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  3. Nab-Pacliarc 100 mg Injection 1's

Nab-Pacliarc 100 mg Injection 1's, Pack of 1 INJECTION
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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Nab-Pacliarc 100 mg Injection is an anti-cancer medication used to treat various types of cancer, including breast cancer, pancreatic cancer, and non-small cell lung cancer. It contains Paclitaxel and Human Albumin, which work by inhibiting cell division and preventing the growth of certain cancer cells. Sometimes, Nab-Pacliarc 100 mg Injection may cause common side effects, such as numbness or tingling in hands and feet, tiredness, nausea and vomiting, diarrhea, joint and muscle pain, swelling in hands or feet, and fever.

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Composition :

HUMAN ALBUMIN-900MG + PACLITAXEL-100MG

Manufacturer/Marketer :

Delarc Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nab-Pacliarc 100 mg Injection

Nab-Pacliarc 100 mg Injection belongs to the group of anti-cancer medicines used to treat various types of cancers, including breast cancer, pancreatic cancer, and non-small cell lung cancer. Breast cancer, pancreatic cancer, and non-small cell lung cancer are types of cancer that develop in the breast tissue, pancreas, and lungs, respectively, causing abnormal cell growth and tumor formation.

Nab-Pacliarc 100 mg Injection contains Paclitaxel and Human Albumin, which work together to combat cancer. Paclitaxel stops cell division and prevents the growth of certain cancer cells by stabilizing microtubules, while human albumin acts as a carrier protein, delivering paclitaxel to cancer cells and enhancing its effectiveness.

In some cases, Nab-Pacliarc 100 mg Injection may cause common side effects, such as numbness or tingling in hands and feet, tiredness, nausea and vomiting, diarrhea, hair loss, joint and muscle pain, swelling in hands or feet, and fever. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Please inform your doctor before taking Nab-Pacliarc 100 mg Injection if you are allergic to it or any of its components. It is essential to inform your doctor about any existing heart disease, liver or kidney problems, or medications you're taking to treat infections to ensure safe and effective treatment. Consult your doctor if you are pregnant, breastfeeding, think you may be pregnant, or are planning pregnancy. Nab-Pacliarc 100 mg Injection is not recommended for children under 18 years. Inform your doctor about your health condition and medications to rule out any side effects.

Uses of Nab-Pacliarc 100 mg Injection

Nab-Pacliarc 100 mg Injection is used in the treatment of cancer, including breast cancer, pancreatic cancer, and non-small cell lung cancer. The detailed uses of Nab-Pacliarc 100 mg Injection are as follows:

  • Treatment of Breast Cancer: Nab-Pacliarc 100 mg Injection treats breast cancer by targeting and killing cancer cells and inhibiting tumor growth.
  • Treatment of Pancreatic Cancer: Nab-Pacliarc 100 mg Injection effectively treats pancreatic cancer by targeting cancer cells, often used in combination with gemcitabine (Gemzar) to enhance therapeutic outcomes.
  • Treatment of Non-Small Cell Lung Cancer (NSCLC): Nab-Pacliarc 100 mg Injection treats non-small cell lung cancer by binding to microtubules, disrupting cell division, and inducing apoptosis (cell death.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Nab-Pacliarc 100 mg Injection should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.
  • Do not self-administer.

Medicinal Benefits

Nab-Pacliarc 100 mg Injection provides several medicinal benefits when used together. Paclitaxel exhibits anti-cancer properties, inhibiting cell division, stabilizing microtubules, and inducing apoptosis in cancer cells. Human albumin enhances paclitaxel's delivery to cancer cells, improving its solubility and bioavailability. Additionally, human albumin acts as a plasma volume expander and binding agent, transporting essential substances. Together, they enhance cancer treatment efficacy, improve outcomes, reduce side effects, and increase patient survival rates.

How Nab-Pacliarc 100 mg Injection Works

Nab-Pacliarc 100 mg Injection contains Paclitaxel and Human Albumin, which work together to combat cancer. Paclitaxel stops cell division and prevents the growth of certain cancer cells by stabilizing microtubules, while human albumin acts as a carrier protein, delivering paclitaxel to cancer cells and enhancing its effectiveness.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nab-Pacliarc 100 mg Injection out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nab-Pacliarc 100 mg Injection

As Nab-Pacliarc 100 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or are experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take Nab-Pacliarc 100 mg Injection if you are allergic to Nab-Pacliarc 100 mg Injection or any of its components. Before receiving Nab-Pacliarc 100 mg Injection, inform your doctor if you have low blood cell counts, uncontrolled infections, Kaposi's sarcoma, or severe liver issues. Inform your doctor if you have heart disease, abnormal blood cell counts, irregular heartbeat, tingling, numbness, or a burning sensation in fingers or toes; if you are on radiation therapy; or if you have Kaposi’s sarcoma and have a sore or inflamed mouth. Nab-Pacliarc 100 mg Injection may cause fatigue. Be cautious when driving, operating machinery, or performing activities requiring alertness. Nab-Pacliarc 100 mg Injection is not recommended for children below 18 years. Also, inform your doctor if you are pregnant, breastfeeding, think you are pregnant, or are planning pregnancy.

