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  3. N-Adrin 4 mg Injection 2 ml

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N-Adrin 4 mg Injection 2 ml, Pack of 1 Injection
N-Adrin 4 mg Injection 2 ml, Pack of 1 Injection
N-Adrin 4 mg Injection 2 ml, Pack of 1 Injection
N-Adrin 4 mg Injection 2 ml, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

N-Adrin 4mg/2ml Injection is used to treat low blood pressure. It contains Norepinephrine that works by constricting and narrowing blood vessels; thus, increasing blood pressure. In some cases, this medicine may cause side effects such as headaches, anxiety, tremors, difficulty in breathing, vomiting, high blood pressure, or urinary retention. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym :

NORADRENALINE

Composition :

NOREPINEPHRINE-4MG

Manufacturer/Marketer :

AAA Pharma Trade Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About N-Adrin 4mg/2ml Injection

N-Adrin 4mg/2ml Injection belongs to a class of medications called antihypotensives primarily used to treat hypotensive (low blood pressure) emergencies. Hypotension is a condition in which the blood flows through the blood vessels at lower than normal pressures. Low blood pressure symptoms include tiredness, dizziness, light-headedness, loss of consciousness, nausea, depression, blurry vision, or clammy (wet or sweaty) skin.

N-Adrin 4mg/2ml Injection contains Norepinephrine that works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it increases heart rate and blood pressure.

You are advised to take N-Adrin 4mg/2ml Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience headaches, anxiety, tremor, difficulty in breathing, vomiting, high blood pressure, or urinary retention. Most of these side effects of N-Adrin 4mg/2ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to N-Adrin 4mg/2ml Injection or any other medicines, please tell your doctor. Please consult a doctor if you are pregnant or breastfeeding before taking N-Adrin 4mg/2ml Injection. N-Adrin 4mg/2ml Injection is not recommended for children. If you have irregular heartbeats, hyperthyroidism (overactive thyroid gland), diabetes, angina pectoris (chest pain), vascular blockage in limbs or stomach, any heart problems, or if you recently had a heart attack, inform your doctor before taking N-Adrin 4mg/2ml Injection. If it is essential to administer N-Adrin 4mg/2ml Injection simultaneously as plasma or blood transfusion, plasma or blood may be administered in a separate drip.

Uses of N-Adrin 4mg/2ml Injection

N-Adrin 4mg/2ml Injection is used to treat hypotension (low blood pressure). The detailed uses of N-Adrin 4mg/2ml Injection are as follows:

  • Treatment of Hypotension: N-Adrin 4mg/2ml Injection treats severe low blood pressure in critical care settings, stabilising vital signs.
  • Management of Shock: N-Adrin 4mg/2ml Injection helps to manage shock by improving blood pressure and circulation.
  • Cardiac Support During Surgery: N-Adrin 4mg/2ml Injection supports heart function and maintains blood pressure during surgery, especially for patients with cardiovascular issues.
  • Vasopressor Therapy: N-Adrin 4mg/2ml Injection acts as a vasopressor, constricting blood vessels and increasing blood pressure, crucial for critically ill patients.
  • Support in Anaesthesia: N-Adrin 4mg/2ml Injection maintains stable blood pressure during anaesthesia, countering its potential lowering effects.

Have a query?

Directions for Use

  • Your doctor will determine the dosage and timing of N-Adrin 4mg/2ml Injection based on your health condition.
  • N-Adrin 4mg/2ml Injection is administered by a doctor or nurse in a hospital.
  • Do not self-administer it.

Medicinal Benefits

N-Adrin 4mg/2ml Injection contains Norepinephrine used in the treatment of hypotensive (low blood pressure) emergencies. N-Adrin 4mg/2ml Injection constricts and narrows blood vessels by acting on alpha receptors that cause muscle contractions. Thus, N-Adrin 4mg/2ml Injection redirects blood to heart and brain by narrowing blood vessels in the extremities, which increases heart rate and blood pressure. N-Adrin 4mg/2ml Injection is used to restore blood pressure to normal in emergencies that require an immediate rise in blood pressure to a normal level.

How N-Adrin 4mg/2ml Injection Works

N-Adrin 4mg/2ml Injection contains Norepinephrine that works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it increases heart rate and blood pressure.

Storage

• Store in a cool and dry place away from sunlight.• Keep N-Adrin 4mg/2ml Injection out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of N-Adrin 4 mg Injection 2 ml
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

What if I have taken an overdose of N-Adrin 4mg/2ml Injection

Since N-Adrin 4mg/2ml Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience symptoms of overdose such as severe headache, vomiting, sweating, slow heartbeats, stabbing chest pain, pale skin, and sensitivity to light.

Drug Warnings

If you are allergic to N-Adrin 4mg/2ml Injection or any other medicines, please tell your doctor. Please consult a doctor if you are pregnant or breastfeeding before taking N-Adrin 4mg/2ml Injection. N-Adrin 4mg/2ml Injection is not recommended for children. If you have irregular heartbeats, hyperthyroidism (overactive thyroid gland), diabetes, angina pectoris (chest pain) or any vascular blockage in limbs or stomach, any heart problems, or if you recently had a heart attack, inform your doctor before taking N-Adrin 4mg/2ml Injection. If it is essential to administer N-Adrin 4mg/2ml Injection at the same time as plasma or blood transfusion, plasma or blood may be administered in a separate drip. N-Adrin 4mg/2ml Injection is not recommended for patients suffering from low blood pressure caused by hypovolaemia (low blood volume).

