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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nadogon 3.75mg Injection is used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. It contains Leuprolide which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LEUPROLIDE-3.75MG

Manufacturer/Marketer :

Life Medicare & Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nadogon 3.75mg Injection

Nadogon 3.75mg Injection belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Nadogon 3.75mg Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Take Nadogon 3.75mg Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Nadogon 3.75mg Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

To treat your condition effectually continue taking Nadogon 3.75mg Injection for as long as your doctor has prescribed. Do not stop Nadogon 3.75mg Injection midway.  Avoid taking Nadogon 3.75mg Injection if you are pregnant or breastfeeding because this Nadogon 3.75mg Injection can cause harmful effects on the unborn baby. Both women and men using this Nadogon 3.75mg Injection should use birth control to avoid pregnancy. Nadogon 3.75mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Nadogon 3.75mg Injection is not recommended for children below two years of age. Nadogon 3.75mg Injection may make you feel dizzy, hence drive when you are alert only.

Uses of Nadogon 3.75mg Injection

Nadogon 3.75mg Injection is used in the treatment of Prostate cancer, Endometriosis and Precocious puberty. The detailed uses of Nadogon 3.75mg Injection are as follows:

  • Treat advanced prostate cancer: Nadogon 3.75mg Injection is primarily used to manage symptoms of advanced prostate cancer by lowering testosterone levels, which slows the growth of cancer cells.
  • Manage endometriosis and uterine fibroids: Nadogon 3.75mg Injection helps reduce estrogen production, alleviating pain and other symptoms associated with endometriosis and fibroids, and may be used preoperatively to shrink fibroid size.
  • Treat central precocious puberty (CPP): Nadogon 3.75mg Injection is prescribed for children with CPP to delay early onset of puberty and normalize growth and sexual development.
  • Support fertility treatments and hormone regulation: Nadogon 3.75mg Injection is used in assisted reproductive technologies to control hormone levels and prevent premature ovulation during fertility procedures.
  • Treat anemia caused by uterine fibroids: In combination with other medications, Nadogon 3.75mg Injection helps improve hemoglobin levels by reducing menstrual bleeding linked to fibroids.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Nadogon 3.75mg Injection will be administered by a nurse or doctor.
  • Do not self-administer.

Medicinal Benefits

Nadogon 3.75mg Injection contains Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Nadogon 3.75mg Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Nadogon 3.75mg Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Nadogon 3.75mg Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis and breast cancer.

How Nadogon 3.75mg Injection Works

Nadogon 3.75mg Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nadogon 3.75mg Injection out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Nadogon 3.75mg Injection

Since this medication is given by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Nadogon 3.75mg Injection or any other medicines, please tell your doctor. Nadogon 3.75mg Injection can affect the unborn baby when used in pregnancy. Hence, Nadogon 3.75mg Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Nadogon 3.75mg Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Nadogon 3.75mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Use the Nadogon 3.75mg Injection with caution in elderly patients and children. Nadogon 3.75mg Injection is not recommended for children younger than two years of age. Your symptoms may become temporarily worse when you first start taking Nadogon 3.75mg Injection. Inform your doctor if this continues for longer than 2 months. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting Nadogon 3.75mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Nadogon 3.75mg Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Nadogon 3.75mg Injection. Nadogon 3.75mg Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nadogon 3.75mg Injection:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Nadogon 3.75mg Injection with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nadogon 3.75mg Injection:
Coadministration of Nadogon 3.75mg Injection and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nadogon 3.75mg Injection and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with Nadogon 3.75mg Injection:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with Nadogon 3.75mg Injection:
Taking Nadogon 3.75mg Injection with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nadogon 3.75mg Injection:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with Nadogon 3.75mg Injection:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinIbutilide
Critical
How does the drug interact with Nadogon 3.75mg Injection:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nadogon 3.75mg Injection:
Taking Nadogon 3.75mg Injection with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with Nadogon 3.75mg Injection:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nadogon 3.75mg Injection with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinProcainamide
Severe
How does the drug interact with Nadogon 3.75mg Injection:
Taking leuprolide with procainamide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Nadogon 3.75mg Injection and procainamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Nadogon 3.75mg Injection to avoid unpleasant side-effects. Alcohol intake, along with Nadogon 3.75mg Injection, may cause increased drowsiness.

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Pregnancy

Unsafe

Nadogon 3.75mg Injection is a pregnancy category X drug. Nadogon 3.75mg Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective method of contraception while taking fluorouracil and for at least 6 months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Nadogon 3.75mg Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Nadogon 3.75mg Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Nadogon 3.75mg Injection.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Nadogon 3.75mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Nadogon 3.75mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Caution

Nadogon 3.75mg Injection is not recommended in children younger than two years of age.

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Heart

Caution

Nadogon 3.75mg Injection should be administered with caution, especially if you have a history of heart problems. Please inform your doctor about any existing heart problems before receiving Nadogon 3.75mg Injection.

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Geriatrics

Consult your doctor

Nadogon 3.75mg Injection is generally safe for elderly patients, but should be administered under medical supervision. Seek advice from your doctor if you have any concerns.

FAQs

Nadogon 3.75mg Injection is used to treat prostate cancer in men, breast cancer & endometriosis in women and precocious puberty (early puberty) in children.

Nadogon 3.75mg Injection contains Leuprolide, a synthetic hormone that helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.

Yes, Nadogon 3.75mg Injection commonly affects the hair by making them thin which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen lowering effect of Nadogon 3.75mg Injection. These effects are not long-lasting and may return after some time. If it matters to you then inform your doctor for further advice.

Nadogon 3.75mg Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Nadogon 3.75mg Injection.

Nadogon 3.75mg Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Nadogon 3.75mg Injection and inform your doctor if you have diabetes before taking Nadogon 3.75mg Injection.

Country of origin

India
Other Info - NA42411

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