Drug-Drug Interactions

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PaclitaxelTofacitinib
Severe
PaclitaxelClozapine
Severe

Drug-Drug Interactions

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PaclitaxelTofacitinib
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Taking Tofacitinib with Nab-Pacliarc 100 mg Injection may increase the risk of infection.

How to manage the interaction:
Although taking Nab-Pacliarc 100 mg Injection and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
PaclitaxelClozapine
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Combining Nab-Pacliarc 100 mg Injection with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking Nab-Pacliarc 100 mg Injection with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
PaclitaxelRitonavir
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Taking Ritonavir and Nab-Pacliarc 100 mg Injection may significantly increase the blood levels of Nab-Pacliarc 100 mg Injection.

How to manage the interaction:
Taking Ritonavir with Nab-Pacliarc 100 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case of any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelInfliximab
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Combining Infliximab with Nab-Pacliarc 100 mg Injection can enhance the breakdown of Nab-Pacliarc 100 mg Injection in the body. This can reduce the treatment outcomes and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Nab-Pacliarc 100 mg Injection with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PaclitaxelThalidomide
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Taking thalidomide together with Nab-Pacliarc 100 mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Nab-Pacliarc 100 mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
PaclitaxelBaricitinib
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Coadministration of baricitinib and Nab-Pacliarc 100 mg Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Nab-Pacliarc 100 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelEtanercept
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
When Etanercept is used with Nab-Pacliarc 100 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Nab-Pacliarc 100 mg Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PaclitaxelCladribine
Severe
How does the drug interact with Nab-Pacliarc 100 mg Injection:
Combining Cladribine with Nab-Pacliarc 100 mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Taking Nab-Pacliarc 100 mg Injection with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Nab-Pacliarc 100 mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consuming alcohol while taking Nab-Pacliarc 100 mg Injection may worsen side effects such as fatigue and nausea. Consult your doctor if you have concerns regarding it.

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Pregnancy

Unsafe

Nab-Pacliarc 100 mg Injection must not be given during pregnancy unless clearly necessary, as it may cause birth defects. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Nab-Pacliarc 100 mg Injection.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Nab-Pacliarc 100 mg Injection. Do not restart breastfeeding until your doctor tells you it is safe to do so.

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Driving

Caution

Nab-Pacliarc 100 mg Injection may cause tiredness. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Do not use Nab-Pacliarc 100 mg Injection if you have severe liver problems. If you have a history of liver disease, inform your doctor before receiving Nab-Pacliarc 100 mg Injection.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Nab-Pacliarc 100 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Consult your doctor before giving Nab-Pacliarc 100 mg Injection to children under 18 years of age, as safety and effectiveness data is limited.

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Heart

Exercise caution before using Nab-Pacliarc 100 mg Injection in case of heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Nab-Pacliarc 100 mg Injection can be used in the elderly when prescribed by a doctor. If you have any concerns about using Nab-Pacliarc 100 mg Injection, please consult a doctor.

Have a query?

FAQs

Nab-Pacliarc 100 mg Injection is used in the treatment of cancer, including breast cancer, pancreatic cancer, and non-small cell lung cancer.

Nab-Pacliarc 100 mg Injection contains Paclitaxel and Human Albumin, which work together to combat cancer. Paclitaxel stops cell division and prevents the growth of certain cancer cells by stabilizing microtubules, while human albumin acts as a carrier protein, delivering paclitaxel to cancer cells and enhancing its effectiveness.

The most common side effect of Nab-Pacliarc 100 mg Injection is hair loss. The hair may grow back after the treatment with Nab-Pacliarc 100 mg Injection is finished. However, consult your doctor if you have any concerns.

Yes, Nab-Pacliarc 100 mg Injection is cytotoxic. It works by interfering with the growth of cancer cells, preventing them from dividing and causing them to die. However, its cytotoxic nature also means it can affect normal, healthy cells, potentially leading to side effects.

The common side effects of Nab-Pacliarc 100 mg Injection include numbness or tingling in hands and feet, tiredness, nausea and vomiting, diarrhea, hair loss, joint and muscle pain, swelling in hands or feet, and fever. Not everyone will experience all of these side effects, and they typically resolve once the treatment is stopped. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - NAB0042

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021660s037lbl.pdf
  2. https://packageinserts.bms.com/ppi/ppi_abraxane.pdf
  3. https://www.drugs.com/drug-interactions/paclitaxel.html
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC4161504/

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