 10's. However, it is recommended to take Naprosyn ES+ 500 mg Capsule 10's in the dose and for the duration as prescribed by your doctor. It should be not used by the patient who had recent heart bypass surgery (coronary artery bypass graft - CABG).

Naprosyn ES+ 500 mg Capsule 10's does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness. Arthritis is a chronic condition of joints with pain and inflammation.

Naprosyn ES+ 500 mg Capsule 10's is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of an egg from the ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping Naprosyn ES+ 500 mg Capsule 10's. However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking Naprosyn ES+ 500 mg Capsule 10's.

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Author Details

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Country of origin

India

Manufacturer/Marketer address

463, 4 Th Floor, Rpg House, Dr. Annie Besant Road, Worli, Mumbai 400 030. Maharashtra, India
Other Info - NAP0279
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