Drug-Drug Interactions

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NorepinephrineClomipramine
Severe
NorepinephrineDoxepin
Severe

Drug-Drug Interactions

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NorepinephrineClomipramine
Severe
How does the drug interact with N-Adrin 4 mg Injection 2 ml:
Clomipramine can enhance the effects of N-Adrin 4 mg Injection 2 ml on blood pressure.

How to manage the interaction:
There may be a possibility of interaction between N-Adrin 4 mg Injection 2 ml and Clomipramine, but it can be taken if prescribed by a doctor. It's important to keep an eye on your blood pressure regularly. Do not stop using any medications without talking to a doctor.
NorepinephrineDoxepin
Severe
How does the drug interact with N-Adrin 4 mg Injection 2 ml:
Doxepin can enhance the effects of N-Adrin 4 mg Injection 2 ml on blood vessel constriction.

How to manage the interaction:
Although taking Doxepin and N-Adrin 4 mg Injection 2 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
NorepinephrineAmitriptyline
Severe
How does the drug interact with N-Adrin 4 mg Injection 2 ml:
Co-administration of Amitriptyline and N-Adrin 4 mg Injection 2 ml may lead to unusual side effects.

How to manage the interaction:
N-Adrin 4 mg Injection 2 ml and amitriptyline could interact, but they can still be taken if they are prescribed by a doctor. N-Adrin 4 mg Injection 2 ml and amitriptyline shouldn't be combined unless a medical emergency arises. Even when you are lying down or have your head up, it is crucial to keep a watchful eye on your blood pressure. Also, keep an eye out for any unusual side effects. Without consulting a doctor, never stop taking any medications.
NorepinephrineNortriptyline
Severe
How does the drug interact with N-Adrin 4 mg Injection 2 ml:
Nortriptyline can enhance the effects of N-Adrin 4 mg Injection 2 ml on blood pressure.

How to manage the interaction:
Although taking N-Adrin 4 mg Injection 2 ml and Nortriptyline together can cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your blood pressure regularly. Do not stop using any medications without a doctor's advice.
NorepinephrineTirzepatide
Moderate
How does the drug interact with N-Adrin 4 mg Injection 2 ml:
N-Adrin 4 mg Injection 2 ml may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.
  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
  • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
  • Eat foods rich in folates such as beans, asparagus, lentils, leafy greens, citrus fruits, liver, and eggs.
  • Try to eat smoked fish, canned soup, pickled items, cottage cheese, and olives as salty foods can also increase blood pressure.
  • Take frequent breaks if you exercise outdoors in extreme heat.
  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES

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Alcohol

Caution

Interaction of N-Adrin 4mg/2ml Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using N-Adrin 4mg/2ml Injection.

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Pregnancy

Caution

N-Adrin 4mg/2ml Injection is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

N-Adrin 4mg/2ml Injection is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking N-Adrin 4mg/2ml Injection. However, N-Adrin 4mg/2ml Injection is generally given for hospitalised patients.

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Liver

Caution

N-Adrin 4mg/2ml Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

N-Adrin 4mg/2ml Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

N-Adrin 4mg/2ml Injection is not recommended for children as the safety and effectiveness were not established.

FAQs

N-Adrin 4mg/2ml Injection is used to treat hypotensive (low blood pressure) emergencies.

N-Adrin 4mg/2ml Injection contains Norepinephrine that works by constricting and narrowing blood vessels by acting on alpha receptors that causes muscle contractions. Thus, it increases heart rate and blood pressure.

You are not recommended to take duloxetine (antidepressant) with N-Adrin 4mg/2ml Injection as co-administration of these two medicines may increase the risk of high blood pressure and heart rate. However, please consult your doctor before taking other medicines with N-Adrin 4mg/2ml Injection.

N-Adrin 4mg/2ml Injection should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking N-Adrin 4mg/2ml Injection so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

You are recommended to take N-Adrin 4mg/2ml Injection with caution if you have diabetes as it may increase blood sugar levels. Therefore, it is advised to inform your doctor if you have diabetes before taking N-Adrin 4mg/2ml Injection.

N-Adrin 4mg/2ml Injection may cause a headache as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.

N-Adrin 4mg/2ml Injection may have an impact on fertility, although the effects are not fully understood. It could potentially affect ovarian function and sperm quality, which are important factors in conception. If you're trying to get pregnant or experiencing difficulty conceiving, it's essential to consult a healthcare professional or fertility specialist.

N-Adrin 4mg/2ml Injection is not recommended for children as the safety and effectiveness were not established. Consult a doctor for appropriate suitable treatment for your child.

N-Adrin 4mg/2ml Injection may interact with antidepressants (imipramine, duloxetine, venlafaxine, phenelzine, moclobemide), antibiotics (linezolid), and methemoglobinemia antidote (methylene blue). Always consult your healthcare provider before starting or stopping any medication to ensure there are no harmful interactions.

The common side effects of the N-Adrin 4mg/2ml Injection are headache, anxiety, tremors, difficulty in breathing, vomiting, high blood pressure, and urinary retention. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Your doctor will determine the appropriate treatment duration for N-Adrin 4mg/2ml Injection based on your health needs and status.

N-Adrin 4mg/2ml Injection will be administered by a healthcare professional; do not self-administer.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Country of origin

India

Manufacturer/Marketer address

E-11, MOTI NAGAR , NEW DELHI-110015
Other Info - NAD0011

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 30, 2025 | 7:27 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.8776.pdf
  2. https://www.drugs.com/mtm/norepinephrine.html

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